ATE437880T1 - Dimere azacyclische verbindungen und deren verwendung - Google Patents
Dimere azacyclische verbindungen und deren verwendungInfo
- Publication number
- ATE437880T1 ATE437880T1 AT05716605T AT05716605T ATE437880T1 AT E437880 T1 ATE437880 T1 AT E437880T1 AT 05716605 T AT05716605 T AT 05716605T AT 05716605 T AT05716605 T AT 05716605T AT E437880 T1 ATE437880 T1 AT E437880T1
- Authority
- AT
- Austria
- Prior art keywords
- diseases
- disorders
- dimere
- nervous system
- disorders related
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/13—Dicarboxylic acids
- C07C57/15—Fumaric acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200400170 | 2004-02-04 | ||
| US54175204P | 2004-02-05 | 2004-02-05 | |
| PCT/EP2005/050403 WO2005075479A1 (en) | 2004-02-04 | 2005-02-01 | Dimeric azacyclic compounds and their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE437880T1 true ATE437880T1 (de) | 2009-08-15 |
Family
ID=34839642
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05716605T ATE437880T1 (de) | 2004-02-04 | 2005-02-01 | Dimere azacyclische verbindungen und deren verwendung |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7674899B2 (de) |
| EP (1) | EP1713809B1 (de) |
| JP (1) | JP2007520525A (de) |
| AT (1) | ATE437880T1 (de) |
| DE (1) | DE602005015682D1 (de) |
| WO (1) | WO2005075479A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1976828T (pt) | 2005-12-29 | 2017-03-10 | Celtaxsys Inc | Derivados de diamina como inibidores de leucotrieno a4 hidrolase |
| CA2637530A1 (en) * | 2006-01-18 | 2007-09-07 | Siena Biotech S.P.A. | Modulators of alpha7 nicotinic acetylcholine receptors and therapeutic uses thereof |
| US7728031B2 (en) * | 2006-02-24 | 2010-06-01 | Abbott Laboratories | Octahydro-pyrrolo[3,4-b]pyrrole derivatives |
| WO2008067121A2 (en) * | 2006-11-07 | 2008-06-05 | Lexicon Pharmaceuticals, Inc. | Methods of treating cognitive impairment and dementia |
| TW200901974A (en) | 2007-01-16 | 2009-01-16 | Wyeth Corp | Compounds, compositions, and methods of making and using them |
| EP2188288A1 (de) | 2007-09-11 | 2010-05-26 | Abbott Laboratories | Octahydropyrrolo[3,4-b]pyrrol-n-oxide |
| AU2014249168B2 (en) | 2013-03-12 | 2018-07-12 | Celltaxis, Llc | Methods of inhibiting leukotriene A4 hydrolase |
| JP6534650B2 (ja) | 2013-03-14 | 2019-06-26 | セルタクシス，インコーポレイテッド | ロイコトリエンａ４加水分解酵素の阻害剤 |
| AU2014239585B2 (en) | 2013-03-14 | 2019-04-04 | Celtaxsys, Inc. | Inhibitors of leukotriene A4 hydrolase |
| CA2906035A1 (en) | 2013-03-14 | 2014-09-25 | Celtaxsys, Inc. | Inhibitors of leukotriene a4 hydrolase |
| JP6612874B2 (ja) | 2014-12-16 | 2019-11-27 | アクソファント サイエンシーズ ゲーエムベーハー | α７−ニコチン性アセチルコリン受容体のアゴニストとしてのジェミナル置換キヌクリジンアミド化合物 |
| US10370370B2 (en) | 2015-06-10 | 2019-08-06 | Axovant Sciences Gmbh | Aminobenzisoxazole compounds as agonists of α7-nicotinic acetylcholine receptors |
| US10428062B2 (en) | 2015-08-12 | 2019-10-01 | Axovant Sciences Gmbh | Geminal substituted aminobenzisoxazole compounds as agonists of α7-nicotinic acetylcholine receptors |
| HUE053744T2 (hu) | 2016-05-17 | 2021-07-28 | Scandion Oncology As | A rák kombinált kezelése |
| AU2019278935A1 (en) | 2018-05-31 | 2020-12-10 | Celltaxis, Llc | Method of reducing pulmonary exacerbations in respiratory disease patients |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5929247A (en) * | 1994-10-24 | 1999-07-27 | Eli Lilly And Company | Heterocyclic compounds and their preparation and use |
| GB0010955D0 (en) | 2000-05-05 | 2000-06-28 | Novartis Ag | Organic compounds |
| US6579878B1 (en) | 2000-07-07 | 2003-06-17 | Targacept, Inc. | Pharmaceutical compositions and methods for use |
| JP2005505506A (ja) * | 2001-06-12 | 2005-02-24 | イーラン ファーマスーティカルズ、インコーポレイテッド | アルツハイマー病の治療に有用な大環状分子 |
| CA2503786A1 (en) * | 2002-11-01 | 2004-05-13 | Pharmacia & Upjohn Company Llc | Compounds having both alpha7 nicotinic agonist activity and 5ht, antagonist activity for treatment of cns diseases |
| WO2004058272A1 (en) | 2002-12-20 | 2004-07-15 | Control Delivery Systems, Inc. | Steroid compositions for intraocular use |
| DE602004023586D1 (de) | 2003-02-27 | 2009-11-26 | Neurosearch As | Neue diazabicyclische arylderivate |
-
2005
- 2005-02-01 DE DE602005015682T patent/DE602005015682D1/de active Active
- 2005-02-01 WO PCT/EP2005/050403 patent/WO2005075479A1/en not_active Application Discontinuation
- 2005-02-01 US US10/586,838 patent/US7674899B2/en not_active Expired - Fee Related
- 2005-02-01 JP JP2006551843A patent/JP2007520525A/ja active Pending
- 2005-02-01 AT AT05716605T patent/ATE437880T1/de not_active IP Right Cessation
- 2005-02-01 EP EP05716605A patent/EP1713809B1/de not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| DE602005015682D1 (de) | 2009-09-10 |
| JP2007520525A (ja) | 2007-07-26 |
| US20080242668A1 (en) | 2008-10-02 |
| US7674899B2 (en) | 2010-03-09 |
| WO2005075479A1 (en) | 2005-08-18 |
| EP1713809A1 (de) | 2006-10-25 |
| EP1713809B1 (de) | 2009-07-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE437880T1 (de) | Dimere azacyclische verbindungen und deren verwendung | |
| DE60318860D1 (de) | Chinucledin - derivate und deren verwendung | |
| ATE477253T1 (de) | Neuartige oxadiazol-derivate und deren medizinische verwendung | |
| ATE385497T1 (de) | 3-substituierte quinuclidin-derivate und deren verwendung als nikotinischen agonisten | |
| ATE481407T1 (de) | Neue diazabicyclische arylderivate und medizinische verwendung dafür | |
| MX2007004269A (es) | Derivados de arilo diazabiciclico nuevos y su uso medico. | |
| DE60310548D1 (de) | Diazabicyclische biarylderivate | |
| ATE450263T1 (de) | Diazabicyclische aryl-derivate als cholinerge rezeptor-modulatoren | |
| MX2010001135A (es) | Nuevos derivados de 1,2,3-triazol, utiles como modulares de receptores de acetilcolina nicotinicos. | |
| WO2006087306A3 (en) | Diazabicyclic aryl derivatives and their use as cholinergic ligands at the nicotinic acetylcholine receptors | |
| ATE287888T1 (de) | Aryl- und heteroaryldiazabicycloalkane, deren zubereitung und verwendung | |
| ATE455114T1 (de) | Enantiomerenreine chinuclidinyloxy-pyridazine und ihre verwendung als nikotin-acetylcholin- rezeptorliganden | |
| DK1562945T3 (da) | Hidtil ukendte diazebicykliske biarylderivater | |
| ATE473978T1 (de) | Neue diazabicyclische arylderivate und medizinische verwendung dafür | |
| HK1079528A1 (en) | Azacyclic ethynyl derivatives | |
| ATE341548T1 (de) | Neue verbindungen, deren herstellung und verwendung | |
| MXPA05006861A (es) | Derivados arildiazabiciclicos novedosos. | |
| DE60307102D1 (de) | 3-substituierte chinuklidine und deren verwendung | |
| MX2007003331A (es) | Nuevos derivados de arilo diazabiciclico. | |
| ATE460416T1 (de) | Neuartige 1,4-diazabicycloä3.2.2ünonan-derivate und deren medizinische verwendung | |
| ATE495178T1 (de) | Diazabicyclische arylderivate und ihre verwendung als chinolinergische liganden an nikotin- acetylcholin-rezeptoren | |
| DE602004031124D1 (de) | Neue chinuklidinderivative und deren pharmazeutische verwendung | |
| ATE478869T1 (de) | Diazabicycloalkan-derivate und ihre medizinische verwendung | |
| MX2007004245A (es) | Nuevos derivados de arilo azabiciclicos y su uso medico. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |