IL98176A0 - Bicyclic 1-aza-cycloalkanes,their preparation and pharmaceutical compositions containing them - Google Patents

Bicyclic 1-aza-cycloalkanes,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL98176A0
IL98176A0 IL98176A IL9817691A IL98176A0 IL 98176 A0 IL98176 A0 IL 98176A0 IL 98176 A IL98176 A IL 98176A IL 9817691 A IL9817691 A IL 9817691A IL 98176 A0 IL98176 A0 IL 98176A0
Authority
IL
Israel
Prior art keywords
cycloalkanes
aza
bicyclic
preparation
pharmaceutical compositions
Prior art date
Application number
IL98176A
Other languages
English (en)
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of IL98176A0 publication Critical patent/IL98176A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL98176A 1990-05-19 1991-05-17 Bicyclic 1-aza-cycloalkanes,their preparation and pharmaceutical compositions containing them IL98176A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4016212 1990-05-19
DE4018886 1990-06-13

Publications (1)

Publication Number Publication Date
IL98176A0 true IL98176A0 (en) 1992-06-21

Family

ID=25893382

Family Applications (1)

Application Number Title Priority Date Filing Date
IL98176A IL98176A0 (en) 1990-05-19 1991-05-17 Bicyclic 1-aza-cycloalkanes,their preparation and pharmaceutical compositions containing them

Country Status (14)

Country Link
EP (1) EP0458214A1 (xx)
JP (1) JP2853837B2 (xx)
KR (1) KR910020009A (xx)
AU (1) AU648789B2 (xx)
CA (1) CA2042860A1 (xx)
CZ (1) CZ281837B6 (xx)
FI (1) FI912409A (xx)
HU (1) HUT58091A (xx)
IE (1) IE911688A1 (xx)
IL (1) IL98176A0 (xx)
NO (1) NO911934L (xx)
PT (1) PT97703A (xx)
SK (1) SK279168B6 (xx)
YU (1) YU84791A (xx)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0456519T3 (da) * 1990-05-11 1994-11-07 Sankyo Co Piperidyloxy- og quinuclidinyloxyisoxazolderivater, deres fremstilling og deres terapeutiske anvendelse
GB9122988D0 (en) * 1991-10-30 1991-12-18 Ici Plc Heterocyclic compounds
GB9127279D0 (en) * 1991-12-23 1992-02-19 Ici Plc Heterocyclic derivatives
JPH06508377A (ja) * 1992-04-10 1994-09-22 ゼネカ　リミテッド ヘテロ環式化合物
GB9211796D0 (en) * 1992-06-04 1992-07-15 Ici Plc Heterocyclic derivatives
IT1255179B (it) * 1992-06-26 1995-10-20 Enzo Cereda Azaciclo e azabiciclo alchiliden idrossilamine
GB9216721D0 (en) * 1992-08-06 1992-09-23 Ici Plc Therapeutic heterocyclic derivatives
GB9218334D0 (en) * 1992-08-28 1992-10-14 Ici Plc Heterocyclic compounds
IL107184A (en) * 1992-10-09 1997-08-14 Abbott Lab Heterocyclic ether compounds that enhance cognitive function
DE4236331A1 (de) * 1992-10-28 1994-05-05 Boehringer Ingelheim Kg Synergistische Kombination
GB9226573D0 (en) * 1992-12-21 1993-02-17 Ici Plc Heterocyclic compounds
IL109451A0 (en) * 1993-04-29 1994-07-31 Zeneca Ltd Heterocyclic derivatives
US5998404A (en) * 1994-10-24 1999-12-07 Eli Lilly And Company Heterocyclic compounds and their use
US5512574A (en) * 1994-12-21 1996-04-30 American Home Products Corporation Quinuclidine and azabicyclo 2.2.1! heptane pyrazinyl ethers as muscarinic agonists
US5859004A (en) * 1995-02-17 1999-01-12 Novo Nordisk A/S Use of heterocyclic compounds for the treatment of conditions caused by malfunctioning of the nicotinic cholinergic system
US6040442A (en) * 1995-06-01 2000-03-21 Eli Lilly And Company Process for preparing 1,2,5-thiadiazole containing ethers
US5998434A (en) * 1995-12-06 1999-12-07 Eli Lilly And Company Composition for treating pain
EP0912183A4 (en) * 1996-04-23 1999-08-04 Lilly Co Eli HETEROCYCLIC COMPOSITIONS
US20050245567A1 (en) * 2002-08-14 2005-11-03 Dan Peters Novel quinuclidine derivatives and their use
GB0220581D0 (en) 2002-09-04 2002-10-09 Novartis Ag Organic Compound
US7750022B2 (en) 2003-08-13 2010-07-06 Neurosearch A/S Quinuclidine derivatives and their pharmaceutical use
US7160876B2 (en) 2003-12-22 2007-01-09 Abbott Laboratories Fused bicycloheterocycle substituted quinuclidine derivatives
US7655657B2 (en) 2003-12-22 2010-02-02 Abbott Laboratories Fused bicycloheterocycle substituted quinuclidine derivatives
US20050137203A1 (en) * 2003-12-22 2005-06-23 Jianguo Ji 3-quinuclidinyl amino-substituted biaryl derivatives
AR049401A1 (es) * 2004-06-18 2006-07-26 Novartis Ag Aza-biciclononanos
GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds
JP2008523058A (ja) * 2004-12-10 2008-07-03 アボット・ラボラトリーズ 縮合ビシクロ複素環置換キヌクリジン誘導体
GB0521508D0 (en) 2005-10-21 2005-11-30 Novartis Ag Organic compounds
GB0525673D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
GB0525672D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
TWI794742B (zh) 2020-02-18 2023-03-01 美商基利科學股份有限公司 抗病毒化合物
EP4323362A1 (en) 2021-04-16 2024-02-21 Gilead Sciences, Inc. Methods of preparing carbanucleosides using amides

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE321933B (xx) * 1967-10-05 1970-03-23 Astra Ab
FR2014831A1 (en) * 1968-08-01 1970-04-24 Sogeras Quinuclidinyl and quinuclidinylalkyl ethers with cholino - lytic, antihistaminic and neurosedative activity
GB8615785D0 (en) * 1986-06-27 1986-08-06 Beecham Group Plc Compounds
ATE133415T1 (de) * 1987-04-15 1996-02-15 Beecham Group Plc Am brückenkopf substituierte azabicyclenderivate
CA1307790C (en) * 1987-08-04 1992-09-22 Ian Anthony Cliffe Ethers
GB8718445D0 (en) * 1987-08-04 1987-09-09 Wyeth John & Brother Ltd Pyridyl-ethers
DE3839385A1 (de) * 1988-11-22 1990-05-23 Boehringer Ingelheim Kg Neue quinuclidine, ihre herstellung als arzneimittel und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
JP2853837B2 (ja) 1999-02-03
IE911688A1 (en) 1991-11-20
SK279168B6 (sk) 1998-07-08
AU648789B2 (en) 1994-05-05
AU7713091A (en) 1991-11-21
JPH04226981A (ja) 1992-08-17
CA2042860A1 (en) 1991-11-20
FI912409A (fi) 1991-11-20
FI912409A0 (fi) 1991-05-17
HU911663D0 (en) 1991-11-28
YU84791A (xx) 1994-06-10
HUT58091A (en) 1992-01-28
CZ281837B6 (cs) 1997-02-12
NO911934L (no) 1991-11-20
EP0458214A1 (de) 1991-11-27
PT97703A (pt) 1992-02-28
KR910020009A (ko) 1991-12-19
CS144891A3 (en) 1992-05-13
NO911934D0 (no) 1991-05-16

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