CR5826A - Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion - Google Patents

Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion

Info

Publication number
CR5826A
CR5826A CR5826A CR5826A CR5826A CR 5826 A CR5826 A CR 5826A CR 5826 A CR5826 A CR 5826A CR 5826 A CR5826 A CR 5826A CR 5826 A CR5826 A CR 5826A
Authority
CR
Costa Rica
Prior art keywords
procedure
coating
excipient
solution
obtaining
Prior art date
Application number
CR5826A
Other languages
English (en)
Inventor
Picornell Daldel Carlos
Original Assignee
Intexim S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8300432&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR5826(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Intexim S A filed Critical Intexim S A
Publication of CR5826A publication Critical patent/CR5826A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

un nucleo inerte, una capa activa soluble o de desintegracion rapida en agua obtenida a partir de una unica solucion-suspension acuosa o hidroalcoholica que comprende: un principio activo de actividad antiulcerosa de formula I, II o III, y por lo menos un excipiente, y una capa de recubrimiento externa gastrorresistente obtenida a partir de una solucion que comprende un polimero de recubrimiento enterico y por lo menos un excipiente. El procedimiento se lleva a cabo mediante un recubrimiento de los nucleos inertes mediante la nebulizacion de la unica suspension-solucion acuosa o hidroalcoholica, un secado de la capa activa formada durante la nebulizacion de la etapa anterior y un recubrimiento de los nucleos cargados mediante la nebulizacion de una solucion que comprende un polýimero de recubrimiento enterico con por lo menos un excipiente para obtener una capa de recubrimiento externa gastrorresistente.
CR5826A 1997-07-31 1998-07-24 Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion CR5826A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES009701816A ES2137862B1 (es) 1997-07-31 1997-07-31 Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion.

Publications (1)

Publication Number Publication Date
CR5826A true CR5826A (es) 1998-09-28

Family

ID=8300432

Family Applications (1)

Application Number Title Priority Date Filing Date
CR5826A CR5826A (es) 1997-07-31 1998-07-24 Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion

Country Status (33)

Country Link
US (1) US20020098242A1 (es)
EP (1) EP1010423B1 (es)
JP (1) JP3961217B2 (es)
KR (1) KR100591488B1 (es)
AR (1) AR013242A1 (es)
AT (1) ATE317688T1 (es)
AU (1) AU751609B2 (es)
BG (1) BG64967B1 (es)
CA (1) CA2307037C (es)
CR (1) CR5826A (es)
CZ (1) CZ298700B6 (es)
DE (1) DE69833490T2 (es)
DK (1) DK1010423T3 (es)
ES (3) ES2137862B1 (es)
GT (1) GT199800113A (es)
HN (1) HN1998000113A (es)
HR (1) HRP20000053B1 (es)
HU (1) HU230635B1 (es)
IL (1) IL134158A (es)
MY (1) MY121353A (es)
NO (1) NO20000435L (es)
NZ (1) NZ502590A (es)
PA (1) PA8456401A1 (es)
PE (1) PE105199A1 (es)
PL (1) PL192961B1 (es)
PT (1) PT1010423E (es)
RU (1) RU2207114C2 (es)
SK (1) SK284892B6 (es)
TR (1) TR200000264T2 (es)
TW (1) TW533201B (es)
UA (1) UA66800C2 (es)
WO (1) WO1999006032A2 (es)
ZA (1) ZA986893B (es)

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Also Published As

Publication number Publication date
ZA986893B (en) 1999-01-27
ES2256943T4 (es) 2007-09-16
AR013242A1 (es) 2000-12-13
HUP0002524A2 (hu) 2001-08-28
BG104193A (en) 2000-09-29
NZ502590A (en) 2001-08-31
US20020098242A1 (en) 2002-07-25
SK1032000A3 (en) 2000-11-07
DE69833490T2 (de) 2006-10-19
ES2156699A1 (es) 2001-07-01
JP3961217B2 (ja) 2007-08-22
CZ2000344A3 (cs) 2000-06-14
HRP20000053B1 (en) 2003-10-31
HN1998000113A (es) 2000-01-06
IL134158A0 (en) 2001-04-30
UA66800C2 (uk) 2004-06-15
HRP20000053A2 (en) 2000-08-31
JP2001511443A (ja) 2001-08-14
CZ298700B6 (cs) 2007-12-27
CA2307037A1 (en) 1999-02-11
EP1010423A2 (en) 2000-06-21
WO1999006032A2 (es) 1999-02-11
PE105199A1 (es) 1999-11-19
PL192961B1 (pl) 2006-12-29
ES2256943T3 (es) 2006-07-16
DK1010423T3 (da) 2006-05-22
TR200000264T2 (tr) 2000-09-21
PT1010423E (pt) 2006-06-30
NO20000435L (no) 2000-03-23
PL338613A1 (en) 2000-11-06
KR100591488B1 (ko) 2006-06-22
EP1010423B1 (en) 2006-02-15
CA2307037C (en) 2006-09-12
PA8456401A1 (es) 2000-09-29
WO1999006032A3 (es) 1999-08-12
ES2137862B1 (es) 2000-09-16
AU8217398A (en) 1999-02-22
DE69833490D1 (de) 2006-04-20
MY121353A (en) 2006-01-28
KR20010022439A (ko) 2001-03-15
ES2137862A1 (es) 1999-12-16
GT199800113A (es) 2000-01-18
RU2207114C2 (ru) 2003-06-27
TW533201B (en) 2003-05-21
ES2156699B1 (es) 2002-03-01
SK284892B6 (sk) 2006-02-02
IL134158A (en) 2004-08-31
BG64967B1 (bg) 2006-11-30
AU751609B2 (en) 2002-08-22
ATE317688T1 (de) 2006-03-15
HU230635B1 (hu) 2017-05-29
HUP0002524A3 (en) 2002-12-28
NO20000435D0 (no) 2000-01-27

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