HUP0002524A2 - Fekélyellenes hatóanyagot tartalmazó orális gyógyászati készítmények és eljárás azok előállítására - Google Patents
Fekélyellenes hatóanyagot tartalmazó orális gyógyászati készítmények és eljárás azok előállításáraInfo
- Publication number
- HUP0002524A2 HUP0002524A2 HU0002524A HUP0002524A HUP0002524A2 HU P0002524 A2 HUP0002524 A2 HU P0002524A2 HU 0002524 A HU0002524 A HU 0002524A HU P0002524 A HUP0002524 A HU P0002524A HU P0002524 A2 HUP0002524 A2 HU P0002524A2
- Authority
- HU
- Hungary
- Prior art keywords
- coating
- medicinal preparations
- production
- formula
- layer
- Prior art date
Links
- 230000000767 anti-ulcer Effects 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 239000008183 oral pharmaceutical preparation Substances 0.000 title 1
- 239000011248 coating agent Substances 0.000 abstract 3
- 238000000576 coating method Methods 0.000 abstract 3
- 239000010410 layer Substances 0.000 abstract 3
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 3
- 238000002360 preparation method Methods 0.000 abstract 3
- 229920000642 polymer Polymers 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 239000011247 coating layer Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000005507 spraying Methods 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pretreatment Of Seeds And Plants (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
A találmány fekélyellenes hatóanyagot tartalmazó orális gyógyá- szatikészítményekre és azok előállítására alkalmas eljárásra vonatkozik. Atalálmány szerinti gyógyászati készítmények magukban foglalnak (a)inert magokat; (b) a magokon vízben oldódó vagy vízben gyorsan szétesőréteget, amely gyógyászati szempontból elfogadható segédanyag(ok)mellett (I) általános képletű, (II) képletű vagy (III) képletűhatóanyagot tartalmaz; és (c) egy, a gyomorban uralkodó körülményekközött ellenállóképes külső bevonatot, amely - bélben oldódó,bevonatképző polimert; és - legalább egy segédanyagot tartalmaz. Atalálmány szerinti gyógyászati készítményeket úgy állítják elő, hogyaz inert magokat egyetlen vizes vagy vizes-alkoholos szuszpenzióoldatfelszórásával bevonják; a felszórt aktív réteget megszárítják; és agyomorban uralkodó körülmények között ellenállóképes külsőbevonatréteg kialakítása céljából az aktívréteggel rendelkező magotbevonják olyan oldat felszórásával, amely bélben oldódó polimerbevonóanyag mellett legalább egy, farmakológiai szempontbólelfogadható segédanyagot tartalmaz. Ó
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES009701816A ES2137862B1 (es) | 1997-07-31 | 1997-07-31 | Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion. |
ESP9701816 | 1997-07-31 | ||
PCT/ES1998/000204 WO1999006032A2 (es) | 1997-07-31 | 1998-07-13 | Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP0002524A2 true HUP0002524A2 (hu) | 2001-08-28 |
HUP0002524A3 HUP0002524A3 (en) | 2002-12-28 |
HU230635B1 HU230635B1 (hu) | 2017-05-29 |
Family
ID=8300432
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0002524A HU230635B1 (hu) | 1997-07-31 | 1998-07-13 | Eljárás fekélyellenes hatóanyagot tartalmazó orális gyógyászati készítmények előállítására |
Country Status (33)
Country | Link |
---|---|
US (1) | US20020098242A1 (hu) |
EP (1) | EP1010423B1 (hu) |
JP (1) | JP3961217B2 (hu) |
KR (1) | KR100591488B1 (hu) |
AR (1) | AR013242A1 (hu) |
AT (1) | ATE317688T1 (hu) |
AU (1) | AU751609B2 (hu) |
BG (1) | BG64967B1 (hu) |
CA (1) | CA2307037C (hu) |
CR (1) | CR5826A (hu) |
CZ (1) | CZ298700B6 (hu) |
DE (1) | DE69833490T2 (hu) |
DK (1) | DK1010423T3 (hu) |
ES (3) | ES2137862B1 (hu) |
GT (1) | GT199800113A (hu) |
HN (1) | HN1998000113A (hu) |
HR (1) | HRP20000053B1 (hu) |
HU (1) | HU230635B1 (hu) |
IL (1) | IL134158A (hu) |
MY (1) | MY121353A (hu) |
NO (1) | NO20000435L (hu) |
NZ (1) | NZ502590A (hu) |
PA (1) | PA8456401A1 (hu) |
PE (1) | PE105199A1 (hu) |
PL (1) | PL192961B1 (hu) |
PT (1) | PT1010423E (hu) |
RU (1) | RU2207114C2 (hu) |
SK (1) | SK284892B6 (hu) |
TR (1) | TR200000264T2 (hu) |
TW (1) | TW533201B (hu) |
UA (1) | UA66800C2 (hu) |
WO (1) | WO1999006032A2 (hu) |
ZA (1) | ZA986893B (hu) |
Families Citing this family (65)
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US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
US6096340A (en) * | 1997-11-14 | 2000-08-01 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
US6733778B1 (en) | 1999-08-27 | 2004-05-11 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
US6432448B1 (en) | 1999-02-08 | 2002-08-13 | Fmc Corporation | Edible coating composition |
US6723342B1 (en) | 1999-02-08 | 2004-04-20 | Fmc Corporation | Edible coating composition |
FR2793688B1 (fr) | 1999-05-21 | 2003-06-13 | Ethypharm Lab Prod Ethiques | Microgranules gastroproteges, procede d'obtention et preparations pharmaceutiques |
IL130602A0 (en) * | 1999-06-22 | 2000-06-01 | Dexcel Ltd | Stable benzimidazole formulation |
US6228400B1 (en) * | 1999-09-28 | 2001-05-08 | Carlsbad Technology, Inc. | Orally administered pharmaceutical formulations of benzimidazole derivatives and the method of preparing the same |
US6500462B1 (en) | 1999-10-29 | 2002-12-31 | Fmc Corporation | Edible MCC/PGA coating composition |
IT1319655B1 (it) | 2000-11-15 | 2003-10-23 | Eurand Int | Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione. |
WO2002043694A2 (en) | 2000-11-28 | 2002-06-06 | Fmc Corporation | Edible pga(propylene glycol alginate) coating composition |
US9358214B2 (en) | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
KR100447085B1 (ko) * | 2001-11-08 | 2004-09-04 | 바램제약주식회사 | 마그네슘이온, 칼슘이온 또는 철이온이 고농도로 결합된알긴산의 제조 방법 |
KR20050044545A (ko) * | 2001-11-21 | 2005-05-12 | 에자이 가부시키가이샤 | 산에 불안정한 생리활성 화합물을 함유하는 제제 조성물및 그 제법 |
US20050163846A1 (en) * | 2001-11-21 | 2005-07-28 | Eisai Co., Ltd. | Preparation composition containing acid-unstable physiologically active compound, and process for producing same |
US6663888B2 (en) | 2001-12-14 | 2003-12-16 | Eurand Pharmaceuticals Ltd. | Pulsatile release histamine H2 antagonist dosage form |
BR0313173A (pt) * | 2002-08-02 | 2007-07-17 | Ratiopharm Gmbh | preparação farmacêutica que contém um composto de benzimidazol misto com celulose microcristalina, método para sua preparação, bem como uso da dita celulose microcristalina |
CA2503150A1 (en) * | 2002-10-31 | 2004-05-21 | Supergen, Inc. | Pharmaceutical formulations targeting specific regions of the gastrointestinal tract |
US8367111B2 (en) | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
ES2665464T3 (es) * | 2003-03-28 | 2018-04-25 | Sigmoid Pharma Limited | Forma de dosificación oral sólida que contiene microcápsulas sin costuras |
WO2005007115A2 (en) * | 2003-07-18 | 2005-01-27 | Santarus, Inc. | Pharmaceutical composition for inhibiting acid secretion |
RU2381813C2 (ru) | 2004-03-22 | 2010-02-20 | Зольвай Фармасьютиклз Гмбх | Пероральные фармацевтические композиции на основе продуктов, содержащих липазы, прежде всего панкреатин, и пав |
NZ549838A (en) * | 2004-03-26 | 2010-04-30 | Eisai R&D Man Co Ltd | Coated controlled-release preparation containing a gastric acid secretion inhibitor |
US7709025B2 (en) | 2004-03-31 | 2010-05-04 | Bpsi Holdings, Inc. | Enteric coatings for orally ingestible substrates |
US8747895B2 (en) | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
EP2444071A1 (en) * | 2004-09-27 | 2012-04-25 | Sigmoid Pharma Limited | Minicapsule formulations |
US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
NZ589750A (en) | 2004-10-21 | 2012-07-27 | Aptalis Pharmatech Inc | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
BRPI0500586A (pt) * | 2005-02-21 | 2006-10-10 | Fundacao Oswaldo Cruz | composição farmacêutica, processo para preparar dita composição, uso da respectiva composição no tratamento da imunodeficiência causada por infecção pelo hiv e respectivo método de tratamento |
WO2006111980A2 (en) * | 2005-04-20 | 2006-10-26 | Ideal Cures Pvt. Ltd. | Pva based film coating and film coating compositions |
US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
JP5140586B2 (ja) | 2005-07-29 | 2013-02-06 | アボット プロダクツ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 滅菌パンクレアチン粉末の製法 |
US9198871B2 (en) | 2005-08-15 | 2015-12-01 | Abbott Products Gmbh | Delayed release pancreatin compositions |
US11266607B2 (en) | 2005-08-15 | 2022-03-08 | AbbVie Pharmaceuticals GmbH | Process for the manufacture and use of pancreatin micropellet cores |
US20090148519A1 (en) * | 2005-09-29 | 2009-06-11 | Yasuhiro Zaima | Pulsed-release preparation having improved disintegration properties in vivo |
US10072256B2 (en) | 2006-05-22 | 2018-09-11 | Abbott Products Gmbh | Process for separating and determining the viral load in a pancreatin sample |
US20100105738A1 (en) * | 2006-10-06 | 2010-04-29 | Mitsuru Mizuno | Extended release formulations of a proton pump inhibitor |
US8221747B2 (en) | 2007-02-20 | 2012-07-17 | Aptalis Pharma Limited | Stable pancreatic enzyme compositions |
EP2066309B1 (en) * | 2007-04-04 | 2012-08-29 | Sigmoid Pharma Limited | An oral pharmaceutical composition |
EP2061587A1 (en) * | 2007-04-26 | 2009-05-27 | Sigmoid Pharma Limited | Manufacture of multiple minicapsules |
CA2685593A1 (en) * | 2007-05-01 | 2008-11-06 | Sigmoid Pharma Limited | Combination pharmaceutical compositions |
CA2704826A1 (en) * | 2007-11-27 | 2009-06-04 | Ohara Pharmaceutical Co., Ltd. | Method for producing granulated preparation |
US10087493B2 (en) | 2008-03-07 | 2018-10-02 | Aptalis Pharma Canada Ulc | Method for detecting infectious parvovirus in pharmaceutical preparations |
US20110038933A1 (en) * | 2008-05-06 | 2011-02-17 | Dexcell Ltd. | Stable benzimidazole formulation |
US8840934B2 (en) * | 2009-01-02 | 2014-09-23 | Rainbow Pharmaceutical Sa | Uses of ammonium chloride |
CA2762179A1 (en) | 2009-05-18 | 2010-11-25 | Sigmoid Pharma Limited | Composition comprising oil drops |
CN107582526A (zh) | 2009-08-12 | 2018-01-16 | 希格默伊德药业有限公司 | 包含聚合物基质和油相的免疫调节组合物 |
ES2668203T3 (es) | 2009-12-02 | 2018-05-17 | Adare Pharmaceuticals S.R.L. | Microcápsulas de fexofenadina y composiciones que las contienen |
US20110217426A1 (en) * | 2010-03-04 | 2011-09-08 | Perry Stephen C | Enteric coating composition |
EA029101B1 (ru) | 2010-10-01 | 2018-02-28 | Апталис Фарма Лимитид | Составы с низкой дозой панкрелипазы и кишечнорастворимым покрытием |
GB201020032D0 (en) | 2010-11-25 | 2011-01-12 | Sigmoid Pharma Ltd | Composition |
EP2714015B1 (en) * | 2011-06-01 | 2017-03-15 | FMC Corporation | Controlled release solid dose forms |
US10953025B2 (en) * | 2011-07-14 | 2021-03-23 | Able Cerebral, Llc | Composition, device and method for delayed and sustained release of brain energy molecules |
WO2013010137A2 (en) * | 2011-07-14 | 2013-01-17 | Jacks Health Technologies Llc | A composition, device and method for delayed and sustained release of brain energy molecules |
US9976171B2 (en) | 2011-08-08 | 2018-05-22 | Allergan Pharmaceuticals International Limited | Method for dissolution testing of solid compositions containing digestive enzymes |
GB201212010D0 (en) | 2012-07-05 | 2012-08-22 | Sigmoid Pharma Ltd | Formulations |
ES2784227T3 (es) | 2013-08-09 | 2020-09-23 | Allergan Pharmaceuticals Int Ltd | Composición de enzimas digestivos adecuada para la administración entérica |
GB201319791D0 (en) | 2013-11-08 | 2013-12-25 | Sigmoid Pharma Ltd | Formulations |
AU2015275860A1 (en) | 2014-06-19 | 2016-11-03 | Aptalis Pharma Ltd. | Methods for removing viral contaminants from pancreatic extracts |
MX2014008314A (es) * | 2014-07-07 | 2016-01-06 | Andres Abelino Choza Romero | Procedimiento para mezclar sustancias, mediante nebulizacion. |
TWI535784B (zh) | 2014-08-26 | 2016-06-01 | 財團法人工業技術研究院 | 剪切增稠配方、及包含其之複合材料 |
AU2015341695B2 (en) | 2014-11-07 | 2021-07-08 | Sublimity Therapeutics Limited | Compositions comprising cyclosporin |
EP3288556A4 (en) | 2015-04-29 | 2018-09-19 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
CZ2017315A3 (cs) | 2017-06-02 | 2018-12-12 | Zentiva, K.S. | Dávkovací jednotka s PPI (inhibitory protonové pumpy) |
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US2799241A (en) * | 1949-01-21 | 1957-07-16 | Wisconsin Alumni Res Found | Means for applying coatings to tablets or the like |
JPS517116A (en) * | 1974-06-11 | 1976-01-21 | Shinetsu Chemical Co | Choyoseihifukuyakuzaino seizohoho |
CA1327010C (en) * | 1986-02-13 | 1994-02-15 | Tadashi Makino | Stabilized solid pharmaceutical composition containing antiulcer benzimidazole compound and its production |
GB2189698A (en) * | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated omeprazole tablets |
GB2189699A (en) * | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated acid-labile medicaments |
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US5232706A (en) * | 1990-12-31 | 1993-08-03 | Esteve Quimica, S.A. | Oral pharmaceutical preparation containing omeprazol |
YU48263B (sh) * | 1991-06-17 | 1997-09-30 | Byk Gulden Lomberg Chemische Fabrik Gmbh. | Postupak za dobijanje farmaceutskog preparata na bazi pantoprazola |
ATE156707T1 (de) * | 1991-06-21 | 1997-08-15 | Ilsan Ilac Ve Hammaddeleri San | Neues galenisches verfahren für omeprazol enthaltende pellets |
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-
1997
- 1997-07-31 ES ES009701816A patent/ES2137862B1/es not_active Expired - Fee Related
-
1998
- 1998-07-07 TW TW087110962A patent/TW533201B/zh not_active IP Right Cessation
- 1998-07-13 KR KR1020007001023A patent/KR100591488B1/ko not_active IP Right Cessation
- 1998-07-13 CZ CZ20000344A patent/CZ298700B6/cs not_active IP Right Cessation
- 1998-07-13 AU AU82173/98A patent/AU751609B2/en not_active Expired
- 1998-07-13 ES ES98932185T patent/ES2256943T4/es not_active Expired - Lifetime
- 1998-07-13 TR TR2000/00264T patent/TR200000264T2/xx unknown
- 1998-07-13 PT PT98932185T patent/PT1010423E/pt unknown
- 1998-07-13 AT AT98932185T patent/ATE317688T1/de active
- 1998-07-13 CA CA002307037A patent/CA2307037C/en not_active Expired - Lifetime
- 1998-07-13 NZ NZ502590A patent/NZ502590A/en not_active IP Right Cessation
- 1998-07-13 RU RU2000104866/14A patent/RU2207114C2/ru not_active IP Right Cessation
- 1998-07-13 HU HU0002524A patent/HU230635B1/hu unknown
- 1998-07-13 WO PCT/ES1998/000204 patent/WO1999006032A2/es active IP Right Grant
- 1998-07-13 SK SK103-2000A patent/SK284892B6/sk unknown
- 1998-07-13 EP EP98932185A patent/EP1010423B1/en not_active Revoked
- 1998-07-13 DE DE69833490T patent/DE69833490T2/de not_active Expired - Lifetime
- 1998-07-13 PL PL338613A patent/PL192961B1/pl unknown
- 1998-07-13 IL IL13415898A patent/IL134158A/en not_active IP Right Cessation
- 1998-07-13 UA UA2000020750A patent/UA66800C2/uk unknown
- 1998-07-13 JP JP2000504847A patent/JP3961217B2/ja not_active Expired - Lifetime
- 1998-07-13 DK DK98932185T patent/DK1010423T3/da active
- 1998-07-22 AR ARP980103576A patent/AR013242A1/es unknown
- 1998-07-23 HN HN1998000113A patent/HN1998000113A/es unknown
- 1998-07-23 PE PE1998000660A patent/PE105199A1/es not_active Application Discontinuation
- 1998-07-24 CR CR5826A patent/CR5826A/es not_active Application Discontinuation
- 1998-07-27 GT GT199800113A patent/GT199800113A/es unknown
- 1998-07-28 MY MYPI98003435A patent/MY121353A/en unknown
- 1998-07-30 PA PA19988456401A patent/PA8456401A1/es unknown
- 1998-07-31 ZA ZA986893A patent/ZA986893B/xx unknown
-
1999
- 1999-01-27 ES ES009900157A patent/ES2156699B1/es not_active Expired - Fee Related
-
2000
- 2000-01-26 US US09/491,624 patent/US20020098242A1/en not_active Abandoned
- 2000-01-27 NO NO20000435A patent/NO20000435L/no not_active Application Discontinuation
- 2000-01-31 HR HR20000053A patent/HRP20000053B1/xx not_active IP Right Cessation
- 2000-02-25 BG BG104193A patent/BG64967B1/bg unknown
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