HUP0002524A2 - Fekélyellenes hatóanyagot tartalmazó orális gyógyászati készítmények és eljárás azok előállítására - Google Patents

Fekélyellenes hatóanyagot tartalmazó orális gyógyászati készítmények és eljárás azok előállítására

Info

Publication number
HUP0002524A2
HUP0002524A2 HU0002524A HUP0002524A HUP0002524A2 HU P0002524 A2 HUP0002524 A2 HU P0002524A2 HU 0002524 A HU0002524 A HU 0002524A HU P0002524 A HUP0002524 A HU P0002524A HU P0002524 A2 HUP0002524 A2 HU P0002524A2
Authority
HU
Hungary
Prior art keywords
coating
medicinal preparations
production
formula
layer
Prior art date
Application number
HU0002524A
Other languages
English (en)
Inventor
Carlos Picornell Darder
Original Assignee
Liconsa, Liberación Controlada de Sustancias Activas, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8300432&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0002524(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Liconsa, Liberación Controlada de Sustancias Activas, S.A. filed Critical Liconsa, Liberación Controlada de Sustancias Activas, S.A.
Publication of HUP0002524A2 publication Critical patent/HUP0002524A2/hu
Publication of HUP0002524A3 publication Critical patent/HUP0002524A3/hu
Publication of HU230635B1 publication Critical patent/HU230635B1/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A találmány fekélyellenes hatóanyagot tartalmazó orális gyógyá- szatikészítményekre és azok előállítására alkalmas eljárásra vonatkozik. Atalálmány szerinti gyógyászati készítmények magukban foglalnak (a)inert magokat; (b) a magokon vízben oldódó vagy vízben gyorsan szétesőréteget, amely gyógyászati szempontból elfogadható segédanyag(ok)mellett (I) általános képletű, (II) képletű vagy (III) képletűhatóanyagot tartalmaz; és (c) egy, a gyomorban uralkodó körülményekközött ellenállóképes külső bevonatot, amely - bélben oldódó,bevonatképző polimert; és - legalább egy segédanyagot tartalmaz. Atalálmány szerinti gyógyászati készítményeket úgy állítják elő, hogyaz inert magokat egyetlen vizes vagy vizes-alkoholos szuszpenzióoldatfelszórásával bevonják; a felszórt aktív réteget megszárítják; és agyomorban uralkodó körülmények között ellenállóképes külsőbevonatréteg kialakítása céljából az aktívréteggel rendelkező magotbevonják olyan oldat felszórásával, amely bélben oldódó polimerbevonóanyag mellett legalább egy, farmakológiai szempontbólelfogadható segédanyagot tartalmaz. Ó
HU0002524A 1997-07-31 1998-07-13 Eljárás fekélyellenes hatóanyagot tartalmazó orális gyógyászati készítmények előállítására HU230635B1 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES009701816A ES2137862B1 (es) 1997-07-31 1997-07-31 Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion.
ESP9701816 1997-07-31
PCT/ES1998/000204 WO1999006032A2 (es) 1997-07-31 1998-07-13 Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion

Publications (3)

Publication Number Publication Date
HUP0002524A2 true HUP0002524A2 (hu) 2001-08-28
HUP0002524A3 HUP0002524A3 (en) 2002-12-28
HU230635B1 HU230635B1 (hu) 2017-05-29

Family

ID=8300432

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0002524A HU230635B1 (hu) 1997-07-31 1998-07-13 Eljárás fekélyellenes hatóanyagot tartalmazó orális gyógyászati készítmények előállítására

Country Status (33)

Country Link
US (1) US20020098242A1 (hu)
EP (1) EP1010423B1 (hu)
JP (1) JP3961217B2 (hu)
KR (1) KR100591488B1 (hu)
AR (1) AR013242A1 (hu)
AT (1) ATE317688T1 (hu)
AU (1) AU751609B2 (hu)
BG (1) BG64967B1 (hu)
CA (1) CA2307037C (hu)
CR (1) CR5826A (hu)
CZ (1) CZ298700B6 (hu)
DE (1) DE69833490T2 (hu)
DK (1) DK1010423T3 (hu)
ES (3) ES2137862B1 (hu)
GT (1) GT199800113A (hu)
HN (1) HN1998000113A (hu)
HR (1) HRP20000053B1 (hu)
HU (1) HU230635B1 (hu)
IL (1) IL134158A (hu)
MY (1) MY121353A (hu)
NO (1) NO20000435L (hu)
NZ (1) NZ502590A (hu)
PA (1) PA8456401A1 (hu)
PE (1) PE105199A1 (hu)
PL (1) PL192961B1 (hu)
PT (1) PT1010423E (hu)
RU (1) RU2207114C2 (hu)
SK (1) SK284892B6 (hu)
TR (1) TR200000264T2 (hu)
TW (1) TW533201B (hu)
UA (1) UA66800C2 (hu)
WO (1) WO1999006032A2 (hu)
ZA (1) ZA986893B (hu)

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Also Published As

Publication number Publication date
CZ2000344A3 (cs) 2000-06-14
CA2307037C (en) 2006-09-12
NO20000435L (no) 2000-03-23
JP2001511443A (ja) 2001-08-14
HUP0002524A3 (en) 2002-12-28
UA66800C2 (uk) 2004-06-15
PT1010423E (pt) 2006-06-30
PE105199A1 (es) 1999-11-19
ES2156699B1 (es) 2002-03-01
CA2307037A1 (en) 1999-02-11
KR20010022439A (ko) 2001-03-15
IL134158A (en) 2004-08-31
NO20000435D0 (no) 2000-01-27
AU8217398A (en) 1999-02-22
BG64967B1 (bg) 2006-11-30
SK1032000A3 (en) 2000-11-07
DK1010423T3 (da) 2006-05-22
PA8456401A1 (es) 2000-09-29
PL192961B1 (pl) 2006-12-29
ES2137862B1 (es) 2000-09-16
IL134158A0 (en) 2001-04-30
DE69833490T2 (de) 2006-10-19
EP1010423A2 (en) 2000-06-21
ZA986893B (en) 1999-01-27
HRP20000053A2 (en) 2000-08-31
ES2137862A1 (es) 1999-12-16
BG104193A (en) 2000-09-29
ATE317688T1 (de) 2006-03-15
KR100591488B1 (ko) 2006-06-22
GT199800113A (es) 2000-01-18
HU230635B1 (hu) 2017-05-29
AU751609B2 (en) 2002-08-22
AR013242A1 (es) 2000-12-13
WO1999006032A3 (es) 1999-08-12
ES2256943T3 (es) 2006-07-16
HN1998000113A (es) 2000-01-06
MY121353A (en) 2006-01-28
TW533201B (en) 2003-05-21
EP1010423B1 (en) 2006-02-15
NZ502590A (en) 2001-08-31
ES2156699A1 (es) 2001-07-01
HRP20000053B1 (en) 2003-10-31
WO1999006032A2 (es) 1999-02-11
TR200000264T2 (tr) 2000-09-21
US20020098242A1 (en) 2002-07-25
JP3961217B2 (ja) 2007-08-22
RU2207114C2 (ru) 2003-06-27
PL338613A1 (en) 2000-11-06
ES2256943T4 (es) 2007-09-16
CR5826A (es) 1998-09-28
DE69833490D1 (de) 2006-04-20
CZ298700B6 (cs) 2007-12-27
SK284892B6 (sk) 2006-02-02

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