CR20120294A - Compuestos tricíclicos novedosos - Google Patents

Compuestos tricíclicos novedosos

Info

Publication number
CR20120294A
CR20120294A CR20120294A CR20120294A CR20120294A CR 20120294 A CR20120294 A CR 20120294A CR 20120294 A CR20120294 A CR 20120294A CR 20120294 A CR20120294 A CR 20120294A CR 20120294 A CR20120294 A CR 20120294A
Authority
CR
Costa Rica
Prior art keywords
tricyclic compounds
new tricyclic
compounds
new
prodrugs
Prior art date
Application number
CR20120294A
Other languages
English (en)
Inventor
Neil Wishart
Maria A Argiriadi
Eric C Breninlinger
David J Calderwood
Anna M Ericsson
Bryan A Fiamengo
Kristine E Frank
Michael Friedman
Dawn M George
Eric R Goedken
Nathan S Josephsohn
Biqin C Li
Michael J Morytko
Kelly D Mullen
Gagandeep Somal
Kent D Stewart
Jeffrey W Voss
Grier A Wallace
Lu Wang
Kevin R Woller
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44115273&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR20120294(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of CR20120294A publication Critical patent/CR20120294A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems

Abstract

Un compuesto con la Fórmula (Ia), (Ib), (Ic), (Id), (Ie), (Si), (Ig), (Ih), (Ii), (Ij), (Ik), o (Il), según se las define aquí, sales farmacéuticamente aceptables, prodrogas, metabolitos, estereoisómeros e isómeros de los mismos biológicamente activos, donde las variables se han definido aquí. Los compuestos de la invención son útiles para tratar condiciones inmunológicas y oncológicas.
CR20120294A 2009-12-01 2012-05-30 Compuestos tricíclicos novedosos CR20120294A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26559109P 2009-12-01 2009-12-01

Publications (1)

Publication Number Publication Date
CR20120294A true CR20120294A (es) 2012-09-03

Family

ID=44115273

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20120294A CR20120294A (es) 2009-12-01 2012-05-30 Compuestos tricíclicos novedosos

Country Status (20)

Country Link
US (2) US8785639B2 (es)
EP (1) EP2506713A4 (es)
JP (1) JP2013512282A (es)
KR (1) KR20120102724A (es)
CN (1) CN102711470A (es)
AU (1) AU2010326030A1 (es)
CA (1) CA2781010A1 (es)
CL (1) CL2012001396A1 (es)
CR (1) CR20120294A (es)
DO (1) DOP2012000149A (es)
EC (1) ECSP12011968A (es)
GT (1) GT201200167A (es)
IL (1) IL220053A0 (es)
MX (1) MX2012006381A (es)
NZ (1) NZ599938A (es)
PE (1) PE20130005A1 (es)
RU (1) RU2012127368A (es)
SG (1) SG181147A1 (es)
WO (1) WO2011068899A1 (es)
ZA (1) ZA201203588B (es)

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AU2010326030A1 (en) 2012-06-07
GT201200167A (es) 2014-06-10
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US20140349970A1 (en) 2014-11-27
US20110190489A1 (en) 2011-08-04
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RU2012127368A (ru) 2014-01-10
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DOP2012000149A (es) 2012-09-30
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PE20130005A1 (es) 2013-02-16
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