CR11749A - Tratamiento de la disnea asociada con insuficiencia cardiaca aguda con relaxina - Google Patents
Tratamiento de la disnea asociada con insuficiencia cardiaca aguda con relaxinaInfo
- Publication number
- CR11749A CR11749A CR11749A CR11749A CR11749A CR 11749 A CR11749 A CR 11749A CR 11749 A CR11749 A CR 11749A CR 11749 A CR11749 A CR 11749A CR 11749 A CR11749 A CR 11749A
- Authority
- CR
- Costa Rica
- Prior art keywords
- relaxin
- treatment
- disnea
- acute cardiac
- cardiac insufficiency
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2221—Relaxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/64—Relaxins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La descripción pertenece a los métodos para reducir la descompensación a través de la intervención aguda, incluyendo en los sujetos afligidos con insuficiencia cardiaca aguda descompensada. Particularmente, la descripción proporciona métodos para el tratamiento de la descompensación cardiaca aguda, mediante la administración de una cantidad farmacéuticamente efectiva de relaxina
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12788908P | 2008-05-16 | 2008-05-16 | |
US19054508P | 2008-08-28 | 2008-08-28 | |
US20124008P | 2008-12-08 | 2008-12-08 | |
US16433309P | 2009-03-27 | 2009-03-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
CR11749A true CR11749A (es) | 2011-02-11 |
Family
ID=40834101
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR11749A CR11749A (es) | 2008-05-16 | 2010-10-22 | Tratamiento de la disnea asociada con insuficiencia cardiaca aguda con relaxina |
Country Status (30)
Country | Link |
---|---|
US (7) | US8415301B2 (es) |
EP (2) | EP2288373B1 (es) |
JP (4) | JP5651586B2 (es) |
CN (3) | CN103212063B (es) |
AR (1) | AR071810A1 (es) |
AU (1) | AU2009246114B2 (es) |
BR (1) | BRPI0913011A2 (es) |
CA (1) | CA2724540C (es) |
CR (1) | CR11749A (es) |
CY (1) | CY1116925T1 (es) |
DK (1) | DK2288373T3 (es) |
EA (2) | EA201500552A1 (es) |
ES (1) | ES2546287T3 (es) |
GB (2) | GB2459983B (es) |
HK (5) | HK1139051A1 (es) |
HR (1) | HRP20150845T1 (es) |
HU (1) | HUE025483T2 (es) |
IL (3) | IL208992A (es) |
MA (1) | MA32389B1 (es) |
MX (1) | MX2010012450A (es) |
MY (2) | MY159803A (es) |
NZ (3) | NZ701038A (es) |
PL (1) | PL2288373T3 (es) |
PT (1) | PT2288373E (es) |
SG (2) | SG191587A1 (es) |
SI (1) | SI2288373T1 (es) |
TW (1) | TWI386202B (es) |
UA (1) | UA99953C2 (es) |
WO (1) | WO2009140659A2 (es) |
ZA (1) | ZA201007449B (es) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2459983B (en) * | 2008-05-16 | 2010-04-28 | Corthera Inc | Methods of treating dyspnea associated with acute heart failure |
CA2724535A1 (en) * | 2008-05-16 | 2009-11-19 | Elaine Unemori | Use of relaxin to treat chronic heart failure |
BR112012022654A2 (pt) * | 2010-03-10 | 2016-11-01 | Univ Florida | modulação de aquaporinas com relaxina |
EP2601532B1 (en) * | 2010-08-06 | 2016-01-27 | Mycartis N.V. | Perlecan as a biomarker for renal dysfunction |
MA34521B1 (fr) | 2010-08-17 | 2013-09-02 | Ambrx Inc | Polypeptides de relaxine modifiés et leurs utilisations |
US9567386B2 (en) | 2010-08-17 | 2017-02-14 | Ambrx, Inc. | Therapeutic uses of modified relaxin polypeptides |
JP2014522641A (ja) * | 2011-07-01 | 2014-09-08 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | リラキシン融合ポリペプチドおよびその使用 |
WO2013059879A1 (en) * | 2011-10-26 | 2013-05-02 | Howard Florey Institute Of Experimental Physiology And Medicine | Compositions and methods for the treatment of fibrosis and fibrotic diseases |
EP2814513B1 (en) * | 2012-02-14 | 2017-12-20 | The Regents of The University of California | Systemic delivery and regulated expression of paracrine genes for cardiovascular diseases and other conditions |
ES2929283T3 (es) | 2012-05-04 | 2022-11-28 | Us Health | Moduladores del receptor de relaxina 1 |
TR201807636T4 (tr) | 2012-10-26 | 2018-06-21 | Chiesi Farm Spa | Kalp yetmezliğinde kan basıncının kontrol edilmesi ve dispnenin azaltılması için yöntemler. |
AU2014248164B2 (en) | 2013-04-05 | 2019-05-23 | Scpharmaceuticals, Inc. | Pharmaceutical formulations for subcutaneous administration of furosemide |
US9707154B2 (en) | 2013-04-24 | 2017-07-18 | Corning Incorporated | Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients |
CN106031247A (zh) * | 2014-02-03 | 2016-10-12 | 诺华股份有限公司 | 用于输液装置的过滤器 |
EP2946788A1 (en) * | 2014-05-23 | 2015-11-25 | Immundiagnostik AG | Method and composition for treating heart failure with preserved ejection fraction |
KR20170018829A (ko) * | 2014-06-13 | 2017-02-20 | 노파르티스 아게 | Gdf-15를 감소시키기 위한 세렐락신의 용도 |
EP3387019B1 (en) | 2015-12-09 | 2021-10-20 | The Scripps Research Institute | Relaxin immunoglobulin fusion proteins and methods of use |
WO2017139164A1 (en) | 2016-02-12 | 2017-08-17 | Cardiac Pacemakers, Inc. | Systems and methods for patient monitoring |
TW201837051A (zh) | 2017-02-08 | 2018-10-16 | 美商必治妥美雅史谷比公司 | 包含藥物動力學增強劑之經修飾之鬆弛素(relaxin)多肽及其用途 |
US11832970B2 (en) | 2017-07-26 | 2023-12-05 | Cardiac Pacemakers, Inc. | Worsening heart failure stratification |
CN107335051A (zh) * | 2017-08-18 | 2017-11-10 | 温州医科大学附属第医院 | 一种保护慢性心衰肾功能的药物组合物 |
CN113271923A (zh) | 2019-01-04 | 2021-08-17 | Sq创新股份公司 | 呋塞米的药物组合物及其用途 |
CA3128033A1 (en) | 2019-01-31 | 2020-08-06 | Scpharmaceuticals Inc. | Concentrated liquid pharmaceutical formulations of furosemide and methods of administering the same |
WO2024047130A1 (en) | 2022-08-31 | 2024-03-07 | Relaxera Pharmazeutische Gesellschaft mbH & Co. KG | Immunosuppressive medicament and method of treatment |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5023321A (en) | 1982-12-13 | 1991-06-11 | Howard Florey Institute Of Experimental Physiology & Medicine | Molecular cloning and characterization of a further gene sequence coding for human relaxin |
US5478807A (en) * | 1991-08-19 | 1995-12-26 | Genentech, Inc. | Use of relaxin in the treatment of bradycardia |
US5166191A (en) * | 1991-08-19 | 1992-11-24 | Genentech, Inc. | Use of relaxin in cardiovascular therapy |
DE69432704T2 (de) | 1993-06-21 | 2004-02-26 | Genentech, Inc., South San Francisco | Verfahren zur Herstellung von humanen Relaxin |
WO1995003822A2 (en) | 1993-07-27 | 1995-02-09 | Mario Bigazzi | Use of relaxin as therapeutic or preventing agent |
US5760069A (en) | 1995-02-08 | 1998-06-02 | Boehringer Mannheim Pharmaceuticals Corporation-Smithkline Beecham Corporation Limited Partnership #1 | Method of treatment for decreasing mortality resulting from congestive heart failure |
US5811395A (en) | 1995-06-07 | 1998-09-22 | Medical University Of South Carolina | Relaxin analogs and derivatives methods and uses thereof |
WO1997006814A1 (en) | 1995-08-15 | 1997-02-27 | Connective Therapeutics, Inc. | Method of promoting angiogenesis |
AU2001236886A1 (en) | 2000-02-09 | 2001-08-20 | Connetics Corporation | Use of relaxin to treat diseases related to vasoconstriction |
DE10155843A1 (de) * | 2000-11-16 | 2003-01-30 | Immundiagnostik Ag | Verfahren zur Prognose und Diagnose von Herzinsuffizienz |
US20050113286A1 (en) * | 2002-03-18 | 2005-05-26 | Schreiner George F. | Methods for treating congestive heart failure |
US7878978B2 (en) | 2004-03-18 | 2011-02-01 | University Of Pittsburgh- Of The Commonwealth System Of Higher Education | Use of relaxin to increase arterial compliance |
KR100749857B1 (ko) * | 2004-03-30 | 2007-08-16 | 연세대학교 산학협력단 | 릴랙신 유전자를 포함하는 유전자 전달 시스템 및 릴랙신을이용한 약제학적 조성물 |
US20060264367A1 (en) * | 2005-05-21 | 2006-11-23 | Howard Florey Institute | Prevention of fibrosis following cardiac injury |
US20080077025A1 (en) * | 2005-07-11 | 2008-03-27 | Leticia Delgado-Herrera | Methods for determining how to treat congestive heart failure |
AU2008273813B2 (en) | 2007-07-12 | 2013-06-13 | Compugen Ltd. | Bioactive peptides and method of using same |
CA2724535A1 (en) | 2008-05-16 | 2009-11-19 | Elaine Unemori | Use of relaxin to treat chronic heart failure |
GB2459983B (en) * | 2008-05-16 | 2010-04-28 | Corthera Inc | Methods of treating dyspnea associated with acute heart failure |
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2009
- 2009-05-15 GB GB0908432A patent/GB2459983B/en not_active Expired - Fee Related
- 2009-05-15 HU HUE09747740A patent/HUE025483T2/en unknown
- 2009-05-15 AU AU2009246114A patent/AU2009246114B2/en not_active Ceased
- 2009-05-15 CN CN201310127326.6A patent/CN103212063B/zh not_active Expired - Fee Related
- 2009-05-15 ES ES09747740.0T patent/ES2546287T3/es active Active
- 2009-05-15 GB GB0918132A patent/GB2462221B/en not_active Expired - Fee Related
- 2009-05-15 JP JP2011509783A patent/JP5651586B2/ja not_active Expired - Fee Related
- 2009-05-15 DK DK09747740.0T patent/DK2288373T3/en active
- 2009-05-15 PL PL09747740T patent/PL2288373T3/pl unknown
- 2009-05-15 CA CA2724540A patent/CA2724540C/en not_active Expired - Fee Related
- 2009-05-15 MX MX2010012450A patent/MX2010012450A/es active IP Right Grant
- 2009-05-15 WO PCT/US2009/044249 patent/WO2009140659A2/en active Application Filing
- 2009-05-15 US US12/992,356 patent/US8415301B2/en not_active Expired - Fee Related
- 2009-05-15 NZ NZ701038A patent/NZ701038A/en not_active IP Right Cessation
- 2009-05-15 NZ NZ598709A patent/NZ598709A/xx not_active IP Right Cessation
- 2009-05-15 UA UAA201012879A patent/UA99953C2/uk unknown
- 2009-05-15 TW TW098116328A patent/TWI386202B/zh not_active IP Right Cessation
- 2009-05-15 NZ NZ589009A patent/NZ589009A/en not_active IP Right Cessation
- 2009-05-15 SG SG2013038260A patent/SG191587A1/en unknown
- 2009-05-15 US US12/467,214 patent/US8053411B2/en not_active Expired - Fee Related
- 2009-05-15 PT PT97477400T patent/PT2288373E/pt unknown
- 2009-05-15 EP EP09747740.0A patent/EP2288373B1/en active Active
- 2009-05-15 EA EA201500552A patent/EA201500552A1/ru unknown
- 2009-05-15 EP EP14167842.5A patent/EP2829280A1/en not_active Withdrawn
- 2009-05-15 AR ARP090101762A patent/AR071810A1/es unknown
- 2009-05-15 BR BRPI0913011A patent/BRPI0913011A2/pt not_active IP Right Cessation
- 2009-05-15 SI SI200931246T patent/SI2288373T1/sl unknown
- 2009-05-15 EA EA201001771A patent/EA022948B1/ru not_active IP Right Cessation
- 2009-05-15 SG SG10201609580YA patent/SG10201609580YA/en unknown
- 2009-05-15 CN CN201610565105.0A patent/CN106177914A/zh active Pending
- 2009-05-15 CN CN2009801177504A patent/CN102036679A/zh active Pending
- 2009-05-15 MY MYPI2010005049A patent/MY159803A/en unknown
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2010
- 2010-05-18 HK HK10104896.5A patent/HK1139051A1/xx not_active IP Right Cessation
- 2010-07-28 HK HK10107238.5A patent/HK1140693A1/xx not_active IP Right Cessation
- 2010-10-19 ZA ZA2010/07449A patent/ZA201007449B/en unknown
- 2010-10-22 CR CR11749A patent/CR11749A/es unknown
- 2010-10-28 IL IL208992A patent/IL208992A/en not_active IP Right Cessation
- 2010-12-10 MA MA33418A patent/MA32389B1/fr unknown
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2011
- 2011-05-30 HK HK11105324.3A patent/HK1151229A1/xx not_active IP Right Cessation
- 2011-05-30 HK HK15102533.3A patent/HK1202054A1/xx unknown
- 2011-09-23 US US13/242,012 patent/US8372809B2/en not_active Expired - Fee Related
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2012
- 2012-09-12 JP JP2012200728A patent/JP5638044B2/ja not_active Expired - Fee Related
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2013
- 2013-01-04 US US13/734,301 patent/US9066916B2/en not_active Expired - Fee Related
- 2013-03-05 US US13/784,963 patent/US9205132B2/en not_active Expired - Fee Related
- 2013-09-02 IL IL228244A patent/IL228244A/en not_active IP Right Cessation
- 2013-11-28 MY MYPI2013004312A patent/MY158327A/en unknown
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2014
- 2014-01-23 HK HK14100736.3A patent/HK1187550A1/zh not_active IP Right Cessation
- 2014-08-14 JP JP2014165276A patent/JP5875646B2/ja not_active Expired - Fee Related
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2015
- 2015-05-28 US US14/723,701 patent/US9579363B2/en not_active Expired - Fee Related
- 2015-08-10 HR HRP20150845TT patent/HRP20150845T1/hr unknown
- 2015-09-18 CY CY20151100824T patent/CY1116925T1/el unknown
- 2015-10-09 JP JP2015201153A patent/JP2016053040A/ja active Pending
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2016
- 2016-08-18 IL IL247351A patent/IL247351A0/en unknown
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2017
- 2017-01-23 US US15/412,447 patent/US20170151311A1/en not_active Abandoned
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