PL2288373T3 - Relaksyna do stosowania w leczeniu duszności powiązanej z ostrą niewydolnością serca - Google Patents

Relaksyna do stosowania w leczeniu duszności powiązanej z ostrą niewydolnością serca

Info

Publication number
PL2288373T3
PL2288373T3 PL09747740T PL09747740T PL2288373T3 PL 2288373 T3 PL2288373 T3 PL 2288373T3 PL 09747740 T PL09747740 T PL 09747740T PL 09747740 T PL09747740 T PL 09747740T PL 2288373 T3 PL2288373 T3 PL 2288373T3
Authority
PL
Poland
Prior art keywords
relaxin
treating
heart failure
acute heart
dyspnea associated
Prior art date
Application number
PL09747740T
Other languages
English (en)
Inventor
Elaine Unemori
Sam L Teichman
Gad Cotter
Dennis R Stewart
Martha Jo Whitehouse
Original Assignee
Corthera Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corthera Inc filed Critical Corthera Inc
Publication of PL2288373T3 publication Critical patent/PL2288373T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2221Relaxins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/64Relaxins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL09747740T 2008-05-16 2009-05-15 Relaksyna do stosowania w leczeniu duszności powiązanej z ostrą niewydolnością serca PL2288373T3 (pl)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US12788908P 2008-05-16 2008-05-16
US19054508P 2008-08-28 2008-08-28
US20124008P 2008-12-08 2008-12-08
US16433309P 2009-03-27 2009-03-27
EP09747740.0A EP2288373B1 (en) 2008-05-16 2009-05-15 Relaxin for use in treating of dyspnea associated with acute heart failure
PCT/US2009/044249 WO2009140659A2 (en) 2008-05-16 2009-05-15 Method of treating dyspnea associated with acute heart failure

Publications (1)

Publication Number Publication Date
PL2288373T3 true PL2288373T3 (pl) 2015-11-30

Family

ID=40834101

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09747740T PL2288373T3 (pl) 2008-05-16 2009-05-15 Relaksyna do stosowania w leczeniu duszności powiązanej z ostrą niewydolnością serca

Country Status (30)

Country Link
US (7) US8415301B2 (pl)
EP (2) EP2288373B1 (pl)
JP (4) JP5651586B2 (pl)
CN (3) CN103212063B (pl)
AR (1) AR071810A1 (pl)
AU (1) AU2009246114B2 (pl)
BR (1) BRPI0913011A2 (pl)
CA (1) CA2724540C (pl)
CR (1) CR11749A (pl)
CY (1) CY1116925T1 (pl)
DK (1) DK2288373T3 (pl)
EA (2) EA022948B1 (pl)
ES (1) ES2546287T3 (pl)
GB (2) GB2462221B (pl)
HK (5) HK1139051A1 (pl)
HR (1) HRP20150845T1 (pl)
HU (1) HUE025483T2 (pl)
IL (3) IL208992A (pl)
MA (1) MA32389B1 (pl)
MX (1) MX2010012450A (pl)
MY (2) MY159803A (pl)
NZ (3) NZ598709A (pl)
PL (1) PL2288373T3 (pl)
PT (1) PT2288373E (pl)
SG (2) SG191587A1 (pl)
SI (1) SI2288373T1 (pl)
TW (1) TWI386202B (pl)
UA (1) UA99953C2 (pl)
WO (1) WO2009140659A2 (pl)
ZA (1) ZA201007449B (pl)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2288373T3 (pl) * 2008-05-16 2015-11-30 Corthera Inc Relaksyna do stosowania w leczeniu duszności powiązanej z ostrą niewydolnością serca
BRPI0912559A2 (pt) * 2008-05-16 2015-10-13 Corthera Inc método de tratar insuficiência cardíaca crônica
AU2011224341B2 (en) 2010-03-10 2014-07-10 The University Of Florida Research Foundation, Inc. Modulating aquaporins with relaxin
US9465039B2 (en) 2010-08-06 2016-10-11 Mycartis Nv Perlecan as a biomarker for renal dysfunction
US9567386B2 (en) 2010-08-17 2017-02-14 Ambrx, Inc. Therapeutic uses of modified relaxin polypeptides
CA2808596C (en) 2010-08-17 2020-12-15 Ambrx, Inc. Modified relaxin polypeptides and their uses
US9382305B2 (en) * 2011-07-01 2016-07-05 Bayer Intellectual Property Gmbh Relaxin fusion polypeptides and uses thereof
WO2013059879A1 (en) * 2011-10-26 2013-05-02 Howard Florey Institute Of Experimental Physiology And Medicine Compositions and methods for the treatment of fibrosis and fibrotic diseases
EP2814513B1 (en) * 2012-02-14 2017-12-20 The Regents of The University of California Systemic delivery and regulated expression of paracrine genes for cardiovascular diseases and other conditions
US9452973B2 (en) 2012-05-04 2016-09-27 The United States Of America, As Represented By The Secretary Department Of Health And Human Services Modulators of the relaxin receptor 1
AU2013334081B2 (en) 2012-10-26 2017-05-18 Chiesi Farmaceutici S.P.A. Methods for controlling blood pressure and reducing dyspnea in heart failure
KR102493735B1 (ko) 2013-04-05 2023-01-30 에스씨파마슈티칼스 인코포레이티드 퓨로세마이드의 피하 투여용 약학 제형
US9707154B2 (en) 2013-04-24 2017-07-18 Corning Incorporated Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
AU2015212375B2 (en) * 2014-02-03 2018-07-05 Novartis Ag Filters for infusion sets
EP2946788A1 (en) 2014-05-23 2015-11-25 Immundiagnostik AG Method and composition for treating heart failure with preserved ejection fraction
MX2016016414A (es) * 2014-06-13 2017-04-10 Novartis Ag Uso de serelaxina para reducir gdf-15.
EP3387019B1 (en) 2015-12-09 2021-10-20 The Scripps Research Institute Relaxin immunoglobulin fusion proteins and methods of use
CN108697330B (zh) 2016-02-12 2022-07-15 心脏起搏器股份公司 用于患者监视的系统和方法
CN110637027A (zh) 2017-02-08 2019-12-31 百时美施贵宝公司 包含药代动力学增强子的修饰的松弛素多肽及其用途
US11832970B2 (en) 2017-07-26 2023-12-05 Cardiac Pacemakers, Inc. Worsening heart failure stratification
CN107335051A (zh) * 2017-08-18 2017-11-10 温州医科大学附属第医院 一种保护慢性心衰肾功能的药物组合物
WO2020141224A1 (en) 2019-01-04 2020-07-09 Sq Innovation Ag Pharmaceutical compositions of furosemide and uses thereof
AU2020214314A1 (en) 2019-01-31 2021-08-19 Scpharmaceuticals Inc. Concentrated liquid pharmaceutical formulations of furosemide and methods of administering the same
WO2024047130A1 (en) 2022-08-31 2024-03-07 Relaxera Pharmazeutische Gesellschaft mbH & Co. KG Immunosuppressive medicament and method of treatment

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5023321A (en) 1982-12-13 1991-06-11 Howard Florey Institute Of Experimental Physiology & Medicine Molecular cloning and characterization of a further gene sequence coding for human relaxin
US5478807A (en) 1991-08-19 1995-12-26 Genentech, Inc. Use of relaxin in the treatment of bradycardia
US5166191A (en) * 1991-08-19 1992-11-24 Genentech, Inc. Use of relaxin in cardiovascular therapy
EP0707650B1 (en) 1993-06-21 2003-05-21 Genentech, Inc. Process for producing human relaxin
CA2145515A1 (en) 1993-07-27 1995-02-09 Mario Bigazzi Use of relaxin as therapeutic or preventing agent
US5760069A (en) 1995-02-08 1998-06-02 Boehringer Mannheim Pharmaceuticals Corporation-Smithkline Beecham Corporation Limited Partnership #1 Method of treatment for decreasing mortality resulting from congestive heart failure
US5811395A (en) 1995-06-07 1998-09-22 Medical University Of South Carolina Relaxin analogs and derivatives methods and uses thereof
US6211147B1 (en) 1995-08-15 2001-04-03 Connetics Corporation Method of promoting angiogenesis using relaxin
EP1253929B1 (en) 2000-02-09 2007-05-23 BAS Medical, Inc. Use of relaxin to treat diseases related to vasoconstriction
DE10155843A1 (de) * 2000-11-16 2003-01-30 Immundiagnostik Ag Verfahren zur Prognose und Diagnose von Herzinsuffizienz
US20050113286A1 (en) 2002-03-18 2005-05-26 Schreiner George F. Methods for treating congestive heart failure
US7878978B2 (en) 2004-03-18 2011-02-01 University Of Pittsburgh- Of The Commonwealth System Of Higher Education Use of relaxin to increase arterial compliance
WO2006075819A1 (en) * 2004-03-30 2006-07-20 Industry-Academic Cooperation Foundation, Yonsei University Gene delivery system containing relaxin gene and pharmaceutical composition using relaxin
US20060264367A1 (en) 2005-05-21 2006-11-23 Howard Florey Institute Prevention of fibrosis following cardiac injury
US20080077025A1 (en) 2005-07-11 2008-03-27 Leticia Delgado-Herrera Methods for determining how to treat congestive heart failure
WO2009007848A2 (en) 2007-07-12 2009-01-15 Compugen Ltd. Bioactive peptides and method of using same
BRPI0912559A2 (pt) 2008-05-16 2015-10-13 Corthera Inc método de tratar insuficiência cardíaca crônica
PL2288373T3 (pl) * 2008-05-16 2015-11-30 Corthera Inc Relaksyna do stosowania w leczeniu duszności powiązanej z ostrą niewydolnością serca

Also Published As

Publication number Publication date
SG191587A1 (en) 2013-07-31
US20150320834A1 (en) 2015-11-12
US8372809B2 (en) 2013-02-12
CY1116925T1 (el) 2017-04-05
CA2724540C (en) 2014-07-08
MA32389B1 (fr) 2011-06-01
NZ589009A (en) 2012-05-25
MX2010012450A (es) 2011-03-21
CN106177914A (zh) 2016-12-07
AU2009246114A1 (en) 2009-11-19
JP2015013870A (ja) 2015-01-22
US20100048475A1 (en) 2010-02-25
US9579363B2 (en) 2017-02-28
IL247351A0 (en) 2016-09-29
DK2288373T3 (en) 2015-09-28
US20170151311A1 (en) 2017-06-01
MY158327A (en) 2016-09-30
AR071810A1 (es) 2010-07-14
EP2829280A1 (en) 2015-01-28
NZ598709A (en) 2013-09-27
US20120040902A1 (en) 2012-02-16
WO2009140659A3 (en) 2010-07-22
BRPI0913011A2 (pt) 2019-09-03
NZ701038A (en) 2016-01-29
EA201001771A1 (ru) 2011-06-30
GB2462221A (en) 2010-02-03
ES2546287T3 (es) 2015-09-22
MY159803A (en) 2017-02-15
US8415301B2 (en) 2013-04-09
JP5651586B2 (ja) 2015-01-14
CN103212063B (zh) 2015-07-22
SI2288373T1 (sl) 2015-12-31
US9066916B2 (en) 2015-06-30
JP2013040174A (ja) 2013-02-28
GB2459983B (en) 2010-04-28
HRP20150845T1 (hr) 2015-11-06
CA2724540A1 (en) 2009-11-19
CR11749A (es) 2011-02-11
EA201500552A1 (ru) 2016-07-29
WO2009140659A2 (en) 2009-11-19
GB2462221B (en) 2010-09-01
HK1202054A1 (en) 2015-09-18
GB0908432D0 (en) 2009-06-24
TWI386202B (zh) 2013-02-21
TW200948353A (en) 2009-12-01
JP5875646B2 (ja) 2016-03-02
US20120040903A1 (en) 2012-02-16
IL208992A (en) 2013-09-30
JP2011520918A (ja) 2011-07-21
CN102036679A (zh) 2011-04-27
HK1187550A1 (zh) 2014-04-11
ZA201007449B (en) 2011-06-29
IL228244A (en) 2016-10-31
US8053411B2 (en) 2011-11-08
EA022948B1 (ru) 2016-03-31
US9205132B2 (en) 2015-12-08
PT2288373E (pt) 2015-10-19
JP2016053040A (ja) 2016-04-14
HK1151229A1 (en) 2012-01-27
HK1139051A1 (en) 2010-09-10
HK1140693A1 (en) 2010-10-22
EP2288373A2 (en) 2011-03-02
UA99953C2 (uk) 2012-10-25
SG10201609580YA (en) 2016-12-29
IL208992A0 (en) 2011-01-31
HUE025483T2 (en) 2016-02-29
US20130210730A1 (en) 2013-08-15
CN103212063A (zh) 2013-07-24
AU2009246114B2 (en) 2013-01-31
GB0918132D0 (en) 2009-12-02
GB2459983A (en) 2009-11-18
US20130116181A1 (en) 2013-05-09
EP2288373B1 (en) 2015-06-24
JP5638044B2 (ja) 2014-12-10

Similar Documents

Publication Publication Date Title
HRP20150845T1 (hr) Relaksin za uporabu u lijeäśenju dispneje udružene s akutnim zatajanjem srca
IL230683A0 (en) dpp-iv inhibitors for use in the treatment of nafld
IL215975A (en) Heart failure device
BRPI0920498A2 (pt) método de tratamento de uma condição em um sujeito
HK1164112A1 (en) Treating hyperglycemia with glp-1 glp-1
EP2288366A4 (en) METHOD FOR TREATING CHRONIC HEART FAILURE
GB2475018B (en) Water treatment methods
HK1144157A1 (en) Treatment of water with hypobromite solution
IL207583A0 (en) Treating hyperglycemia with 25-hydroxyvitamin d3
IL200390A0 (en) Banana treatments
IL219565A0 (en) Method for treating heart failure with stresscopin-like peptides
IL207127A0 (en) Aldh-2 inhibitors in the treatment of addiction
HK1169993A1 (en) Hsl inhibitors useful in the treatment of diabetes hsl
PL2358214T3 (pl) Zastosowanie kantaksantyny i/lub 25-OH D3 dla poprawy wylęgowości u drobiu
EP2356038A4 (en) TRANSPORT AND TREATMENT OF WATER
GB0806047D0 (en) Treatment of heart failure
GB0821594D0 (en) Improvements in or relating to the treatment of tissue damage
ZA201206853B (en) Composition for use in water treatment
ZA201101773B (en) Compositions and methods for treating heart failure
GB0822435D0 (en) Method of treating chronic heart failure
GB0802458D0 (en) Improvements in or relating to medical treatments
PL386080A1 (pl) Zbiornik, zwłaszcza sanitarno-higieniczny do mycia i kąpieli
GB0816662D0 (en) Treatment of heart failure
GB0804320D0 (en) Treatment of heart failure
GB0800773D0 (en) Water treatment