CR10188A - Antagonistas de receptor de factor de crecimiento de tipo insulina (igf-ir) como auxiliares para tratamiento de cancer de prostata - Google Patents

Antagonistas de receptor de factor de crecimiento de tipo insulina (igf-ir) como auxiliares para tratamiento de cancer de prostata

Info

Publication number
CR10188A
CR10188A CR10188A CR10188A CR10188A CR 10188 A CR10188 A CR 10188A CR 10188 A CR10188 A CR 10188A CR 10188 A CR10188 A CR 10188A CR 10188 A CR10188 A CR 10188A
Authority
CR
Costa Rica
Prior art keywords
prostate cancer
igf
growth factor
assistants
cancer treatment
Prior art date
Application number
CR10188A
Other languages
English (en)
Inventor
Ludwig Dale
R Plymate Stephen
Original Assignee
Basf Se
Imclone Systems Inc
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se, Imclone Systems Inc, Univ Washington filed Critical Basf Se
Publication of CR10188A publication Critical patent/CR10188A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La presente invención se refiere a un método para tratar cáncer de próstata con terapia de privación de andrógeno y un antagonista de receptor de factor de crecimiento de tipo insulina (IGF-IR). Aunque la velocidad de respuesta de cáncer de próstata a la terapia de privación de andrógeno (ADT) es alta, las células de cáncer que sobreviven invariablemente se vuelven independientes de andrógeno (AI) y sigue el crecimiento del tumor. La invención inhibe o retrasa la transición de andrógeno, significativamente reduce el riesgo de recurrencia, y mejora el resultado del tratamiento.
CR10188A 2006-02-03 2008-08-01 Antagonistas de receptor de factor de crecimiento de tipo insulina (igf-ir) como auxiliares para tratamiento de cancer de prostata CR10188A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76507206P 2006-02-03 2006-02-03

Publications (1)

Publication Number Publication Date
CR10188A true CR10188A (es) 2008-11-18

Family

ID=38345750

Family Applications (1)

Application Number Title Priority Date Filing Date
CR10188A CR10188A (es) 2006-02-03 2008-08-01 Antagonistas de receptor de factor de crecimiento de tipo insulina (igf-ir) como auxiliares para tratamiento de cancer de prostata

Country Status (17)

Country Link
US (1) US7972600B2 (es)
EP (1) EP1984011A4 (es)
JP (1) JP5198289B2 (es)
KR (1) KR101353706B1 (es)
CN (1) CN101484587B (es)
AP (1) AP2008004569A0 (es)
AU (1) AU2007212447B2 (es)
CA (1) CA2641310C (es)
CR (1) CR10188A (es)
EA (1) EA017265B1 (es)
EC (1) ECSP088706A (es)
IL (1) IL193203A0 (es)
MX (1) MX2008009977A (es)
NO (1) NO20083444L (es)
UA (1) UA95945C2 (es)
WO (1) WO2007092453A2 (es)
ZA (1) ZA200807012B (es)

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Also Published As

Publication number Publication date
CN101484587B (zh) 2014-02-12
IL193203A0 (en) 2009-08-03
CN101484587A (zh) 2009-07-15
KR101353706B1 (ko) 2014-02-18
US7972600B2 (en) 2011-07-05
JP2009525348A (ja) 2009-07-09
UA95945C2 (ru) 2011-09-26
ECSP088706A (es) 2008-10-31
AU2007212447A1 (en) 2007-08-16
EP1984011A2 (en) 2008-10-29
NO20083444L (no) 2008-10-31
JP5198289B2 (ja) 2013-05-15
EA017265B1 (ru) 2012-11-30
ZA200807012B (en) 2009-12-30
US20090175868A1 (en) 2009-07-09
CA2641310A1 (en) 2007-08-16
EP1984011A4 (en) 2010-08-18
EA200870231A1 (ru) 2009-12-30
AP2008004569A0 (en) 2008-08-31
KR20080090566A (ko) 2008-10-08
WO2007092453A2 (en) 2007-08-16
AU2007212447B2 (en) 2013-02-21
CA2641310C (en) 2013-08-20
MX2008009977A (es) 2009-02-27
WO2007092453A3 (en) 2008-12-24

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