ATE90690T1 - Menschliche somatomedin-traeger-proteinuntereinheiten und verfahren zu ihrer herstellung. - Google Patents

Menschliche somatomedin-traeger-proteinuntereinheiten und verfahren zu ihrer herstellung.

Info

Publication number
ATE90690T1
ATE90690T1 AT88904042T AT88904042T ATE90690T1 AT E90690 T1 ATE90690 T1 AT E90690T1 AT 88904042 T AT88904042 T AT 88904042T AT 88904042 T AT88904042 T AT 88904042T AT E90690 T1 ATE90690 T1 AT E90690T1
Authority
AT
Austria
Prior art keywords
carrier protein
protein subunits
production
methods
human
Prior art date
Application number
AT88904042T
Other languages
English (en)
Inventor
Emerald Martin Spencer
Original Assignee
Celtrix Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celtrix Pharma filed Critical Celtrix Pharma
Application granted granted Critical
Publication of ATE90690T1 publication Critical patent/ATE90690T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4743Insulin-like growth factor binding protein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT88904042T 1987-04-06 1988-03-31 Menschliche somatomedin-traeger-proteinuntereinheiten und verfahren zu ihrer herstellung. ATE90690T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3488587A 1987-04-06 1987-04-06
PCT/US1988/001042 WO1988007863A1 (en) 1987-04-06 1988-03-31 Human somatomedin carrier protein subunits and process for producing them
EP88904042A EP0308500B1 (de) 1987-04-06 1988-03-31 Menschliche somatomedin-träger-protein-untereinheiten und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ATE90690T1 true ATE90690T1 (de) 1993-07-15

Family

ID=21879212

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88904042T ATE90690T1 (de) 1987-04-06 1988-03-31 Menschliche somatomedin-traeger-proteinuntereinheiten und verfahren zu ihrer herstellung.

Country Status (11)

Country Link
EP (2) EP0308500B1 (de)
JP (1) JP2648951B2 (de)
AT (1) ATE90690T1 (de)
AU (1) AU627423B2 (de)
CA (1) CA1340295C (de)
DE (1) DE3881801T2 (de)
DK (1) DK677688D0 (de)
ES (1) ES2058341T3 (de)
IL (1) IL85983A (de)
WO (1) WO1988007863A1 (de)
ZA (1) ZA882407B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5973115A (en) * 1987-05-15 1999-10-26 Amgen Inc. Method for potentiating and inhibiting insulin-like growth factor activity
US5258287A (en) * 1988-03-22 1993-11-02 Genentech, Inc. DNA encoding and methods of production of insulin-like growth factor binding protein BP53
AU1955388A (en) * 1988-04-12 1989-11-03 Synergen, Inc. Method for potentiating and inhibiting insulin-like growth factor activity
US5324820A (en) * 1988-07-15 1994-06-28 Central Sydney Area Health Service Acid-labile subunit (ALS) of insulin-like growth factor binding protein complex
EP0424416B1 (de) * 1988-07-15 1995-07-19 Central Sydney Area Health Service Säureempfindliche subeinheit eines insulinähnlichen wachstumfaktors-bindeprotein-komplexes
US6465423B1 (en) 1988-07-15 2002-10-15 Central Sydney Area Health Service Acid-labile subunit (ALS) of insulin-like growth factor binding protein complex
US5187151A (en) * 1991-02-12 1993-02-16 Genentech, Inc. Use of binding protein with igf-i as an anabolic growth promoting agent
RU2126683C1 (ru) * 1992-12-17 1999-02-27 Товарищество с ограниченной ответственностью "САМИ" Способ получения антисоматотропной сыворотки
CA2195474A1 (en) * 1994-07-20 1996-02-01 Cedo Martin Bagi Igf/igfbp complex for promoting bone formation and for regulating bone remodeling
US6420518B1 (en) 1997-04-04 2002-07-16 Genetech, Inc. Insulin-like growth factor agonist molecules
US6121416A (en) 1997-04-04 2000-09-19 Genentech, Inc. Insulin-like growth factor agonist molecules
PT1141014E (pt) 1999-01-06 2005-04-29 Genentech Inc Variante mutante do factor de crescimento semelhante a insulina (igf-i)
DE60042550D1 (de) 1999-01-06 2009-08-27 Genentech Inc Mutierte varianten des insulin-ähnlichen wachstumsfaktor i (igf-i)
ES2301547T3 (es) 2000-05-16 2008-07-01 Genentech, Inc. Tratamiento de trastornos del cartilago.
US7071300B2 (en) 2001-03-14 2006-07-04 Genentech, Inc. IGF antagonist peptides
WO2005016970A2 (en) 2003-05-01 2005-02-24 Imclone Systems Incorporated Fully human antibodies directed against the human insulin-like growth factor-1 receptor
ATE536186T1 (de) 2003-09-12 2011-12-15 Tercica Inc Verfahren zur behandlung von igf-1 (insulin-like growth factor 1)-mangel
EP1670822A2 (de) 2003-10-03 2006-06-21 Genentech, Inc. Igf-bindende proteine
PT2100618E (pt) 2005-06-17 2014-04-07 Philadelphia Health & Educatio Um anticorpo anti-pdgfr-alfa para o tratamento de cancro ósseo metastático
AU2007212447B2 (en) 2006-02-03 2013-02-21 Imclone Llc IGF-IR antagonists as adjuvants for treatment of prostate cancer
WO2019051474A1 (en) 2017-09-11 2019-03-14 Shire Human Genetic Therapies, Inc. METHODS AND COMPOSITIONS FOR TREATING CHRONIC PULMONARY DISEASES
JP7827315B2 (ja) 2020-10-19 2026-03-10 オーク ヒル バイオ リミテッド 新生児における使用に好適な組成物
AU2023210427A1 (en) 2022-01-19 2024-08-22 Oak Hill Bio Limited Compositions and methods for reducing oxidation of igf‐1/igfbp
WO2023242439A1 (en) 2022-06-17 2023-12-21 Oak Hill Bio Limited Vascular stabilisation (preterm infants)
WO2023242442A1 (en) 2022-06-17 2023-12-21 Oak Hill Bio Limited Method of maturing/differentiating neurons and/or modulating the vagus nerve
WO2023242440A1 (en) 2022-06-17 2023-12-21 Oak Hill Bio Limited Treament of lungs in infants
EP4665383A1 (de) 2023-02-14 2025-12-24 Oak Hill Bio Limited Behandlung von heilungsdysregulation in gi-gewebe

Also Published As

Publication number Publication date
ZA882407B (en) 1988-09-28
DE3881801T2 (de) 1993-12-23
IL85983A0 (en) 1988-09-30
AU627423B2 (en) 1992-08-27
EP0294021A1 (de) 1988-12-07
JP2648951B2 (ja) 1997-09-03
CA1340295C (en) 1998-12-29
DE3881801D1 (de) 1993-07-22
AU1702088A (en) 1988-11-04
DK677688A (da) 1988-12-05
EP0308500A1 (de) 1989-03-29
DK677688D0 (da) 1988-12-05
ES2058341T3 (es) 1994-11-01
JPH01502986A (ja) 1989-10-12
EP0308500B1 (de) 1993-06-16
WO1988007863A1 (en) 1988-10-20
IL85983A (en) 1994-10-07

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