CO6640266A2 - Proceso para preparar derivados de dihidropirrol - Google Patents

Proceso para preparar derivados de dihidropirrol

Info

Publication number
CO6640266A2
CO6640266A2 CO12223249A CO12223249A CO6640266A2 CO 6640266 A2 CO6640266 A2 CO 6640266A2 CO 12223249 A CO12223249 A CO 12223249A CO 12223249 A CO12223249 A CO 12223249A CO 6640266 A2 CO6640266 A2 CO 6640266A2
Authority
CO
Colombia
Prior art keywords
formula
compound
optionally substituted
naphthyl
phenyl
Prior art date
Application number
CO12223249A
Other languages
English (en)
Inventor
Qacemi Myriem El
Helmars Smit
Jerome Cassayre
Nicholas Phillip Mulholland
Peter Renold
Edouard Godineau
Thomas Pitterna
Original Assignee
Syngenta Participations Ag
Syngenta Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2010/058207 external-priority patent/WO2010149506A1/en
Application filed by Syngenta Participations Ag, Syngenta Ltd filed Critical Syngenta Participations Ag
Publication of CO6640266A2 publication Critical patent/CO6640266A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/46—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom rings with more than six members
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Zoology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención proporciona procesos estereoselectivos para preparar compuestos de fórmula (I)dondeP es fenilo, naftilo, un grupo heteroarilo de 6 miembros que contiene uno o dos átomos de nitrógeno como miembros anulares, o un grupo heteroarilo bicíclico de 10 miembros que contiene uno o dos átomos de nitrógeno como miembros anulares, y donde los grupos fenilo, naftilo y heteroarilo están opcionalmente sustituidos;R1 es clorodifluorometilo o trifluorometilo;R2 es arilo opcionalmente sustituido o heteroarilo opcionalmente sustituido;n es 001;incluido el proceso que comprende(a-i) hacer reaccionar un compuesto de fórmula IIdonde P, R1 y R2 son como se han definido para el compuesto de fórmula I; con nitrometano en presencia de un catalizador quiral para obtener un compuesto de fórmula IIIdonde P, R1 y R2 son como se han definido para el compuesto de fórmula I; y (a-ii) ciclar reductivamente el compuesto de fórmula III para obtener el compuesto de fórmula I.La invención también proporciona intermedios útiles para procesos para la síntesis de compuestos de fórmula (I).
CO12223249A 2010-06-11 2012-12-10 Proceso para preparar derivados de dihidropirrol CO6640266A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2010/058207 WO2010149506A1 (en) 2009-06-22 2010-06-11 Insecticidal compounds
EP10196633 2010-12-22

Publications (1)

Publication Number Publication Date
CO6640266A2 true CO6640266A2 (es) 2013-03-22

Family

ID=44627703

Family Applications (1)

Application Number Title Priority Date Filing Date
CO12223249A CO6640266A2 (es) 2010-06-11 2012-12-10 Proceso para preparar derivados de dihidropirrol

Country Status (14)

Country Link
US (1) US9233920B2 (es)
EP (1) EP2580211B1 (es)
JP (2) JP2013529594A (es)
KR (1) KR20130132726A (es)
CN (1) CN102939288B (es)
AU (1) AU2011263655B2 (es)
BR (1) BR112012031406A2 (es)
CA (1) CA2800114A1 (es)
CL (1) CL2012003491A1 (es)
CO (1) CO6640266A2 (es)
MX (1) MX2012014410A (es)
RU (1) RU2013100441A (es)
TW (1) TW201211057A (es)
WO (1) WO2011154555A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2013013211A (es) 2011-05-18 2014-02-20 Syngenta Participations Ag Compuestos insecticidas a base de derivados de ariltioacetamida.
MX2014002092A (es) 2011-08-25 2014-04-25 Syngenta Participations Ag Derivados de isoxazolina como compuestos insecticidas.
WO2013026929A1 (en) * 2011-08-25 2013-02-28 Syngenta Participations Ag Dihydropyrrole derivatives as insecticidal compounds
WO2013026930A1 (en) 2011-08-25 2013-02-28 Syngenta Participations Ag Process for the preparation of thietane derivatives
EP3896058A3 (en) * 2011-10-03 2022-01-12 Syngenta Participations Ag Enantionselective processes to insecticidal 3-aryl-3-trifluoromethyl-substituted pyrrolidines
CN109438316A (zh) 2011-10-03 2019-03-08 先正达参股股份有限公司 杀虫的3-芳基-3-三氟甲基-取代的吡咯烷的对映选择性方法
MX336431B (es) 2012-05-09 2016-01-18 Zoetis Services Llc Derivados de azetidina como agentes antiparasitarios.
BR112015002375A2 (pt) 2012-08-03 2017-07-04 Syngenta Participations Ag métodos de controle de insetos
CN103772233B (zh) * 2014-01-06 2015-06-10 华东师范大学 一种含多氟烷基五元环状硝酮衍生物及其制备方法
RU2019122791A (ru) * 2016-12-21 2021-01-25 Фмк Корпорейшн Гербициды на основе нитрона
GB201800894D0 (en) * 2018-01-19 2018-03-07 Syngenta Participations Ag Improvements in or relating to organic compounds
WO2024061178A1 (zh) * 2022-09-21 2024-03-28 青岛康乔药业集团有限公司 含五元杂环的化合物及其制备方法和应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US102011A (en) * 1870-04-19 Improvement in dovetailing-machine
US62009A (en) * 1867-02-12 Charles t
JP5007788B2 (ja) 2005-05-16 2012-08-22 日産化学工業株式会社 ジヒドロアゾール置換ベンズアミド化合物及び有害生物防除剤
AR059035A1 (es) 2006-01-16 2008-03-12 Syngenta Participations Ag Insecticidas derivados de antranilamida
DE102006015467A1 (de) 2006-03-31 2007-10-04 Bayer Cropscience Ag Substituierte Enaminocarbonylverbindungen
JP5164525B2 (ja) 2006-11-01 2013-03-21 日本曹達株式会社 含窒素へテロ環化合物および有害生物防除剤
EP2172448A4 (en) 2007-06-29 2012-01-11 Nissan Chemical Ind Ltd SUBSTITUTED ISOXAZOLINE OR ENONOXINE COMPOUND AND PESTICIDES
TWI556741B (zh) * 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
EP2230230A4 (en) * 2007-12-07 2011-03-16 Nissan Chemical Ind Ltd SUBSTITUTED DIHYDROAZOL COMPOUND AND PESTICIDES
TWI411395B (zh) 2007-12-24 2013-10-11 Syngenta Participations Ag 殺蟲化合物
AU2009211909A1 (en) * 2008-02-07 2009-08-13 Bayer Cropscience Ag Insecticidal arylpyrrolines
WO2010020522A1 (en) 2008-08-22 2010-02-25 Syngenta Participations Ag Insecticidal compounds
CN101519335A (zh) * 2009-04-10 2009-09-02 北京化工大学 一种提高多相不对称催化反应对映体选择性的方法
JP2010254629A (ja) 2009-04-27 2010-11-11 Bayer Cropscience Ag 光学活性アゾリン誘導体
ES2502340T3 (es) * 2009-06-22 2014-10-03 Syngenta Participations Ag Compuestos insecticidas
JP2011219431A (ja) * 2010-04-13 2011-11-04 Bayer Cropscience Ag 新規アリールニトロアルカン誘導体

Also Published As

Publication number Publication date
KR20130132726A (ko) 2013-12-05
US20130237583A1 (en) 2013-09-12
CN102939288A (zh) 2013-02-20
AU2011263655A1 (en) 2012-12-13
MX2012014410A (es) 2013-03-12
US9233920B2 (en) 2016-01-12
EP2580211A1 (en) 2013-04-17
CN102939288B (zh) 2015-09-30
CA2800114A1 (en) 2011-12-15
AU2011263655B2 (en) 2014-07-03
BR112012031406A2 (pt) 2015-09-22
JP2013529594A (ja) 2013-07-22
RU2013100441A (ru) 2014-07-20
WO2011154555A1 (en) 2011-12-15
JP2016210779A (ja) 2016-12-15
CL2012003491A1 (es) 2013-05-24
EP2580211B1 (en) 2015-08-19
TW201211057A (en) 2012-03-16

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