CO6612210A2 - Conjugados de dimeros de pirrolo(1.4) benzodiazepina como agentes anticancerosos - Google Patents

Conjugados de dimeros de pirrolo(1.4) benzodiazepina como agentes anticancerosos

Info

Publication number
CO6612210A2
CO6612210A2 CO12029986A CO12029986A CO6612210A2 CO 6612210 A2 CO6612210 A2 CO 6612210A2 CO 12029986 A CO12029986 A CO 12029986A CO 12029986 A CO12029986 A CO 12029986A CO 6612210 A2 CO6612210 A2 CO 6612210A2
Authority
CO
Colombia
Prior art keywords
conjugates
benzodiazepine
pyrrolo
dimeros
anticancer agents
Prior art date
Application number
CO12029986A
Other languages
English (en)
Inventor
Alain Commercon
Lazo Laurtence Gauzy
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of CO6612210A2 publication Critical patent/CO6612210A2/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/06—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00 containing at least one condensed beta-lactam ring system, provided for by groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00, e.g. a penem or a cepham system

Abstract

La presente invención se refiere a conjugados de dímeros de la pirrolo[1,4]benzodiazepina (PBD), composiciones que los contienen y procedimiento de preparación de los conjugados.
CO12029986A 2009-08-25 2012-02-21 Conjugados de dimeros de pirrolo(1.4) benzodiazepina como agentes anticancerosos CO6612210A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0904043A FR2949469A1 (fr) 2009-08-25 2009-08-25 Derives anticancereux, leur preparation et leur application en therapeutique
FR0904368A FR2949470B1 (fr) 2009-08-25 2009-09-11 Derives anticancereux, leur preparation et leur application therapeutique

Publications (1)

Publication Number Publication Date
CO6612210A2 true CO6612210A2 (es) 2013-02-01

Family

ID=41720559

Family Applications (1)

Application Number Title Priority Date Filing Date
CO12029986A CO6612210A2 (es) 2009-08-25 2012-02-21 Conjugados de dimeros de pirrolo(1.4) benzodiazepina como agentes anticancerosos

Country Status (33)

Country Link
US (2) US8481042B2 (es)
EP (1) EP2470547B1 (es)
JP (1) JP5889189B2 (es)
KR (1) KR20130026405A (es)
CN (1) CN102753559B (es)
AR (1) AR078143A1 (es)
AU (1) AU2010288382B2 (es)
BR (1) BR112012004146A2 (es)
CA (1) CA2772102C (es)
CL (2) CL2012000489A1 (es)
CO (1) CO6612210A2 (es)
CR (1) CR20120085A (es)
DO (1) DOP2012000038A (es)
EA (1) EA026488B1 (es)
EC (1) ECSP12011688A (es)
ES (1) ES2484690T3 (es)
FR (2) FR2949469A1 (es)
GT (1) GT201200046A (es)
HN (1) HN2012000437A (es)
IL (1) IL218262A0 (es)
MA (1) MA33600B1 (es)
MX (1) MX2012002434A (es)
MY (1) MY157469A (es)
NI (1) NI201200031A (es)
NZ (1) NZ598401A (es)
PE (1) PE20120992A1 (es)
SG (1) SG178537A1 (es)
TN (1) TN2012000053A1 (es)
TW (1) TWI477275B (es)
UA (1) UA106507C2 (es)
UY (1) UY32854A (es)
WO (1) WO2011023883A1 (es)
ZA (1) ZA201201397B (es)

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Also Published As

Publication number Publication date
EA201270308A1 (ru) 2013-01-30
CN102753559B (zh) 2015-11-25
MY157469A (en) 2016-06-15
NI201200031A (es) 2013-09-18
HN2012000437A (es) 2015-03-02
UY32854A (es) 2011-03-31
CR20120085A (es) 2012-06-01
AU2010288382A1 (en) 2012-03-15
US20140155590A1 (en) 2014-06-05
US8481042B2 (en) 2013-07-09
GT201200046A (es) 2014-09-26
CL2013001609A1 (es) 2013-11-04
TW201119657A (en) 2011-06-16
FR2949469A1 (fr) 2011-03-04
FR2949470B1 (fr) 2011-11-04
ZA201201397B (en) 2013-05-29
ECSP12011688A (es) 2012-03-30
EP2470547A1 (fr) 2012-07-04
ES2484690T3 (es) 2014-08-12
CL2012000489A1 (es) 2012-08-03
SG178537A1 (en) 2012-03-29
NZ598401A (en) 2014-03-28
PE20120992A1 (es) 2012-08-22
UA106507C2 (uk) 2014-09-10
CA2772102C (fr) 2018-09-04
EA026488B1 (ru) 2017-04-28
MA33600B1 (fr) 2012-09-01
EP2470547B1 (fr) 2014-05-14
IL218262A0 (en) 2012-04-30
WO2011023883A1 (fr) 2011-03-03
AR078143A1 (es) 2011-10-19
TN2012000053A1 (fr) 2013-09-19
JP5889189B2 (ja) 2016-03-22
CN102753559A (zh) 2012-10-24
US20120244172A1 (en) 2012-09-27
BR112012004146A2 (pt) 2017-05-30
MX2012002434A (es) 2012-07-20
AU2010288382B2 (en) 2015-10-22
DOP2012000038A (es) 2012-06-15
CA2772102A1 (fr) 2011-03-03
FR2949470A1 (fr) 2011-03-04
TWI477275B (zh) 2015-03-21
KR20130026405A (ko) 2013-03-13
JP2013503143A (ja) 2013-01-31

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