CO6361934A2 - Composicion farmaceutica solida - Google Patents

Composicion farmaceutica solida

Info

Publication number
CO6361934A2
CO6361934A2 CO11050084A CO11050084A CO6361934A2 CO 6361934 A2 CO6361934 A2 CO 6361934A2 CO 11050084 A CO11050084 A CO 11050084A CO 11050084 A CO11050084 A CO 11050084A CO 6361934 A2 CO6361934 A2 CO 6361934A2
Authority
CO
Colombia
Prior art keywords
pharmaceutical composition
solid pharmaceutical
compound
deprotonated
monocyclic
Prior art date
Application number
CO11050084A
Other languages
English (en)
Inventor
Kazuhiro Hirata
Junya Nomura
Yutaka Tanoue
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42059801&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO6361934(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of CO6361934A2 publication Critical patent/CO6361934A2/es

Links

Classifications

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    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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Abstract

La presente invención provee una preparación sólida que contiene el compuesto (I) representado por la fórmula (I)en donde R1 es un grupo heterocíclico, que comprende nitrógeno, monocíclico que tiene un átomo de hidrógeno que puede desprotonarse, R2 es un grupo carboxilo esterificado, y R3 es alquilo inferior opcionalmente sustituido, o su sal, un agente de control de pH y un antagonista de calcio, un método de estabilizar el compuesto (I) y un método de mejorar la disolución del mismo.
CO11050084A 2008-09-25 2011-04-25 Composicion farmaceutica solida CO6361934A2 (es)

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CA2738147A1 (en) 2010-04-01
WO2010035806A1 (ja) 2010-04-01
GEP20146063B (en) 2014-03-25
AU2009297522A1 (en) 2010-04-01
KR20110063557A (ko) 2011-06-10
CN102223884A (zh) 2011-10-19
NZ592225A (en) 2012-06-29
PE20110844A1 (es) 2011-12-05
CN102223884B (zh) 2015-05-06
EP2332535A1 (en) 2011-06-15
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CL2011000625A1 (es) 2011-07-08
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ZA201102715B (en) 2012-07-25
US20110229567A1 (en) 2011-09-22
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US9173849B2 (en) 2015-11-03
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MA32721B1 (fr) 2011-10-02
UY32126A (es) 2010-04-30
UA102271C2 (en) 2013-06-25
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