CO6140022A2 - Uso de una matriz hidrofila que comprende un derivado de acido poliacrilico un eter de celulosa y un desintegrante para la fabricacion de un medicamento para tratar trastornos genitales femeninos - Google Patents
Uso de una matriz hidrofila que comprende un derivado de acido poliacrilico un eter de celulosa y un desintegrante para la fabricacion de un medicamento para tratar trastornos genitales femeninosInfo
- Publication number
- CO6140022A2 CO6140022A2 CO08136879A CO08136879A CO6140022A2 CO 6140022 A2 CO6140022 A2 CO 6140022A2 CO 08136879 A CO08136879 A CO 08136879A CO 08136879 A CO08136879 A CO 08136879A CO 6140022 A2 CO6140022 A2 CO 6140022A2
- Authority
- CO
- Colombia
- Prior art keywords
- polyacrylic acid
- amounts
- acid derivative
- hydrophilic matrix
- disintegrant
- Prior art date
Links
- 239000011159 matrix material Substances 0.000 title abstract 11
- 229920002125 Sokalan® Polymers 0.000 title abstract 9
- 239000004584 polyacrylic acid Substances 0.000 title abstract 8
- 229920002678 cellulose Polymers 0.000 title abstract 3
- 239000001913 cellulose Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 208000017443 reproductive system disease Diseases 0.000 title abstract 2
- 229940126601 medicinal product Drugs 0.000 title 1
- 239000007884 disintegrant Substances 0.000 abstract 5
- 229920002472 Starch Polymers 0.000 abstract 3
- 229920003086 cellulose ether Polymers 0.000 abstract 3
- 235000019698 starch Nutrition 0.000 abstract 3
- 229920002785 Croscarmellose sodium Polymers 0.000 abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 229920000881 Modified starch Polymers 0.000 abstract 2
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 abstract 2
- 235000010980 cellulose Nutrition 0.000 abstract 2
- 239000001767 crosslinked sodium carboxy methyl cellulose Substances 0.000 abstract 2
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 abstract 2
- 235000019426 modified starch Nutrition 0.000 abstract 2
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 abstract 1
- 239000004382 Amylase Substances 0.000 abstract 1
- 102000013142 Amylases Human genes 0.000 abstract 1
- 108010065511 Amylases Proteins 0.000 abstract 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 abstract 1
- 229920002261 Corn starch Polymers 0.000 abstract 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 abstract 1
- 229920000148 Polycarbophil calcium Polymers 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 235000010443 alginic acid Nutrition 0.000 abstract 1
- 239000000783 alginic acid Substances 0.000 abstract 1
- 229920000615 alginic acid Polymers 0.000 abstract 1
- 229960001126 alginic acid Drugs 0.000 abstract 1
- 150000004781 alginic acids Chemical class 0.000 abstract 1
- 229920013820 alkyl cellulose Polymers 0.000 abstract 1
- 235000019418 amylase Nutrition 0.000 abstract 1
- 229960001631 carbomer Drugs 0.000 abstract 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 abstract 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 abstract 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 abstract 1
- 239000008120 corn starch Substances 0.000 abstract 1
- -1 crospovidone Chemical compound 0.000 abstract 1
- 229960000913 crospovidone Drugs 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 229920013821 hydroxy alkyl cellulose Polymers 0.000 abstract 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 abstract 1
- 239000008108 microcrystalline cellulose Substances 0.000 abstract 1
- 229940016286 microcrystalline cellulose Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229950005134 polycarbophil Drugs 0.000 abstract 1
- 235000013809 polyvinylpolypyrrolidone Nutrition 0.000 abstract 1
- 229920000523 polyvinylpolypyrrolidone Polymers 0.000 abstract 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1
- 229920001592 potato starch Polymers 0.000 abstract 1
- 229940069328 povidone Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 235000010413 sodium alginate Nutrition 0.000 abstract 1
- 239000000661 sodium alginate Substances 0.000 abstract 1
- 229940005550 sodium alginate Drugs 0.000 abstract 1
- 229920003109 sodium starch glycolate Polymers 0.000 abstract 1
- 239000008109 sodium starch glycolate Substances 0.000 abstract 1
- 229940079832 sodium starch glycolate Drugs 0.000 abstract 1
- 235000000346 sugar Nutrition 0.000 abstract 1
- 150000005846 sugar alcohols Polymers 0.000 abstract 1
- 150000008163 sugars Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Inorganic Chemistry (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06116269A EP1872775A1 (en) | 2006-06-29 | 2006-06-29 | Use of a hydrophilic matrix comprising a polyacrylic acid derivative, a cellulose ether and a disintegrant for the manufacture of a medicament for treating female genital disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO6140022A2 true CO6140022A2 (es) | 2010-03-19 |
Family
ID=37433668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO08136879A CO6140022A2 (es) | 2006-06-29 | 2008-12-24 | Uso de una matriz hidrofila que comprende un derivado de acido poliacrilico un eter de celulosa y un desintegrante para la fabricacion de un medicamento para tratar trastornos genitales femeninos |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US8865201B2 (enExample) |
| EP (2) | EP1872775A1 (enExample) |
| JP (1) | JP5205374B2 (enExample) |
| KR (1) | KR101443149B1 (enExample) |
| CN (2) | CN101478951A (enExample) |
| AR (1) | AR061771A1 (enExample) |
| AT (1) | ATE455534T1 (enExample) |
| BR (1) | BRPI0713298A2 (enExample) |
| CA (1) | CA2652226C (enExample) |
| CO (1) | CO6140022A2 (enExample) |
| CY (1) | CY1109910T1 (enExample) |
| DE (1) | DE602007004486D1 (enExample) |
| DK (1) | DK2032123T3 (enExample) |
| EA (1) | EA018257B1 (enExample) |
| ES (1) | ES2339069T3 (enExample) |
| HR (1) | HRP20100159T1 (enExample) |
| MA (1) | MA30597B1 (enExample) |
| MX (1) | MX2008016508A (enExample) |
| NO (1) | NO20090095L (enExample) |
| PL (1) | PL2032123T3 (enExample) |
| PT (1) | PT2032123E (enExample) |
| RS (1) | RS51279B (enExample) |
| SI (1) | SI2032123T1 (enExample) |
| WO (1) | WO2008000683A1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2344673B1 (es) | 2008-08-07 | 2011-05-03 | Italfarmaco, S.A. | Uso de estriol en la preparacion de una formulacion farmaceutica parael tratamiento de atrofia vaginal en mujeres con riesgo de potologiatumoral. |
| EP2163240A1 (en) * | 2008-09-12 | 2010-03-17 | Universita' Degli Studi Di Genova | A method for the production of bioadhesive compact matrices |
| RU2519715C2 (ru) * | 2008-10-23 | 2014-06-20 | Хенкель Корпорейшн | Фармацевтические гранулы, содержащие модифицированный крахмал, и их терапевтические применения |
| ES2344675B1 (es) * | 2008-12-19 | 2011-04-28 | Italfarmaco, S.A. | Uso de estriol en la preparacion de una formulacion farrmaceutica para el tratamiento de atrofia vaginal en mujeres con riesgo de patologiacardiovascular. |
| EP2243482A1 (en) * | 2009-04-20 | 2010-10-27 | Polichem SA | Use of nifuratel to treat infections caused by atopobium species |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| RS62297B1 (sr) | 2011-11-23 | 2021-09-30 | Therapeuticsmd Inc | Prirodne kombinovane hormonske supstitucione formulacije i terapije |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| BR112016009008B8 (pt) * | 2013-10-22 | 2023-01-31 | Therapeuticsmd Inc | Uso de estradiol e/ou hemi-hidrato de estradiol e de um agente solubilizante compreendendo um óleo de cadeia média para a preparação de um pessário para o tratamento de atrofia vulvovaginal e pessário que compreende estradiol |
| JP2017516768A (ja) | 2014-05-22 | 2017-06-22 | セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． | 天然の併用ホルモン補充療法剤及び療法 |
| CN105796520A (zh) * | 2014-12-29 | 2016-07-27 | 四川滇虹医药开发有限公司 | 一种缓释型硝酸布康唑直压片剂及其制备方法 |
| EP3247347B1 (en) | 2015-01-23 | 2025-01-08 | Biocidium IP Holdco, Co. | Anti-bacterial compositions |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| JP7219712B2 (ja) * | 2016-10-13 | 2023-02-08 | キャタレント・ユーケー・スウィンドン・ザイディス・リミテッド | 膣送達のための凍結乾燥医薬組成物 |
| GB201808567D0 (en) * | 2018-05-24 | 2018-07-11 | Douglas Pharmaceuticals Ltd | Pharmaceutical compositions |
| CN109010320B (zh) * | 2018-09-18 | 2021-09-14 | 浙江汇能生物股份有限公司 | 一种双释型聚卡波非钙颗粒剂及制备方法和畜禽中的应用 |
| MY208388A (en) * | 2019-04-05 | 2025-05-06 | Gedea Biotech Ab | Vaginal tablet formulation |
| CN114129530A (zh) * | 2021-12-08 | 2022-03-04 | 南京康川济医药科技有限公司 | 一种黄体酮缓释组合物及其制备方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2096744A (en) | 1932-10-27 | 1937-10-26 | Schering Corp | Hydrogenation products of follicle hormones and method of producing same |
| US2232438A (en) | 1934-08-04 | 1941-02-18 | Schering Corp | Unsaturated pregnanolones and pregnandiones and a method of producing the same |
| US2243887A (en) | 1935-11-09 | 1941-06-03 | Schering Corp | Tertiary carbinols of the cyclopentano-polyhydrophenanthrene series and a method of producing the same |
| US2251939A (en) | 1935-11-22 | 1941-08-12 | Schering Corp | Tertiary alcohols of the cyclopentano polyhydro phenanthrene series and a method of producing the same |
| US2379832A (en) | 1936-06-02 | 1945-07-03 | Schering Corp | Process for the manufacture of unsaturated ketones of the cyclopentano polyhydro phenanthrene series |
| CH202847A (de) | 1937-06-26 | 1939-02-15 | Chem Ind Basel | Verfahren zur Darstellung von Acetylen-Derivaten der Cyclopentanopolyhydrophenanthren-Reihe. |
| US2265976A (en) | 1937-10-25 | 1941-12-09 | Schering Corp | Tertiary alcohols of the estrane series and their derivatives and a process for their manufacture |
| US2314185A (en) | 1939-09-01 | 1943-03-16 | Zondek Bernhard | Process for the manufacture of progesterone |
| BE665514A (enExample) | 1964-06-16 | |||
| NL146838B (nl) | 1966-06-24 | 1975-08-15 | Organon Nv | Werkwijze voor het bereiden van (delta)5(10)-3- keto-19-norsteroiden. |
| JPS5562012A (en) * | 1978-11-06 | 1980-05-10 | Teijin Ltd | Slow-releasing preparation |
| US7744916B2 (en) * | 1997-06-11 | 2010-06-29 | Umd, Inc. | Coated vaginal device for delivery of anti-migraine and anti-nausea drugs |
| US6416779B1 (en) * | 1997-06-11 | 2002-07-09 | Umd, Inc. | Device and method for intravaginal or transvaginal treatment of fungal, bacterial, viral or parasitic infections |
| US6248358B1 (en) | 1998-08-25 | 2001-06-19 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets and methods of making and using the same |
| UA74168C2 (uk) | 1999-10-05 | 2005-11-15 | Коламбіа Леборетеріс (Бермуда) Лімітед | Лікування ендометріозу або безпліддя, або покращення плідності та застосування бета-адренергічного агоніста для виробництва лікарського засобу |
| AU2001268722B8 (en) * | 2000-06-23 | 2005-09-29 | Teva Pharmaceutical Industries Ltd. | Rapidly expanding composition for gastric retention and controlled release of therapeutic agents, and dosage forms including the composition |
| FR2813865B1 (fr) | 2000-09-08 | 2002-12-20 | Rexam Sofab | Dispositif a buse unique pour la distribution selective de deux produits |
| AU7384700A (en) * | 2000-09-19 | 2002-04-02 | Cima Labs Inc | Pharmaceutical compositions for rectal and vaginal administration |
| NZ528377A (en) * | 2001-03-27 | 2005-05-27 | Galen Chemicals Ltd | Intravaginal drug delivery devices for the administration of an antimicrobial agent |
| US6899890B2 (en) * | 2002-03-20 | 2005-05-31 | Kv Pharmaceutical Company | Bioadhesive drug delivery system |
| CN1302764C (zh) | 2005-01-10 | 2007-03-07 | 凌沛学 | 一种妇科用药阴道凝胶片 |
-
2006
- 2006-06-29 EP EP06116269A patent/EP1872775A1/en not_active Withdrawn
-
2007
- 2007-06-21 CA CA2652226A patent/CA2652226C/en not_active Expired - Fee Related
- 2007-06-21 EA EA200900087A patent/EA018257B1/ru not_active IP Right Cessation
- 2007-06-21 KR KR1020087032076A patent/KR101443149B1/ko not_active Expired - Fee Related
- 2007-06-21 EP EP07730288A patent/EP2032123B1/en active Active
- 2007-06-21 JP JP2009517127A patent/JP5205374B2/ja not_active Expired - Fee Related
- 2007-06-21 BR BRPI0713298-0A patent/BRPI0713298A2/pt not_active IP Right Cessation
- 2007-06-21 MX MX2008016508A patent/MX2008016508A/es active IP Right Grant
- 2007-06-21 ES ES07730288T patent/ES2339069T3/es active Active
- 2007-06-21 SI SI200730193T patent/SI2032123T1/sl unknown
- 2007-06-21 CN CNA2007800239858A patent/CN101478951A/zh active Pending
- 2007-06-21 PT PT07730288T patent/PT2032123E/pt unknown
- 2007-06-21 WO PCT/EP2007/056185 patent/WO2008000683A1/en not_active Ceased
- 2007-06-21 CN CN2013100083584A patent/CN103071157A/zh active Pending
- 2007-06-21 DE DE602007004486T patent/DE602007004486D1/de active Active
- 2007-06-21 AT AT07730288T patent/ATE455534T1/de active
- 2007-06-21 HR HR20100159T patent/HRP20100159T1/hr unknown
- 2007-06-21 PL PL07730288T patent/PL2032123T3/pl unknown
- 2007-06-21 RS RSP-2010/0045A patent/RS51279B/sr unknown
- 2007-06-21 DK DK07730288.3T patent/DK2032123T3/da active
- 2007-06-21 US US12/308,786 patent/US8865201B2/en not_active Expired - Fee Related
- 2007-06-29 AR ARP070102948A patent/AR061771A1/es unknown
-
2008
- 2008-12-24 CO CO08136879A patent/CO6140022A2/es unknown
-
2009
- 2009-01-07 NO NO20090095A patent/NO20090095L/no not_active Application Discontinuation
- 2009-01-22 MA MA31583A patent/MA30597B1/fr unknown
-
2010
- 2010-03-19 CY CY20101100256T patent/CY1109910T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY1109910T1 (el) | 2014-09-10 |
| US8865201B2 (en) | 2014-10-21 |
| ATE455534T1 (de) | 2010-02-15 |
| CA2652226A1 (en) | 2008-01-03 |
| BRPI0713298A2 (pt) | 2012-04-17 |
| AR061771A1 (es) | 2008-09-17 |
| EP2032123A1 (en) | 2009-03-11 |
| CA2652226C (en) | 2014-08-12 |
| SI2032123T1 (sl) | 2010-04-30 |
| CN101478951A (zh) | 2009-07-08 |
| RS51279B (sr) | 2010-12-31 |
| MX2008016508A (es) | 2009-04-22 |
| ES2339069T3 (es) | 2010-05-14 |
| EP2032123B1 (en) | 2010-01-20 |
| JP5205374B2 (ja) | 2013-06-05 |
| KR101443149B1 (ko) | 2014-09-23 |
| US20110091555A1 (en) | 2011-04-21 |
| DE602007004486D1 (de) | 2010-03-11 |
| JP2009541419A (ja) | 2009-11-26 |
| PL2032123T3 (pl) | 2010-06-30 |
| WO2008000683A1 (en) | 2008-01-03 |
| EP1872775A1 (en) | 2008-01-02 |
| CN103071157A (zh) | 2013-05-01 |
| MA30597B1 (fr) | 2009-07-01 |
| HK1128587A1 (en) | 2009-10-30 |
| EA200900087A1 (ru) | 2009-06-30 |
| HRP20100159T1 (hr) | 2010-05-31 |
| KR20090033341A (ko) | 2009-04-02 |
| NO20090095L (no) | 2009-01-07 |
| PT2032123E (pt) | 2010-04-07 |
| DK2032123T3 (da) | 2010-03-08 |
| EA018257B1 (ru) | 2013-06-28 |
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