CO5670359A2 - Preparacion y tratamiento para las enfermedades desmielinizantes y paralisis mediante la aplicacion de agentes remielinizantes - Google Patents
Preparacion y tratamiento para las enfermedades desmielinizantes y paralisis mediante la aplicacion de agentes remielinizantesInfo
- Publication number
- CO5670359A2 CO5670359A2 CO05084319A CO05084319A CO5670359A2 CO 5670359 A2 CO5670359 A2 CO 5670359A2 CO 05084319 A CO05084319 A CO 05084319A CO 05084319 A CO05084319 A CO 05084319A CO 5670359 A2 CO5670359 A2 CO 5670359A2
- Authority
- CO
- Colombia
- Prior art keywords
- demyelination
- condition
- preparation
- treatment
- induced
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 206010033799 Paralysis Diseases 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000016192 Demyelinating disease Diseases 0.000 abstract 6
- 206010012305 Demyelination Diseases 0.000 abstract 6
- 241000124008 Mammalia Species 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 201000006417 multiple sclerosis Diseases 0.000 abstract 2
- 102000029797 Prion Human genes 0.000 abstract 1
- 108091000054 Prion Proteins 0.000 abstract 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 206010014599 encephalitis Diseases 0.000 abstract 1
- 208000016245 inborn errors of metabolism Diseases 0.000 abstract 1
- 230000023105 myelination Effects 0.000 abstract 1
- 210000002569 neuron Anatomy 0.000 abstract 1
- 201000001119 neuropathy Diseases 0.000 abstract 1
- 230000007823 neuropathy Effects 0.000 abstract 1
- 208000033808 peripheral neuropathy Diseases 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
- 210000000278 spinal cord Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Gastroenterology & Hepatology (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44217103P | 2003-01-24 | 2003-01-24 | |
| US50031603P | 2003-09-05 | 2003-09-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5670359A2 true CO5670359A2 (es) | 2006-08-31 |
Family
ID=32829779
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO05084319A CO5670359A2 (es) | 2003-01-24 | 2005-08-24 | Preparacion y tratamiento para las enfermedades desmielinizantes y paralisis mediante la aplicacion de agentes remielinizantes |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US7576101B2 (https=) |
| EP (4) | EP3527228A1 (https=) |
| JP (4) | JP2007521249A (https=) |
| KR (2) | KR101260497B1 (https=) |
| AU (5) | AU2004207536B2 (https=) |
| CA (2) | CA2514117A1 (https=) |
| CO (1) | CO5670359A2 (https=) |
| IL (1) | IL169770A (https=) |
| MX (2) | MXPA05007823A (https=) |
| NO (1) | NO20053920L (https=) |
| PE (1) | PE20040942A1 (https=) |
| RU (1) | RU2412721C2 (https=) |
| SK (1) | SK50642005A3 (https=) |
| TW (2) | TWI428141B (https=) |
| UY (1) | UY28170A1 (https=) |
| WO (2) | WO2004066932A2 (https=) |
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|---|---|---|---|---|
| US7368421B2 (en) | 2001-06-27 | 2008-05-06 | Probiodrug Ag | Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis |
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| US7794700B2 (en) | 2004-07-08 | 2010-09-14 | Elan Pharmaceuticals Inc. | Multimeric VLA-4 antagonists comprising polymer moieties |
| CA2478458A1 (en) * | 2004-08-20 | 2006-02-20 | Michael Panzara | Treatment of pediatric multiple sclerosis |
| CA2587597A1 (en) * | 2004-11-19 | 2006-05-26 | Biogen Idec Ma Inc. | Treatment for multiple sclerosis |
| NZ581497A (en) * | 2004-12-03 | 2012-07-27 | Biogen Idec Inc | Delaying or preventing onset of multiple sclerosis by vla-4 ginding antibody |
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| EP2198040B1 (en) * | 2007-08-31 | 2018-08-15 | Case Western Reserve University | In vivo imaging of myelin |
| EP2344479B1 (en) * | 2008-09-23 | 2015-04-08 | Georgetown University | 1,2-benzisothiazolinone and isoindolinone derivatives |
| JP2013525260A (ja) * | 2009-04-17 | 2013-06-20 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 急性骨髄性白血病を治療するための組成物および方法 |
| EP2467159A1 (en) * | 2009-08-20 | 2012-06-27 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Vla-4 as a biomarker for prognosis and target for therapy in duchenne muscular dystrophy |
| HRP20171045T1 (hr) | 2010-04-16 | 2017-10-06 | Biogen Ma Inc. | Protutijela anti-vla-4 |
| EP2588112B1 (en) * | 2010-06-30 | 2017-09-27 | Victoria Link Ltd | Methods and compositions for treatment of multiple sclerosis |
| EP3326645B1 (en) | 2010-10-25 | 2020-03-18 | Biogen MA Inc. | Methods for determining differences in alpha-4 integrin activity by correlating differences in svcam and/or smadcam levels |
| SG191716A1 (en) | 2010-11-19 | 2013-08-30 | Toshio Imai | Neutralizing anti-ccl20 antibodies |
| WO2013025897A1 (en) | 2011-08-16 | 2013-02-21 | Georgetown University | Methods of treating bacterial infections with 1,2-benzisothiazolinone and isoindolinone derivatives |
| CN107551269A (zh) | 2012-02-29 | 2018-01-09 | 百深公司 | 周围神经的IgG刺激髓鞘再生 |
| TWI595007B (zh) | 2012-09-10 | 2017-08-11 | Neotope Biosciences Ltd | 抗ｍｃａｍ抗體及相關使用方法 |
| CA2887682A1 (en) * | 2012-10-09 | 2014-04-17 | Biogen Idec Ma Inc. | Combination therapies and uses for treatment of demyelinating disorders |
| WO2015048819A1 (en) | 2013-09-30 | 2015-04-02 | The Regents Of The University Of California | Anti-alphavbeta1 integrin compounds and methods |
| JP2017514458A (ja) | 2014-03-12 | 2017-06-08 | プロセナ バイオサイエンシーズ リミテッド | Ｌｇ４−５に対して特異的な抗−ラミニン４抗体 |
| PT3116911T (pt) | 2014-03-12 | 2019-09-04 | Prothena Biosciences Ltd | Anticorpos anti-mcam e métodos de utilização associados |
| KR20170052526A (ko) * | 2014-03-13 | 2017-05-12 | 프로테나 바이오사이언시즈 리미티드 | 다발성 경화증에 대한 병용 치료 |
| KR102364840B1 (ko) | 2014-11-05 | 2022-02-18 | 삼성전자주식회사 | 신경세포의 탈수초화와 연관된 질환을 치료하기 위한 약학적 조성물 및 그를 이용하는 방법 |
| US20170348375A1 (en) * | 2014-12-12 | 2017-12-07 | Commonwealth Scientific And Industrial Research Organisation | Dislodgement and release of hsc from the bone marrow stem cell niche using alpha9 integrin antagonists |
| US10738121B2 (en) | 2015-02-27 | 2020-08-11 | The General Hospital Corporation | Therapeutic use of integrin-binding antibodies |
| WO2016145258A1 (en) | 2015-03-10 | 2016-09-15 | The Regents Of The University Of California | Anti-alphavbeta1 integrin inhibitors and methods of use |
| CN106316982B (zh) | 2015-06-30 | 2020-08-14 | 中国人民解放军军事医学科学院毒物药物研究所 | 噻嗪酰胺衍生物及其用途 |
| US10947311B2 (en) * | 2015-11-20 | 2021-03-16 | The Board Of Trustees Of The Leland Stanford Junior University | VCAM-1 mediated methods and compositions for treating aging-associated impairments |
| AU2019274649B2 (en) * | 2018-05-23 | 2025-10-09 | Csl Behring Ag | Treatment of CIDP |
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| ES3013256T3 (en) | 2018-10-30 | 2025-04-11 | Gilead Sciences Inc | Imidazo[1,2-a]pyridine derivatives as alpha4beta7 integrin inhibitors for the treatment of inflammatory diseases |
| JP7189368B2 (ja) | 2018-10-30 | 2022-12-13 | ギリアード サイエンシーズ， インコーポレイテッド | アルファ４ベータ７インテグリンの阻害のための化合物 |
| EP3873605B1 (en) | 2018-10-30 | 2024-10-23 | Gilead Sciences, Inc. | Compounds for inhibition of alpha4beta7 integrin |
| FI3873884T3 (fi) | 2018-10-30 | 2025-02-24 | Gilead Sciences Inc | 3-(kinolin-8-yyli)-1,4-dihydropyrido[3,4-d]pyrimidiini-2,4-dionijohdannaisia alfa-4-beta-7-integriinin estäjinä tulehdussairauksien hoidossa |
| WO2021030438A1 (en) | 2019-08-14 | 2021-02-18 | Gilead Sciences, Inc. | Compounds for inhibition of alpha 4 beta 7 integrin |
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2004
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- 2004-01-26 AU AU2004207536A patent/AU2004207536B2/en not_active Expired - Fee Related
- 2004-01-26 US US10/763,539 patent/US7576101B2/en active Active
- 2004-01-26 MX MXPA05007823A patent/MXPA05007823A/es not_active Application Discontinuation
- 2004-01-26 WO PCT/US2004/002039 patent/WO2004066932A2/en not_active Ceased
- 2004-01-26 PE PE2004000100A patent/PE20040942A1/es not_active Application Discontinuation
- 2004-01-26 EP EP19152970.0A patent/EP3527228A1/en not_active Withdrawn
- 2004-01-26 EP EP04705266A patent/EP1592386A4/en not_active Withdrawn
- 2004-01-26 KR KR1020127024847A patent/KR101260497B1/ko not_active Expired - Lifetime
- 2004-01-26 WO PCT/US2004/002028 patent/WO2004066931A2/en not_active Ceased
- 2004-01-26 CA CA002514125A patent/CA2514125A1/en not_active Abandoned
- 2004-01-26 MX MXPA05007843A patent/MXPA05007843A/es unknown
- 2004-01-26 JP JP2006503001A patent/JP2007521249A/ja active Pending
- 2004-01-26 SK SK5064-2005A patent/SK50642005A3/sk not_active Application Discontinuation
- 2004-01-26 EP EP11008463A patent/EP2484381A1/en not_active Withdrawn
- 2004-01-26 RU RU2005126728/15A patent/RU2412721C2/ru active
- 2004-01-26 US US10/763,424 patent/US20050069541A1/en not_active Abandoned
- 2004-01-26 EP EP04705270A patent/EP1592387A4/en not_active Withdrawn
- 2004-01-26 AU AU2004207535A patent/AU2004207535A1/en not_active Abandoned
- 2004-01-26 JP JP2006502997A patent/JP2006516624A/ja active Pending
- 2004-01-26 KR KR1020057013695A patent/KR20050114212A/ko not_active Ceased
- 2004-01-26 UY UY28170A patent/UY28170A1/es not_active Application Discontinuation
- 2004-01-27 TW TW093101747A patent/TWI428141B/zh not_active IP Right Cessation
- 2004-01-27 TW TW101146999A patent/TW201311238A/zh unknown
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2005
- 2005-07-19 IL IL169770A patent/IL169770A/en active IP Right Grant
- 2005-08-23 NO NO20053920A patent/NO20053920L/no not_active Application Discontinuation
- 2005-08-24 CO CO05084319A patent/CO5670359A2/es not_active Application Discontinuation
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2010
- 2010-04-14 AU AU2010201472A patent/AU2010201472A1/en not_active Abandoned
- 2010-08-19 AU AU2010212446A patent/AU2010212446B2/en not_active Expired
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2011
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