CO5080739A1 - Compuestos antibacterianos de cefalosporinas de 7-acilamino- 3-(amino-guanidina ciclica) metileno utiles como productos farmaceuticos y procesos para su produccion - Google Patents
Compuestos antibacterianos de cefalosporinas de 7-acilamino- 3-(amino-guanidina ciclica) metileno utiles como productos farmaceuticos y procesos para su produccionInfo
- Publication number
- CO5080739A1 CO5080739A1 CO99017143A CO99017143A CO5080739A1 CO 5080739 A1 CO5080739 A1 CO 5080739A1 CO 99017143 A CO99017143 A CO 99017143A CO 99017143 A CO99017143 A CO 99017143A CO 5080739 A1 CO5080739 A1 CO 5080739A1
- Authority
- CO
- Colombia
- Prior art keywords
- acilamino
- cephalosporins
- methylene
- amino
- useful
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 title 2
- 229930186147 Cephalosporin Natural products 0.000 title 1
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 title 1
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 229940124587 cephalosporin Drugs 0.000 title 1
- HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 title 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 title 1
- HZVOZRGWRWCICA-UHFFFAOYSA-N methanediyl Chemical class [CH2] HZVOZRGWRWCICA-UHFFFAOYSA-N 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 229940127557 pharmaceutical product Drugs 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0051598A AT406772B (de) | 1998-03-23 | 1998-03-23 | Antibakterielle 7-acylamino-3-iminomethyl- cephalosporine und verfahren zu deren herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5080739A1 true CO5080739A1 (es) | 2001-09-25 |
Family
ID=3492649
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO99017143A CO5080739A1 (es) | 1998-03-23 | 1999-03-19 | Compuestos antibacterianos de cefalosporinas de 7-acilamino- 3-(amino-guanidina ciclica) metileno utiles como productos farmaceuticos y procesos para su produccion |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US6440957B1 (https=) |
| EP (2) | EP1082326A1 (https=) |
| JP (1) | JP2002507616A (https=) |
| KR (1) | KR100696422B1 (https=) |
| CN (1) | CN1188418C (https=) |
| AR (1) | AR015248A1 (https=) |
| AT (1) | AT406772B (https=) |
| AU (1) | AU749735B2 (https=) |
| BR (1) | BR9908960A (https=) |
| CA (1) | CA2324953C (https=) |
| CO (1) | CO5080739A1 (https=) |
| HU (1) | HUP0101603A3 (https=) |
| ID (1) | ID26567A (https=) |
| IL (2) | IL138477A0 (https=) |
| MY (1) | MY119841A (https=) |
| NO (1) | NO20004760L (https=) |
| NZ (1) | NZ506908A (https=) |
| PE (1) | PE20000360A1 (https=) |
| PL (1) | PL343094A1 (https=) |
| RU (1) | RU2245884C2 (https=) |
| SK (1) | SK14152000A3 (https=) |
| TR (1) | TR200002749T2 (https=) |
| TW (1) | TWI250983B (https=) |
| WO (1) | WO1999048896A1 (https=) |
| ZA (1) | ZA200004850B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020115852A1 (en) * | 1997-04-01 | 2002-08-22 | Gerd Ascher | Antibacterial substituted 7-acylamino-3-(methylhydrazono) methyl-cephalosporins and intermediates |
| DE102007052891A1 (de) | 2007-11-02 | 2009-05-07 | Evonik Degussa Gmbh | Verfahren zur Stabilisierung von olefinisch ungesättigten Monomeren |
| DE102013204950A1 (de) | 2013-03-20 | 2014-09-25 | Evonik Industries Ag | Verfahren und Zusammensetzung zur Inhibierung der Polymerisation von Cyclopentadienverbindungen |
| EP2993164B1 (de) | 2014-09-08 | 2017-02-15 | Evonik Degussa GmbH | Phenolische (Thio)Acetale als Inhibitoren der Polymerisation von olefinisch ungesättigten Monomeren |
| TWI669317B (zh) | 2014-09-22 | 2019-08-21 | 德商贏創德固賽有限責任公司 | 反應性單體的改良製造方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE943408C (de) * | 1953-03-31 | 1956-05-17 | Bayer Ag | Verfahren zur Darstellung von Bisguanylhydrazonen |
| FI851934A7 (fi) * | 1984-05-30 | 1985-12-01 | Ici Plc | Kefalosporiinijohdannaisia. |
| GB8721568D0 (en) * | 1987-09-14 | 1987-10-21 | Fujisawa Pharmaceutical Co | Cephem compounds |
| RU2183212C2 (ru) * | 1995-05-11 | 2002-06-10 | Биохеми Гезельшафт Мбх | Антибактериальные цефалоспорины, фармацевтическая композиция на их основе и способ лечения |
| CN1117095C (zh) * | 1997-04-01 | 2003-08-06 | 生物化学有限公司 | 具有抗菌作用的取代的7－酰氨基－3－(甲基亚肼基)甲基头孢菌素和中间体 |
-
1998
- 1998-03-23 AT AT0051598A patent/AT406772B/de not_active IP Right Cessation
-
1999
- 1999-03-19 KR KR1020007010434A patent/KR100696422B1/ko not_active Expired - Fee Related
- 1999-03-19 EP EP99916839A patent/EP1082326A1/en not_active Withdrawn
- 1999-03-19 TR TR2000/02749T patent/TR200002749T2/xx unknown
- 1999-03-19 HU HU0101603A patent/HUP0101603A3/hu unknown
- 1999-03-19 RU RU2000126469/04A patent/RU2245884C2/ru not_active IP Right Cessation
- 1999-03-19 SK SK1415-2000A patent/SK14152000A3/sk unknown
- 1999-03-19 ID IDW20001853A patent/ID26567A/id unknown
- 1999-03-19 CN CNB998043192A patent/CN1188418C/zh not_active Expired - Fee Related
- 1999-03-19 CO CO99017143A patent/CO5080739A1/es unknown
- 1999-03-19 WO PCT/EP1999/001853 patent/WO1999048896A1/en not_active Ceased
- 1999-03-19 JP JP2000537879A patent/JP2002507616A/ja not_active Withdrawn
- 1999-03-19 CA CA002324953A patent/CA2324953C/en not_active Expired - Fee Related
- 1999-03-19 NZ NZ506908A patent/NZ506908A/xx unknown
- 1999-03-19 ZA ZA200004850A patent/ZA200004850B/en unknown
- 1999-03-19 IL IL13847799A patent/IL138477A0/xx not_active IP Right Cessation
- 1999-03-19 AU AU35188/99A patent/AU749735B2/en not_active Ceased
- 1999-03-19 AR ARP990101236A patent/AR015248A1/es not_active Application Discontinuation
- 1999-03-19 PL PL99343094A patent/PL343094A1/xx unknown
- 1999-03-19 BR BR9908960-2A patent/BR9908960A/pt not_active Application Discontinuation
- 1999-03-19 EP EP07021394A patent/EP1930335A1/en not_active Withdrawn
- 1999-03-22 PE PE1999000232A patent/PE20000360A1/es not_active Application Discontinuation
- 1999-03-22 MY MYPI99001068A patent/MY119841A/en unknown
- 1999-05-10 TW TW088107541A patent/TWI250983B/zh not_active IP Right Cessation
-
2000
- 2000-09-14 IL IL138477A patent/IL138477A/en unknown
- 2000-09-21 US US09/667,075 patent/US6440957B1/en not_active Expired - Fee Related
- 2000-09-22 NO NO20004760A patent/NO20004760L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| TR200002749T2 (tr) | 2000-12-21 |
| IL138477A (en) | 2007-06-17 |
| NZ506908A (en) | 2003-04-29 |
| ATA51598A (de) | 2000-01-15 |
| CA2324953C (en) | 2008-05-13 |
| PL343094A1 (en) | 2001-07-30 |
| CN1294593A (zh) | 2001-05-09 |
| HUP0101603A3 (en) | 2002-10-28 |
| EP1930335A1 (en) | 2008-06-11 |
| TWI250983B (en) | 2006-03-11 |
| JP2002507616A (ja) | 2002-03-12 |
| AU749735B2 (en) | 2002-07-04 |
| IL138477A0 (en) | 2001-10-31 |
| EP1082326A1 (en) | 2001-03-14 |
| US6440957B1 (en) | 2002-08-27 |
| PE20000360A1 (es) | 2000-05-17 |
| ID26567A (id) | 2001-01-18 |
| WO1999048896A1 (en) | 1999-09-30 |
| HUP0101603A2 (hu) | 2001-12-28 |
| KR100696422B1 (ko) | 2007-03-20 |
| NO20004760L (no) | 2000-11-21 |
| AR015248A1 (es) | 2001-04-18 |
| CA2324953A1 (en) | 1999-09-30 |
| CN1188418C (zh) | 2005-02-09 |
| AU3518899A (en) | 1999-10-18 |
| NO20004760D0 (no) | 2000-09-22 |
| KR20010074666A (ko) | 2001-08-08 |
| BR9908960A (pt) | 2000-12-05 |
| MY119841A (en) | 2005-07-29 |
| SK14152000A3 (sk) | 2001-05-10 |
| RU2245884C2 (ru) | 2005-02-10 |
| ZA200004850B (en) | 2002-02-27 |
| AT406772B (de) | 2000-08-25 |
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