CO4940487A1 - Compuestos de fungarrestina, procesos para producirlos y medicamentos para el tratamiento de tumores - Google Patents
Compuestos de fungarrestina, procesos para producirlos y medicamentos para el tratamiento de tumoresInfo
- Publication number
- CO4940487A1 CO4940487A1 CO97031203A CO97031203A CO4940487A1 CO 4940487 A1 CO4940487 A1 CO 4940487A1 CO 97031203 A CO97031203 A CO 97031203A CO 97031203 A CO97031203 A CO 97031203A CO 4940487 A1 CO4940487 A1 CO 4940487A1
- Authority
- CO
- Colombia
- Prior art keywords
- dsm
- fungarrestine
- medicines
- tumors
- compounds
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 241001225321 Aspergillus fumigatus Species 0.000 abstract 5
- 229940091771 aspergillus fumigatus Drugs 0.000 abstract 5
- 241001480052 Aspergillus japonicus Species 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/16—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D267/20—[b, f]-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
- C07D321/02—Seven-membered rings
- C07D321/10—Seven-membered rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/08—Oxygen as only ring hetero atoms containing a hetero ring of at least seven ring members, e.g. zearalenone, macrolide aglycons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/14—Nitrogen or oxygen as hetero atom and at least one other diverse hetero ring atom in the same ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Motorcycle And Bicycle Frame (AREA)
- Rehabilitation Tools (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Fungarrestinas de fórmula general (I) donde R1 y R2 son cada uno, hidrógeno, grupos hidrocarbonados que contienen hasta 6 átomos de carbono inclusive o acilo; X es CO ó CHOH; Y es CO ó CH2 ; y Z es O ó NH, y las sales de las mismas fisiológicamente utilizables.Aspergillus japonicus NR 7328 (DSM 10677), Aspergillus fumigatus NR 7329 (DSM 10678), Aspergillus fumigatus NR 7330 (DSM 10679), Aspergillus fumigatus NR 7330 (DSM 10680), Aspergillus fumigatus NR 7332 (DSM 10681 y Aspergillus fumigatus NR 7334 (DSM 10682).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96109115 | 1996-06-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO4940487A1 true CO4940487A1 (es) | 2000-07-24 |
Family
ID=8222857
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO97031203A CO4940487A1 (es) | 1996-06-07 | 1997-06-05 | Compuestos de fungarrestina, procesos para producirlos y medicamentos para el tratamiento de tumores |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US5811420A (es) |
| EP (1) | EP0906295B1 (es) |
| JP (1) | JP3199752B2 (es) |
| KR (1) | KR100300152B1 (es) |
| CN (1) | CN1072650C (es) |
| AT (1) | ATE207471T1 (es) |
| AU (1) | AU725649B2 (es) |
| BR (1) | BR9709773A (es) |
| CA (1) | CA2257422A1 (es) |
| CO (1) | CO4940487A1 (es) |
| CZ (1) | CZ397498A3 (es) |
| DE (1) | DE69707672T2 (es) |
| DK (1) | DK0906295T3 (es) |
| ES (1) | ES2166087T3 (es) |
| HK (1) | HK1019063A1 (es) |
| HR (1) | HRP970313A2 (es) |
| HU (1) | HUP0001792A3 (es) |
| IL (1) | IL127137A0 (es) |
| MA (1) | MA24197A1 (es) |
| NO (1) | NO985685L (es) |
| NZ (1) | NZ332997A (es) |
| PE (1) | PE69598A1 (es) |
| PL (1) | PL330346A1 (es) |
| PT (1) | PT906295E (es) |
| RU (1) | RU2167871C2 (es) |
| TR (1) | TR199802517T2 (es) |
| UY (1) | UY24578A1 (es) |
| WO (1) | WO1997047611A1 (es) |
| YU (1) | YU55898A (es) |
| ZA (1) | ZA974886B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPQ307399A0 (en) * | 1999-09-24 | 1999-10-21 | Luminis Pty Limited | Cell cycle control |
| US20040058310A1 (en) * | 2002-09-20 | 2004-03-25 | Grailhe Regls Christian | Method for measuring a marker indicative of the exposure of a patient to nicotine; a kit for measuring such a marker |
| US20130203715A1 (en) | 2010-07-20 | 2013-08-08 | Pulmatrix, Inc. | Use of trp channel agonists to treat infections |
| CN109722389B (zh) * | 2017-10-31 | 2021-05-14 | 鲁南新时代生物技术有限公司 | 一种烟曲霉菌液体培养基 |
| CN108165590B (zh) * | 2017-12-20 | 2021-11-23 | 河南科技学院 | 一种烟曲霉发酵产烟曲霉素的培养基及培养方法 |
| US20240299344A1 (en) * | 2021-03-04 | 2024-09-12 | Lifemine Therapeutics | Compounds, compositions, and methods of treatment thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9120640D0 (en) * | 1991-09-27 | 1991-11-06 | Ici Plc | Tricyclic heterocycles |
| US5350763A (en) * | 1993-06-11 | 1994-09-27 | Merck & Co., Inc. | Unguinol and analogs are animal growth permittants |
| JPH0769882A (ja) * | 1993-08-27 | 1995-03-14 | Nippon Paint Co Ltd | エプスタイン−バーウィルス活性化抑制剤 |
| SG43768A1 (en) * | 1993-10-15 | 1997-11-14 | Schering Corp | Tricyclic sulfonamide compounds useful for inhibition of g-protein function and for treatment of proliferative dieases |
-
1997
- 1997-05-30 DE DE69707672T patent/DE69707672T2/de not_active Expired - Fee Related
- 1997-05-30 BR BR9709773A patent/BR9709773A/pt not_active Application Discontinuation
- 1997-05-30 PE PE1997000457A patent/PE69598A1/es not_active Application Discontinuation
- 1997-05-30 YU YU55898A patent/YU55898A/sh unknown
- 1997-05-30 KR KR1019980710016A patent/KR100300152B1/ko not_active IP Right Cessation
- 1997-05-30 PL PL97330346A patent/PL330346A1/xx unknown
- 1997-05-30 EP EP97927080A patent/EP0906295B1/en not_active Expired - Lifetime
- 1997-05-30 IL IL12713797A patent/IL127137A0/xx not_active IP Right Cessation
- 1997-05-30 AU AU31696/97A patent/AU725649B2/en not_active Ceased
- 1997-05-30 JP JP50112498A patent/JP3199752B2/ja not_active Expired - Fee Related
- 1997-05-30 PT PT97927080T patent/PT906295E/pt unknown
- 1997-05-30 CN CN97195242A patent/CN1072650C/zh not_active Expired - Fee Related
- 1997-05-30 WO PCT/EP1997/002806 patent/WO1997047611A1/en not_active Application Discontinuation
- 1997-05-30 HU HU0001792A patent/HUP0001792A3/hu unknown
- 1997-05-30 RU RU99100107/04A patent/RU2167871C2/ru not_active IP Right Cessation
- 1997-05-30 CZ CZ983974A patent/CZ397498A3/cs unknown
- 1997-05-30 ES ES97927080T patent/ES2166087T3/es not_active Expired - Lifetime
- 1997-05-30 NZ NZ332997A patent/NZ332997A/xx unknown
- 1997-05-30 DK DK97927080T patent/DK0906295T3/da active
- 1997-05-30 CA CA002257422A patent/CA2257422A1/en not_active Abandoned
- 1997-05-30 AT AT97927080T patent/ATE207471T1/de not_active IP Right Cessation
- 1997-05-30 TR TR1998/02517T patent/TR199802517T2/xx unknown
- 1997-06-03 ZA ZA9704886A patent/ZA974886B/xx unknown
- 1997-06-05 CO CO97031203A patent/CO4940487A1/es unknown
- 1997-06-05 UY UY24578A patent/UY24578A1/es unknown
- 1997-06-05 MA MA24647A patent/MA24197A1/fr unknown
- 1997-06-06 US US08/870,798 patent/US5811420A/en not_active Expired - Fee Related
- 1997-06-06 HR HR96109115.4A patent/HRP970313A2/xx not_active Application Discontinuation
-
1998
- 1998-12-04 NO NO985685A patent/NO985685L/no not_active Application Discontinuation
-
1999
- 1999-09-22 HK HK99104107A patent/HK1019063A1/xx not_active IP Right Cessation
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