CO4810300A1 - Procedimiento para preparar haluros de fenoxifenilsulfonilo - Google Patents

Procedimiento para preparar haluros de fenoxifenilsulfonilo

Info

Publication number
CO4810300A1
CO4810300A1 CO99021410A CO99021410A CO4810300A1 CO 4810300 A1 CO4810300 A1 CO 4810300A1 CO 99021410 A CO99021410 A CO 99021410A CO 99021410 A CO99021410 A CO 99021410A CO 4810300 A1 CO4810300 A1 CO 4810300A1
Authority
CO
Colombia
Prior art keywords
preparing
procedure
sulfonyl halides
alkyl
phenoxyphenyl
Prior art date
Application number
CO99021410A
Other languages
English (en)
Inventor
Joel Michael Hawkins
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of CO4810300A1 publication Critical patent/CO4810300A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C301/00—Esters of sulfurous acid
    • C07C301/02—Esters of sulfurous acid having sulfite groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/32—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of salts of sulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/26—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfonic acids
    • C07C303/28—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfonic acids by reaction of hydroxy compounds with sulfonic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/41—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing singly-bound oxygen atoms bound to the carbon skeleton
    • C07C309/42—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing singly-bound oxygen atoms bound to the carbon skeleton having the sulfo groups bound to carbon atoms of non-condensed six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/75—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing singly-bound oxygen atoms bound to the carbon skeleton

Abstract

Un procedimiento para preparar un compuesto de fórmula:en la que m es un entero de 1 a 3;R2 es fluoro, cloro, bromo, alquilo C1 -C6 , alcoxi C1 -C6 o perfluoro (alquilo C1 -C3 );que comprende hacer reaccionar un compuesto de fórmula en la que R3 es fluoro, cloro o bromo; yR4 es cloro o bromo;con un compuesto de fórmulaen la que m es un entero de 1 a 3; yR2 es fluoro, cloro, bromo, alquilo C1 -C6 , alcoxi C1 -C6 o perfluoro(alquilo C1 -C3 );En presencia de una base y un disolvente o una temperatura de O°C a aproximadamente 150°C.
CO99021410A 1998-04-10 1999-04-12 Procedimiento para preparar haluros de fenoxifenilsulfonilo CO4810300A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8139398P 1998-04-10 1998-04-10

Publications (1)

Publication Number Publication Date
CO4810300A1 true CO4810300A1 (es) 1999-06-30

Family

ID=22163859

Family Applications (1)

Application Number Title Priority Date Filing Date
CO99021410A CO4810300A1 (es) 1998-04-10 1999-04-12 Procedimiento para preparar haluros de fenoxifenilsulfonilo

Country Status (42)

Country Link
US (2) US6118016A (es)
EP (1) EP0949246B1 (es)
JP (1) JP3694419B2 (es)
KR (1) KR100329901B1 (es)
CN (1) CN1238329A (es)
AP (1) AP1155A (es)
AR (1) AR016205A1 (es)
AT (1) ATE233729T1 (es)
AU (1) AU758297B2 (es)
BG (1) BG103321A (es)
BR (1) BR9902041A (es)
CA (1) CA2268679C (es)
CO (1) CO4810300A1 (es)
DE (1) DE69905633T2 (es)
DK (1) DK0949246T3 (es)
DZ (1) DZ2755A1 (es)
EA (1) EA001756B1 (es)
ES (1) ES2192021T3 (es)
GT (1) GT199900044A (es)
HR (1) HRP990107B1 (es)
HU (1) HU221635B1 (es)
ID (1) ID23645A (es)
IL (1) IL129330A (es)
IN (1) IN191233B (es)
IS (1) IS5020A (es)
MA (1) MA24834A1 (es)
NO (1) NO991679L (es)
NZ (1) NZ335106A (es)
OA (1) OA11032A (es)
PA (1) PA8469801A1 (es)
PE (1) PE20000416A1 (es)
PL (1) PL332452A1 (es)
SG (1) SG75169A1 (es)
SI (1) SI0949246T1 (es)
SK (1) SK44999A3 (es)
TN (1) TNSN99051A1 (es)
TR (1) TR199900757A2 (es)
TW (1) TW539664B (es)
UA (1) UA59373C2 (es)
UY (1) UY25472A1 (es)
YU (1) YU18299A (es)
ZA (1) ZA992628B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458822B2 (en) 2000-03-13 2002-10-01 Pfizer Inc. 2-oxo-imidazolidine-4-carboxylic acid hydroxamide compounds that inhibit matrix metalloproteinases
ES2425013T3 (es) * 2002-06-12 2013-10-10 Symphony Evolution, Inc. Inhibidores de ADAM-10 humana
JP2006516548A (ja) 2002-12-30 2006-07-06 アンジオテック インターナショナル アクツィエン ゲゼルシャフト 迅速ゲル化ポリマー組成物からの薬物送達法
JP5830534B2 (ja) 2010-07-09 2015-12-09 ファイザー・リミテッドＰｆｉｚｅｒ Ｌｉｍｉｔｅｄ 化合物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE844004C (de) * 1944-08-06 1952-07-14 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung von Sulfonsaeureestern
US4032506A (en) * 1973-12-28 1977-06-28 General Electric Company Flame retardant polycarbonate composition
ZA794723B (en) * 1978-09-11 1980-08-27 Univ Miami Anti-hypertensive agents
GB9000725D0 (en) * 1990-01-12 1990-03-14 Pfizer Ltd Therapeutic agents
US5340489A (en) * 1992-06-05 1994-08-23 The Dow Chemical Company Aryl arenesulfonates and a method of lubrication using the aryl arenesulfonates
US5863949A (en) * 1995-03-08 1999-01-26 Pfizer Inc Arylsulfonylamino hydroxamic acid derivatives
US6153609A (en) * 1996-08-23 2000-11-28 Pfizer Inc Arylsulfonylamino hydroxamic acid derivatives
TR199901849T2 (xx) * 1997-02-03 2000-02-21 Pfizer Products Inc. Arils�lfonilamino hidroksamik asit t�revleri.
WO1998050348A1 (en) * 1997-05-09 1998-11-12 Agouron Pharmaceuticals, Inc. Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses
ATE217863T1 (de) * 1997-08-08 2002-06-15 Pfizer Prod Inc Arylsulfonylaminohydroxamsäurederivate
ATE263147T1 (de) * 1997-08-08 2004-04-15 Pfizer Prod Inc Derivate von aryloxyarylsulfonylamino hydroxyaminsäuren
PA8469401A1 (es) * 1998-04-10 2000-05-24 Pfizer Prod Inc Derivados biciclicos del acido hidroxamico

Also Published As

Publication number Publication date
AU758297B2 (en) 2003-03-20
TW539664B (en) 2003-07-01
AP9901509A0 (en) 1999-06-30
SI0949246T1 (en) 2003-06-30
US6118016A (en) 2000-09-12
GT199900044A (es) 2000-09-14
PE20000416A1 (es) 2000-05-24
EA199900282A2 (ru) 1999-10-28
EP0949246A1 (en) 1999-10-13
HU9901042D0 (en) 1999-06-28
NO991679L (no) 1999-10-11
JPH11322704A (ja) 1999-11-24
DE69905633D1 (de) 2003-04-10
IS5020A (is) 1999-10-11
NZ335106A (en) 2000-09-29
CN1238329A (zh) 1999-12-15
EA001756B1 (ru) 2001-08-27
CA2268679C (en) 2004-07-27
TR199900757A3 (tr) 1999-11-22
AR016205A1 (es) 2001-06-20
ID23645A (id) 2000-05-04
TR199900757A2 (xx) 1999-11-22
BG103321A (en) 2001-08-31
JP3694419B2 (ja) 2005-09-14
HRP990107A2 (en) 2000-02-29
HU221635B1 (hu) 2002-12-28
HUP9901042A2 (hu) 1999-12-28
ZA992628B (en) 2000-10-09
NO991679D0 (no) 1999-04-09
BR9902041A (pt) 2000-05-02
PA8469801A1 (es) 2000-09-29
EP0949246B1 (en) 2003-03-05
SG75169A1 (en) 2000-09-19
YU18299A (sh) 2002-11-15
IL129330A0 (en) 2000-02-17
KR100329901B1 (ko) 2002-03-22
AP1155A (en) 2003-06-30
UA59373C2 (uk) 2003-09-15
KR19990082980A (ko) 1999-11-25
MA24834A1 (fr) 1999-12-31
OA11032A (en) 2002-02-06
AU2369299A (en) 1999-10-21
PL332452A1 (en) 1999-10-11
DE69905633T2 (de) 2003-11-06
HRP990107B1 (en) 2003-10-31
ATE233729T1 (de) 2003-03-15
IL129330A (en) 2003-12-10
UY25472A1 (es) 1999-11-17
HUP9901042A3 (en) 2000-06-28
DZ2755A1 (fr) 2003-09-15
SK44999A3 (en) 2000-09-12
TNSN99051A1 (fr) 2005-11-10
ES2192021T3 (es) 2003-09-16
CA2268679A1 (en) 1999-10-10
DK0949246T3 (da) 2003-04-07
US20010011143A1 (en) 2001-08-02
EA199900282A3 (ru) 2000-04-24
IN191233B (es) 2003-10-11

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