CO4410189A1 - Procedimiento de preparacion de trihidrato de (2r.3s) -3- tert-butoxicarbonilamino-2-hidroxi-3-fenilpropionato de 4-acetoxi-2(alfa)-bezoiloxi-5(beta),20-epoxi-1,7(beta),10 (beta)-trihidroxi-9-oxo-tax-11-en-13(alfa)ilo - Google Patents
Procedimiento de preparacion de trihidrato de (2r.3s) -3- tert-butoxicarbonilamino-2-hidroxi-3-fenilpropionato de 4-acetoxi-2(alfa)-bezoiloxi-5(beta),20-epoxi-1,7(beta),10 (beta)-trihidroxi-9-oxo-tax-11-en-13(alfa)iloInfo
- Publication number
- CO4410189A1 CO4410189A1 CO95029779A CO95029779A CO4410189A1 CO 4410189 A1 CO4410189 A1 CO 4410189A1 CO 95029779 A CO95029779 A CO 95029779A CO 95029779 A CO95029779 A CO 95029779A CO 4410189 A1 CO4410189 A1 CO 4410189A1
- Authority
- CO
- Colombia
- Prior art keywords
- beta
- alpha
- epoxi
- tax
- tert
- Prior art date
Links
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 abstract 1
- -1 CARBONYLAMINE-2-HYDROXY-3-PHENYLPROPIONATE Chemical compound 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000004684 trihydrates Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9408479A FR2722191B1 (fr) | 1994-07-08 | 1994-07-08 | Procede de preparation du trihydrate du (2r,3s)-3-tertbutoxycarbonylamino-2-hydroxy-3-phenylpropionate de 4-acetoxy2alpha-benzoyloxy-5beta,20epoxy-1,7beta,10beta trihydroxy-9-oxo-tax-11-en-13alpha-yle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO4410189A1 true CO4410189A1 (es) | 1997-01-09 |
Family
ID=9465183
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO95029779A CO4410189A1 (es) | 1994-07-08 | 1995-07-07 | Procedimiento de preparacion de trihidrato de (2r.3s) -3- tert-butoxicarbonilamino-2-hidroxi-3-fenilpropionato de 4-acetoxi-2(alfa)-bezoiloxi-5(beta),20-epoxi-1,7(beta),10 (beta)-trihidroxi-9-oxo-tax-11-en-13(alfa)ilo |
Country Status (38)
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998049321A2 (en) | 1997-04-28 | 1998-11-05 | Rhone-Poulenc Rorer S.A. | Adenovirus-mediated intratumoral delivery of an angiogenesis antagonist for the treatment of tumors |
| SE510650C2 (sv) * | 1997-05-30 | 1999-06-14 | Astra Ab | Ny förening |
| FR2794771B1 (fr) | 1999-06-11 | 2001-08-10 | Aventis Pharma Sa | Adenovirus recombinants codant pour le transporteur specifique de l'iode (nis) |
| US6853921B2 (en) | 1999-07-20 | 2005-02-08 | Halliburton Energy Services, Inc. | System and method for real time reservoir management |
| US6266619B1 (en) * | 1999-07-20 | 2001-07-24 | Halliburton Energy Services, Inc. | System and method for real time reservoir management |
| GB9920548D0 (en) * | 1999-08-31 | 1999-11-03 | Rhone Poulenc Rorer Sa | Treatment of hepatocellular carcinoma |
| US6891050B2 (en) * | 2001-08-10 | 2005-05-10 | Dabur India Limited | Process for the preparation of taxanes such as paclitaxel, docetaxel and structurally similar analogs |
| US6881852B2 (en) * | 2002-02-05 | 2005-04-19 | Dabur India Limited | Process of purification of paclitaxel and docetaxel |
| US7247738B2 (en) * | 2002-05-07 | 2007-07-24 | Dabur India Limited | Method of preparation of anticancer taxanes using 3-[(substituted-2-trialkylsilyl) ethoxycarbonyl]-5-oxazolidine carboxylic acids |
| US6900342B2 (en) * | 2002-05-10 | 2005-05-31 | Dabur India Limited | Anticancer taxanes such as paclitaxel, docetaxel and their structural analogs, and a method for the preparation thereof |
| US6838569B2 (en) * | 2002-12-16 | 2005-01-04 | Dabur India Limited | Process for preparation of paclitaxel trihydrate and docetaxel trihydrate |
| US7584165B2 (en) * | 2003-01-30 | 2009-09-01 | Landmark Graphics Corporation | Support apparatus, method and system for real time operations and maintenance |
| US8703982B2 (en) | 2003-03-17 | 2014-04-22 | Phyton Holdings Llc | Purification of taxanes |
| CN1268619C (zh) * | 2003-05-08 | 2006-08-09 | 上海迪赛诺化学制药有限公司 | 多烯紫杉醇三水化合物的制备方法 |
| FR2859996B1 (fr) * | 2003-09-19 | 2006-02-03 | Aventis Pharma Sa | Solvat acetonique du dimethoxy docetaxel et son procede de preparation |
| WO2005061474A1 (en) | 2003-12-12 | 2005-07-07 | Quiral Química Do Brasil | Process for the preparation of anhydrous and hydrated active pharmaceutical ingredients (apis); stable pharmaceutical compositions prepared from the same and uses of said compositions |
| US7142986B2 (en) * | 2005-02-01 | 2006-11-28 | Smith International, Inc. | System for optimizing drilling in real time |
| CN100420681C (zh) * | 2005-04-29 | 2008-09-24 | 上海奥锐特国际贸易有限公司 | 多烯紫杉醇三水物的制备方法 |
| PT3311805T (pt) * | 2005-08-31 | 2020-04-21 | Abraxis Bioscience Llc | Composições compreendendo agentes farmacêuticos pouco hidrossolúveis e agentes antimicrobianos |
| BRPI0615292A8 (pt) * | 2005-08-31 | 2018-03-06 | Abraxis Bioscience Llc | composições e métodos para preparação de fármacos de má solubilidade em água com estabilidade aumentada |
| WO2007044950A2 (en) * | 2005-10-12 | 2007-04-19 | Sicor, Inc. | Crystalline forms of docetaxel and processes for their preparation |
| KR100995390B1 (ko) | 2006-01-02 | 2010-11-19 | 주식회사 삼양제넥스 | 무정형, 무수결정형 또는 수화 결정형 도세탁셀의 제조방법 |
| MX2008009308A (es) * | 2006-01-20 | 2008-10-03 | Landmark Graphics Corp | Administracion del sistema de produccion dinamica. |
| US20100160653A1 (en) * | 2006-03-21 | 2010-06-24 | Dr. Reddy's Laboratories Ltd. | Docetaxel polymorphs and processes |
| EP2094084A4 (en) * | 2006-10-20 | 2010-01-13 | Scinopharm Singapore Pte Ltd | PROCESS FOR PREPARING CRYSTALLINE WATER-FREE DOCETAXEL |
| KR100868116B1 (ko) | 2007-04-09 | 2008-11-10 | 한미약품 주식회사 | 도세탁셀·모노프로필렌글라이콜 내포화합물 및 이의제조방법 |
| KR100878455B1 (ko) | 2007-04-10 | 2009-01-13 | 한미약품 주식회사 | 안정한 무수결정형 도세탁셀 및 이의 제조방법 |
| WO2009006590A2 (en) * | 2007-07-04 | 2009-01-08 | Dr. Reddy's Laboratories Ltd. | Docetaxel process and polymorphs |
| ES2389518T3 (es) * | 2008-01-18 | 2012-10-26 | Indena S.P.A. | Formas sólidas de ortataxel |
| EP2080763A1 (en) * | 2008-01-18 | 2009-07-22 | INDENA S.p.A. | Crystalline form I of ortataxel |
| PL388144A1 (pl) | 2009-05-29 | 2010-12-06 | Przedsiębiorstwo Produkcyjno-Wdrożeniowe Ifotam Spółka Z Ograniczoną Odpowiedzialnością | Solwaty (2R,3S)-3-tert-butoksykarbonylamino-2-hydroksy-3-fenylopropionianu 4-acetoksy-2α-benzoiloksy -5β,20-epoksy-1,7β,10β-trihydroksy-9-okso-taks-11-en-13α-ylu, sposób ich otrzymywania i zastosowanie |
| US8686165B2 (en) * | 2009-11-04 | 2014-04-01 | Emcure Pharmaceuticals Limited | Process for preparation of taxane derivatives |
| KR101752944B1 (ko) | 2010-05-03 | 2017-07-03 | 테이코쿠 팔마 유에스에이, 인코포레이티드 | 비수성의 탁산 프로에멀젼 제제, 및 그의 제조 및 사용 방법 |
| WO2012160568A1 (en) * | 2011-05-23 | 2012-11-29 | Shilpa Medicare Limited | Process for preparing docetaxel trihydrate polymorph |
| SI2753355T1 (sl) | 2011-09-08 | 2019-02-28 | New York University | Onkolitični virus herpesa simpleksa in njegove terapevtske uporabe |
| WO2013096455A1 (en) | 2011-12-20 | 2013-06-27 | Dana-Farber Cancer Institute, Inc. | Methods for diagnosing and treating oncogenic kras-associated cancer |
| KR101809858B1 (ko) | 2012-04-04 | 2017-12-15 | 할로자임, 아이엔씨 | 항-히알루로난 제제 및 종양-표적 탁산을 이용한 병용 치료 |
| CA2874521A1 (en) | 2012-05-24 | 2013-11-28 | Dana-Farber Cancer Institute, Inc. | Targeting the glutamine to pyruvate pathway for treatment of oncogenic kras-associated cancer |
| WO2014014518A1 (en) | 2012-07-18 | 2014-01-23 | Dana-Farber Cancer Institute, Inc. | Methods for treating, preventing and predicting risk of developing breast cancer |
| JO3685B1 (ar) | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
| WO2014149871A1 (en) | 2013-03-14 | 2014-09-25 | Icahn School Of Medicine At Mount Sinai | Autologous tumor lysate-loaded dendritic cell vaccine for treatment of liver cancer |
| WO2015050844A1 (en) | 2013-10-01 | 2015-04-09 | Dana-Farber Cancer Institute, Inc. | Methods of treating cancer with atovaquone-related compounds |
| US10350264B2 (en) | 2014-03-27 | 2019-07-16 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for modulating NCOA4-mediated autophagic targeting of ferritin |
| MA39818A (fr) | 2014-03-30 | 2017-02-08 | Benevir Biopharm Inc | Virus oncolytiques « armés » comprenant un inhibiteur de tap exogène et leurs utilisations thérapeutiques |
| EP3307330B1 (en) | 2015-06-15 | 2021-03-10 | New York University | Method of treatment using oncolytic viruses |
| WO2019222435A1 (en) | 2018-05-16 | 2019-11-21 | Halozyme, Inc. | Methods of selecting subjects for combination cancer therapy with a polymer-conjugated soluble ph20 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2601675B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
| US5229526A (en) * | 1991-09-23 | 1993-07-20 | Florida State University | Metal alkoxides |
-
1994
- 1994-07-08 FR FR9408479A patent/FR2722191B1/fr not_active Expired - Fee Related
-
1995
- 1995-06-22 IL IL11427495A patent/IL114274A/xx not_active IP Right Cessation
- 1995-07-03 UY UY23991A patent/UY23991A1/es not_active IP Right Cessation
- 1995-07-04 DZ DZ950082A patent/DZ1905A1/fr active
- 1995-07-05 TN TNTNSN95071A patent/TNSN95071A1/fr unknown
- 1995-07-05 PE PE1995272899A patent/PE8697A1/es not_active IP Right Cessation
- 1995-07-06 ZA ZA955646A patent/ZA955646B/xx unknown
- 1995-07-06 MA MA23945A patent/MA23606A1/fr unknown
- 1995-07-06 IN IN1260DE1995 patent/IN183947B/en unknown
- 1995-07-06 MY MYPI95001895A patent/MY118481A/en unknown
- 1995-07-06 TW TW084106974A patent/TW419473B/zh not_active IP Right Cessation
- 1995-07-07 MX MX9700173A patent/MX9700173A/es unknown
- 1995-07-07 ES ES95925022T patent/ES2121404T3/es not_active Expired - Lifetime
- 1995-07-07 US US08/776,333 patent/US6022985A/en not_active Expired - Lifetime
- 1995-07-07 AT AT95925022T patent/ATE171702T1/de active
- 1995-07-07 SI SI9530138T patent/SI0770070T1/xx unknown
- 1995-07-07 CA CA002193531A patent/CA2193531C/fr not_active Expired - Lifetime
- 1995-07-07 BR BR9508789A patent/BR9508789A/pt not_active Application Discontinuation
- 1995-07-07 CO CO95029779A patent/CO4410189A1/es unknown
- 1995-07-07 RU RU97101875A patent/RU2126397C1/ru active
- 1995-07-07 DE DE69505128T patent/DE69505128T2/de not_active Expired - Lifetime
- 1995-07-07 UA UA97010077A patent/UA51624C2/uk unknown
- 1995-07-07 NZ NZ289455A patent/NZ289455A/en not_active IP Right Cessation
- 1995-07-07 SK SK6-97A patent/SK280520B6/sk not_active IP Right Cessation
- 1995-07-07 CN CN95193984A patent/CN1067996C/zh not_active Expired - Lifetime
- 1995-07-07 KR KR1019970700118A patent/KR100391753B1/ko not_active Expired - Lifetime
- 1995-07-07 DK DK95925022T patent/DK0770070T3/da active
- 1995-07-07 AU AU29305/95A patent/AU706519B2/en not_active Expired
- 1995-07-07 WO PCT/FR1995/000910 patent/WO1996001815A1/fr active IP Right Grant
- 1995-07-07 EP EP95925022A patent/EP0770070B1/fr not_active Expired - Lifetime
- 1995-07-07 JP JP50415896A patent/JP3753155B2/ja not_active Expired - Fee Related
- 1995-07-07 HU HU9700041A patent/HU220634B1/hu unknown
- 1995-07-07 PL PL95318195A patent/PL179876B1/pl unknown
- 1995-07-07 CZ CZ9735A patent/CZ284695B6/cs not_active IP Right Cessation
-
1997
- 1997-01-02 NO NO19970007A patent/NO314500B1/no not_active IP Right Cessation
- 1997-01-07 FI FI970069A patent/FI119246B/fi not_active IP Right Cessation
- 1997-01-07 IS IS4411A patent/IS2032B/is unknown
-
1998
- 1998-01-01 GR GR980400355T patent/GR3027558T3/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CO4410189A1 (es) | Procedimiento de preparacion de trihidrato de (2r.3s) -3- tert-butoxicarbonilamino-2-hidroxi-3-fenilpropionato de 4-acetoxi-2(alfa)-bezoiloxi-5(beta),20-epoxi-1,7(beta),10 (beta)-trihidroxi-9-oxo-tax-11-en-13(alfa)ilo | |
| CU22772A3 (es) | Suplementos alimenticios que contienen flavonol | |
| DE69213617D1 (de) | Kombinierte Extruderkopf Anordnung zur Herstellung eines Dichtungsstreifens | |
| CO4700286A1 (es) | PROCEDIMIENTO DE PREPARACION DEL TRIHIDRATO DEL (2R,3S)-3- BENZOILAMINO-2-HIDROXI-3-FENILPROPIONATO DE 4,10-DIACETOXI- 2(alfa)-BENZOILOXI-5(beta),20-EPOXI-1,7(beta)-DIHIDROXI-9- OXO-TAX-11-EN 13(beta)-ILO | |
| DK153225C (da) | Dieselbraendstof | |
| FR2514765B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | ||
| DK157035C (da) | Biologisk ren mikroorganismestamme samt fremgangsmaade til fremstilling af et dyrkningsprodukt heraf til anvendelse som et hudpraeparat | |
| IT1207299B (it) | Uniforme di un letto catalizzaotre dispositivo per l'alimentazione con un gas di scarico da depurare. | |
| FR2746108B1 (fr) | Procede de concentration d'une solution telle que mouts de raisin a basse temperature et pression atmospherique | |
| PH16452A (en) | Composition containing cinnamycin and use thereof | |
| ES2026507T3 (es) | Procedimiento para la obtencion en continuo de compuestos alifaticos que contienen grupos carbalcoxi. | |
| ECSP961646A (es) | PROCESO DE PREPARACION DEL TRIHIDRATO DE (2R,3S)-3-BENZOYLAMINO - 2 - HIDROXI - 3 - FENIL-PROPIONATO DE 4, 10 - DIACETOXI - 2 a- BENZOYLOXI - 5ß, 20 - EPOXI- 1, 7ß - DIHIDROXI - 9 - OXO - TAX - 11 - EN - 13 ßYLE | |
| PT73593A (fr) | Procede de preparation de derives d'aminothiols leur utilisation ainsi que compositions contenant ces derives | |
| GB1553662A (en) | Sterilization of fermentation media | |
| BE818145A (fr) | Nouveaux esters amino-ethyliques n-disubstitues de la raubasineet procede d'obtention. | |
| ATE7500T1 (de) | Verfahren zur herstellung neuer sauerstoffhaltiger heterocyclen. | |
| IT1130943B (it) | Coltura termofila anaeroba di produttore di alcool | |
| TH20161A (th) | กรรมวิธีการเตรียม 4-อะเซตทอกซี-2อัลฟา-เบนโซอิลออกซิ-5เบตา, 20-อีพอกซี-1, 7เบตา, 10เบตา-ไทรไธดรอกซี-9-ออกโซ-แทกซ์-11-เอ็น-13อัลฟา-อิล (2r, 3s)-3-เทอร์ท-บิวทอกซี-คาร์บอนิลอะมิโน-2-ไฮดรอกซิ-3-ฟีนิลโพรพิออเนต ไทรไฮเดรต | |
| KR830004412A (ko) | 밀디오 마이신의 제조법 | |
| JPS51121588A (en) | Culture medium for identifying bacteria | |
| JPS533585A (en) | Preparation of l-serine | |
| KR830008667A (ko) | 투명한 젤스틱 | |
| JPS54163256A (en) | Radial static pressure bearing for static pressure screw |