CO2020001740A2 - Agentes de iarn y composiciones para inhibir la expresión de la angiopoyetina tipo 3 (angptl3) y métodos de uso - Google Patents

Agentes de iarn y composiciones para inhibir la expresión de la angiopoyetina tipo 3 (angptl3) y métodos de uso

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Publication number
CO2020001740A2
CO2020001740A2 CONC2020/0001740A CO2020001740A CO2020001740A2 CO 2020001740 A2 CO2020001740 A2 CO 2020001740A2 CO 2020001740 A CO2020001740 A CO 2020001740A CO 2020001740 A2 CO2020001740 A2 CO 2020001740A2
Authority
CO
Colombia
Prior art keywords
angptl3
agents
compositions
irna agents
methods
Prior art date
Application number
CONC2020/0001740A
Other languages
English (en)
Spanish (es)
Inventor
Zhen Li
Rui Zhu
So Wong
Original Assignee
Arrowhead Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arrowhead Pharmaceuticals Inc filed Critical Arrowhead Pharmaceuticals Inc
Publication of CO2020001740A2 publication Critical patent/CO2020001740A2/es

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    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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CONC2020/0001740A 2017-09-14 2020-02-14 Agentes de iarn y composiciones para inhibir la expresión de la angiopoyetina tipo 3 (angptl3) y métodos de uso CO2020001740A2 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762558819P 2017-09-14 2017-09-14
US201762583919P 2017-11-09 2017-11-09
US201862651284P 2018-04-02 2018-04-02
US201862694976P 2018-07-07 2018-07-07
PCT/US2018/050848 WO2019055633A1 (en) 2017-09-14 2018-09-13 RNAI AGENTS AND COMPOSITIONS FOR INHIBITING ANALOGUE EXPRESSION OF ANGIOPOIETIN 3 (ANGPTL3) AND METHODS OF USE

Publications (1)

Publication Number Publication Date
CO2020001740A2 true CO2020001740A2 (es) 2020-05-29

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ID=65630620

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CONC2020/0001740A CO2020001740A2 (es) 2017-09-14 2020-02-14 Agentes de iarn y composiciones para inhibir la expresión de la angiopoyetina tipo 3 (angptl3) y métodos de uso

Country Status (23)

Country Link
US (2) US10995335B2 (https=)
EP (1) EP3681513A4 (https=)
JP (3) JP7281452B2 (https=)
KR (2) KR20250004009A (https=)
CN (2) CN117701562A (https=)
AU (2) AU2018331383B2 (https=)
BR (1) BR112020003126A2 (https=)
CA (1) CA3074320A1 (https=)
CL (1) CL2020000666A1 (https=)
CO (1) CO2020001740A2 (https=)
EC (1) ECSP20018305A (https=)
IL (2) IL273173B2 (https=)
JO (1) JOP20200050A1 (https=)
MX (1) MX2020001912A (https=)
MY (1) MY200087A (https=)
PE (1) PE20201287A1 (https=)
PH (1) PH12020500309A1 (https=)
SG (1) SG11201912188RA (https=)
TN (1) TN2020000038A1 (https=)
TW (2) TWI823866B (https=)
UY (1) UY37881A (https=)
WO (1) WO2019055633A1 (https=)
ZA (1) ZA202103669B (https=)

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