CO2019007685A2 - Método para tratar o mejorar trastornos metabólicos mediante el uso de agonistas del receptor glp-1 conjugados con antagonistas del receptor del péptido inhibidor gástrico (gipr) - Google Patents

Método para tratar o mejorar trastornos metabólicos mediante el uso de agonistas del receptor glp-1 conjugados con antagonistas del receptor del péptido inhibidor gástrico (gipr)

Info

Publication number
CO2019007685A2
CO2019007685A2 CONC2019/0007685A CO2019007685A CO2019007685A2 CO 2019007685 A2 CO2019007685 A2 CO 2019007685A2 CO 2019007685 A CO2019007685 A CO 2019007685A CO 2019007685 A2 CO2019007685 A2 CO 2019007685A2
Authority
CO
Colombia
Prior art keywords
glp
gipr
treat
conjugated
metabolic disorders
Prior art date
Application number
CONC2019/0007685A
Other languages
English (en)
Spanish (es)
Inventor
Yuan Cheng
Chawita Netirojjanakul
Bin Wu
Jerry Ryan Holder
James R Falsey
Kelvin Sham
Leslie P Miranda
Shu-Chen Lu
Bradley J Herberich
Murielle M Veniant-Ellison
Jing Xu
Shanaka Stanislaus
Junming Yie
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=61832572&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO2019007685(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of CO2019007685A2 publication Critical patent/CO2019007685A2/es

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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6847—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a hormone or a hormone-releasing or -inhibiting factor
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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CONC2019/0007685A 2017-01-17 2019-07-17 Método para tratar o mejorar trastornos metabólicos mediante el uso de agonistas del receptor glp-1 conjugados con antagonistas del receptor del péptido inhibidor gástrico (gipr) CO2019007685A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762447332P 2017-01-17 2017-01-17
PCT/US2018/013918 WO2018136440A1 (en) 2017-01-17 2018-01-16 Method of treating or ameliorating metabolic disorders using glp-1 receptor agonists conjugated to antagonists for gastric inhibitory peptide receptor (gipr)

Publications (1)

Publication Number Publication Date
CO2019007685A2 true CO2019007685A2 (es) 2019-07-31

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CONC2019/0007685A CO2019007685A2 (es) 2017-01-17 2019-07-17 Método para tratar o mejorar trastornos metabólicos mediante el uso de agonistas del receptor glp-1 conjugados con antagonistas del receptor del péptido inhibidor gástrico (gipr)

Country Status (38)

Country Link
US (3) US10905772B2 (https=)
EP (2) EP3570885B1 (https=)
JP (3) JP7175899B2 (https=)
KR (3) KR20250038835A (https=)
CN (2) CN110662558B (https=)
AR (1) AR110751A1 (https=)
AU (2) AU2018210858B2 (https=)
BR (1) BR112019014588A2 (https=)
CA (1) CA3049023A1 (https=)
CL (1) CL2019001963A1 (https=)
CO (1) CO2019007685A2 (https=)
CR (2) CR20230302A (https=)
DK (1) DK3570885T3 (https=)
EA (1) EA201991721A1 (https=)
ES (1) ES3009462T3 (https=)
FI (1) FI3570885T3 (https=)
HR (1) HRP20241563T1 (https=)
HU (1) HUE069334T2 (https=)
IL (2) IL313587A (https=)
JO (1) JOP20190177B1 (https=)
LT (1) LT3570885T (https=)
MA (1) MA47314B1 (https=)
MD (1) MD3570885T2 (https=)
MX (2) MX2019008462A (https=)
NZ (1) NZ754937A (https=)
PE (2) PE20191467A1 (https=)
PH (1) PH12019501656A1 (https=)
PL (1) PL3570885T3 (https=)
PT (1) PT3570885T (https=)
RS (1) RS66291B1 (https=)
SA (1) SA519402246B1 (https=)
SG (1) SG11201906525SA (https=)
SI (1) SI3570885T1 (https=)
SM (1) SMT202400502T1 (https=)
TW (1) TWI708613B (https=)
UY (1) UY37568A (https=)
WO (1) WO2018136440A1 (https=)
ZA (1) ZA201904287B (https=)

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