AR075998A1 - Tratamiento de trastornos resistentes a insulina.composicion farmaceutica. uso. kit - Google Patents
Tratamiento de trastornos resistentes a insulina.composicion farmaceutica. uso. kitInfo
- Publication number
- AR075998A1 AR075998A1 ARP100101033A ARP100101033A AR075998A1 AR 075998 A1 AR075998 A1 AR 075998A1 AR P100101033 A ARP100101033 A AR P100101033A AR P100101033 A ARP100101033 A AR P100101033A AR 075998 A1 AR075998 A1 AR 075998A1
- Authority
- AR
- Argentina
- Prior art keywords
- insulin resistance
- kit
- treatment
- pharmaceutical composition
- insulin
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title abstract 4
- 102000004877 Insulin Human genes 0.000 title abstract 2
- 108090001061 Insulin Proteins 0.000 title abstract 2
- 229940125396 insulin Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 5
- 206010022489 Insulin Resistance Diseases 0.000 abstract 4
- 102000013691 Interleukin-17 Human genes 0.000 abstract 4
- 108050003558 Interleukin-17 Proteins 0.000 abstract 4
- 239000003795 chemical substances by application Substances 0.000 abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 208000035475 disorder Diseases 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 2
- 239000005557 antagonist Substances 0.000 abstract 2
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 102000004218 Insulin-Like Growth Factor I Human genes 0.000 abstract 1
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 229940100389 Sulfonylurea Drugs 0.000 abstract 1
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 201000010066 hyperandrogenism Diseases 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 230000002611 ovarian Effects 0.000 abstract 1
- YROXIXLRRCOBKF-UHFFFAOYSA-N sulfonylurea Chemical class OC(=N)N=S(=O)=O YROXIXLRRCOBKF-UHFFFAOYSA-N 0.000 abstract 1
- 208000035408 type 1 diabetes mellitus 1 Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Emergency Medicine (AREA)
- Reproductive Health (AREA)
- Child & Adolescent Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Reivindicacion 1: Un método para tratar un trastorno de resistencia a insulina en un mamífero que comprende administrar a un mamífero que lo necesite una cantidad efectiva de un antagonista de IL-17A y/o IL-17F. Reivindicacion 2: El método de acuerdo con la reivindicacion 1, en donde el trastorno es seleccionado del grupo que consiste de diabetes mellitus insulinodependiente (NIDDM), obesidad, hiperandrogenismo ovárico e hipertension. Reivindicacion 5: El método de acuerdo con la reivindicacion 1, en donde el antagonista IL-17A y/o IL-17F es un anticuerpo o uno de sus fragmentos. Reivindicacion 6: El método de acuerdo con la reivindicacion 5, en donde el anticuerpo es un anticuerpo seleccionado del grupo que consiste de anticuerpos anti-IL-17A, anti-IL-17F, anti-IL-17A/F y anti-IL-17Rc. Reivindicacion 10: El método de acuerdo con la reivindicacion 9 que además comprende administrar una cantidad efectiva de un agente para tratar la resistencia a insulina. Reivindicacion 11: El método de acuerdo con la reivindicacion 10, en donde el agente para tratar la resistencia a insulina es insulina, IGF-1 o una sulfonilurea. Reivindicacion 12: El método de acuerdo con la reivindicacion 10 que además comprende una cantidad efectiva de otro agente capaz de tratar dicho trastorno de resistencia a insulina. Reivindicacion 13: El método de acuerdo con la reivindicacion 12, en donde el otro agente es Dickkopf-5 (Dkk-5).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16567709P | 2009-04-01 | 2009-04-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR075998A1 true AR075998A1 (es) | 2011-05-11 |
Family
ID=42229822
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP100101033A AR075998A1 (es) | 2009-04-01 | 2010-03-30 | Tratamiento de trastornos resistentes a insulina.composicion farmaceutica. uso. kit |
Country Status (24)
Country | Link |
---|---|
US (1) | US20100266595A1 (es) |
EP (1) | EP2413967A1 (es) |
JP (1) | JP5795306B2 (es) |
KR (1) | KR101766927B1 (es) |
CN (1) | CN102448493B (es) |
AR (1) | AR075998A1 (es) |
AU (1) | AU2010232692C1 (es) |
BR (1) | BRPI1011535A2 (es) |
CA (1) | CA2752908A1 (es) |
CL (1) | CL2011002416A1 (es) |
CO (1) | CO6410313A2 (es) |
CR (1) | CR20110552A (es) |
EC (1) | ECSP11011429A (es) |
IL (1) | IL214745A0 (es) |
MA (1) | MA33248B1 (es) |
MX (1) | MX347978B (es) |
NZ (1) | NZ595005A (es) |
PE (1) | PE20120628A1 (es) |
RU (1) | RU2537142C2 (es) |
SG (1) | SG174891A1 (es) |
TW (1) | TWI474833B (es) |
UA (1) | UA105384C2 (es) |
WO (1) | WO2010114859A1 (es) |
ZA (1) | ZA201106076B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050118232A1 (en) * | 2002-02-12 | 2005-06-02 | Elvira Pistolesi | N-acyl-phosphatidyl-ethanolamines and/or mixtures of n-acyl-ethanolamines with phosphatidic acids or lysophosphatidic acids |
CA2721713C (en) | 2008-05-05 | 2019-07-09 | Novimmune Sa | Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof |
US8790642B2 (en) | 2008-08-29 | 2014-07-29 | Genentech, Inc. | Cross-reactive and bispecific anti-IL-17A/F antibodies |
AR083546A1 (es) | 2010-10-25 | 2013-03-06 | Genentech Inc | Tratamiento de inflamacion gastrointestinal, soriasis y asma |
US9117641B2 (en) | 2012-10-29 | 2015-08-25 | Perkinelmer Health Sciences, Inc. | Direct sample analysis device adapters and methods of using them |
SG10201913433SA (en) * | 2013-02-04 | 2020-03-30 | Sanofi Sa | Stabilized pharmaceutical formulations of insulin analogues and/or insulin derivatives |
TWI641381B (zh) * | 2013-02-04 | 2018-11-21 | 法商賽諾菲公司 | 胰島素類似物及/或胰島素衍生物之穩定化醫藥調配物 |
SG11201604710XA (en) | 2014-01-09 | 2016-07-28 | Sanofi Sa | Stabilized pharmaceutical formulations of insulin analogues and/or insulin derivatives |
EP3592771A4 (en) * | 2017-03-10 | 2020-09-09 | Suzhou Kanova Biopharmaceutical Co., Ltd. | MONOCLONAL ANTIBODIES AGAINST BOTH IL-17A AND IL-17F AND USE THEREOF |
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-
2010
- 2010-03-30 MX MX2011010273A patent/MX347978B/es active IP Right Grant
- 2010-03-30 RU RU2011144122/15A patent/RU2537142C2/ru not_active IP Right Cessation
- 2010-03-30 EP EP10712243A patent/EP2413967A1/en not_active Withdrawn
- 2010-03-30 PE PE2011001691A patent/PE20120628A1/es not_active Application Discontinuation
- 2010-03-30 JP JP2012503632A patent/JP5795306B2/ja active Active
- 2010-03-30 CA CA2752908A patent/CA2752908A1/en not_active Abandoned
- 2010-03-30 SG SG2011068293A patent/SG174891A1/en unknown
- 2010-03-30 KR KR1020117025865A patent/KR101766927B1/ko active IP Right Grant
- 2010-03-30 AU AU2010232692A patent/AU2010232692C1/en not_active Ceased
- 2010-03-30 UA UAA201112634A patent/UA105384C2/ru unknown
- 2010-03-30 US US12/749,876 patent/US20100266595A1/en not_active Abandoned
- 2010-03-30 TW TW099109698A patent/TWI474833B/zh not_active IP Right Cessation
- 2010-03-30 NZ NZ595005A patent/NZ595005A/en not_active IP Right Cessation
- 2010-03-30 AR ARP100101033A patent/AR075998A1/es not_active Application Discontinuation
- 2010-03-30 BR BRPI1011535A patent/BRPI1011535A2/pt not_active IP Right Cessation
- 2010-03-30 CN CN201080023924.3A patent/CN102448493B/zh active Active
- 2010-03-30 WO PCT/US2010/029280 patent/WO2010114859A1/en active Application Filing
- 2010-03-30 MA MA34316A patent/MA33248B1/fr unknown
-
2011
- 2011-08-18 IL IL214745A patent/IL214745A0/en unknown
- 2011-08-18 ZA ZA2011/06076A patent/ZA201106076B/en unknown
- 2011-08-24 CO CO11108185A patent/CO6410313A2/es not_active Application Discontinuation
- 2011-09-30 CL CL2011002416A patent/CL2011002416A1/es unknown
- 2011-10-19 CR CR20110552A patent/CR20110552A/es unknown
- 2011-11-01 EC EC2011011429A patent/ECSP11011429A/es unknown
Also Published As
Publication number | Publication date |
---|---|
IL214745A0 (en) | 2011-11-30 |
PE20120628A1 (es) | 2012-05-26 |
KR101766927B1 (ko) | 2017-08-09 |
MX347978B (es) | 2017-05-22 |
CO6410313A2 (es) | 2012-03-30 |
RU2011144122A (ru) | 2013-05-10 |
ZA201106076B (en) | 2012-11-28 |
AU2010232692A1 (en) | 2011-09-08 |
TW201038284A (en) | 2010-11-01 |
KR20120005483A (ko) | 2012-01-16 |
SG174891A1 (en) | 2011-11-28 |
EP2413967A1 (en) | 2012-02-08 |
CR20110552A (es) | 2011-12-07 |
CN102448493B (zh) | 2014-04-30 |
UA105384C2 (ru) | 2014-05-12 |
JP5795306B2 (ja) | 2015-10-14 |
MA33248B1 (fr) | 2012-05-02 |
WO2010114859A1 (en) | 2010-10-07 |
BRPI1011535A2 (pt) | 2016-03-29 |
AU2010232692B2 (en) | 2016-12-01 |
NZ595005A (en) | 2014-04-30 |
AU2010232692C1 (en) | 2017-06-01 |
JP2012522788A (ja) | 2012-09-27 |
MX2011010273A (es) | 2011-10-17 |
CA2752908A1 (en) | 2010-10-07 |
CL2011002416A1 (es) | 2012-04-20 |
CN102448493A (zh) | 2012-05-09 |
TWI474833B (zh) | 2015-03-01 |
ECSP11011429A (es) | 2011-12-30 |
US20100266595A1 (en) | 2010-10-21 |
RU2537142C2 (ru) | 2014-12-27 |
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