CO2019006657A2 - Anticuerpos anti-cd73 y usos de los mismos - Google Patents

Anticuerpos anti-cd73 y usos de los mismos

Info

Publication number
CO2019006657A2
CO2019006657A2 CONC2019/0006657A CO2019006657A CO2019006657A2 CO 2019006657 A2 CO2019006657 A2 CO 2019006657A2 CO 2019006657 A CO2019006657 A CO 2019006657A CO 2019006657 A2 CO2019006657 A2 CO 2019006657A2
Authority
CO
Colombia
Prior art keywords
seq
antibodies
fragments
cdr1
cdr2
Prior art date
Application number
CONC2019/0006657A
Other languages
English (en)
Spanish (es)
Inventor
Zhengyi Wang
Lei Fang
Jingwu Zang
Bingshi Guo
Original Assignee
I‐Mab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by I‐Mab filed Critical I‐Mab
Publication of CO2019006657A2 publication Critical patent/CO2019006657A2/es

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/565—Complementarity determining region [CDR]
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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    • G01N2333/914—Hydrolases (3)
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
CONC2019/0006657A 2017-01-24 2019-06-21 Anticuerpos anti-cd73 y usos de los mismos CO2019006657A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2017072445 2017-01-24
PCT/CN2018/073746 WO2018137598A1 (en) 2017-01-24 2018-01-23 Anti-cd73 antibodies and uses thereof

Publications (1)

Publication Number Publication Date
CO2019006657A2 true CO2019006657A2 (es) 2019-06-28

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CONC2019/0006657A CO2019006657A2 (es) 2017-01-24 2019-06-21 Anticuerpos anti-cd73 y usos de los mismos

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US (2) US10584169B2 (enExample)
EP (2) EP4050030A1 (enExample)
JP (1) JP7206193B2 (enExample)
KR (3) KR20180093088A (enExample)
CN (2) CN112279918A (enExample)
AU (3) AU2018213549B2 (enExample)
BR (1) BR112019012040A2 (enExample)
CA (1) CA3045376C (enExample)
CL (1) CL2019001756A1 (enExample)
CO (1) CO2019006657A2 (enExample)
DK (1) DK3383916T3 (enExample)
EA (1) EA201991099A1 (enExample)
ES (1) ES2908662T3 (enExample)
HR (1) HRP20220629T1 (enExample)
HU (1) HUE058975T2 (enExample)
IL (3) IL267942B (enExample)
LT (1) LT3383916T (enExample)
MX (1) MX391656B (enExample)
MY (1) MY188386A (enExample)
NZ (1) NZ753714A (enExample)
PE (1) PE20191208A1 (enExample)
PH (1) PH12019550087A1 (enExample)
PL (1) PL3383916T3 (enExample)
PT (1) PT3383916T (enExample)
RS (1) RS63195B1 (enExample)
SI (1) SI3383916T1 (enExample)
UA (1) UA126571C2 (enExample)
WO (1) WO2018137598A1 (enExample)
ZA (1) ZA201904619B (enExample)

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BR112019007369A2 (pt) 2016-10-11 2019-07-16 Agenus Inc anticorpos anti-lag-3 e métodos de uso dos mesmos
CR20230030A (es) 2018-02-27 2023-03-10 Incyte Corp Imidazopirimidinas y triazolopirimidinas como inhibidores de a2a / a2b (divisional 2020-0441)
JP7319992B2 (ja) 2018-03-09 2023-08-02 アジェナス インコーポレイテッド 抗ｃｄ７３抗体およびそれらの使用方法
MX2020012376A (es) 2018-05-18 2021-03-09 Incyte Corp Derivados de pirimidina fusionados como inhibidores de los receptores de adenosina a2a/a2b.
MX2021000116A (es) 2018-07-05 2021-03-29 Incyte Corp Derivados de pirazina fusionados como inhibidores de a2a/a2b.
WO2020020307A1 (en) * 2018-07-25 2020-01-30 I-Mab Biopharma Co., Ltd. Anti-cd73 anti-pd-l1 bispecific antibodies
CN112513089A (zh) * 2018-11-12 2021-03-16 江苏恒瑞医药股份有限公司 抗cd73抗体、其抗原结合片段及应用
CN111499747B (zh) * 2019-01-11 2022-03-18 康诺亚生物医药科技（成都）有限公司 一种抗cd73单克隆抗体及其应用
CN111434688A (zh) * 2019-01-11 2020-07-21 上海开拓者生物医药有限公司 Cd73抗体及其制备方法和应用
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