CN1806047A - 新型腈水合酶 - Google Patents

新型腈水合酶 Download PDF

Info

Publication number
CN1806047A
CN1806047A CNA2004800161703A CN200480016170A CN1806047A CN 1806047 A CN1806047 A CN 1806047A CN A2004800161703 A CNA2004800161703 A CN A2004800161703A CN 200480016170 A CN200480016170 A CN 200480016170A CN 1806047 A CN1806047 A CN 1806047A
Authority
CN
China
Prior art keywords
subunit
dna
activity
nitrile hydratase
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2004800161703A
Other languages
English (en)
Chinese (zh)
Inventor
古家加夫留
玉木彰
长泽伸一郎
铃木绫乃
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Corp
Original Assignee
Asahi Kasei Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Kasei Kogyo KK filed Critical Asahi Kasei Kogyo KK
Publication of CN1806047A publication Critical patent/CN1806047A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/01084—Nitrile hydratase (4.2.1.84)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CNA2004800161703A 2003-06-10 2004-06-10 新型腈水合酶 Pending CN1806047A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP164773/2003 2003-06-10
JP2003164773 2003-06-10

Publications (1)

Publication Number Publication Date
CN1806047A true CN1806047A (zh) 2006-07-19

Family

ID=33508825

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2004800161703A Pending CN1806047A (zh) 2003-06-10 2004-06-10 新型腈水合酶

Country Status (6)

Country Link
JP (1) JP4108095B2 (ja)
KR (1) KR100806991B1 (ja)
CN (1) CN1806047A (ja)
AU (1) AU2004245849B2 (ja)
TW (1) TW200504211A (ja)
WO (1) WO2004108942A1 (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106459962A (zh) * 2014-06-06 2017-02-22 三菱丽阳株式会社 改良型腈水合酶
CN107075494A (zh) * 2014-09-30 2017-08-18 巴斯夫欧洲公司 制备具有较少丙烯酸的酰胺化合物的手段和方法
CN111334495A (zh) * 2020-03-12 2020-06-26 东莞市东阳光生物合成药有限公司 制备右旋酰胺酮洛芬的方法
CN113444714A (zh) * 2021-07-29 2021-09-28 浙江大学杭州国际科创中心 一种β亚基突变的腈水合酶突变体及其应用

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200634151A (en) * 2004-12-09 2006-10-01 Asahi Chemical Ind Transformant expressing nitrile hydratase
JP2007181404A (ja) * 2005-12-29 2007-07-19 Institute Of Physical & Chemical Research イソニトリル加水分解酵素、およびアミンの製造方法
JP5120852B2 (ja) * 2006-07-06 2013-01-16 国立大学法人 筑波大学 新規タンパク質複合体、該タンパク質複合体を用いたコバルト型低分子量ニトリルヒドラターゼ成熟化方法、成熟化コバルト型低分子量ニトリルヒドラターゼ、及び該ニトリルヒドラターゼを用いた方法
JP5080787B2 (ja) * 2006-11-15 2012-11-21 達彦 小林 タンパク質改変方法、ニトリルヒドラターゼ成熟化方法、成熟化ニトリルヒドラターゼ生産方法、成熟化ニトリルヒドラターゼを用いたアミド化合物生産方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6153415A (en) * 1998-04-29 2000-11-28 Board Of Trustees Operating Michigan State University Method for producing amide compounds using a nitrile hydratase from a thermophilic bacillus

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106459962A (zh) * 2014-06-06 2017-02-22 三菱丽阳株式会社 改良型腈水合酶
CN107075494A (zh) * 2014-09-30 2017-08-18 巴斯夫欧洲公司 制备具有较少丙烯酸的酰胺化合物的手段和方法
CN107075494B (zh) * 2014-09-30 2021-11-23 巴斯夫欧洲公司 制备具有较少丙烯酸的酰胺化合物的手段和方法
CN111334495A (zh) * 2020-03-12 2020-06-26 东莞市东阳光生物合成药有限公司 制备右旋酰胺酮洛芬的方法
CN111334495B (zh) * 2020-03-12 2022-04-29 宜昌东阳光生化制药有限公司 制备右旋酰胺酮洛芬的方法
CN113444714A (zh) * 2021-07-29 2021-09-28 浙江大学杭州国际科创中心 一种β亚基突变的腈水合酶突变体及其应用

Also Published As

Publication number Publication date
AU2004245849B2 (en) 2008-10-09
JPWO2004108942A1 (ja) 2006-07-20
KR20060016115A (ko) 2006-02-21
KR100806991B1 (ko) 2008-02-25
TW200504211A (en) 2005-02-01
TWI321151B (ja) 2010-03-01
JP4108095B2 (ja) 2008-06-25
AU2004245849A1 (en) 2004-12-16
WO2004108942A1 (ja) 2004-12-16

Similar Documents

Publication Publication Date Title
CN100347291C (zh) 用于发酵制备l－半胱氨酸、l－胱氨酸、n－乙酰丝氨酸或四氢噻唑衍生物的微生物和方法
CN1260363C (zh) 由腈化合物生产酰胺的方法
CN1198919C (zh) 经过发酵生产l－丝氨酸的方法
CN1155711C (zh) 制备o-乙酰丝氨酸和l-半胱氨酸以及l-半胱氨酸相关产物的方法
CN1040025C (zh) 编码可提高耐热性的脱氨基甲酰酶的dna及其用途
CN101044243A (zh) 类异戊二烯的生产方法
CN1961072A (zh) 改良型腈水合酶
CN1295343C (zh) L－谷氨酸的制备方法
CN1530438A (zh) 使用利用甲醇的细菌生产l-赖氨酸的方法
CN1908174A (zh) 生产l－赖氨酸的方法
CN1729288A (zh) 新型腈水合酶
CN1636055A (zh) 分离和表达敏捷食酸菌72w的腈水解酶基因
CN1571843A (zh) 腈水合酶和生产酰胺的方法
CN1253177A (zh) 生产微生物转谷氨酰胺酶的方法
CN101040047A (zh) 编码新型的具有d－丝氨酸合成活性的酶的dna、该酶的制备方法、及利用该酶的d－丝氨酸制备方法
CN1833028A (zh) 制备l－苏氨酸的方法
CN1763200A (zh) 产l－谷氨酸细菌和生产l－谷氨酸的方法
CN1806047A (zh) 新型腈水合酶
CN1224697C (zh) 氨基醇及其衍生物的制备方法
CN1650006A (zh) 葡萄糖脱氢酶β亚基及其编码DNA
CN1916164A (zh) 生产D－N－氨基甲酰基－α－氨基酸的方法
CN1891820A (zh) 在表面活性剂存在下稳定的胆固醇氧化酶
CN1639328A (zh) 新型脱氢酶和编码该脱氢酶的基因
CN1572878A (zh) L－氨基酸的生产方法
CN1934250A (zh) 新的醇脱氢酶

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication