CN1794991A - 含有组蛋白脱乙酰酶抑制剂的药物组合物 - Google Patents

含有组蛋白脱乙酰酶抑制剂的药物组合物 Download PDF

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Publication number
CN1794991A
CN1794991A CNA2004800146332A CN200480014633A CN1794991A CN 1794991 A CN1794991 A CN 1794991A CN A2004800146332 A CNA2004800146332 A CN A2004800146332A CN 200480014633 A CN200480014633 A CN 200480014633A CN 1794991 A CN1794991 A CN 1794991A
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China
Prior art keywords
cancer
group
drug regimen
combination
described composition
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Pending
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CNA2004800146332A
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English (en)
Chinese (zh)
Inventor
中西理
菅原达朗
右田秀幸
松叶康浩
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Merck Sharp and Dohme LLC
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Schering Corp
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Publication of CN1794991A publication Critical patent/CN1794991A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CNA2004800146332A 2003-05-26 2004-05-26 含有组蛋白脱乙酰酶抑制剂的药物组合物 Pending CN1794991A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP148073/2003 2003-05-26
JP2003148073 2003-05-26

Related Child Applications (1)

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CNA2008101007303A Division CN101322707A (zh) 2003-05-26 2004-05-26 含有组蛋白脱乙酰酶抑制剂的药物组合物

Publications (1)

Publication Number Publication Date
CN1794991A true CN1794991A (zh) 2006-06-28

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ID=33475383

Family Applications (2)

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CNA2004800146332A Pending CN1794991A (zh) 2003-05-26 2004-05-26 含有组蛋白脱乙酰酶抑制剂的药物组合物
CNA2008101007303A Pending CN101322707A (zh) 2003-05-26 2004-05-26 含有组蛋白脱乙酰酶抑制剂的药物组合物

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CNA2008101007303A Pending CN101322707A (zh) 2003-05-26 2004-05-26 含有组蛋白脱乙酰酶抑制剂的药物组合物

Country Status (27)

Country Link
US (1) US20070098816A1 (https=)
EP (1) EP1626719A1 (https=)
JP (1) JP2006526031A (https=)
KR (1) KR100938712B1 (https=)
CN (2) CN1794991A (https=)
AR (1) AR045318A1 (https=)
AU (1) AU2004241873C1 (https=)
BR (1) BRPI0410959A (https=)
CA (4) CA2634766A1 (https=)
CL (1) CL2004001278A1 (https=)
CO (1) CO5660262A2 (https=)
CR (1) CR8163A (https=)
CU (1) CU23490B7 (https=)
EC (1) ECSP056253A (https=)
IL (1) IL171941A0 (https=)
ME (1) MEP32308A (https=)
MX (1) MXPA05012345A (https=)
NO (1) NO20055417L (https=)
NZ (1) NZ543591A (https=)
PE (1) PE20050206A1 (https=)
RS (1) RS20050884A (https=)
RU (1) RU2322971C2 (https=)
TW (1) TW200505424A (https=)
UA (1) UA81499C2 (https=)
UY (1) UY28330A1 (https=)
WO (1) WO2004103369A1 (https=)
ZA (1) ZA200509515B (https=)

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ES2921576T3 (es) 2008-12-19 2022-08-29 Vertex Pharma Compuestos útiles como inhibidores de la quinasa ATR
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Also Published As

Publication number Publication date
MEP32308A (en) 2010-10-10
PE20050206A1 (es) 2005-03-26
CA2634766A1 (en) 2004-12-02
AU2004241873C1 (en) 2009-01-22
KR20060009371A (ko) 2006-01-31
TW200505424A (en) 2005-02-16
RU2322971C2 (ru) 2008-04-27
ECSP056253A (es) 2006-10-25
NO20055417D0 (no) 2005-11-16
UA81499C2 (en) 2008-01-10
CL2004001278A1 (es) 2005-05-06
KR100938712B1 (ko) 2010-01-25
MXPA05012345A (es) 2006-02-08
US20070098816A1 (en) 2007-05-03
EP1626719A1 (en) 2006-02-22
RS20050884A (sr) 2008-04-04
AU2004241873A1 (en) 2004-12-02
AU2004241873B8 (en) 2008-05-29
IL171941A0 (en) 2006-04-10
RU2005140570A (ru) 2006-06-10
BRPI0410959A (pt) 2006-07-04
ZA200509515B (en) 2006-07-26
CA2634709A1 (en) 2004-12-02
WO2004103369A1 (en) 2004-12-02
CU23490B7 (es) 2010-02-23
CA2527191A1 (en) 2004-12-02
CO5660262A2 (es) 2006-07-31
UY28330A1 (es) 2004-12-31
CN101322707A (zh) 2008-12-17
CR8163A (es) 2006-07-14
JP2006526031A (ja) 2006-11-16
CA2634765A1 (en) 2004-12-02
AR045318A1 (es) 2005-10-26
AU2004241873B2 (en) 2008-05-08
NO20055417L (no) 2005-12-19
NZ543591A (en) 2009-09-25

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Open date: 20060628