CN1761491A - 止血材料 - Google Patents
止血材料 Download PDFInfo
- Publication number
- CN1761491A CN1761491A CNA2004800075093A CN200480007509A CN1761491A CN 1761491 A CN1761491 A CN 1761491A CN A2004800075093 A CNA2004800075093 A CN A2004800075093A CN 200480007509 A CN200480007509 A CN 200480007509A CN 1761491 A CN1761491 A CN 1761491A
- Authority
- CN
- China
- Prior art keywords
- thrombin
- woven fabric
- factor
- synthesis
- biology
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
- A61F13/36—Surgical swabs, e.g. for absorbency or packing body cavities during surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00365—Plasters use
- A61F2013/00463—Plasters use haemostatic
- A61F2013/00472—Plasters use haemostatic with chemical means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/04—Materials for stopping bleeding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
- Y10T442/20—Coated or impregnated woven, knit, or nonwoven fabric which is not [a] associated with another preformed layer or fiber layer or, [b] with respect to woven and knit, characterized, respectively, by a particular or differential weave or knit, wherein the coating or impregnation is neither a foamed material nor a free metal or alloy layer
- Y10T442/2508—Coating or impregnation absorbs chemical material other than water
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
- Y10T442/20—Coated or impregnated woven, knit, or nonwoven fabric which is not [a] associated with another preformed layer or fiber layer or, [b] with respect to woven and knit, characterized, respectively, by a particular or differential weave or knit, wherein the coating or impregnation is neither a foamed material nor a free metal or alloy layer
- Y10T442/2525—Coating or impregnation functions biologically [e.g., insect repellent, antiseptic, insecticide, bactericide, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
- Y10T442/20—Coated or impregnated woven, knit, or nonwoven fabric which is not [a] associated with another preformed layer or fiber layer or, [b] with respect to woven and knit, characterized, respectively, by a particular or differential weave or knit, wherein the coating or impregnation is neither a foamed material nor a free metal or alloy layer
- Y10T442/2861—Coated or impregnated synthetic organic fiber fabric
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
- Y10T442/60—Nonwoven fabric [i.e., nonwoven strand or fiber material]
- Y10T442/696—Including strand or fiber material which is stated to have specific attributes [e.g., heat or fire resistance, chemical or solvent resistance, high absorption for aqueous compositions, water solubility, heat shrinkability, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Surgery (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Description
组别 | 出血部位数量 | 止血次数 | ||
第1次 | 第2次 | 第3次 | ||
1 | 7 | 7 | 0 | 0 |
2 | 7 | 6 | 1 | 0 |
3 | 7 | 2 | 3 | 2 |
组别 | 出血部位数量 | 止血次数 | 止血处理后的总出血量(g/5分钟×止血处理次数) | ||
第1次 | 第2次 | 第3次 | |||
1 | 7 | 7 | 0 | 0 | 0.05±0.033 |
2 | 5 | 5 | 0 | 0 | 0.11±0.055 |
3 | 5 | 0 | 3 | 2* | 6.41±5.736 |
Claims (34)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP010494/2003 | 2003-01-20 | ||
JP2003010494 | 2003-01-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1761491A true CN1761491A (zh) | 2006-04-19 |
CN100506290C CN100506290C (zh) | 2009-07-01 |
Family
ID=32767256
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB2004800075093A Expired - Fee Related CN100506290C (zh) | 2003-01-20 | 2004-01-16 | 止血材料 |
Country Status (9)
Country | Link |
---|---|
US (1) | US20060051340A1 (zh) |
EP (1) | EP1588722A4 (zh) |
JP (1) | JP4769578B2 (zh) |
KR (1) | KR101213460B1 (zh) |
CN (1) | CN100506290C (zh) |
AU (1) | AU2004206150B2 (zh) |
CA (1) | CA2513319C (zh) |
IL (1) | IL169768A (zh) |
WO (1) | WO2004064878A1 (zh) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107580605A (zh) * | 2015-05-11 | 2018-01-12 | 哈莫斯塔蒂斯有限公司 | 止血材料 |
CN111278478A (zh) * | 2017-10-27 | 2020-06-12 | 美敦力公司 | 用于锚固植入式医疗装置的套件 |
CN112891610A (zh) * | 2021-01-25 | 2021-06-04 | 上海利康瑞生物工程有限公司 | 猪源纤维蛋白-静电纺丝纳米纤维抗菌止血贴剂及制备方法 |
CN115154649A (zh) * | 2022-06-07 | 2022-10-11 | 湖南工业大学 | 一种新型止血凝胶及其制备方法 |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
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AU2003280730B2 (en) * | 2002-11-14 | 2010-04-29 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Thrombin-carrying bioabsorbable synthetic nonwoven fabric |
CA2567297A1 (en) * | 2004-05-21 | 2005-12-01 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Tissue sealant |
JPWO2006025150A1 (ja) * | 2004-08-30 | 2008-07-31 | 国立大学法人 新潟大学 | 欠損部閉塞用デバイス、欠損部閉塞キット及びその使用方法 |
DK1809342T3 (en) | 2004-10-20 | 2015-08-17 | Ethicon Inc | absorbable hemostat |
US9358318B2 (en) | 2004-10-20 | 2016-06-07 | Ethicon, Inc. | Method of making a reinforced absorbable multilayered hemostatic wound dressing |
US20060258995A1 (en) * | 2004-10-20 | 2006-11-16 | Pendharkar Sanyog M | Method for making a reinforced absorbable multilayered fabric for use in medical devices |
JP2006345745A (ja) * | 2005-06-15 | 2006-12-28 | Juntendo | 肝癌非ヒト動物モデルの作製方法 |
CA2649081A1 (en) * | 2006-04-10 | 2007-10-18 | Ethicon, Inc. | A reinforced absorbable multilayered hemostatic wound dressing and method of making |
US20080095830A1 (en) * | 2006-10-20 | 2008-04-24 | Van Holten Robert W | Method for making a dressing |
US7628066B2 (en) | 2007-02-22 | 2009-12-08 | Ethicon, Inc. | Apparatus and method for evaluating peel adhesion |
KR20090122279A (ko) * | 2007-03-22 | 2009-11-26 | 자이단호진 가가쿠오요비겟세이료호겐쿠쇼 | 고체상 피브리노겐 제제 |
US20100239560A1 (en) * | 2007-04-20 | 2010-09-23 | Jens Hassingboe | Multi component non-woven |
EP2219572A4 (en) * | 2007-12-06 | 2014-05-28 | Nanosys Inc | RESORBABLE HEMOSTATIC STRUCTURES ENHANCED BY NANOMATERIAL AND BANDING MATERIALS |
US8319002B2 (en) | 2007-12-06 | 2012-11-27 | Nanosys, Inc. | Nanostructure-enhanced platelet binding and hemostatic structures |
US8629314B2 (en) | 2007-12-18 | 2014-01-14 | Ethicon, Inc. | Surgical barriers having adhesion inhibiting properties |
US8299316B2 (en) | 2007-12-18 | 2012-10-30 | Ethicon, Inc. | Hemostatic device |
JP5192254B2 (ja) * | 2008-02-08 | 2013-05-08 | 一般財団法人化学及血清療法研究所 | シート状組織接着剤 |
JP2010069031A (ja) * | 2008-09-19 | 2010-04-02 | Chemo Sero Therapeut Res Inst | シート状フィブリン糊接着剤 |
WO2010143711A1 (ja) * | 2009-06-11 | 2010-12-16 | 一般財団法人化学及血清療法研究所 | 創傷被覆材 |
KR101129419B1 (ko) * | 2009-08-11 | 2012-03-26 | 이희영 | 지방조직 및 혈액성분을 이용한 필러 및 이의 제조방법 |
US8329211B2 (en) * | 2010-05-17 | 2012-12-11 | Ethicon, Inc. | Reinforced absorbable multi-layered fabric for hemostatic applications |
US8273369B2 (en) * | 2010-05-17 | 2012-09-25 | Ethicon, Inc. | Reinforced absorbable synthetic matrix for hemostatic applications |
WO2012011429A1 (ja) | 2010-07-20 | 2012-01-26 | 一般財団法人化学及血清療法研究所 | 組織接着用シート製剤 |
MY173719A (en) | 2012-05-14 | 2020-02-18 | Teijin Pharma Ltd | Formed sheet product and hemostatic material |
WO2014145271A1 (en) * | 2013-03-15 | 2014-09-18 | Stb, Ltd. | Compositions having cylindrical volume, methods, and applicators for sealing injuries |
KR101733865B1 (ko) | 2015-06-26 | 2017-05-10 | 금오공과대학교 산학협력단 | 전기방사형 고분자 섬유를 포함하는 지혈재 및 그 제조방법 |
KR20170025011A (ko) * | 2015-08-27 | 2017-03-08 | 고려대학교 산학협력단 | 통증완화약물의 지속성 방출을 위한 약학적 조성물 및 그 투여를 위한 투여 장치 |
KR102576293B1 (ko) | 2015-11-06 | 2023-09-08 | 에디컨인코포레이티드 | 압밀된 지혈 셀룰로오스 집합체 |
CN107754005B (zh) | 2016-08-15 | 2021-06-15 | 广州倍绣生物技术有限公司 | 止血组合物及其制造方法 |
US11413335B2 (en) | 2018-02-13 | 2022-08-16 | Guangzhou Bioseal Biotech Co. Ltd | Hemostatic compositions and methods of making thereof |
CN107412842B (zh) * | 2017-04-28 | 2020-05-05 | 广东泰宝医疗科技股份有限公司 | 一种带凝血酶的海藻酸盐伤口敷贴的制备方法 |
WO2019107887A2 (ko) * | 2017-11-28 | 2019-06-06 | (주)다림티센 | 지혈용 조성물 및 이를 포함하는 용기 |
KR101989054B1 (ko) * | 2017-11-28 | 2019-06-13 | (주)다림티센 | 지혈용 조성물 및 이를 포함하는 용기 |
KR102093839B1 (ko) * | 2019-05-28 | 2020-05-04 | (주)다림티센 | 지혈용 조성물 및 이를 포함하는 용기 |
US11885735B2 (en) | 2019-09-13 | 2024-01-30 | Ethicon, Inc. | Ex vivo and in vivo systems for evaluating hemostatic patches, sealants, adhesives on solid organs |
US11666682B2 (en) * | 2020-08-31 | 2023-06-06 | Ethicon, Inc. | Method of stopping CSF leaks and apparatus therefor |
BR112023004691A2 (pt) | 2020-09-16 | 2023-05-09 | Tissue Link Aps | Um sistema para melhorar o controle hemostático |
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US3937223A (en) * | 1974-04-19 | 1976-02-10 | American Cyanamid Company | Compacted surgical hemostatic felt |
US4265233A (en) * | 1978-04-12 | 1981-05-05 | Unitika Ltd. | Material for wound healing |
DE3105624A1 (de) * | 1981-02-16 | 1982-09-02 | Hormon-Chemie München GmbH, 8000 München | Material zum abdichten und heilen von wunden |
CA1322262C (en) * | 1987-06-26 | 1993-09-21 | Yoshito Ikada | Artificial skin |
JP2962606B2 (ja) * | 1991-09-21 | 1999-10-12 | グンゼ株式会社 | 医療用補綴材 |
US5393594A (en) * | 1993-10-06 | 1995-02-28 | United States Surgical Corporation | Absorbable non-woven fabric |
JP3795100B2 (ja) * | 1995-05-08 | 2006-07-12 | 株式会社伊垣医療設計 | 医療用縫合材 |
CA2245585A1 (en) * | 1996-02-06 | 1997-08-14 | David P. Kosow | Composition for sealing wounds |
CZ318998A3 (cs) * | 1996-04-04 | 1999-09-15 | Baxter Aktiengesellschaft | Hemostatická houba na bázi kolagenu, způsob její přípravy, kryt na ránu a kit k přípravě tohoto krytu |
EP0993311B1 (en) * | 1997-06-18 | 2012-11-14 | Angiotech Pharmaceuticals (US), Inc. | Compositions containing thrombin and microfibrillar collagen, and methods for preparation and use thereof |
US6056970A (en) * | 1998-05-07 | 2000-05-02 | Genzyme Corporation | Compositions comprising hemostatic compounds and bioabsorbable polymers |
AU755486B2 (en) * | 1998-05-19 | 2002-12-12 | American National Red Cross, The | Hemostatic sandwich bandage |
ES2183606T5 (es) * | 1998-12-23 | 2008-05-16 | Csl Behring Gmbh | Granulado de adhesivo de fibrina y procedimiento para su preparacion. |
AR032800A1 (es) * | 2001-01-25 | 2003-11-26 | Nycomed Pharma As | Una suspension que comprende fibrinogeno, trombina y alcohol, un metodo para preparar dicha suspension, un metodo para recubrir un agente con dicha suspension, y un metodo para secar un recubrimiento de un agente, y una esponja de colageno recubierta |
JP4863417B2 (ja) * | 2001-04-23 | 2012-01-25 | タキロン株式会社 | 生体内分解吸収性不織布及びその製造方法 |
CA2512659A1 (en) * | 2004-02-13 | 2005-08-13 | The Procter & Gamble Company | Discoloration-resistant articles for applying color on surfaces and methods of reducing discoloration in articles for applying color on surfaces |
-
2004
- 2004-01-16 EP EP04702784A patent/EP1588722A4/en not_active Withdrawn
- 2004-01-16 WO PCT/JP2004/000291 patent/WO2004064878A1/ja active Application Filing
- 2004-01-16 JP JP2005508046A patent/JP4769578B2/ja not_active Expired - Fee Related
- 2004-01-16 AU AU2004206150A patent/AU2004206150B2/en not_active Ceased
- 2004-01-16 CN CNB2004800075093A patent/CN100506290C/zh not_active Expired - Fee Related
- 2004-01-16 US US10/542,577 patent/US20060051340A1/en not_active Abandoned
- 2004-01-16 CA CA2513319A patent/CA2513319C/en not_active Expired - Fee Related
- 2004-01-16 KR KR1020057013303A patent/KR101213460B1/ko active IP Right Grant
-
2005
- 2005-07-19 IL IL16976805A patent/IL169768A/en active IP Right Grant
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107580605A (zh) * | 2015-05-11 | 2018-01-12 | 哈莫斯塔蒂斯有限公司 | 止血材料 |
CN111278478A (zh) * | 2017-10-27 | 2020-06-12 | 美敦力公司 | 用于锚固植入式医疗装置的套件 |
CN112891610A (zh) * | 2021-01-25 | 2021-06-04 | 上海利康瑞生物工程有限公司 | 猪源纤维蛋白-静电纺丝纳米纤维抗菌止血贴剂及制备方法 |
CN115154649A (zh) * | 2022-06-07 | 2022-10-11 | 湖南工业大学 | 一种新型止血凝胶及其制备方法 |
Also Published As
Publication number | Publication date |
---|---|
JP4769578B2 (ja) | 2011-09-07 |
KR20050100626A (ko) | 2005-10-19 |
CN100506290C (zh) | 2009-07-01 |
WO2004064878A1 (ja) | 2004-08-05 |
AU2004206150A1 (en) | 2004-08-05 |
AU2004206150B2 (en) | 2009-10-29 |
IL169768A (en) | 2014-01-30 |
US20060051340A1 (en) | 2006-03-09 |
AU2004206150A8 (en) | 2004-08-05 |
CA2513319A1 (en) | 2004-08-05 |
CA2513319C (en) | 2013-03-19 |
EP1588722A1 (en) | 2005-10-26 |
JPWO2004064878A1 (ja) | 2006-05-18 |
KR101213460B1 (ko) | 2012-12-20 |
EP1588722A4 (en) | 2011-03-02 |
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