CN1635896A - 包含用于治疗癌症及感染性疾病的热休克蛋白或α2-巨球蛋白的组合物制备方法 - Google Patents

包含用于治疗癌症及感染性疾病的热休克蛋白或α2-巨球蛋白的组合物制备方法 Download PDF

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Publication number
CN1635896A
CN1635896A CNA028208250A CN02820825A CN1635896A CN 1635896 A CN1635896 A CN 1635896A CN A028208250 A CNA028208250 A CN A028208250A CN 02820825 A CN02820825 A CN 02820825A CN 1635896 A CN1635896 A CN 1635896A
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Prior art keywords
antigenic
proteins
protein
complex
cells
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CNA028208250A
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English (en)
Chinese (zh)
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P·K·斯里瓦斯塔瓦
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University of Connecticut Health Center
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University of Connecticut Health Center
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Publication of CN1635896A publication Critical patent/CN1635896A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6043Heat shock proteins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CNA028208250A 2001-08-20 2002-08-20 包含用于治疗癌症及感染性疾病的热休克蛋白或α2-巨球蛋白的组合物制备方法 Pending CN1635896A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US31362901P 2001-08-20 2001-08-20
US60/313,629 2001-08-20
US33722201P 2001-12-06 2001-12-06
US60/337,222 2001-12-06

Publications (1)

Publication Number Publication Date
CN1635896A true CN1635896A (zh) 2005-07-06

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CNA028208250A Pending CN1635896A (zh) 2001-08-20 2002-08-20 包含用于治疗癌症及感染性疾病的热休克蛋白或α2-巨球蛋白的组合物制备方法

Country Status (12)

Country Link
US (1) US7666581B2 (enExample)
EP (1) EP1536829A4 (enExample)
JP (1) JP4384489B2 (enExample)
KR (1) KR20040064688A (enExample)
CN (1) CN1635896A (enExample)
AU (1) AU2002335654B2 (enExample)
CA (1) CA2457008A1 (enExample)
HK (1) HK1079705A1 (enExample)
IL (1) IL160511A0 (enExample)
PL (1) PL375043A1 (enExample)
RU (2) RU2335295C2 (enExample)
WO (1) WO2003015712A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115896044A (zh) * 2022-11-07 2023-04-04 江苏省农业科学院 一种高效的猪流行性腹泻病毒纯化方法

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CN1764375A (zh) * 2003-02-20 2006-04-26 康涅狄格大学健康中心 使用包括热休克蛋白或α-2-巨球蛋白的组合物治疗癌症和传染病的方法
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AU2013222414B2 (en) 2012-02-21 2018-02-15 Cytonics Corporation Systems, compositions, and methods for transplantation
CN103372209B (zh) * 2012-04-24 2014-09-17 中国科学院微生物研究所 gp96蛋白的抗体在制备癌细胞抑制剂中的应用
JP6678676B2 (ja) 2014-09-15 2020-04-08 オーファザイム エー/エス アリモクロモル製剤
SG11201705844SA (en) * 2015-02-06 2017-08-30 Heat Biologics Inc Vector co-expressing vaccine and costimulatory molecules
IL293135A (en) 2015-05-13 2022-07-01 Agenus Inc Composition comprising at least two different complexes of a purified stress protein bound to an antigenic peptide
US10898476B2 (en) 2016-04-13 2021-01-26 Orphazyme A/S Heat shock proteins and cholesterol homeostasis
BR112018070653A2 (pt) 2016-04-29 2019-02-05 Orphazyme As ingrediente farmacêutico ativo, e, composição
RU2640017C1 (ru) * 2016-10-31 2017-12-25 Алла Анатольевна Ляшенко Способ получения биологического материала для создания аутологичных противоопухолевых вакцин
JP2021522239A (ja) 2018-04-26 2021-08-30 アジェナス インコーポレイテッド 熱ショックタンパク質結合ペプチド組成物およびその使用方法
AU2021380947C1 (en) 2020-11-19 2025-02-20 Zevra Denmark A/S Processes for preparing arimoclomol citrate and intermediates thereof

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115896044A (zh) * 2022-11-07 2023-04-04 江苏省农业科学院 一种高效的猪流行性腹泻病毒纯化方法

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WO2003015712A2 (en) 2003-02-27
CA2457008A1 (en) 2003-02-27
RU2335295C2 (ru) 2008-10-10
AU2002335654B2 (en) 2008-02-21
JP2005511495A (ja) 2005-04-28
US7666581B2 (en) 2010-02-23
HK1079705A1 (zh) 2006-04-13
US20030129196A1 (en) 2003-07-10
WO2003015712A3 (en) 2005-04-14
RU2008120299A (ru) 2009-11-27
IL160511A0 (en) 2004-07-25
KR20040064688A (ko) 2004-07-19
EP1536829A4 (en) 2006-05-31
PL375043A1 (en) 2005-11-14
JP4384489B2 (ja) 2009-12-16
RU2004108129A (ru) 2005-04-20
EP1536829A2 (en) 2005-06-08

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