EP0851765A4 - Therapeutic and prophylactic methods using heat shock proteins - Google Patents
Therapeutic and prophylactic methods using heat shock proteinsInfo
- Publication number
- EP0851765A4 EP0851765A4 EP96930818A EP96930818A EP0851765A4 EP 0851765 A4 EP0851765 A4 EP 0851765A4 EP 96930818 A EP96930818 A EP 96930818A EP 96930818 A EP96930818 A EP 96930818A EP 0851765 A4 EP0851765 A4 EP 0851765A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- therapeutic
- heat shock
- shock proteins
- prophylactic methods
- prophylactic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 102000002812 Heat-Shock Proteins Human genes 0.000 title 1
- 108010004889 Heat-Shock Proteins Proteins 0.000 title 1
- 230000000069 prophylactic effect Effects 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001176—Heat shock proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6043—Heat shock proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/622—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier non-covalent binding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US527547 | 1995-09-13 | ||
US08/527,547 US5935576A (en) | 1995-09-13 | 1995-09-13 | Compositions and methods for the treatment and prevention of neoplastic diseases using heat shock proteins complexed with exogenous antigens |
US08/711,918 US6030618A (en) | 1995-09-13 | 1996-09-10 | Therapeutic and prophylactic methods using heat shock proteins |
US711918 | 1996-09-10 | ||
PCT/US1996/014556 WO1997010000A1 (en) | 1995-09-13 | 1996-09-11 | Therapeutic and prophylactic methods using heat shock proteins |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0851765A1 EP0851765A1 (en) | 1998-07-08 |
EP0851765A4 true EP0851765A4 (en) | 2000-01-19 |
Family
ID=27062437
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP96930818A Ceased EP0851765A4 (en) | 1995-09-13 | 1996-09-11 | Therapeutic and prophylactic methods using heat shock proteins |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0851765A4 (en) |
JP (1) | JPH11513369A (en) |
AU (1) | AU727673B2 (en) |
CA (1) | CA2231998A1 (en) |
WO (1) | WO1997010000A1 (en) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6761892B1 (en) | 1995-08-18 | 2004-07-13 | Sloan-Kettering Institute For Cancer Research | Heat shock protein-based vaccines and immunotherapies |
WO1997006821A1 (en) | 1995-08-18 | 1997-02-27 | Sloan-Kettering Institute For Cancer Research | Heat shock protein-based vaccines and immunotherapies |
US6773707B1 (en) | 1995-08-18 | 2004-08-10 | Sloan-Kettering Institute For Cancer Research | Heat shock protein-based vaccines and immunotherapies |
US6719974B1 (en) | 1995-08-18 | 2004-04-13 | Sloan-Kettering Institute For Cancer Research | Heat shock protein-based vaccines and immunotherapies |
US6331299B1 (en) | 1995-08-18 | 2001-12-18 | Sloan-Kettering Institute For Cancer Research | Method for treatment of cancer and infectious disease and compositions useful in same |
US6017540A (en) * | 1997-02-07 | 2000-01-25 | Fordham University | Prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with heat shock/stress protein-peptide complexes |
AU2005201826B2 (en) * | 1997-08-05 | 2008-01-17 | Nventa Biopharmaceuticals Corporation | Immune responses against HPV antigens elicited by compositions comprising an HPV antigen and a stress protein or an expression vector capable of expression of these proteins |
DK1002110T3 (en) | 1997-08-05 | 2003-05-26 | Stressgen Biotechnologies Corp | Immune response to HPV antigens induced by compositions comprising an HPV antigen and a stress protein or expression vector capable of expressing these proteins |
EP1336621B1 (en) * | 1997-08-05 | 2006-05-24 | Stressgen Biotechnologies Corporation | Immune responses against HPV antigens elicited by compositions comprising an HPV antigen and a stress protein or an expression vector capable of expression of these proteins |
US5948646A (en) | 1997-12-11 | 1999-09-07 | Fordham University | Methods for preparation of vaccines against cancer comprising heat shock protein-peptide complexes |
ES2439014T3 (en) | 1998-02-20 | 2014-01-21 | The University Of Miami | Complex of antigenic peptide-modified heat shock protein |
US6797480B1 (en) | 1998-10-05 | 2004-09-28 | University Of Connecticut Health Center | Purification of heat shock/stress protein cell surface receptors and their use as immunotherapeutic agents |
GB9919733D0 (en) * | 1999-08-19 | 1999-10-20 | Colaco Camilo | Vaccines against intracellular pathogens |
AUPQ233799A0 (en) | 1999-08-19 | 1999-09-09 | Minister For Agriculture, Minister For Land And Water Conservation For And On Behalf Of The State Of New South Wales | Recombinant sub-unit vaccine |
AU7743100A (en) | 1999-09-30 | 2001-04-30 | Corixa Corporation | Stress protein compositions and methods for prevention and treatment of cancer and infectious disease |
US7378096B2 (en) | 1999-09-30 | 2008-05-27 | Health Research, Inc. | Stress protein compositions and methods for prevention and treatment of cancer and infectious disease |
US7030228B1 (en) | 1999-11-15 | 2006-04-18 | Miltenyi Biotec Gmbh | Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby |
WO2001091787A1 (en) | 2000-06-02 | 2001-12-06 | University Of Connecticut Health Center | Complexes of alpha (2) macroglobulin and antigenic molecules for immunotherapy |
EP1536829A4 (en) * | 2001-08-20 | 2006-05-31 | Univ Connecticut Health Ct | Methods for preparing compositions comprising heat shock proteins or alpha-2-macroglobulin useful for the treatment of cancer and infectious disease |
AU2002327804B2 (en) | 2001-10-01 | 2008-09-11 | Duke University | Three dimensional structure of crystalline GRP94 binding domain, and its methods of use |
EP1572083A4 (en) * | 2002-04-25 | 2008-09-24 | Univ Connecticut Health Ct | Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality |
US7420037B2 (en) | 2003-02-13 | 2008-09-02 | Antigenics Inc. | Heat shock protein-based vaccines and immunotherapies |
ES2385933T3 (en) | 2003-02-20 | 2012-08-03 | University Of Connecticut Health Center | METHODS FOR THE PRODUCTION OF ALFA ANTIGEN MOLECULES COMPLEXES (2) MACROGLOBULIN. |
CA2517396A1 (en) | 2003-02-28 | 2005-03-10 | Antigenics Inc. | Use of lectins to promote oligomerization of glycoproteins and antigenic molecules |
US7309491B2 (en) | 2003-04-11 | 2007-12-18 | Antigenics Inc. | Heat shock protein-based vaccines and immunotherapies |
EP1670507A4 (en) * | 2003-09-12 | 2007-10-17 | Antigenics Inc | Vaccine for treatment and prevention of herpes simplex virus infection |
WO2009114085A2 (en) | 2008-03-03 | 2009-09-17 | The University Of Miami | Allogeneic cancer cell-based immunotherapy |
AU2009226077B2 (en) | 2008-03-20 | 2012-04-19 | University Of Miami | Heat shock protein gp96 vaccination and methods of using same |
AU2010232490B2 (en) | 2009-04-03 | 2016-08-11 | Agenus Inc. | Methods for preparing and using multichaperone-antigen complexes |
GB0910591D0 (en) * | 2009-06-19 | 2009-07-29 | Immunobiology Ltd | Method for the purification of protein complexes |
GB0916557D0 (en) | 2009-09-21 | 2009-10-28 | Health Prot Agency | Commensal neisserial stress protein complexes |
JP6744318B2 (en) | 2015-02-06 | 2020-08-26 | ヒート バイオロジクス,インコーポレイテッド | Vector co-expressing vaccine and costimulatory molecule |
KR20180006945A (en) | 2015-05-13 | 2018-01-19 | 아게누스 인코포레이티드 | Vaccine for cancer treatment and prevention |
WO2018071405A1 (en) | 2016-10-11 | 2018-04-19 | University Of Miami | Vectors and vaccine cells for immunity against zika virus |
US11548930B2 (en) | 2017-04-04 | 2023-01-10 | Heat Biologics, Inc. | Intratumoral vaccination |
AU2019261451A1 (en) | 2018-04-26 | 2020-12-03 | Agenus Inc. | Heat shock protein-binding peptide compositions and methods of use thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993017712A2 (en) * | 1992-03-06 | 1993-09-16 | Biocine Spa | Conjugates formed from heat shock proteins and oligo- or polysaccharides |
WO1994003208A1 (en) * | 1992-07-30 | 1994-02-17 | Yeda Research And Development Company Ltd. | Conjugates of poorly immunogenic antigens and synthetic peptide carriers and vaccines comprising them |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE127345T1 (en) * | 1988-06-15 | 1995-09-15 | Whitehead Biomedical Inst | STRESS PROTEINS AND USES THEREOF. |
-
1996
- 1996-09-11 WO PCT/US1996/014556 patent/WO1997010000A1/en active Application Filing
- 1996-09-11 JP JP9512062A patent/JPH11513369A/en not_active Ceased
- 1996-09-11 AU AU69734/96A patent/AU727673B2/en not_active Ceased
- 1996-09-11 CA CA002231998A patent/CA2231998A1/en not_active Abandoned
- 1996-09-11 EP EP96930818A patent/EP0851765A4/en not_active Ceased
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993017712A2 (en) * | 1992-03-06 | 1993-09-16 | Biocine Spa | Conjugates formed from heat shock proteins and oligo- or polysaccharides |
WO1994003208A1 (en) * | 1992-07-30 | 1994-02-17 | Yeda Research And Development Company Ltd. | Conjugates of poorly immunogenic antigens and synthetic peptide carriers and vaccines comprising them |
Non-Patent Citations (2)
Title |
---|
P. K. SRIVASTAVA ET AL.: "Heat shock protein-peptide complexes in cancer immunotherapy", CURRENT OPINION IN IMMUNOLOGY, vol. 6, 1994, pages 728 - 732, XP002037578 * |
See also references of WO9710000A1 * |
Also Published As
Publication number | Publication date |
---|---|
AU6973496A (en) | 1997-04-01 |
EP0851765A1 (en) | 1998-07-08 |
JPH11513369A (en) | 1999-11-16 |
WO1997010000A1 (en) | 1997-03-20 |
CA2231998A1 (en) | 1997-03-20 |
AU727673B2 (en) | 2000-12-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19980409 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19991208 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
RA4 | Supplementary search report drawn up and despatched (corrected) |
Effective date: 19991208 |
|
17Q | First examination report despatched |
Effective date: 20010326 |
|
17Q | First examination report despatched |
Effective date: 20010326 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED |
|
18R | Application refused |
Effective date: 20080219 |