HK1079705A1 - 包含用於治療癌症及感染性疾病的熱休克蛋白或α2-巨球蛋白的組合物製備方法 - Google Patents
包含用於治療癌症及感染性疾病的熱休克蛋白或α2-巨球蛋白的組合物製備方法Info
- Publication number
- HK1079705A1 HK1079705A1 HK05112097.2A HK05112097A HK1079705A1 HK 1079705 A1 HK1079705 A1 HK 1079705A1 HK 05112097 A HK05112097 A HK 05112097A HK 1079705 A1 HK1079705 A1 HK 1079705A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- macroglobulin
- cancer
- alpha
- useful
- treatment
- Prior art date
Links
- 102100033312 Alpha-2-macroglobulin Human genes 0.000 title 1
- 208000035473 Communicable disease Diseases 0.000 title 1
- 102000002812 Heat-Shock Proteins Human genes 0.000 title 1
- 108010004889 Heat-Shock Proteins Proteins 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 108010015078 Pregnancy-Associated alpha 2-Macroglobulins Proteins 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6043—Heat shock proteins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31362901P | 2001-08-20 | 2001-08-20 | |
US33722201P | 2001-12-06 | 2001-12-06 | |
PCT/US2002/026573 WO2003015712A2 (en) | 2001-08-20 | 2002-08-20 | Methods for preparing compositions comprising heat shock proteins or alpha-2-macroglobulin |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1079705A1 true HK1079705A1 (zh) | 2006-04-13 |
Family
ID=26978972
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK05112097.2A HK1079705A1 (zh) | 2001-08-20 | 2005-12-29 | 包含用於治療癌症及感染性疾病的熱休克蛋白或α2-巨球蛋白的組合物製備方法 |
Country Status (12)
Country | Link |
---|---|
US (1) | US7666581B2 (zh) |
EP (1) | EP1536829A4 (zh) |
JP (1) | JP4384489B2 (zh) |
KR (1) | KR20040064688A (zh) |
CN (1) | CN1635896A (zh) |
AU (1) | AU2002335654B2 (zh) |
CA (1) | CA2457008A1 (zh) |
HK (1) | HK1079705A1 (zh) |
IL (1) | IL160511A0 (zh) |
PL (1) | PL375043A1 (zh) |
RU (2) | RU2335295C2 (zh) |
WO (1) | WO2003015712A2 (zh) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030211971A1 (en) * | 2001-09-17 | 2003-11-13 | Srivastava Pramod K. | Compositions and methods for prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with compositions comprising unfractionated cellular proteins |
WO2004074454A2 (en) * | 2003-02-20 | 2004-09-02 | University Of Connecticut Health Center | Methods and compositions for the treatment of cancer and infectious disease using alpha (2) macroglobulin-antigenic molecule complexes |
KR20050109498A (ko) * | 2003-02-20 | 2005-11-21 | 유니버시티 오브 코네티컷 헬스 센터 | 암 또는 전염병 치료에서 열 충격 단백질 또는알파-2-마크로글로불린을 포함하는 조성물을 사용하는 방법 |
JP2007505147A (ja) | 2003-09-12 | 2007-03-08 | アンティジェニクス インコーポレーテッド | 単純ヘルペスウイルス感染の治療および予防用ワクチン |
WO2005120558A2 (en) * | 2004-05-25 | 2005-12-22 | University Of Connecticut Health Center | Methods for making compositions comprising heat shock proteins or alpha-2-macroglobulin for the treatment of cancer and infectious disease |
US8754094B2 (en) * | 2007-08-15 | 2014-06-17 | The Research Foundation Of State University Of New York | Methods for heat shock protein dependent cancer treatment |
PT2484371E (pt) | 2008-06-26 | 2015-03-03 | Orphazyme Aps | Uso da hsp70 como um regulador da atividade enzimática |
ES2753169T3 (es) | 2010-11-30 | 2020-04-07 | Orphazyme As | Procedimientos para aumentar la actividad intracelular de Hsp70 |
WO2013126587A1 (en) | 2012-02-21 | 2013-08-29 | Cytonics Corporation | Systems, compositions, and methods for transplantation |
CN103372209B (zh) * | 2012-04-24 | 2014-09-17 | 中国科学院微生物研究所 | gp96蛋白的抗体在制备癌细胞抑制剂中的应用 |
BR112017004948A2 (pt) | 2014-09-15 | 2017-12-05 | Orphazyme Aps | formulação farmacêutica. |
DK3253876T3 (da) * | 2015-02-06 | 2021-01-25 | Heat Biologics Inc | Vektor, der co-ekspresserer vaccine og costimulerende molekyler |
CN107847572A (zh) | 2015-05-13 | 2018-03-27 | 艾吉纳斯公司 | 用于癌症治疗和预防的疫苗 |
EP3442530A1 (en) | 2016-04-13 | 2019-02-20 | Orphazyme A/S | Heat shock proteins and cholesterol homeostasis |
RU2750154C2 (ru) | 2016-04-29 | 2021-06-22 | Орфазим А/С | Аримокломол для лечения ассоциированных с глюкоцереброзидазой нарушений |
RU2640017C1 (ru) * | 2016-10-31 | 2017-12-25 | Алла Анатольевна Ляшенко | Способ получения биологического материала для создания аутологичных противоопухолевых вакцин |
JP2021522239A (ja) | 2018-04-26 | 2021-08-30 | アジェナス インコーポレイテッド | 熱ショックタンパク質結合ペプチド組成物およびその使用方法 |
CA3202568A1 (en) | 2020-11-19 | 2022-05-27 | Zevra Denmark A/S | Processes for preparing arimoclomol citrate and intermediates thereof |
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US5985270A (en) | 1995-09-13 | 1999-11-16 | Fordham University | Adoptive immunotherapy using macrophages sensitized with heat shock protein-epitope complexes |
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US6017540A (en) * | 1997-02-07 | 2000-01-25 | Fordham University | Prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with heat shock/stress protein-peptide complexes |
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US5948646A (en) * | 1997-12-11 | 1999-09-07 | Fordham University | Methods for preparation of vaccines against cancer comprising heat shock protein-peptide complexes |
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US6797480B1 (en) * | 1998-10-05 | 2004-09-28 | University Of Connecticut Health Center | Purification of heat shock/stress protein cell surface receptors and their use as immunotherapeutic agents |
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US7179462B2 (en) * | 2000-06-02 | 2007-02-20 | University Of Connecticut Health Center | α (2) macroglobulin receptor as a heat shock protein receptor and uses thereof |
WO2002011669A2 (en) * | 2000-08-07 | 2002-02-14 | Antigenics, Llc | Compositions comprising heat shock proteins or alpha(2)macroglobulin, antigenic molecules and saponins, and methods of use thereof |
US20020052318A1 (en) | 2000-08-25 | 2002-05-02 | Duke University | Adjuvant |
AU2001292674A1 (en) | 2000-09-15 | 2002-04-29 | University Of Connecticut Health Center | Improved formulations using heat shock/stress protein-peptide complexes |
AU2001294560B2 (en) | 2000-09-15 | 2007-06-21 | University Of Connecticut Health Center | Compositions and methods for prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with compositions comprising unfractionated cellular proteins |
US7132109B1 (en) * | 2000-10-20 | 2006-11-07 | University Of Connecticut Health Center | Using heat shock proteins to increase immune response |
US20020172682A1 (en) | 2000-10-20 | 2002-11-21 | University Of Connecticut Health Center | Using heat shock proteins to increase immune response |
US20030211971A1 (en) | 2001-09-17 | 2003-11-13 | Srivastava Pramod K. | Compositions and methods for prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with compositions comprising unfractionated cellular proteins |
JP2006501147A (ja) | 2002-04-25 | 2006-01-12 | ユニバーシティー オブ コネティカット ヘルス センター | 非ワクチン治療法の治療効果を改善するための熱ショックタンパク質の使用 |
CA2485098A1 (en) | 2002-05-02 | 2003-11-13 | University Of Connecticut Health Center | Use of heat shock proteins to enhance efficacy of antibody therapeutics |
KR20050109498A (ko) | 2003-02-20 | 2005-11-21 | 유니버시티 오브 코네티컷 헬스 센터 | 암 또는 전염병 치료에서 열 충격 단백질 또는알파-2-마크로글로불린을 포함하는 조성물을 사용하는 방법 |
-
2002
- 2002-08-20 EP EP02770416A patent/EP1536829A4/en not_active Withdrawn
- 2002-08-20 JP JP2003520673A patent/JP4384489B2/ja not_active Expired - Fee Related
- 2002-08-20 RU RU2004108129/15A patent/RU2335295C2/ru not_active IP Right Cessation
- 2002-08-20 AU AU2002335654A patent/AU2002335654B2/en not_active Ceased
- 2002-08-20 WO PCT/US2002/026573 patent/WO2003015712A2/en active Search and Examination
- 2002-08-20 IL IL16051102A patent/IL160511A0/xx unknown
- 2002-08-20 CN CNA028208250A patent/CN1635896A/zh active Pending
- 2002-08-20 CA CA002457008A patent/CA2457008A1/en not_active Abandoned
- 2002-08-20 PL PL02375043A patent/PL375043A1/xx unknown
- 2002-08-20 KR KR10-2004-7002750A patent/KR20040064688A/ko not_active Application Discontinuation
- 2002-08-20 US US10/225,367 patent/US7666581B2/en not_active Expired - Fee Related
-
2005
- 2005-12-29 HK HK05112097.2A patent/HK1079705A1/zh unknown
-
2008
- 2008-05-21 RU RU2008120299/15A patent/RU2008120299A/ru not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR20040064688A (ko) | 2004-07-19 |
JP2005511495A (ja) | 2005-04-28 |
AU2002335654B2 (en) | 2008-02-21 |
WO2003015712A3 (en) | 2005-04-14 |
CA2457008A1 (en) | 2003-02-27 |
IL160511A0 (en) | 2004-07-25 |
JP4384489B2 (ja) | 2009-12-16 |
PL375043A1 (en) | 2005-11-14 |
RU2008120299A (ru) | 2009-11-27 |
EP1536829A4 (en) | 2006-05-31 |
EP1536829A2 (en) | 2005-06-08 |
CN1635896A (zh) | 2005-07-06 |
RU2004108129A (ru) | 2005-04-20 |
US20030129196A1 (en) | 2003-07-10 |
US7666581B2 (en) | 2010-02-23 |
WO2003015712A2 (en) | 2003-02-27 |
RU2335295C2 (ru) | 2008-10-10 |
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