CN1575182A - 用于治疗和预防疼痛和炎症的含环加氧酶－2选择性抑制剂和硫酸软骨素的组合物 - Google Patents

用于治疗和预防疼痛和炎症的含环加氧酶－2选择性抑制剂和硫酸软骨素的组合物 Download PDF

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Publication number
CN1575182A
CN1575182A CNA028201213A CN02820121A CN1575182A CN 1575182 A CN1575182 A CN 1575182A CN A028201213 A CNA028201213 A CN A028201213A CN 02820121 A CN02820121 A CN 02820121A CN 1575182 A CN1575182 A CN 1575182A
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Prior art keywords
trifluoromethyl
alkyl
phenyl
benzenesulfonamide
methylsulfonyl
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Pending
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CNA028201213A
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Chinese (zh)
Inventor
S·P·普拉斯基
S·昆德尔
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PharMetrix Corp
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PharMetrix Corp
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Publication of CN1575182A publication Critical patent/CN1575182A/zh
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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  • Pain & Pain Management (AREA)
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  • Endocrinology (AREA)
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  • Rheumatology (AREA)
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  • Cardiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
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CNA028201213A 2001-08-14 2002-08-13 用于治疗和预防疼痛和炎症的含环加氧酶－2选择性抑制剂和硫酸软骨素的组合物 Pending CN1575182A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US31221101P 2001-08-14 2001-08-14
US60/312,211 2001-08-14
US10/215,539 US20030114416A1 (en) 2001-08-14 2002-08-09 Method and compositions for the treatment and prevention of pain and inflammation with a cyclooxygenase-2 selective inhibitor and chondroitin sulfate
US10/215,539 2002-08-09

Publications (1)

Publication Number Publication Date
CN1575182A true CN1575182A (zh) 2005-02-02

Family

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Application Number Title Priority Date Filing Date
CNA028201213A Pending CN1575182A (zh) 2001-08-14 2002-08-13 用于治疗和预防疼痛和炎症的含环加氧酶－2选择性抑制剂和硫酸软骨素的组合物

Country Status (12)

Country Link
US (1) US20030114416A1 (enExample)
EP (1) EP1416941A1 (enExample)
JP (1) JP2005501850A (enExample)
KR (1) KR20040047790A (enExample)
CN (1) CN1575182A (enExample)
AU (1) AU2002336344A2 (enExample)
BR (1) BR0211977A (enExample)
CA (1) CA2457452A1 (enExample)
IL (1) IL160087A0 (enExample)
MX (1) MXPA04001397A (enExample)
PL (1) PL368971A1 (enExample)
WO (1) WO2003015799A1 (enExample)

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CN103371349A (zh) * 2012-04-25 2013-10-30 老笃制药株式会社 内服组合物
CN104644665A (zh) * 2014-06-26 2015-05-27 黄心诚 治疗关节炎的药物
CN112870154A (zh) * 2021-02-03 2021-06-01 四川农业大学 兽用复方塞来昔布纳米脂质体凝胶及其制备方法

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US7335384B2 (en) 2006-03-17 2008-02-26 4K Nutripharma International Nutrient compositions for the treatment and prevention of inflammation and disorders associated therewith
EP2182810B1 (en) * 2007-08-03 2017-11-08 Nucitec S.A. de C.V. Compositions and methods for treatment and prevention of osteoarthritis
KR20100099260A (ko) * 2007-12-12 2010-09-10 디에스엠 아이피 어셋츠 비.브이. 염증성 장애의 치료, 병용-치료 또는 예방을 위한 하이드록시티로솔 및 콘드로이틴을 포함하는 조성물
ES2405314T3 (es) * 2008-05-13 2013-05-30 Apharm S.R.L. Composiciones y uso oral de glicosaminoglicanos
FR2969618B1 (fr) * 2010-12-28 2014-05-16 Pf Medicament Procede de preparation de chondroitine sulfate de sodium
ES2468665B1 (es) * 2012-12-14 2015-06-11 Farmalider, S.A. Composición farmacéutica de sulfato de condroitina y celecoxib
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CN104644665A (zh) * 2014-06-26 2015-05-27 黄心诚 治疗关节炎的药物
CN112870154A (zh) * 2021-02-03 2021-06-01 四川农业大学 兽用复方塞来昔布纳米脂质体凝胶及其制备方法
CN112870154B (zh) * 2021-02-03 2022-10-18 四川农业大学 兽用复方塞来昔布纳米脂质体凝胶及其制备方法

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