BR0211977A - Uso de sulfato de condroitina e um inibidor seletivo de cicloxigenase-2, composição farmacêutica e kit - Google Patents

Uso de sulfato de condroitina e um inibidor seletivo de cicloxigenase-2, composição farmacêutica e kit

Info

Publication number
BR0211977A
BR0211977A BR0211977-3A BR0211977A BR0211977A BR 0211977 A BR0211977 A BR 0211977A BR 0211977 A BR0211977 A BR 0211977A BR 0211977 A BR0211977 A BR 0211977A
Authority
BR
Brazil
Prior art keywords
inhibitor
selective cyclooxygenase
chondroitin sulfate
kit
pharmaceutical composition
Prior art date
Application number
BR0211977-3A
Other languages
English (en)
Portuguese (pt)
Inventor
Steven P Pulaski
Susan Kundel
Original Assignee
Pharmacia Corp Global Patent D
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp Global Patent D filed Critical Pharmacia Corp Global Patent D
Publication of BR0211977A publication Critical patent/BR0211977A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/422Oxazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/501Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
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    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
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    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
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    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Organic Chemistry (AREA)
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  • Epidemiology (AREA)
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  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Biotechnology (AREA)
BR0211977-3A 2001-08-14 2002-08-13 Uso de sulfato de condroitina e um inibidor seletivo de cicloxigenase-2, composição farmacêutica e kit BR0211977A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31221101P 2001-08-14 2001-08-14
US10/215,539 US20030114416A1 (en) 2001-08-14 2002-08-09 Method and compositions for the treatment and prevention of pain and inflammation with a cyclooxygenase-2 selective inhibitor and chondroitin sulfate
PCT/US2002/025673 WO2003015799A1 (en) 2001-08-14 2002-08-13 Compositions for the treatment and prevention of pain and inflammation with a cyclooxygenase-2 selective inhibitor and chondroitin sulfate

Publications (1)

Publication Number Publication Date
BR0211977A true BR0211977A (pt) 2004-09-21

Family

ID=26910139

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0211977-3A BR0211977A (pt) 2001-08-14 2002-08-13 Uso de sulfato de condroitina e um inibidor seletivo de cicloxigenase-2, composição farmacêutica e kit

Country Status (12)

Country Link
US (1) US20030114416A1 (enExample)
EP (1) EP1416941A1 (enExample)
JP (1) JP2005501850A (enExample)
KR (1) KR20040047790A (enExample)
CN (1) CN1575182A (enExample)
AU (1) AU2002336344A2 (enExample)
BR (1) BR0211977A (enExample)
CA (1) CA2457452A1 (enExample)
IL (1) IL160087A0 (enExample)
MX (1) MXPA04001397A (enExample)
PL (1) PL368971A1 (enExample)
WO (1) WO2003015799A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7033604B2 (en) * 2001-07-06 2006-04-25 Sucampo Ag Composition for topical administration
ES2223291B1 (es) * 2003-08-06 2006-03-16 Bioiberica, S.A. Nuevo uso terapeutico de condroitin sulfato.
US7276050B2 (en) * 2004-03-02 2007-10-02 Alan Franklin Trans-scleral drug delivery method and apparatus
US8034796B2 (en) * 2004-04-07 2011-10-11 The University Of Georgia Research Foundation, Inc. Glucosamine and glucosamine/anti-inflammatory mutual prodrugs, compositions, and methods
CN1953660A (zh) 2004-04-07 2007-04-25 佐治亚州大学研究基金会 葡糖胺和葡糖胺/抗炎互联体前药、组合物和方法
RU2260432C1 (ru) * 2004-10-12 2005-09-20 Открытое Акционерное Общество "Нижегородский Химико-Фармацевтический Завод" (Оао "Нижфарм") Средство для лечения болезней суставов
US7335384B2 (en) 2006-03-17 2008-02-26 4K Nutripharma International Nutrient compositions for the treatment and prevention of inflammation and disorders associated therewith
EP2182810B1 (en) * 2007-08-03 2017-11-08 Nucitec S.A. de C.V. Compositions and methods for treatment and prevention of osteoarthritis
KR20100099260A (ko) * 2007-12-12 2010-09-10 디에스엠 아이피 어셋츠 비.브이. 염증성 장애의 치료, 병용-치료 또는 예방을 위한 하이드록시티로솔 및 콘드로이틴을 포함하는 조성물
ES2405314T3 (es) * 2008-05-13 2013-05-30 Apharm S.R.L. Composiciones y uso oral de glicosaminoglicanos
FR2969618B1 (fr) * 2010-12-28 2014-05-16 Pf Medicament Procede de preparation de chondroitine sulfate de sodium
JP6096550B2 (ja) * 2012-04-25 2017-03-15 ロート製薬株式会社 内服組成物
ES2468665B1 (es) * 2012-12-14 2015-06-11 Farmalider, S.A. Composición farmacéutica de sulfato de condroitina y celecoxib
WO2015057520A1 (en) * 2013-10-16 2015-04-23 Novozymes A/S Processes of producing fermentation products
WO2015168671A1 (en) * 2014-05-02 2015-11-05 Arthrodynamic Technologies, Animal Health Division, Inc. Glycosaminoglycan composition and method of use for kidney stone removal
CN104644665A (zh) * 2014-06-26 2015-05-27 黄心诚 治疗关节炎的药物
WO2017029710A1 (ja) * 2015-08-18 2017-02-23 合同会社Pharma Seeds Create NSAIDsまたはヘパリン類含有口腔用組成物
CN112870154B (zh) * 2021-02-03 2022-10-18 四川农业大学 兽用复方塞来昔布纳米脂质体凝胶及其制备方法

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4473551A (en) * 1982-08-23 1984-09-25 Faxon Pharmaceuticals, Inc. Anti-inflammatory composition
US4590067A (en) * 1984-10-18 1986-05-20 Peritain, Ltd. Treatment for periodontal disease
US4647453A (en) * 1984-10-18 1987-03-03 Peritain, Ltd. Treatment for tissue degenerative inflammatory disease
US4772591A (en) * 1985-09-25 1988-09-20 Peritain, Ltd. Method for accelerated wound healing
US6166031A (en) * 1987-10-19 2000-12-26 Pfizer Inc, Substituted tetralins, chromans and related compounds in the treatment of asthma
US5476944A (en) * 1991-11-18 1995-12-19 G. D. Searle & Co. Derivatives of cyclic phenolic thioethers
US6048850A (en) * 1992-09-22 2000-04-11 Young; Donald A. Method of inhibiting prostaglandin synthesis in a human host
US5364845C1 (en) * 1993-03-31 2002-09-10 Nutramax Lab Inc Glusosamine chondroitin and manganese composition for the protection and repair of connective tissue
US5466823A (en) * 1993-11-30 1995-11-14 G.D. Searle & Co. Substituted pyrazolyl benzenesulfonamides
RO118291B1 (ro) * 1993-11-30 2003-04-30 Searle & Co Derivati de pirazol 1,3,4,5 - tetrasubstituiti si compozitie farmaceutica care ii contine
US5434178A (en) * 1993-11-30 1995-07-18 G.D. Searle & Co. 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation
JP3818676B2 (ja) * 1994-07-22 2006-09-06 生化学工業株式会社 ヘパラン硫酸6−o−硫酸基転移酵素
ATE223390T1 (de) * 1995-02-13 2002-09-15 Searle & Co Substituierte isoxazole zur behandlung von entzündung
US5643933A (en) * 1995-06-02 1997-07-01 G. D. Searle & Co. Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors
US5700816A (en) * 1995-06-12 1997-12-23 Isakson; Peter C. Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitor and a leukotriene A4 hydrolase inhibitor
AU6111796A (en) * 1995-06-12 1997-01-09 G.D. Searle & Co. Compositions comprising a cyclooxygenase-2 inhibitor and a 5 -lipoxygenase inhibitor
US5840715A (en) * 1995-12-11 1998-11-24 Inholtra Investment Holdings & Trading, N.V. Dietary regimen of nutritional supplements for relief of symptoms of arthritis
US5916565A (en) * 1996-03-08 1999-06-29 In Clover, Inc. Product and method for treating joint disorders in vertebrates
PT892791E (pt) * 1996-04-12 2003-06-30 Searle & Co N-¬¬4-(5-metil-3-fenilisoxazol-4-il|fenil|sulfonil-propilamida e seu sal de sodio como pro-farmacos de inibidores de cox-2
US6191164B1 (en) * 1996-05-15 2001-02-20 Hoechst Aktiengesellschaft Sulfonamide-substituted chromans, processes for their preparation, their use as a medicament or diagnostic, and medicament comprising them
JP3454832B2 (ja) * 1996-06-07 2003-10-06 バンダービルト ユニバーシティ 抗炎症剤として有用なジヒドロベンゾピランおよび関連化合物
US5843919A (en) * 1996-11-25 1998-12-01 Burger; John A. Composition and method for the treatment of arthritis
US5804594A (en) * 1997-01-22 1998-09-08 Murad; Howard Pharmaceutical compositions and methods for improving wrinkles and other skin conditions
DE19706490C1 (de) * 1997-02-19 1998-09-17 Deutsches Krebsforsch Verfahren zur Herstellung von Säureamiden und zur Metallierung von Verbindungen und Verwendung der nach den Verfahren hergestellten Verbindungen
US6077850A (en) * 1997-04-21 2000-06-20 G.D. Searle & Co. Substituted benzopyran analogs for the treatment of inflammation
US5888514A (en) * 1997-05-23 1999-03-30 Weisman; Bernard Natural composition for treating bone or joint inflammation
US5929050A (en) * 1998-02-27 1999-07-27 Petito; George D. Chondroitin sulfate composition and method for wound treatment
US5922692A (en) * 1998-03-11 1999-07-13 Marino; Richard P. Concentration of glycosaminoglycans and precursors thereto in food products
US6231889B1 (en) * 1998-09-21 2001-05-15 Chronorx, Llc Unit dosage forms for the treatment of herpes simplex
US6136795A (en) * 1998-11-18 2000-10-24 Omni Nutraceuticals, Inc Dietary regimen of nutritional supplements for relief of symptoms of arthritis
DE19859251A1 (de) * 1998-12-22 2000-06-29 Basf Ag Verfahren zur Herstellung von substituierten Chromanderivaten
US6162787A (en) * 1999-04-02 2000-12-19 Immudyne, Inc. Methods for treating arthritis using collagen type II, glucosamine chondroitin sulfate, and compositions
WO2001041783A1 (en) * 1999-12-09 2001-06-14 Bruce Levin Methods and compositions for treatment of inflammatory disease
US20020086070A1 (en) * 2000-03-11 2002-07-04 Kuhrts Eric Hauser Anti-inflammatory and connective tissue repair formulations

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JP2005501850A (ja) 2005-01-20
PL368971A1 (en) 2005-04-04
CN1575182A (zh) 2005-02-02
AU2002336344A2 (en) 2003-03-03
MXPA04001397A (es) 2004-05-27
KR20040047790A (ko) 2004-06-05
IL160087A0 (en) 2004-06-20
EP1416941A1 (en) 2004-05-12
US20030114416A1 (en) 2003-06-19
CA2457452A1 (en) 2003-02-27

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