FR2969618B1 - Procede de preparation de chondroitine sulfate de sodium - Google Patents

Procede de preparation de chondroitine sulfate de sodium

Info

Publication number
FR2969618B1
FR2969618B1 FR1061324A FR1061324A FR2969618B1 FR 2969618 B1 FR2969618 B1 FR 2969618B1 FR 1061324 A FR1061324 A FR 1061324A FR 1061324 A FR1061324 A FR 1061324A FR 2969618 B1 FR2969618 B1 FR 2969618B1
Authority
FR
France
Prior art keywords
sodfate
chondroid
sodium
preparation
sodium chondroid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1061324A
Other languages
English (en)
Other versions
FR2969618A1 (fr
Inventor
Nadine Chomarat
Paul Grech
Guillermo Cueto
Edouardo Rodriguez
Jean Francois Boe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Priority to FR1061324A priority Critical patent/FR2969618B1/fr
Priority to TW100148873A priority patent/TW201306846A/zh
Priority to US13/823,485 priority patent/US20130172289A1/en
Priority to PCT/EP2011/074180 priority patent/WO2012089777A1/fr
Priority to EP11810846.3A priority patent/EP2658876B1/fr
Priority to ARP110104975A priority patent/AR084625A1/es
Publication of FR2969618A1 publication Critical patent/FR2969618A1/fr
Application granted granted Critical
Publication of FR2969618B1 publication Critical patent/FR2969618B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0003—General processes for their isolation or fractionation, e.g. purification or extraction from biomass
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Materials Engineering (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Sustainable Development (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR1061324A 2010-12-28 2010-12-28 Procede de preparation de chondroitine sulfate de sodium Active FR2969618B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR1061324A FR2969618B1 (fr) 2010-12-28 2010-12-28 Procede de preparation de chondroitine sulfate de sodium
TW100148873A TW201306846A (zh) 2010-12-28 2011-12-27 製備軟骨素硫酸鈉的方法
US13/823,485 US20130172289A1 (en) 2010-12-28 2011-12-28 Method for the preparation of sodium chondroitin sulphate
PCT/EP2011/074180 WO2012089777A1 (fr) 2010-12-28 2011-12-28 Procédé de synthèse de sulfate de chondroïtine sodium
EP11810846.3A EP2658876B1 (fr) 2010-12-28 2011-12-28 Procédé de préparation de chondroïtine sulfate de sodium
ARP110104975A AR084625A1 (es) 2010-12-28 2011-12-28 Metodo para la preparacion de sulfato de condroitina sodico

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1061324A FR2969618B1 (fr) 2010-12-28 2010-12-28 Procede de preparation de chondroitine sulfate de sodium

Publications (2)

Publication Number Publication Date
FR2969618A1 FR2969618A1 (fr) 2012-06-29
FR2969618B1 true FR2969618B1 (fr) 2014-05-16

Family

ID=45507676

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1061324A Active FR2969618B1 (fr) 2010-12-28 2010-12-28 Procede de preparation de chondroitine sulfate de sodium

Country Status (6)

Country Link
US (1) US20130172289A1 (fr)
EP (1) EP2658876B1 (fr)
AR (1) AR084625A1 (fr)
FR (1) FR2969618B1 (fr)
TW (1) TW201306846A (fr)
WO (1) WO2012089777A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103665186A (zh) * 2013-10-21 2014-03-26 青岛九龙生物医药有限公司 一种提高硫酸软骨素钠含量的方法
CN104387502B (zh) * 2014-12-08 2015-08-12 张木良 硫酸软骨素制备工艺及其设备
CN104292363B (zh) * 2014-09-30 2016-08-17 江苏奇力康皮肤药业有限公司 一种用于眼药水的鲨鱼软骨素的提取方法
CN109459523B (zh) 2017-09-06 2022-11-08 上海绿谷制药有限公司 一种测定酸性糖可溶性盐重均分子量和含量的方法
CN111662394B (zh) * 2019-03-05 2022-11-04 中国医学科学院药物研究所 硫酸软骨素多糖半合成制备方法和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3118588C2 (de) * 1981-05-11 1983-07-07 Luitpold-Werk, Chemisch-Pharmazeutische Fabrik, 8000 München Verfahren zur Herstellung eines injizierbaren hochreinen Chondroitinpolysulfates, hiernach erhältliches Produkt und pharmazeutische Zusammensetzung
FR2756828B1 (fr) * 1996-12-09 1999-03-05 Fabre Pierre Sante Procede d'obtention d'acide chondroitine sulfate a partir d'organes cartilagineux d'origine aviaire
US7223571B2 (en) * 1998-04-02 2007-05-29 The Board Of Regents Of The Universtiy Of Oklahoma Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same
US20030032620A1 (en) * 2001-07-25 2003-02-13 Annie Landrein Low molecular weight chondroitin sulphate compound having cosmetic activity
US20030114416A1 (en) * 2001-08-14 2003-06-19 Pharmacia Corporation Method and compositions for the treatment and prevention of pain and inflammation with a cyclooxygenase-2 selective inhibitor and chondroitin sulfate
US20040146993A1 (en) * 2002-11-13 2004-07-29 Khare Anil B. Isolating chondroitin sulfate
FR2847256B1 (fr) * 2002-11-15 2005-04-08 Biochimie Appliquee Soc Nouveau procede d'obtention d'acide chondroitine sulfurique et ses utilisations
GB0714500D0 (en) * 2007-07-25 2007-09-05 Hunter Fleming Ltd composition and treatment

Also Published As

Publication number Publication date
AR084625A1 (es) 2013-05-29
US20130172289A1 (en) 2013-07-04
EP2658876B1 (fr) 2014-11-05
FR2969618A1 (fr) 2012-06-29
TW201306846A (zh) 2013-02-16
EP2658876A1 (fr) 2013-11-06
WO2012089777A1 (fr) 2012-07-05

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