CN1511039A - 降低血浆葡萄糖的方法 - Google Patents

降低血浆葡萄糖的方法 Download PDF

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Publication number
CN1511039A
CN1511039A CNA028099958A CN02809995A CN1511039A CN 1511039 A CN1511039 A CN 1511039A CN A028099958 A CNA028099958 A CN A028099958A CN 02809995 A CN02809995 A CN 02809995A CN 1511039 A CN1511039 A CN 1511039A
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CN
China
Prior art keywords
solid
water
poly
filtered
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA028099958A
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English (en)
Chinese (zh)
Inventor
ʷ���ġ�K������
史蒂文·K·勃克
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Genzyme Corp
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of CN1511039A publication Critical patent/CN1511039A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • A61K31/787Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CNA028099958A 2001-04-18 2002-04-10 降低血浆葡萄糖的方法 Pending CN1511039A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US28444501P 2001-04-18 2001-04-18
US60/284,445 2001-04-18
US30556401P 2001-07-13 2001-07-13
US60/305,564 2001-07-13

Publications (1)

Publication Number Publication Date
CN1511039A true CN1511039A (zh) 2004-07-07

Family

ID=26962623

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA028099958A Pending CN1511039A (zh) 2001-04-18 2002-04-10 降低血浆葡萄糖的方法

Country Status (17)

Country Link
US (2) US7229613B2 (cg-RX-API-DMAC7.html)
EP (1) EP1392331B1 (cg-RX-API-DMAC7.html)
JP (2) JP4499363B2 (cg-RX-API-DMAC7.html)
KR (1) KR20040018358A (cg-RX-API-DMAC7.html)
CN (1) CN1511039A (cg-RX-API-DMAC7.html)
AT (1) ATE390927T1 (cg-RX-API-DMAC7.html)
AU (1) AU2002257145B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0209134B8 (cg-RX-API-DMAC7.html)
CA (1) CA2444046C (cg-RX-API-DMAC7.html)
CY (1) CY1119486T1 (cg-RX-API-DMAC7.html)
DE (1) DE60225908T2 (cg-RX-API-DMAC7.html)
DK (2) DK1923064T3 (cg-RX-API-DMAC7.html)
ES (2) ES2637020T3 (cg-RX-API-DMAC7.html)
MX (1) MXPA03009568A (cg-RX-API-DMAC7.html)
NZ (1) NZ528831A (cg-RX-API-DMAC7.html)
PT (1) PT1923064T (cg-RX-API-DMAC7.html)
WO (1) WO2002085377A1 (cg-RX-API-DMAC7.html)

Cited By (4)

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CN105188718A (zh) * 2013-03-15 2015-12-23 建新公司 晚期糖化终产物(age)前体的螯合剂
CN107250189A (zh) * 2014-12-18 2017-10-13 建新公司 用于治疗2型糖尿病的交联聚二烯丙胺共聚物
WO2023023939A1 (en) * 2021-08-24 2023-03-02 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Polymers, compositions and methods for treating hyperuricemia
WO2023023938A1 (en) * 2021-08-24 2023-03-02 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Polymers, compositions and methods for treating hyperuricemia

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US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
AU2002257145B2 (en) * 2001-04-18 2005-06-02 Genzyme Corporation Method for lowering serum glucose
WO2004037274A1 (en) * 2002-10-22 2004-05-06 Genzyme Corporation Amine polymers for promoting bone formation
US7385012B2 (en) 2003-11-03 2008-06-10 Ilypsa, Inc. Polyamine polymers
US7335795B2 (en) 2004-03-22 2008-02-26 Ilypsa, Inc. Crosslinked amine polymers
US7449605B2 (en) * 2003-11-03 2008-11-11 Ilypsa, Inc. Crosslinked amine polymers
US7767768B2 (en) * 2003-11-03 2010-08-03 Ilypsa, Inc. Crosslinked amine polymers
US7608674B2 (en) 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
US7459502B2 (en) * 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
CN1953756A (zh) * 2004-03-26 2007-04-25 三菱制药株式会社 胰岛素抗性改善剂
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
WO2006072054A1 (en) * 2004-12-30 2006-07-06 Genzyme Corporation Zinc-containing treatments for hyperphosphatemia
JP2009507019A (ja) * 2005-09-02 2009-02-19 ジェンザイム・コーポレーション リン酸塩を除去する方法およびそれに使用される重合体
DK1924246T3 (en) 2005-09-15 2016-01-18 Genzyme Corp PORTION LETTER DEFINITION OF amine polymers
BRPI0618352A2 (pt) * 2005-11-08 2011-08-23 Genzyme Corp composições farmacêuticas e métodos de tratamento da hiperfosfatemia em um paciente
US20100135950A1 (en) * 2006-07-05 2010-06-03 Genzyme Corporation Iron(II)-Containing Treatments for Hyperphosphatemia
RU2009111853A (ru) * 2006-09-01 2010-10-10 Юсв Лимитед (In) Способ получения гидрохлорида севеламера и его лекарственной формы
US7964182B2 (en) * 2006-09-01 2011-06-21 USV, Ltd Pharmaceutical compositions comprising phosphate-binding polymer
BRPI0717545A2 (pt) 2006-09-29 2013-10-22 Gezyme Corp Composição farmacêutica, método para tratar uma doença, polímero de amida, rede de polímero, e, método para preparar um polímero de amida
BRPI0720234A2 (pt) 2006-12-14 2013-12-24 Genzyme Corp Composição farmacêutica
US8710154B2 (en) * 2008-09-15 2014-04-29 Shasun Pharmaceuticals Limited Non-aqueous solution process for the preparation of cross-linked polymers
RU2011134847A (ru) * 2009-01-22 2013-02-27 Юсв Лимитед Фармацевтические композиции, содержащие фосфатсвязывающий полимер
US9566299B2 (en) 2013-02-08 2017-02-14 Wockhardt Limited Oral pharmaceutical composition of aliphatic amine polymer or salts thereof
CN106573066A (zh) 2014-06-13 2017-04-19 联合治疗学有限公司 曲前列环素制剂
BR112019013364A2 (pt) 2016-12-28 2020-04-14 Fujifilm Corp emulsão de polímero contendo átomo de nitrogênio ou sal do mesmo, método de produção para o mesmo e método de produção para partículas
EP3698799B1 (en) 2017-10-16 2022-01-26 FUJIFILM Corporation Hyperphosphatemia treatment agent

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JPS6090243A (ja) 1983-10-25 1985-05-21 Nitto Boseki Co Ltd 小球状モノアリルアミン橋かけ重合体の製造方法
US4528347A (en) 1983-11-10 1985-07-09 501 Nitto Boseki, Co. Ltd Process for producing polymers of monoallylamine
US5468727A (en) * 1990-12-13 1995-11-21 Board Of Regents, The University Of Texas System Methods of normalizing metabolic parameters in diabetics
JP3507523B2 (ja) 1993-05-12 2004-03-15 積水化学工業株式会社 糖質吸収抑制剤
US5487888A (en) 1993-05-20 1996-01-30 Geltex, Inc. Iron-binding polymers for oral administration
US5607669A (en) 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
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US6083497A (en) 1997-11-05 2000-07-04 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
US5985938A (en) 1997-11-05 1999-11-16 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
AU2682499A (en) 1998-02-17 1999-08-30 Dimitri R. Kioussis Anion binding polymers and the use thereof
EP1340510A1 (en) * 1998-12-23 2003-09-03 G.D. Searle LLC. Combinations of cholesteryl ester transfer protein inhibitors and bile acid sequestering agents for cardiovascular indications
WO2001025291A1 (en) * 1999-10-07 2001-04-12 University Of Maryland Sugar binding polymers and the use thereof
TWI241195B (en) * 2000-04-10 2005-10-11 Shionogi & Co Preventive agent for bile acidic diarrhea
AU2002257145B2 (en) * 2001-04-18 2005-06-02 Genzyme Corporation Method for lowering serum glucose
US20020198202A1 (en) 2001-06-07 2002-12-26 Wyeth Combination of a PTPase inhibitor and an antilipemic agent

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105188718A (zh) * 2013-03-15 2015-12-23 建新公司 晚期糖化终产物(age)前体的螯合剂
CN107250189A (zh) * 2014-12-18 2017-10-13 建新公司 用于治疗2型糖尿病的交联聚二烯丙胺共聚物
WO2023023939A1 (en) * 2021-08-24 2023-03-02 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Polymers, compositions and methods for treating hyperuricemia
WO2023023938A1 (en) * 2021-08-24 2023-03-02 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Polymers, compositions and methods for treating hyperuricemia
US12478638B2 (en) 2021-08-24 2025-11-25 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Polymers, compositions and methods for treating hyperuricemia

Also Published As

Publication number Publication date
DE60225908T2 (de) 2009-05-14
US20020187121A1 (en) 2002-12-12
JP2010090172A (ja) 2010-04-22
NZ528831A (en) 2005-07-29
BRPI0209134B8 (pt) 2021-05-25
CA2444046A1 (en) 2002-10-31
JP4499363B2 (ja) 2010-07-07
ES2637020T3 (es) 2017-10-10
MXPA03009568A (es) 2004-02-12
JP2004535384A (ja) 2004-11-25
BRPI0209134B1 (pt) 2019-08-27
EP1392331B1 (en) 2008-04-02
EP1392331A1 (en) 2004-03-03
US20070286841A1 (en) 2007-12-13
CA2444046C (en) 2011-06-07
ES2304437T3 (es) 2008-10-16
DE60225908D1 (de) 2008-05-15
WO2002085377A1 (en) 2002-10-31
PT1923064T (pt) 2017-08-23
ATE390927T1 (de) 2008-04-15
WO2002085377A8 (en) 2002-11-28
CY1119486T1 (el) 2018-03-07
US7229613B2 (en) 2007-06-12
KR20040018358A (ko) 2004-03-03
AU2002257145B2 (en) 2005-06-02
DK1923064T3 (en) 2017-10-02
DK1392331T3 (da) 2008-06-23
BR0209134A (pt) 2004-06-15

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C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication