BRPI0209134B8 - uso de um sevelamer ou um sal do mesmo e uso de um colesevelam ou um sal do mesmo - Google Patents

uso de um sevelamer ou um sal do mesmo e uso de um colesevelam ou um sal do mesmo

Info

Publication number
BRPI0209134B8
BRPI0209134B8 BRPI0209134A BRPI0209134B8 BR PI0209134 B8 BRPI0209134 B8 BR PI0209134B8 BR PI0209134 A BRPI0209134 A BR PI0209134A BR PI0209134 B8 BRPI0209134 B8 BR PI0209134B8
Authority
BR
Brazil
Prior art keywords
salt
polymer
colesevelam
amine
patient
Prior art date
Application number
Other languages
English (en)
Portuguese (pt)
Inventor
K Burke Steven
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of BR0209134A publication Critical patent/BR0209134A/pt
Publication of BRPI0209134B1 publication Critical patent/BRPI0209134B1/pt
Publication of BRPI0209134B8 publication Critical patent/BRPI0209134B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BR0209134-8 2001-04-18 2002-04-10 uso de um sevelamer ou um sal do mesmo e uso de um colesevelam ou um sal do mesmo BRPI0209134B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28444501P 2001-04-18 2001-04-18
US30556401P 2001-07-13 2001-07-13
PCT/US2002/011493 WO2002085377A1 (en) 2001-04-18 2002-04-10 Method for lowering serum glucose

Publications (3)

Publication Number Publication Date
BR0209134A BR0209134A (pt) 2004-06-15
BRPI0209134B1 BRPI0209134B1 (pt) 2019-08-27
BRPI0209134B8 true BRPI0209134B8 (pt) 2021-05-25

Family

ID=26962623

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0209134-8 BRPI0209134B8 (pt) 2001-04-18 2002-04-10 uso de um sevelamer ou um sal do mesmo e uso de um colesevelam ou um sal do mesmo

Country Status (17)

Country Link
US (2) US7229613B2 (cg-RX-API-DMAC7.html)
EP (1) EP1392331B1 (cg-RX-API-DMAC7.html)
JP (2) JP4499363B2 (cg-RX-API-DMAC7.html)
KR (1) KR20040018358A (cg-RX-API-DMAC7.html)
CN (1) CN1511039A (cg-RX-API-DMAC7.html)
AT (1) ATE390927T1 (cg-RX-API-DMAC7.html)
AU (1) AU2002257145B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0209134B8 (cg-RX-API-DMAC7.html)
CA (1) CA2444046C (cg-RX-API-DMAC7.html)
CY (1) CY1119486T1 (cg-RX-API-DMAC7.html)
DE (1) DE60225908T2 (cg-RX-API-DMAC7.html)
DK (2) DK1392331T3 (cg-RX-API-DMAC7.html)
ES (2) ES2304437T3 (cg-RX-API-DMAC7.html)
MX (1) MXPA03009568A (cg-RX-API-DMAC7.html)
NZ (1) NZ528831A (cg-RX-API-DMAC7.html)
PT (1) PT1923064T (cg-RX-API-DMAC7.html)
WO (1) WO2002085377A1 (cg-RX-API-DMAC7.html)

Families Citing this family (30)

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US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
DK1392331T3 (da) * 2001-04-18 2008-06-23 Genzyme Corp Anvendelse af colesevelam eller sevelamer, hydrogenchlorid til sænkning af serumglucoseniveauet
AU2003282867A1 (en) * 2002-10-22 2004-05-13 Genzyme Corporation Amine polymers for promoting bone formation
US7385012B2 (en) 2003-11-03 2008-06-10 Ilypsa, Inc. Polyamine polymers
US7767768B2 (en) * 2003-11-03 2010-08-03 Ilypsa, Inc. Crosslinked amine polymers
US7449605B2 (en) * 2003-11-03 2008-11-11 Ilypsa, Inc. Crosslinked amine polymers
US7608674B2 (en) * 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
US7335795B2 (en) * 2004-03-22 2008-02-26 Ilypsa, Inc. Crosslinked amine polymers
US7459502B2 (en) * 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
CN1953756A (zh) * 2004-03-26 2007-04-25 三菱制药株式会社 胰岛素抗性改善剂
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
WO2006072054A1 (en) * 2004-12-30 2006-07-06 Genzyme Corporation Zinc-containing treatments for hyperphosphatemia
EP1951266A2 (en) * 2005-09-02 2008-08-06 Genzyme Corporation Method for removing phosphate and polymer used therefore
DK1924246T3 (en) 2005-09-15 2016-01-18 Genzyme Corp PORTION LETTER DEFINITION OF amine polymers
EP1945196A2 (en) * 2005-11-08 2008-07-23 Genzyme Corporation Magnesium-containing polymers for hyperphosphatemia
US20100135950A1 (en) * 2006-07-05 2010-06-03 Genzyme Corporation Iron(II)-Containing Treatments for Hyperphosphatemia
CA2749074A1 (en) * 2006-09-01 2008-05-29 Usv Limited Process for the preparation of sevelamer hydrochloride and formulation thereof
US7964182B2 (en) * 2006-09-01 2011-06-21 USV, Ltd Pharmaceutical compositions comprising phosphate-binding polymer
EP2066293A2 (en) 2006-09-29 2009-06-10 Genzyme Corporation Amide dendrimer compositions
JP2010513271A (ja) 2006-12-14 2010-04-30 ゲンズイメ コーポレーション アミド−アミンポリマー組成物
US8710154B2 (en) * 2008-09-15 2014-04-29 Shasun Pharmaceuticals Limited Non-aqueous solution process for the preparation of cross-linked polymers
BRPI1006969A2 (pt) * 2009-01-22 2016-04-12 Usv Ltd composições farmacêuticas compreendendo polímero de ligação a fosfato
WO2014122586A1 (en) 2013-02-08 2014-08-14 Wockhardt Limited Oral pharmaceutical composition of aliphatic amine polymer or salts thereof
SG11201506413PA (en) * 2013-03-15 2015-09-29 Genzyme Corp Sequestrants of advanced glycation end product (age) precursors
US20170095432A1 (en) 2014-06-13 2017-04-06 United Therapeutics Corporation Treprostinil formulations
MA41202A (fr) * 2014-12-18 2017-10-24 Genzyme Corp Copolymères polydiallymine réticulé pour le traitement du diabète de type 2
TWI757398B (zh) 2016-12-28 2022-03-11 日商富士軟片股份有限公司 含氮原子的聚合物或其鹽的乳化液、其製造方法、及粒子的製造方法
CN111225674A (zh) 2017-10-16 2020-06-02 富士胶片株式会社 高磷血症治疗剂
ES2995007T3 (en) 2021-08-24 2025-02-05 Waterstone Pharmaceuticals Wuhan Co Ltd Polymers, compositions and methods for treating hyperuricemia
WO2023023939A1 (en) * 2021-08-24 2023-03-02 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Polymers, compositions and methods for treating hyperuricemia

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US4528847A (en) * 1983-10-04 1985-07-16 D. Halmi And Associates, Inc. Flow metering device with recessed pressure taps
JPS6090243A (ja) 1983-10-25 1985-05-21 Nitto Boseki Co Ltd 小球状モノアリルアミン橋かけ重合体の製造方法
CA1220896A (en) 1983-11-10 1987-04-21 Susumu Harada Process for producing polymers of monoallylamine
US5468727A (en) * 1990-12-13 1995-11-21 Board Of Regents, The University Of Texas System Methods of normalizing metabolic parameters in diabetics
JP3507523B2 (ja) 1993-05-12 2004-03-15 積水化学工業株式会社 糖質吸収抑制剤
US5487888A (en) 1993-05-20 1996-01-30 Geltex, Inc. Iron-binding polymers for oral administration
US5900475A (en) 1994-06-10 1999-05-04 Geltex Pharmaceuticals, Inc. Hydrophobic sequestrant for cholesterol depletion
US5618530A (en) 1994-06-10 1997-04-08 Geltex Pharmaceuticals, Inc. Hydrophobic amine polymer sequestrant and method of cholesterol depletion
US5703188A (en) 1993-06-02 1997-12-30 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5607669A (en) 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
US5624963A (en) 1993-06-02 1997-04-29 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5496545A (en) 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5667775A (en) 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
TW474813B (en) 1994-06-10 2002-02-01 Geltex Pharma Inc Alkylated composition for removing bile salts from a patient
JP4156684B2 (ja) * 1996-03-05 2008-09-24 三菱化学株式会社 高リン血症予防および／または治療剤
US6203785B1 (en) 1996-12-30 2001-03-20 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
US5925379A (en) 1997-03-27 1999-07-20 Geltex Pharmaceuticals, Inc. Interpenetrating polymer networks for sequestration of bile acids
TW592727B (en) 1997-04-04 2004-06-21 Chugai Pharmaceutical Co Ltd Phosphate-binding polymer preparations
US6423754B1 (en) 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
FR2766195A1 (fr) 1997-07-21 1999-01-22 Transgene Sa Polymeres cationiques, complexes associant lesdits polymeres cationiques et des substances therapeutiquement actives comprenant au moins une charges negative, notamment des acides nucleiques, et leur utilisation en therapie genique
US5985938A (en) 1997-11-05 1999-11-16 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
US6083497A (en) 1997-11-05 2000-07-04 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
AU2682499A (en) 1998-02-17 1999-08-30 Dimitri R. Kioussis Anion binding polymers and the use thereof
DE69908644T2 (de) * 1998-12-23 2004-05-13 G.D. Searle Llc, Chicago Kombnationen von cholesteryl ester transfer protein inhibitoren und gallensäure sequestriermitteln für kardiovaskuläre indikationen
AU7856200A (en) * 1999-10-07 2001-05-10 University Of Maryland Sugar binding polymers and the use thereof
TWI241195B (en) * 2000-04-10 2005-10-11 Shionogi & Co Preventive agent for bile acidic diarrhea
DK1392331T3 (da) * 2001-04-18 2008-06-23 Genzyme Corp Anvendelse af colesevelam eller sevelamer, hydrogenchlorid til sænkning af serumglucoseniveauet
WO2002100397A1 (en) * 2001-06-07 2002-12-19 Wyeth COMBINATION OF A PTPase INHIBITOR AND AN ANTILIPEMIC AGENT

Also Published As

Publication number Publication date
JP4499363B2 (ja) 2010-07-07
JP2004535384A (ja) 2004-11-25
BRPI0209134B1 (pt) 2019-08-27
EP1392331B1 (en) 2008-04-02
CA2444046A1 (en) 2002-10-31
US20020187121A1 (en) 2002-12-12
DE60225908D1 (de) 2008-05-15
ES2304437T3 (es) 2008-10-16
DK1392331T3 (da) 2008-06-23
CN1511039A (zh) 2004-07-07
CY1119486T1 (el) 2018-03-07
BR0209134A (pt) 2004-06-15
ES2637020T3 (es) 2017-10-10
WO2002085377A8 (en) 2002-11-28
DK1923064T3 (en) 2017-10-02
JP2010090172A (ja) 2010-04-22
KR20040018358A (ko) 2004-03-03
MXPA03009568A (es) 2004-02-12
AU2002257145B2 (en) 2005-06-02
US7229613B2 (en) 2007-06-12
US20070286841A1 (en) 2007-12-13
NZ528831A (en) 2005-07-29
DE60225908T2 (de) 2009-05-14
PT1923064T (pt) 2017-08-23
EP1392331A1 (en) 2004-03-03
WO2002085377A1 (en) 2002-10-31
CA2444046C (en) 2011-06-07
ATE390927T1 (de) 2008-04-15

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Legal Events

Date Code Title Description
B25G Requested change of headquarter approved

Owner name: GENZYME CORPORATION (US)

Free format text: SEDE ALTERADA CONFORME SOLICITADO NA PETICAO NO 018080029522/SP DE 14/05/2008.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 27/08/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 27/08/2019, OBSERVADAS AS CONDICOES LEGAIS

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 10/04/2002 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

Free format text: PATENTE EXTINTA EM 10/04/2022