CN1438981A - 制备r－1－(芳氧基)丙－2－醇的方法 - Google Patents

制备r－1－(芳氧基)丙－2－醇的方法 Download PDF

Info

Publication number
CN1438981A
CN1438981A CN01808380A CN01808380A CN1438981A CN 1438981 A CN1438981 A CN 1438981A CN 01808380 A CN01808380 A CN 01808380A CN 01808380 A CN01808380 A CN 01808380A CN 1438981 A CN1438981 A CN 1438981A
Authority
CN
China
Prior art keywords
aryloxy
propane
trialkylsiloxy
propan
catalyzer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN01808380A
Other languages
English (en)
Chinese (zh)
Inventor
J·F·拉罗
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shasun Pharma Solutions Inc
Original Assignee
Rhodia Chirex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhodia Chirex Inc filed Critical Rhodia Chirex Inc
Publication of CN1438981A publication Critical patent/CN1438981A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/02—Preparation of ethers from oxiranes
    • C07C41/03—Preparation of ethers from oxiranes by reaction of oxirane rings with hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/26—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B51/00—Introduction of protecting groups or activating groups, not provided for in the preceding groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00—Asymmetric syntheses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/1884—Preparation; Treatments not provided for in C07F7/20 by dismutation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CN01808380A 2000-04-21 2001-04-20 制备r－1－(芳氧基)丙－2－醇的方法 Pending CN1438981A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19894200P 2000-04-21 2000-04-21
US60/198,942 2000-04-21

Publications (1)

Publication Number Publication Date
CN1438981A true CN1438981A (zh) 2003-08-27

Family

ID=22735535

Family Applications (1)

Application Number Title Priority Date Filing Date
CN01808380A Pending CN1438981A (zh) 2000-04-21 2001-04-20 制备r－1－(芳氧基)丙－2－醇的方法

Country Status (7)

Country Link
US (1) US6448449B2 (https=)
EP (1) EP1280753A1 (https=)
JP (1) JP2003531184A (https=)
KR (1) KR20020097223A (https=)
CN (1) CN1438981A (https=)
CA (1) CA2406215A1 (https=)
WO (1) WO2001081286A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112079958A (zh) * 2019-06-12 2020-12-15 中国石化扬子石油化工有限公司 一种碳五共聚石油树脂的制备方法

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE285821T1 (de) * 1999-10-08 2005-01-15 Affinium Pharm Inc Fab i inhibitoren
US20020013519A1 (en) * 2000-06-14 2002-01-31 Scott Adams Secure test and test result delivery system
CA2444597A1 (en) * 2001-04-06 2002-10-06 Affinium Pharmaceuticals, Inc. Fab i inhibitors
EP1575951B1 (en) 2002-12-06 2014-06-25 Debiopharm International SA Heterocyclic compounds, methods of making them and their use in therapy
DE602004016831D1 (de) 2003-03-17 2008-11-13 Affinium Pharm Inc Pharmazeutische zusammensetzungen inhibitoren von fab i und weitere antibiotika enthaltend
EP2848614A3 (en) 2004-06-04 2015-07-29 Debiopharm International SA Acrylamide derivatives as antibiotic agents
EP1973902A2 (en) * 2005-12-05 2008-10-01 Affinium Pharmaceuticals, Inc. 3-heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents
EP2687533B1 (en) 2006-07-20 2017-07-19 Debiopharm International SA Acrylamide derivatives as FAB I inhibitors
WO2008098374A1 (en) 2007-02-16 2008-08-21 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab i inhibitors
KR101503745B1 (ko) * 2010-02-25 2015-03-19 에스케이이노베이션 주식회사 나이트레이트 음이온의 이산화탄소/에폭사이드 공중합 촉매 시스템
SI2861608T1 (sl) 2012-06-19 2019-08-30 Debiopharm International Sa Derivati predzdravila (E)-N-metil-N-((3-metilbenzofuran-2-IL)metil)- 3-(7-okso-5,6,7,8-tetrahidro-1 ,8-nafthiridin-3-il)akrilamid
BR122023021456A2 (pt) 2016-02-26 2024-02-20 Debiopharm International S.A. Uso de di-hidrogeno fosfato de {6- [(e)-3-{metil[(3-metil-1-benfofuran-2- iol)metil]amino)-3- oxopro-1-en-1-il]-2-oxo-3,4-di-hidro-1,8-naftiridin-1(2h)- il}metila para tratamento de osteomielite do pé diabético e composição farmacêutica
LT3923914T (lt) 2019-02-14 2023-07-25 Debiopharm International S.A. Afabicino kompozicija, jos gamybos būdas
CN113939306B (zh) 2019-06-14 2024-07-19 德彪药业国际股份公司 用于治疗涉及生物膜的细菌感染的药物及其用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8525953D0 (en) * 1985-10-21 1985-11-27 Mcneilab Inc Preparation of galactopyranoside
GB8525954D0 (en) * 1985-10-21 1985-11-27 Mcneilab Inc Chlorination of carbohydrates &c alcohols
JP2620290B2 (ja) * 1988-03-11 1997-06-11 旭電化工業株式会社 シリルオキシ基を有するアリールエーテル化合物の製造法
AU4376589A (en) * 1988-11-07 1990-05-10 Gist-Brocades N.V. Optically active benzoxazines and benzothiazines
US5637739A (en) 1990-03-21 1997-06-10 Research Corporation Technologies, Inc. Chiral catalysts and catalytic epoxidation catalyzed thereby
US5559222A (en) * 1995-02-03 1996-09-24 Eli Lilly And Company Preparation of 1-(2'-deoxy-2',2'-difluoro-D-ribo-pentofuranosyl)-cytosine from 2-deoxy-2,2-difluoro-β-D-ribo-pentopyranose
US5665890A (en) * 1995-03-14 1997-09-09 President And Fellows Of Harvard College Stereoselective ring opening reactions
US6207847B1 (en) * 1997-07-10 2001-03-27 E. I. Du Pont De Nemours And Company Manufacture of optically active halohydrin trialkylsilyl ethers
JPH11269131A (ja) 1998-03-20 1999-10-05 Asahi Glass Co Ltd １−アシルオキシ−２−プロパノールの製造方法
JPH11279100A (ja) * 1998-03-25 1999-10-12 Asahi Glass Co Ltd 光学活性な１−置換−２−プロパノールの製造方法
JP2000063314A (ja) * 1998-08-14 2000-02-29 Asahi Glass Co Ltd 光学活性な１−置換−２−プロパノールの製造方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112079958A (zh) * 2019-06-12 2020-12-15 中国石化扬子石油化工有限公司 一种碳五共聚石油树脂的制备方法

Also Published As

Publication number Publication date
KR20020097223A (ko) 2002-12-31
WO2001081286A1 (en) 2001-11-01
US6448449B2 (en) 2002-09-10
US20020007090A1 (en) 2002-01-17
JP2003531184A (ja) 2003-10-21
CA2406215A1 (en) 2001-11-01
EP1280753A1 (en) 2003-02-05

Similar Documents

Publication Publication Date Title
CN1438981A (zh) 制备r－1－(芳氧基)丙－2－醇的方法
US6946566B2 (en) Process for preparation of optically active halogeno hydroxypropyl compound and glycidyl compound
US8329931B2 (en) Organoaluminum compound
JP2009531466A (ja) ＨＭＧ−ＣｏＡ還元酵素阻害剤の中間体の製造方法
KR100953879B1 (ko) 신규의 광학 활성 화합물, 카르복실산 유도체의 속도론적광학 분할 방법 및 이를 위한 촉매
CN1589263A (zh) 光学活性氧代庚烯酸酯的制备方法
JP2010030992A (ja) 光学活性アミン化合物の製造方法
JP3631070B2 (ja) 光学活性含弗素ビナフトール誘導体
EP3106453A1 (en) Method for producing optically active compound, and novel metal-diamine complex
CN1291985A (zh) 三氟甲磺酸的硅烷基化方法
Jankowski et al. The reaction of trimethylsilyl ethylene oxide with α-sulfonyl anions and α, α-sulfonyl dianions. A method for stereocontrolled synthesis of (E)-and (Z)-allylic alcohols
US6586644B2 (en) Process for producing optically active propargyl alcohols
US20010044534A1 (en) Pyrimidine derivative salt
CN1835918A (zh) 外消旋2－{[2－(4－羟基苯基)乙基]硫基}－3－[4－(2－{4－[(甲磺酰基)氧基]苯氧基}乙基)苯基]－丙酸的制备方法
WO2021064205A1 (fr) Procede de preparation d'alcenylaminoboranes et de leurs derives, et leurs utilisations
WO2021002407A1 (ja) フルオロアルキル基含有化合物とその製造方法
JP4407191B2 (ja) 光学活性ハロゲノヒドロキシプロピル化合物およびグリシジル化合物の製造法
CN1300157C (zh) 多齿膦化合物的制备方法
FR2887873A1 (fr) PROCEDE DE PREPARATION D'UN ALCYNE PRESENTANT UN GROUPE HYDROXYLE OPTIQUEMENT ACTIF EN POSITION b OU g D'UNE TRIPLE LIAISON ET PRODUITS INTERMEDIAIRES OBTENUS
CN120230062A (zh) 一种(r)-4-丙基-二氢呋喃-2-酮的制备方法
JP2518102B2 (ja) 光学活性アルコ―ルの製造法並びに光学活性アルコ―ルの分割法
KR20200054896A (ko) 요오드 함유 규소 화합물의 제조 방법
KR100976749B1 (ko) 글리시딜 에테르의 제조 방법
Maryanoff Synthesis and Utilization of Compounds with
JP2000334307A (ja) エノン類の不斉エポキシ化触媒及びそれを用いた光学活性エポキシドの製造方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication