CN1374865A - 用于治疗咳嗽的nociceptin受体ORL-1激动剂 - Google Patents
用于治疗咳嗽的nociceptin受体ORL-1激动剂 Download PDFInfo
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- CN1374865A CN1374865A CN00813077A CN00813077A CN1374865A CN 1374865 A CN1374865 A CN 1374865A CN 00813077 A CN00813077 A CN 00813077A CN 00813077 A CN00813077 A CN 00813077A CN 1374865 A CN1374865 A CN 1374865A
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- alkyl
- aryl
- hydrogen
- low
- cycloalkyl
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- 206010011224 Cough Diseases 0.000 title claims abstract description 26
- 108010020615 nociceptin receptor Proteins 0.000 title claims abstract description 14
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- 125000003118 aryl group Chemical group 0.000 claims abstract description 34
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- 238000011282 treatment Methods 0.000 claims abstract description 23
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims abstract description 22
- 125000000623 heterocyclic group Chemical group 0.000 claims abstract description 16
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- 125000001072 heteroaryl group Chemical group 0.000 claims abstract description 14
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract description 12
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- 125000002619 bicyclic group Chemical group 0.000 claims abstract description 5
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- 125000000547 substituted alkyl group Chemical group 0.000 claims abstract description 4
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- 125000004649 C2-C8 alkynyl group Chemical group 0.000 claims description 2
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- 125000004442 acylamino group Chemical group 0.000 claims description 2
- 125000004183 alkoxy alkyl group Chemical group 0.000 claims description 2
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- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract description 4
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CN104302623A (zh) * | 2012-05-01 | 2015-01-21 | 住友化学株式会社 | 哌啶化合物及其有害生物防除用途 |
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-
1999
- 1999-07-26 US US09/359,771 patent/US6262066B1/en not_active Expired - Lifetime
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2000
- 2000-01-26 AU AU26298/00A patent/AU2629800A/en not_active Abandoned
- 2000-01-26 JP JP2001511934A patent/JP2003505420A/ja active Pending
- 2000-01-26 MX MXPA02001033A patent/MXPA02001033A/es unknown
- 2000-01-26 CA CA002379398A patent/CA2379398A1/en not_active Abandoned
- 2000-01-26 HU HU0203458A patent/HUP0203458A3/hu unknown
- 2000-01-26 BR BR0012801-5A patent/BR0012801A/pt not_active IP Right Cessation
- 2000-01-26 CN CN00813077A patent/CN1374865A/zh active Pending
- 2000-01-26 EP EP00904560A patent/EP1200087A1/en not_active Withdrawn
- 2000-01-26 WO PCT/US2000/001853 patent/WO2001007050A1/en not_active Application Discontinuation
-
2001
- 2001-01-25 US US09/769,824 patent/US6455527B2/en not_active Expired - Lifetime
-
2002
- 2002-01-11 ZA ZA200200275A patent/ZA200200275B/xx unknown
- 2002-01-25 NO NO20020392A patent/NO20020392L/no not_active Application Discontinuation
- 2002-05-08 HK HK02103499.8A patent/HK1042236A1/zh unknown
- 2002-05-23 US US10/155,277 patent/US6716846B2/en not_active Expired - Fee Related
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2004
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104302623A (zh) * | 2012-05-01 | 2015-01-21 | 住友化学株式会社 | 哌啶化合物及其有害生物防除用途 |
Also Published As
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US6262066B1 (en) | 2001-07-17 |
HK1042236A1 (zh) | 2002-08-09 |
EP1200087A1 (en) | 2002-05-02 |
NO20020392D0 (no) | 2002-01-25 |
WO2001007050A1 (en) | 2001-02-01 |
US6455527B2 (en) | 2002-09-24 |
HUP0203458A3 (en) | 2004-01-28 |
HUP0203458A2 (hu) | 2003-02-28 |
US7094784B2 (en) | 2006-08-22 |
ZA200200275B (en) | 2003-06-25 |
US20030073690A1 (en) | 2003-04-17 |
AU2629800A (en) | 2001-02-13 |
US6716846B2 (en) | 2004-04-06 |
US20010011092A1 (en) | 2001-08-02 |
US20040152707A1 (en) | 2004-08-05 |
MXPA02001033A (es) | 2002-08-20 |
JP2003505420A (ja) | 2003-02-12 |
CA2379398A1 (en) | 2001-02-01 |
BR0012801A (pt) | 2002-05-07 |
NO20020392L (no) | 2002-03-25 |
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