IT202200011057A1 - Carriers nanotecnologici degli agonisti del recettore nop - Google Patents

Carriers nanotecnologici degli agonisti del recettore nop

Info

Publication number
IT202200011057A1
IT202200011057A1 IT102022000011057A IT202200011057A IT202200011057A1 IT 202200011057 A1 IT202200011057 A1 IT 202200011057A1 IT 102022000011057 A IT102022000011057 A IT 102022000011057A IT 202200011057 A IT202200011057 A IT 202200011057A IT 202200011057 A1 IT202200011057 A1 IT 202200011057A1
Authority
IT
Italy
Prior art keywords
nanotechnological
carriers
receptor agonists
nop receptor
nop
Prior art date
Application number
IT102022000011057A
Other languages
English (en)
Inventor
Bruno D'agostino
Giuseppe Spaziano
Renata Esposito
Davida Mirra
Rosanna Filosa
Liberato Berrino
Rosario Pignatello
Carmelo Puglia
Original Assignee
Univ Degli Studi Della Campania Luigi Vanvitelli
Univ Degli Studi Di Catania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Degli Studi Della Campania Luigi Vanvitelli, Univ Degli Studi Di Catania filed Critical Univ Degli Studi Della Campania Luigi Vanvitelli
Priority to IT102022000011057A priority Critical patent/IT202200011057A1/it
Publication of IT202200011057A1 publication Critical patent/IT202200011057A1/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/5123Organic compounds, e.g. fats, sugars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5192Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
IT102022000011057A 2022-05-26 2022-05-26 Carriers nanotecnologici degli agonisti del recettore nop IT202200011057A1 (it)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IT102022000011057A IT202200011057A1 (it) 2022-05-26 2022-05-26 Carriers nanotecnologici degli agonisti del recettore nop

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102022000011057A IT202200011057A1 (it) 2022-05-26 2022-05-26 Carriers nanotecnologici degli agonisti del recettore nop

Publications (1)

Publication Number Publication Date
IT202200011057A1 true IT202200011057A1 (it) 2023-11-26

Family

ID=82850273

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102022000011057A IT202200011057A1 (it) 2022-05-26 2022-05-26 Carriers nanotecnologici degli agonisti del recettore nop

Country Status (1)

Country Link
IT (1) IT202200011057A1 (it)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001007050A1 (en) * 1999-07-26 2001-02-01 Schering Corporation Nociceptin receptor orl-1 agonists for use in treating cough
ITNA20090026A1 (it) * 2009-05-14 2010-11-15 Agostino Bruno D Agonisti del recettore nop e loro usi terapeutici

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001007050A1 (en) * 1999-07-26 2001-02-01 Schering Corporation Nociceptin receptor orl-1 agonists for use in treating cough
ITNA20090026A1 (it) * 2009-05-14 2010-11-15 Agostino Bruno D Agonisti del recettore nop e loro usi terapeutici

Non-Patent Citations (49)

* Cited by examiner, † Cited by third party
Title
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D'AGOSTINO BORLOTTI DCALO GON NRUSSIAN MGUERRINI RDE NARDO MMAZZEO FCANDELETTI SROSSI F: "Nociceptin modates bronchoconstriction induced by sensory nerve activation in mouse lung", AM J RESPIR CELL MOL BIOL., 2010
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FRANCESCO MENZELLA, GIULIA GHIDONI, CARLA GALEONE, SILVIA CAPOBELLI, CHIARA SCELFO, NICOLA COSIMO FACCIOLONGO.: "Immune aspects related to viral infections in severe Ashma and the role of Omalizumab", BIOMEDICINES, 2021
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KAWASHIMA Y.NIWA THANDA T.TAKEUCHI H.IWAMOTO T.ITOH Y.: "Preparation of expanded-release spherical micro-matrix of ibuprofen with acrylic polymer by the emulsion-solvent diffusion method for improving bioavailability", CHEM PHARM BULL., 1989
KIGUCHI NDING HKISHIOKA SKO MC: "Nociceptin/Orphanin FQ peptide receptor-related Ligands as novel Analgesics", CURR TOP MEAN CHEM, 2020
KOICHI HIROSERIFUMI IWATATOMOHIRO TAMACHIHIROSHI NAKAJIMA: "Allergies airway inflammation: key players beyond the Th2 celi pathway", IMMUNOL REV., 2017
LADURON PM.: "Axonal transport of opiate transporters in capsaicin-sensitive neurones", BRAIN RES
LAMBERT DG: "The nociceptin/orphanin FQ receptor: A target with broad therapeutic potential", NATURE, 2008
LOW MRISSE PANALINE EDECREASE GGUERRINI RADJUST DADVENIER C: "Nociceptin/orphanin FQ inhibits electrically induced contractions of the human bronchus via NOP receptor activation", PEPTIDES, 2005
MA C, WU M, YE WANG W, WANG W, HUANG Y, PAN X, WU C., DRUG DELIV TRANSL RES, vol. II, no. 3, June 2021 (2021-06-01), pages 1218 - 1235
MARTA PERIZ, FRANCISCO J PEREZ-CANO, MARIA J RODRIGUEZ-LAGUNAS TRINITAT CAMBRAS, SANTIAGO PASTOR-SOPLIN, IVAN BEST, MARGARIDA CAST: "Development and Characterization of an Allergies Ashma Rat Model for Interventional Studies", J MOL SCI, 2020
MCLEOD R L ET AL: "Antitussive profile of the NOP agonist Ro-64-6198 in the guinea pig", PHARMACOLOGY, S. KARGER AG, CH, vol. 71, no. 3, 1 July 2004 (2004-07-01), pages 143 - 149, XP009130512, ISSN: 0031-7012, DOI: 10.1159/000077448 *
MCLEOD RLTULSHIAN DBBOLSER DC ET AL.: "Pharmacological profile of the NOP agonist and cough suppressant agent SCH 486757 (8-[bis(2-chlorophyyl)methyl]-3-(2-pyridinyl)-8-azabicyclo[3.2.1]octan-3-ol) in preclinical models", EUR J PHARMACOL, 2010
MODIL JSPASTERNAK GW.: "The molecular and behavioral pharmacology of the orphanin FQ/Nociceptin peptide and receptor family", PHARMACOL REV., 2001
MOHAMED BRAHIM ERRAHMANI, KARIMA FELLAGUE CHEBRA, ZOHOR MESSAOUDI: "Multidimensional analysis of genetic background and environmental factors: Cases of atopy in asthmatic children", ARCH PEDATR., 2020
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ON NROVIEZZO FMATTEIS MLANARO ACALO GGUERRINI RDE GRUTTOLA LRANGE GCIRINO GROSSI F: "Harmful/orphanin FQ receptor activation decreases the airway hyperresponsiveness induced by allergen in sensitized mice", AM J PHYSIOL LUNG CELI MOL PHYSIOL., 2013
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