CN1371381A - 改进的无定形头孢泊肟酯 - Google Patents

改进的无定形头孢泊肟酯 Download PDF

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Publication number
CN1371381A
CN1371381A CN00812246A CN00812246A CN1371381A CN 1371381 A CN1371381 A CN 1371381A CN 00812246 A CN00812246 A CN 00812246A CN 00812246 A CN00812246 A CN 00812246A CN 1371381 A CN1371381 A CN 1371381A
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CN
China
Prior art keywords
cefpodoxime proxetil
solvent
mixture
amorphous form
acetone
Prior art date
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Pending
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CN00812246A
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English (en)
Chinese (zh)
Inventor
Y·库马
R·K·阿罗拉
K·辛格
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Ranbaxy Laboratories Ltd
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Ranbaxy Laboratories Ltd
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Application filed by Ranbaxy Laboratories Ltd filed Critical Ranbaxy Laboratories Ltd
Publication of CN1371381A publication Critical patent/CN1371381A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN00812246A 1999-07-30 2000-07-24 改进的无定形头孢泊肟酯 Pending CN1371381A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1036DE1999 IN191496B (enExample) 1999-07-30 1999-07-30
IN1036/DEL/99 1999-07-30

Publications (1)

Publication Number Publication Date
CN1371381A true CN1371381A (zh) 2002-09-25

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ID=11092065

Family Applications (1)

Application Number Title Priority Date Filing Date
CN00812246A Pending CN1371381A (zh) 1999-07-30 2000-07-24 改进的无定形头孢泊肟酯

Country Status (9)

Country Link
US (1) US6602999B1 (enExample)
EP (1) EP1204667A4 (enExample)
JP (1) JP2003506329A (enExample)
CN (1) CN1371381A (enExample)
AU (1) AU5839100A (enExample)
BR (1) BR0012865A (enExample)
IN (1) IN191496B (enExample)
WO (1) WO2001009143A1 (enExample)
ZA (1) ZA200200692B (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110248951A (zh) * 2017-02-01 2019-09-17 阿堤亚制药公司 用于治疗丙型肝炎病毒的核苷酸半硫酸盐
CN110251467A (zh) * 2019-06-26 2019-09-20 北京济美堂医药研究有限公司 一种无定形态头孢妥仑匹酯组合物的制备方法
CN110437259A (zh) * 2019-08-14 2019-11-12 中国药科大学 头孢泊肟酯柚皮素共无定形物及其制备方法
CN114409665A (zh) * 2016-06-16 2022-04-29 泽农医药公司 螺-吲哚酮化合物的固态形式

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT408226B (de) * 1999-05-05 2001-09-25 Biochemie Gmbh Kristalliner 7-(2-(2-formylaminothiazol-4-yl)-2
EP1373276A4 (en) 2001-02-27 2005-03-02 Ranbaxy Lab Ltd PROCESS FOR THE PRODUCTION OF CEFPODOXIM PROXETIL
TW200942516A (en) * 2004-10-18 2009-10-16 Teva Pharma Processes for preparing amorphous atorvastatin hemi-calcium
MX2007014363A (es) * 2005-05-16 2009-04-15 Elan Pharma Int Ltd Composiciones de liberacion controlada y en forma de nanoparticulas que comprenden una cefalosporina.
KR100840132B1 (ko) * 2007-04-17 2008-06-23 재단법인서울대학교산학협력재단 포화 액체 이산화탄소를 사용한 세포독심 프록세틸의 건조
CN104768935A (zh) * 2012-09-11 2015-07-08 雷迪博士实验室有限公司 恩杂鲁胺的多晶型形式及其制备
RS62676B1 (sr) 2012-09-11 2021-12-31 Medivation Prostate Therapeutics Llc Formulacije enzalutamida
CA3182565A1 (en) 2015-03-06 2016-09-15 Atea Pharmaceuticals, Inc. .beta.-d-2'-deoxy-2'-.alpha.-fluoro-2'-.beta.-c-substituted-2-modified-n6-substituted purine nucleotides for hcv treatment
WO2017046756A1 (en) * 2015-09-18 2017-03-23 Lupin Limited Proxetil and axetil esters of cefixime
CN108884111A (zh) * 2016-05-09 2018-11-23 苏州科睿思制药有限公司 克立硼罗游离形式的晶型及其制备方法和用途
US11447506B2 (en) 2016-05-09 2022-09-20 Anacor Pharmaceuticals, Inc. Crystal forms of crisaborole in free form and preparation method and use thereof
EP3510021A1 (en) * 2016-09-06 2019-07-17 Indena S.p.A. Solid forms of ingenol 3-(3,5-diethylisoxazole-4-carboxylate) and method for preparing the same
EP3865136A1 (en) 2016-09-07 2021-08-18 ATEA Pharmaceuticals, Inc. 2'-substituted-n6-substituted purine nucleotides for corona virus treatment
US10336679B2 (en) * 2016-10-24 2019-07-02 Syneurx International (Taiwan) Corp. Polymorphic forms of sodium benzoate and uses thereof
US11369579B2 (en) 2016-10-24 2022-06-28 Syneurx International (Taiwan) Corp. Polymorphic forms of sodium benzoate and uses thereof
IL269667B2 (en) * 2017-03-30 2024-09-01 Merck Patent GmbH Solid forms of (s)-[2-chloro-4-fluoro-5-(7-morpholin-4-ylquinazolin-4-yl)phenyl]-(6-methoxy-pyridazin-3-yl) methanol, its preparation and pharmaceutical compositions containing them
CA3081945A1 (en) * 2017-11-22 2019-05-31 Agios Pharmaceuticals, Inc. Crystalline forms of n-(4-(4-(cyclopropylmethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide
AU2019247498A1 (en) * 2018-04-05 2020-11-26 Sumitomo Pharma Oncology, Inc. AXL kinase inhibitors and use of the same
KR20200140865A (ko) 2018-04-10 2020-12-16 아테아 파마슈티컬즈, 인크. 간경변증을 갖는 hcv 감염 환자의 치료
US20220380348A1 (en) * 2019-10-04 2022-12-01 Sumitomo Dainippon Pharma Oncology, Inc. Axl inhibitor formulations
US10874687B1 (en) 2020-02-27 2020-12-29 Atea Pharmaceuticals, Inc. Highly active compounds against COVID-19
WO2022176017A1 (ja) * 2021-02-16 2022-08-25 大塚製薬株式会社 非晶質体及び当該非晶質体を含む組成物
MX2023014898A (es) 2021-06-17 2024-04-29 Atea Pharmaceuticals Inc Terapia combinada anti-vhc ventajosa.
WO2023228905A1 (ja) 2022-05-23 2023-11-30 国立大学法人名古屋工業大学 湿式紡糸法を用いて無機フィラー粒子を含有する生分解性繊維材料を連続的に製造する方法、及びその方法で製造された綿形状の骨再生材料

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4223153A (en) 1979-02-09 1980-09-16 Eli Lilly And Company Crystalline forms of N-2-(6-methoxy)benzothiazolyl N'-phenyl urea
IT1165253B (it) 1979-07-12 1987-04-22 Blasinachim Spa Procedimento di fabbricazione di acido chenodesossicolico cristallino puro
US4486425A (en) * 1980-09-30 1984-12-04 Sankyo Company Limited 7-[2-(2-Aminothiazol-4-yl)-2-(syn)-methoxyiminoacetamido]-3-methoxymethyl-3-cephem-4-carboxylates
YU44680B (en) * 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile
IL100091A (en) 1990-12-12 1998-08-16 Zeneca Ltd Pharmaceutical compositions containing a physical form of n-[4-[5-(cyclopentyloxycarbonyl)amino-1-methyl indol-3-yl-methyl]-2-methylbenzenesulpho-namide and process for their preparation
EP0531875B1 (de) * 1991-09-07 2004-03-24 Aventis Pharma Deutschland GmbH Diastereomer des 3-Cephem-4-carbonsäure-1-(-isopropoxycarbonyloxy)ethylesters und Verfahren zu dessen Herstellung
US5248699A (en) 1992-08-13 1993-09-28 Pfizer Inc. Sertraline polymorph
AT413383B (de) * 1998-01-09 2006-02-15 Sandoz Ag Verfahren zur isolierung eines diastereoisomerengemisches von cefpodoxim proxetil
KR100342943B1 (ko) * 1999-08-04 2002-07-02 민경윤 비결정질 세푸록심 악세틸 고형분산체, 이의 제조 방법 및 이를 포함하는 경구투여용 조성물

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114409665A (zh) * 2016-06-16 2022-04-29 泽农医药公司 螺-吲哚酮化合物的固态形式
CN110248951A (zh) * 2017-02-01 2019-09-17 阿堤亚制药公司 用于治疗丙型肝炎病毒的核苷酸半硫酸盐
CN110248951B (zh) * 2017-02-01 2022-10-28 阿堤亚制药公司 用于治疗丙型肝炎病毒的核苷酸半硫酸盐
CN110251467A (zh) * 2019-06-26 2019-09-20 北京济美堂医药研究有限公司 一种无定形态头孢妥仑匹酯组合物的制备方法
CN110437259A (zh) * 2019-08-14 2019-11-12 中国药科大学 头孢泊肟酯柚皮素共无定形物及其制备方法
CN110437259B (zh) * 2019-08-14 2021-12-07 中国药科大学 头孢泊肟酯柚皮素共无定形物及其制备方法

Also Published As

Publication number Publication date
IN191496B (enExample) 2003-12-06
US6602999B1 (en) 2003-08-05
EP1204667A1 (en) 2002-05-15
WO2001009143A1 (en) 2001-02-08
ZA200200692B (en) 2003-05-28
BR0012865A (pt) 2002-07-09
EP1204667A4 (en) 2002-10-30
JP2003506329A (ja) 2003-02-18
AU5839100A (en) 2001-02-19

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