CN1371381A - 改进的无定形头孢泊肟酯 - Google Patents

改进的无定形头孢泊肟酯 Download PDF

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Publication number
CN1371381A
CN1371381A CN00812246A CN00812246A CN1371381A CN 1371381 A CN1371381 A CN 1371381A CN 00812246 A CN00812246 A CN 00812246A CN 00812246 A CN00812246 A CN 00812246A CN 1371381 A CN1371381 A CN 1371381A
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CN
China
Prior art keywords
cefpodoxime proxetil
solvent
mixture
amorphous form
acetone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN00812246A
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English (en)
Chinese (zh)
Inventor
Y·库马
R·K·阿罗拉
K·辛格
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Ranbaxy Laboratories Ltd
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Ranbaxy Laboratories Ltd
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Publication date
Application filed by Ranbaxy Laboratories Ltd filed Critical Ranbaxy Laboratories Ltd
Publication of CN1371381A publication Critical patent/CN1371381A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN00812246A 1999-07-30 2000-07-24 改进的无定形头孢泊肟酯 Pending CN1371381A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1036/DEL/99 1999-07-30
IN1036DE1999 IN191496B (enExample) 1999-07-30 1999-07-30

Publications (1)

Publication Number Publication Date
CN1371381A true CN1371381A (zh) 2002-09-25

Family

ID=11092065

Family Applications (1)

Application Number Title Priority Date Filing Date
CN00812246A Pending CN1371381A (zh) 1999-07-30 2000-07-24 改进的无定形头孢泊肟酯

Country Status (9)

Country Link
US (1) US6602999B1 (enExample)
EP (1) EP1204667A4 (enExample)
JP (1) JP2003506329A (enExample)
CN (1) CN1371381A (enExample)
AU (1) AU5839100A (enExample)
BR (1) BR0012865A (enExample)
IN (1) IN191496B (enExample)
WO (1) WO2001009143A1 (enExample)
ZA (1) ZA200200692B (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110248951A (zh) * 2017-02-01 2019-09-17 阿堤亚制药公司 用于治疗丙型肝炎病毒的核苷酸半硫酸盐
CN110251467A (zh) * 2019-06-26 2019-09-20 北京济美堂医药研究有限公司 一种无定形态头孢妥仑匹酯组合物的制备方法
CN110437259A (zh) * 2019-08-14 2019-11-12 中国药科大学 头孢泊肟酯柚皮素共无定形物及其制备方法
CN114409665A (zh) * 2016-06-16 2022-04-29 泽农医药公司 螺-吲哚酮化合物的固态形式

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT408226B (de) * 1999-05-05 2001-09-25 Biochemie Gmbh Kristalliner 7-(2-(2-formylaminothiazol-4-yl)-2
EP1373276A4 (en) 2001-02-27 2005-03-02 Ranbaxy Lab Ltd PROCESS FOR THE PRODUCTION OF CEFPODOXIM PROXETIL
CA2582087A1 (en) * 2004-10-18 2006-04-27 Teva Pharmaceutical Industries Ltd. Process for preparing amorphous atorvastatin hemi-calcium by dissolving the salt in an organic solvent which is a mixture of an alcohol and a ketone and/or an ester and removing the solvent
MX2007014363A (es) * 2005-05-16 2009-04-15 Elan Pharma Int Ltd Composiciones de liberacion controlada y en forma de nanoparticulas que comprenden una cefalosporina.
KR100840132B1 (ko) * 2007-04-17 2008-06-23 재단법인서울대학교산학협력재단 포화 액체 이산화탄소를 사용한 세포독심 프록세틸의 건조
BR112015005404A2 (pt) * 2012-09-11 2017-08-22 Dr Reddys Laboratories Ltd Formas polimórficas de enzalutamida e sua preparação
EP4450130A3 (en) 2012-09-11 2025-01-08 Medivation Prostate Therapeutics LLC Formulations of enzalutamide
GEAP202215528A (en) 2015-03-06 2022-11-10 Atea Pharmaceuticals Inc B-D-2'-DEOXY-2'a-FLUORO-2'-B-C-SUBSTITUTED-2-MODIFIED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR HCV TREATMENT
WO2017046756A1 (en) * 2015-09-18 2017-03-23 Lupin Limited Proxetil and axetil esters of cefixime
US11447506B2 (en) 2016-05-09 2022-09-20 Anacor Pharmaceuticals, Inc. Crystal forms of crisaborole in free form and preparation method and use thereof
MX380022B (es) * 2016-05-09 2025-03-11 Anacor Pharmaceuticals Inc Formas cristalinas de crisaborol en forma libre, metodo de preparacion y uso de las mismas
JP2019526637A (ja) * 2016-09-06 2019-09-19 インデナ・ソチエタ・ペル・アチオニ 固体形態のインゲノール ３−（３，５−ジエチルイソオキサゾール−４−カルボキシラート）及びその調製方法
BR112019004297A2 (pt) 2016-09-07 2019-05-28 Atea Pharmaceuticals Inc método, uso de uma quantidade eficaz de um composto, composto, e, composição farmacêutica.
US10336679B2 (en) * 2016-10-24 2019-07-02 Syneurx International (Taiwan) Corp. Polymorphic forms of sodium benzoate and uses thereof
US11369579B2 (en) 2016-10-24 2022-06-28 Syneurx International (Taiwan) Corp. Polymorphic forms of sodium benzoate and uses thereof
MX394899B (es) * 2017-03-30 2025-03-24 Merck Patent Gmbh Forma solida de (s)-[2-cloro-4-fluoro-5-(7-morfolin-4-il-quinazolin-4-il)fenil]-(6-metoxi-piridazin-3-il)-metanol.
EP4285904A3 (en) * 2017-11-22 2023-12-20 Agios Pharmaceuticals, Inc. Crystalline forms of n-(4-(4-(cyclopropylmethyl) piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide
EP3773591A4 (en) * 2018-04-05 2021-12-22 Sumitomo Dainippon Pharma Oncology, Inc. AXL KINASE INHIBITORS AND THEIR USE
EP3773753A4 (en) 2018-04-10 2021-12-22 ATEA Pharmaceuticals, Inc. TREATMENT OF PATIENTS INFECTED WITH THE HEPATITIS C VIRUS WITH CIRRHOSIS
WO2021067772A1 (en) * 2019-10-04 2021-04-08 Sumitomo Dainippon Pharma Oncology, Inc. Axl inhibitor formulations
US10874687B1 (en) 2020-02-27 2020-12-29 Atea Pharmaceuticals, Inc. Highly active compounds against COVID-19
WO2022176017A1 (ja) * 2021-02-16 2022-08-25 大塚製薬株式会社 非晶質体及び当該非晶質体を含む組成物
JP2024525164A (ja) 2021-06-17 2024-07-10 アテア ファーマシューティカルズ， インコーポレイテッド 有利な抗ｈｃｖ併用療法
EP4530380A1 (en) 2022-05-23 2025-04-02 Nagoya Institute Of Technology Method for continuously producing biodegradable fiber material containing inorganic filler particles using wet spinning, and cotton-like bone regeneration material produced with said method

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4223153A (en) 1979-02-09 1980-09-16 Eli Lilly And Company Crystalline forms of N-2-(6-methoxy)benzothiazolyl N'-phenyl urea
IT1165253B (it) 1979-07-12 1987-04-22 Blasinachim Spa Procedimento di fabbricazione di acido chenodesossicolico cristallino puro
US4486425A (en) * 1980-09-30 1984-12-04 Sankyo Company Limited 7-[2-(2-Aminothiazol-4-yl)-2-(syn)-methoxyiminoacetamido]-3-methoxymethyl-3-cephem-4-carboxylates
YU44680B (en) 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile
IL100091A (en) 1990-12-12 1998-08-16 Zeneca Ltd Pharmaceutical compositions containing a physical form of n-[4-[5-(cyclopentyloxycarbonyl)amino-1-methyl indol-3-yl-methyl]-2-methylbenzenesulpho-namide and process for their preparation
EP0531875B1 (de) * 1991-09-07 2004-03-24 Aventis Pharma Deutschland GmbH Diastereomer des 3-Cephem-4-carbonsäure-1-(-isopropoxycarbonyloxy)ethylesters und Verfahren zu dessen Herstellung
US5248699A (en) 1992-08-13 1993-09-28 Pfizer Inc. Sertraline polymorph
AT413383B (de) * 1998-01-09 2006-02-15 Sandoz Ag Verfahren zur isolierung eines diastereoisomerengemisches von cefpodoxim proxetil
KR100342943B1 (ko) * 1999-08-04 2002-07-02 민경윤 비결정질 세푸록심 악세틸 고형분산체, 이의 제조 방법 및 이를 포함하는 경구투여용 조성물

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114409665A (zh) * 2016-06-16 2022-04-29 泽农医药公司 螺-吲哚酮化合物的固态形式
CN110248951A (zh) * 2017-02-01 2019-09-17 阿堤亚制药公司 用于治疗丙型肝炎病毒的核苷酸半硫酸盐
CN110248951B (zh) * 2017-02-01 2022-10-28 阿堤亚制药公司 用于治疗丙型肝炎病毒的核苷酸半硫酸盐
CN110251467A (zh) * 2019-06-26 2019-09-20 北京济美堂医药研究有限公司 一种无定形态头孢妥仑匹酯组合物的制备方法
CN110437259A (zh) * 2019-08-14 2019-11-12 中国药科大学 头孢泊肟酯柚皮素共无定形物及其制备方法
CN110437259B (zh) * 2019-08-14 2021-12-07 中国药科大学 头孢泊肟酯柚皮素共无定形物及其制备方法

Also Published As

Publication number Publication date
AU5839100A (en) 2001-02-19
BR0012865A (pt) 2002-07-09
IN191496B (enExample) 2003-12-06
EP1204667A1 (en) 2002-05-15
EP1204667A4 (en) 2002-10-30
US6602999B1 (en) 2003-08-05
ZA200200692B (en) 2003-05-28
JP2003506329A (ja) 2003-02-18
WO2001009143A1 (en) 2001-02-08

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