CN1323660C - 治疗病毒性皮肤和肿瘤疾病的药物 - Google Patents

治疗病毒性皮肤和肿瘤疾病的药物 Download PDF

Info

Publication number
CN1323660C
CN1323660C CNB028227506A CN02822750A CN1323660C CN 1323660 C CN1323660 C CN 1323660C CN B028227506 A CNB028227506 A CN B028227506A CN 02822750 A CN02822750 A CN 02822750A CN 1323660 C CN1323660 C CN 1323660C
Authority
CN
China
Prior art keywords
medicine
weight
alkyl
group
catechol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB028227506A
Other languages
English (en)
Chinese (zh)
Other versions
CN1589141A (zh
Inventor
Y·常
R·拉斯罗普
E·博姆
I·甘德－梅斯特雷恩斯特
R·格雷格
J·霍尔达克
U·莫比由斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medigene AG
Original Assignee
Medigene AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26010614&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1323660(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE10156794A external-priority patent/DE10156794B4/de
Application filed by Medigene AG filed Critical Medigene AG
Publication of CN1589141A publication Critical patent/CN1589141A/zh
Application granted granted Critical
Publication of CN1323660C publication Critical patent/CN1323660C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/25—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids with polyoxyalkylated alcohols, e.g. esters of polyethylene glycol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
CNB028227506A 2001-11-19 2002-11-18 治疗病毒性皮肤和肿瘤疾病的药物 Expired - Lifetime CN1323660C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US33170501P 2001-11-19 2001-11-19
DE10156794A DE10156794B4 (de) 2001-11-19 2001-11-19 Arzneimittel zur Behandlung von Warzen
US60/331,705 2001-11-19
DE10156794.4 2001-11-19

Publications (2)

Publication Number Publication Date
CN1589141A CN1589141A (zh) 2005-03-02
CN1323660C true CN1323660C (zh) 2007-07-04

Family

ID=26010614

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB028227506A Expired - Lifetime CN1323660C (zh) 2001-11-19 2002-11-18 治疗病毒性皮肤和肿瘤疾病的药物

Country Status (18)

Country Link
US (4) US7858662B2 (https=)
EP (2) EP1448186B1 (https=)
JP (1) JP4495459B2 (https=)
KR (1) KR100956369B1 (https=)
CN (1) CN1323660C (https=)
AT (1) ATE417611T1 (https=)
BR (1) BRPI0214256B8 (https=)
CA (1) CA2466720C (https=)
CY (1) CY1108882T1 (https=)
DE (2) DE122009000073I1 (https=)
DK (1) DK1448186T3 (https=)
ES (1) ES2319626T3 (https=)
IL (2) IL161625A0 (https=)
MX (1) MXPA04004532A (https=)
PT (1) PT1448186E (https=)
RU (1) RU2302861C3 (https=)
WO (1) WO2003043628A1 (https=)
ZA (1) ZA200403287B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107349197A (zh) * 2017-07-13 2017-11-17 黄冈师范学院 一种儿茶素在制备治疗皮肤乳头状瘤的药物上的应用

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA04004532A (es) 2001-11-19 2004-08-11 Medigene Ag Medicamento para el tratamiento de enfermedades tumorales y virales de la piel.
ITMI20030210A1 (it) * 2003-02-07 2004-08-08 Res & Innovation Soc Coop A R L Composti endocannabinoido-simili e loro impiego
US20050058673A1 (en) 2003-09-09 2005-03-17 3M Innovative Properties Company Antimicrobial compositions and methods
US7910138B2 (en) 2003-10-09 2011-03-22 Medigene Ag Use of a polyphenol for the treatment of a cancerous or precancerous lesion of the skin
US20050079235A1 (en) * 2003-10-09 2005-04-14 Eggert Stockfleth Use of a polyphenol for the treatment of actinic keratosis
KR100665315B1 (ko) 2004-03-25 2007-01-09 한국원자력연구소 신규한 갈릭산-콘쥬게이티드 리놀레산 지방 에스테르, 이의 제조방법 및 이를 함유하는 조성물
BRPI0608691A2 (pt) 2005-03-10 2010-12-07 3M Innovative Properties Company composição antimicrobiana, e, métodos para matar ou inativar microorganismos em tecido da mucosa de um mamìfero, para tratar uma lesão ou ferimento infectado, para descolonização de microorganismos, para proporcionar eficácia antimicrobiana residual sobre uma superfìcie e para tratar uma condição
WO2006099325A2 (en) 2005-03-10 2006-09-21 3M Innovative Properties Company Methods of treating ear infections
BRPI0608690B8 (pt) 2005-03-10 2021-05-25 3M Innovative Properties Co uso de uma composição antimicrobiana
EP2179722A1 (en) * 2008-10-24 2010-04-28 Heinrich-Pette-Institut für experimentelle Virologie und Immunologie Topical formation for preventing sexual transmission of viral infection
CN102949387B (zh) * 2011-08-19 2017-03-01 奥古斯塔大学研究所公司 用于治疗单纯疱疹病毒的组合物和方法
JP5796006B2 (ja) * 2011-12-14 2015-10-21 有限会社 ワーコム農業研究所 抗菌剤
RU2600033C2 (ru) * 2014-10-16 2016-10-20 Юрий Николаевич Родионов Способ получения вещества для разрушения микроциркуляторного русла удаляемого кожного образования
JP2018512450A (ja) 2015-03-19 2018-05-17 ウェンディ アン エプスタインＥＰＳＴＥＩＮ， Ｗｅｎｄｙ Ａｎｎｅ 女性の性的障害を治療するための化合物及び剤型
KR102906039B1 (ko) 2022-04-19 2025-12-29 고려대학교 산학협력단 카테콜 화합물 또는 이의 유도체 화합물을 유효성분으로 포함하는 엡스타인-바 바이러스에 대한 항바이러스용 조성물

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0087161A2 (en) * 1982-02-24 1983-08-31 Key Pharmaceuticals, Inc. Isopropylmyristate 4-alkyl-2,6-(bis-tert-butyl)-phenol medicament
US5633284A (en) * 1992-06-08 1997-05-27 Pitmy International N.V. Nitrous oxide containing dermatological composition
WO1999066897A1 (de) * 1998-06-20 1999-12-29 Beiersdorf Ag Verwendung von einem gehalt an catechinen oder einem gehalt an extrakt von grünem tee als hautbrännungsmittel
EP1005862A1 (en) * 1998-04-21 2000-06-07 Mitsui Norin Co., Ltd. Anti-chlamydia agents

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4002775A (en) * 1973-07-09 1977-01-11 Kabara Jon J Fatty acids and derivatives of antimicrobial agents
JPS55105677A (en) 1979-02-07 1980-08-13 Norin Suisansyo Chiyagiyou Shikenjo Production of catechins
JPS59219384A (ja) 1983-05-30 1984-12-10 Mitsui Norin Kk 天然抗酸化剤の製造方法
JPS6013780A (ja) 1983-07-05 1985-01-24 Mitsui Norin Kk 茶カテキン類の製造方法
JPS61238728A (ja) 1985-04-16 1986-10-24 Mitsui Norin Kk 茶葉抽出物と活性水酸化アルミニウムとの抗潰瘍性複合体
SE462894B (sv) 1985-10-28 1990-09-17 Biogram Ab Mikrokapslar, foerfarande foer framstaellning daerav samt anvaendning
US4863970A (en) * 1986-11-14 1989-09-05 Theratech, Inc. Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols
US5204089A (en) 1989-08-30 1993-04-20 Mitsui Norin Co., Ltd. Method of preventing the formation or aggrevation of dental plaque and method for reducing cariogenesis
JP2727471B2 (ja) 1989-09-14 1998-03-11 三井農林株式会社 インフルエンザウィルス感染予防剤
JP2888554B2 (ja) 1989-09-20 1999-05-10 三井農林株式会社 マイコプラズマ感染予防剤
US5318986A (en) 1989-10-19 1994-06-07 Mitsui Norin Co., Ltd. Method of inhibiting the activity of α-amylase
US5358713A (en) 1990-02-23 1994-10-25 Mitsui Norin Co., Ltd. Method of preventing the transmission of infection caused by methicillin-resistant Staphylococcus aureus
JP3019996B2 (ja) 1990-03-01 2000-03-15 三井農林株式会社 白癬治療剤
JPH04253918A (ja) 1991-02-05 1992-09-09 Mitsui Norin Kk 血糖上昇抑制剤
US5306486A (en) 1993-03-01 1994-04-26 Elizabeth Arden Co., Division Of Conopco, Inc. Cosmetic sunscreen composition containing green tea and a sunscreen
JP3333584B2 (ja) 1993-04-19 2002-10-15 三井農林株式会社 歯質の耐酸性強化組成物
JPH07196466A (ja) * 1993-12-29 1995-08-01 Sunstar Inc 茶の粉末を配合した化粧料組成物
US5670154A (en) 1994-01-10 1997-09-23 Mitsui Norin Co., Ltd. Reducing tyrosinase activity
FR2718022B1 (fr) 1994-04-01 1996-04-26 Roussel Uclaf Compositions cosmétiques ou dermatologiques et leur préparation.
IL115156A (en) * 1994-09-06 2000-07-16 Univ Georgia Pharmaceutical compositions for the treatment of cancer comprising 1-(2-hydroxymethyl-1,3-dioxolan-4-yl) cytosines
JP2718653B2 (ja) 1995-01-31 1998-02-25 日本配合飼料株式会社 新規卵および卵質改良方法
IT1275905B1 (it) 1995-03-14 1997-10-24 Indena Spa Frazioni polifenoliche di te', loro uso e formulazioni che le contengono
US5888527A (en) 1995-05-11 1999-03-30 Matsushita Seiko Co., Ltd. Gargling cup, antiviral mask, antiviral filter, antifungal, antibacterial, and antiviral filter air cleaner and air-cleaner humidifier
GB2300578B (en) 1995-05-11 1998-01-14 Matsushita Seiko Kk Gargling cup,antiviral mask,antiviral filter,antifungal,antibacterial,and antiviral filter air cleaner and air-cleaner-humidifier
JPH09132532A (ja) 1995-09-06 1997-05-20 Mitsui Norin Kk 抗生物質の抗菌力増強方法
US6197806B1 (en) * 1995-12-20 2001-03-06 Nippon Zoki Pharmaceutical Co., Ltd. Eliminating agent for activated oxygen and free radicals
US6127393A (en) * 1995-12-29 2000-10-03 Novactyl, Inc. Antiproliferative, antiinfective, antiinflammatory, autologous immunization agent and method
US5804567A (en) 1996-07-18 1998-09-08 Cancer Institute (Hospital), Chinese Academy Of Medical Sciences Method of increasing the effectiveness of anti-metabolites
US6337320B1 (en) 1996-10-11 2002-01-08 Thione International, Inc. Reparatives for ultraviolet radiation skin damage
DE69739583D1 (de) 1996-11-14 2009-10-29 Lipomedica Ehf Topische zusammensetzungen enthaltend als therapeutisch aktiven wirkstoff ein monoglycerid zur behandlung von schleimhautinfektionen
US6197808B1 (en) 1996-11-18 2001-03-06 Cancer Instititute (Hospital), Chinese Academy Of Medical Sciences Methods for treating hyperplasia
US5968973A (en) 1996-11-18 1999-10-19 Cancer Institute (Hospital), Chinese Academy Of Medical Sciences Method for treating hyperplasia
JP3213557B2 (ja) * 1996-11-18 2001-10-02 三井農林株式会社 茶カテキンを有効成分として含有する尖圭コンジローマ治療剤
US20020198161A1 (en) 1997-02-20 2002-12-26 Douglas E. Brash Therapeutic uses of antioxidants
JP3202938B2 (ja) 1997-03-18 2001-08-27 三井農林株式会社 チューインガム及びその製造法
US5910308A (en) 1997-03-19 1999-06-08 Sante International Inc. Herbal extract composition containing gynostemma pentaphyllum, crataegus pinnatifida and camellia sinensis
US6372234B1 (en) 1997-05-27 2002-04-16 Sembiosys Genetics Inc. Products for topical applications comprising oil bodies
KR100269520B1 (ko) * 1997-07-29 2000-10-16 구본준 박막트랜지스터, 액정표시장치와 그 제조방법
US6696484B2 (en) 1997-10-31 2004-02-24 University Of Chicago Office Of Technology And Intellectual Property Method and compositions for regulation of 5-alpha reductase activity
EP1027045A4 (en) 1997-10-31 2004-12-08 Arch Dev Corp METHODS AND COMPILATIONS FOR REGULATING S-ALPHA REDUCTASE ACTIVITY
US20020006447A1 (en) 1998-04-21 2002-01-17 Mitsui Norin Co., Ltd. Anti-chlamydia agent
SE9803929D0 (sv) 1998-11-18 1998-11-18 Medivir Ab Antiviral formulation
KR100319973B1 (ko) * 1998-12-05 2002-04-22 이인수 녹차카테킨을 유효성분으로 하는 자궁경부 상피내종양 예방 또는 치료제 조성물
US6210679B1 (en) 1999-01-07 2001-04-03 Hauser, Inc. Method for isolation of caffeine-free catechins from green tea
DE19958159A1 (de) * 1999-12-02 2001-06-07 Degussa Neue für das glk-Gen codierende Nukleotidsequenzen
DE19962369A1 (de) 1999-12-23 2001-06-28 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an Catechinen oder einem Gehalt an Extrakt von grünem Tee und einem weiteren Gehalt an Ascorbinsäure
US6248341B1 (en) 2000-01-14 2001-06-19 Color Access, Inc. Method of treating topical angiogenesis-related disorders
US20020031535A1 (en) 2000-09-11 2002-03-14 Sheffield Felix H. Topical formulation to treat skin disorders
US6713506B2 (en) 2000-10-11 2004-03-30 University Of South Florida Tea polyphenol esters and analogs thereof for cancer prevention and treatment
MXPA04004532A (es) 2001-11-19 2004-08-11 Medigene Ag Medicamento para el tratamiento de enfermedades tumorales y virales de la piel.
US20030143165A1 (en) 2002-01-25 2003-07-31 Allan Evans NSAID-containing topical formulations that demonstrate chemopreventive activity
US20030166583A1 (en) 2002-02-22 2003-09-04 Oliver Yoa-Pu Hu Dermal cytochrome P450 1A inhibitors and enhancers
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
BRPI0204130B8 (pt) 2002-09-18 2021-05-25 Fund De Amparo A Pesquisa Do Estado De Sao Paulo Fapesp composição gel à base de extrato de pothomorphe umbellata, seus usos e método cosmético não-terapêutico.
WO2004053097A2 (en) 2002-12-10 2004-06-24 Medical College Of Georgia Research Institute, Inc. Chemopreventive and therapeutic aspects of polyphenolic compositions and assays
WO2004080293A2 (en) 2003-03-13 2004-09-23 3M Innovative Properties Company Methods for diagnosing skin lesions
US20050079235A1 (en) 2003-10-09 2005-04-14 Eggert Stockfleth Use of a polyphenol for the treatment of actinic keratosis
US7910138B2 (en) 2003-10-09 2011-03-22 Medigene Ag Use of a polyphenol for the treatment of a cancerous or precancerous lesion of the skin

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0087161A2 (en) * 1982-02-24 1983-08-31 Key Pharmaceuticals, Inc. Isopropylmyristate 4-alkyl-2,6-(bis-tert-butyl)-phenol medicament
US5633284A (en) * 1992-06-08 1997-05-27 Pitmy International N.V. Nitrous oxide containing dermatological composition
EP1005862A1 (en) * 1998-04-21 2000-06-07 Mitsui Norin Co., Ltd. Anti-chlamydia agents
WO1999066897A1 (de) * 1998-06-20 1999-12-29 Beiersdorf Ag Verwendung von einem gehalt an catechinen oder einem gehalt an extrakt von grünem tee als hautbrännungsmittel

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107349197A (zh) * 2017-07-13 2017-11-17 黄冈师范学院 一种儿茶素在制备治疗皮肤乳头状瘤的药物上的应用

Also Published As

Publication number Publication date
IL161625A0 (en) 2004-09-27
US20050032895A1 (en) 2005-02-10
CN1589141A (zh) 2005-03-02
JP2005514358A (ja) 2005-05-19
US20200054552A1 (en) 2020-02-20
PT1448186E (pt) 2009-03-24
KR20050044344A (ko) 2005-05-12
EP2055300B1 (de) 2016-01-27
EP2055300A3 (de) 2010-05-12
US20180193254A1 (en) 2018-07-12
MXPA04004532A (es) 2004-08-11
ZA200403287B (en) 2005-07-27
AU2002356673A1 (en) 2003-06-10
US20110009481A1 (en) 2011-01-13
DK1448186T3 (da) 2009-04-14
RU2004118667A (ru) 2005-04-10
BRPI0214256B1 (pt) 2016-06-28
DE50213137D1 (de) 2009-01-29
ES2319626T3 (es) 2009-05-11
CA2466720A1 (en) 2003-05-30
CY1108882T1 (el) 2014-07-02
US7858662B2 (en) 2010-12-28
EP1448186B1 (de) 2008-12-17
RU2302861C2 (ru) 2007-07-20
EP2055300A2 (de) 2009-05-06
US10434059B2 (en) 2019-10-08
HK1131048A1 (zh) 2010-03-12
EP1448186A1 (de) 2004-08-25
BR0214256A (pt) 2004-09-21
IL161625A (en) 2010-05-31
US9770406B2 (en) 2017-09-26
DE122009000073I1 (de) 2010-03-25
KR100956369B1 (ko) 2010-05-10
BRPI0214256B8 (pt) 2021-05-25
RU2302861C3 (ru) 2017-04-14
ATE417611T1 (de) 2009-01-15
WO2003043628A1 (de) 2003-05-30
HK1073788A1 (en) 2005-10-21
CA2466720C (en) 2010-02-09
JP4495459B2 (ja) 2010-07-07

Similar Documents

Publication Publication Date Title
US10434059B2 (en) Medicament for the treatment of viral skin and tumour diseases
US9782426B2 (en) Anti-viral therapeutic composition
CN1907276A (zh) 羟基苯甲酸酯及其类似物在制备预防和治疗病毒性感染药物中的应用
ES2569395T3 (es) Fármaco que contiene miristato de isopropilo y una catequina
US20210196676A1 (en) Treatment of viral infections and virally associated lesions with sequiterpene lactones
HK1073788B (en) Medicament for the treatment of viral skin and tumour diseases
CN100428930C (zh) 对羟基苯甲酸及其类似物在制备预防和治疗皮肤黏膜病毒性感染药物中的应用
CN101342166B (zh) 羟基苯甲酸酯及其类似物在制备预防和治疗乙型肝炎病毒的药物中的应用
CN1290493C (zh) 皮肤病毒感染的局部治疗
US20200022933A1 (en) Surfactants and compositions for treatment of viral skin conditions
HK1131048B (en) Medicament comprising isopropylmyristate and a catechin
JPWO2004069261A1 (ja) 抗ヘルペスウイルス外用製剤の製造方法
CN1843419A (zh) 一种治疗皮肤病的外用中药组合物
CN1835770A (zh) 薰草菌素的药用组合物

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1073788

Country of ref document: HK

C14 Grant of patent or utility model
GR01 Patent grant
REG Reference to a national code

Ref country code: HK

Ref legal event code: GR

Ref document number: 1073788

Country of ref document: HK

CX01 Expiry of patent term
CX01 Expiry of patent term

Granted publication date: 20070704