CN1304378C - 用于控制寄生虫的苯并咪唑－或吲哚－氨基乙腈衍生物 - Google Patents

用于控制寄生虫的苯并咪唑－或吲哚－氨基乙腈衍生物 Download PDF

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Publication number
CN1304378C
CN1304378C CNB028241053A CN02824105A CN1304378C CN 1304378 C CN1304378 C CN 1304378C CN B028241053 A CNB028241053 A CN B028241053A CN 02824105 A CN02824105 A CN 02824105A CN 1304378 C CN1304378 C CN 1304378C
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Expired - Fee Related
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CNB028241053A
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English (en)
Chinese (zh)
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CN1599725A (zh
Inventor
P·迪克雷
T·格贝尔
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Novartis AG
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Novartis AG
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Publication of CN1599725A publication Critical patent/CN1599725A/zh
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Publication of CN1304378C publication Critical patent/CN1304378C/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/10—Radicals substituted by halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
CNB028241053A 2001-11-14 2002-11-13 用于控制寄生虫的苯并咪唑－或吲哚－氨基乙腈衍生物 Expired - Fee Related CN1304378C (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH21032001 2001-11-14
CH2103/2001 2001-11-14
CH2103/01 2001-11-14

Publications (2)

Publication Number Publication Date
CN1599725A CN1599725A (zh) 2005-03-23
CN1304378C true CN1304378C (zh) 2007-03-14

Family

ID=4567523

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB028241053A Expired - Fee Related CN1304378C (zh) 2001-11-14 2002-11-13 用于控制寄生虫的苯并咪唑－或吲哚－氨基乙腈衍生物

Country Status (16)

Country Link
US (1) US7279495B2 (enExample)
EP (1) EP1446386A1 (enExample)
JP (1) JP2005518351A (enExample)
KR (1) KR20050044451A (enExample)
CN (1) CN1304378C (enExample)
AR (1) AR037363A1 (enExample)
AU (1) AU2002351995B2 (enExample)
BR (1) BR0214151A (enExample)
CA (1) CA2466971A1 (enExample)
CO (1) CO5390082A1 (enExample)
MX (1) MXPA04004605A (enExample)
NZ (1) NZ532864A (enExample)
RU (1) RU2004118247A (enExample)
TW (1) TW200300140A (enExample)
WO (1) WO2003042184A1 (enExample)
ZA (1) ZA200403459B (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200409760A (en) 2002-09-11 2004-06-16 Novartis Ag Organic compounds
US20040192738A1 (en) * 2003-03-18 2004-09-30 Aventis Pharma Deutschland Gmbh 2-(Butyl-1-sulfonylamino)-N-[1(R)-(6-methoxypyridin-3-yl)propyl] benzamide, its use as a medicament, and pharmaceutical preparations comprising it
GB0402677D0 (en) * 2003-11-06 2004-03-10 Novartis Ag Organic compounds
WO2006043654A1 (ja) * 2004-10-22 2006-04-27 Nihon Nohyaku Co., Ltd. アセトニトリル誘導体及び有害生物防除剤並びにその使用方法
US20090105308A1 (en) * 2005-07-12 2009-04-23 Darren Mansfield Benzoheterocylethylcarboxamide derivatives
PE20070427A1 (es) 2005-08-30 2007-04-21 Novartis Ag Compuestos derivados de benzimidazoles sustituidos como inhibidores de tirosina quinasas
EP2155699B9 (en) 2007-05-15 2016-09-14 Merial, Inc. Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
AR072297A1 (es) 2008-06-27 2010-08-18 Novartis Ag Derivados de indol-2-il-piridin-3-ilo, composicion farmaceutica que los comprende y su uso en medicamentos para el tratamiento de enfermedades mediadas por la sintasa aldosterona.
KR101782308B1 (ko) 2008-10-21 2017-09-27 메리얼 인코포레이티드 티오아미드 화합물, 이의 제조 방법 및 사용 방법
AR074024A1 (es) 2008-11-14 2010-12-15 Merial Ltd Compuesto de arilazol-2-il-cianoetilamino enantiomericamente enriquecidos, composicion plaguicida y su uso para prevenir la infeccion parasitaria
GB0905365D0 (en) 2009-03-27 2009-05-13 Norbrook Lab Ltd A topical parasiticide composition
US8859003B2 (en) * 2009-06-05 2014-10-14 Intercontinental Great Brands Llc Preparation of an enteric release system
US20100310726A1 (en) 2009-06-05 2010-12-09 Kraft Foods Global Brands Llc Novel Preparation of an Enteric Release System
US20100307542A1 (en) * 2009-06-05 2010-12-09 Kraft Foods Global Brands Llc Method of Reducing Surface Oil on Encapsulated Material
US9968564B2 (en) 2009-06-05 2018-05-15 Intercontinental Great Brands Llc Delivery of functional compounds
BR112014026184B1 (pt) * 2012-04-20 2019-04-24 Merial, Inc. Composições parasiticídicas compreendendo derivados de benzimidazol, métodos e seus usos
US8822689B2 (en) 2012-09-19 2014-09-02 Merial Limited Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
US8859005B2 (en) 2012-12-03 2014-10-14 Intercontinental Great Brands Llc Enteric delivery of functional ingredients suitable for hot comestible applications
EP3141592B1 (en) * 2014-05-08 2020-03-11 Osaka University Heat convection-generating chip and liquid-weighing instrument
WO2015196014A1 (en) 2014-06-19 2015-12-23 Merial, Inc. Parasiticidal compositions comprising indole derivatives, methods and uses thereof
BR112021024726A2 (pt) 2019-06-07 2022-01-18 Elanco Tiergesundheit Ag Novos derivados bicíclicos

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1234177A (zh) * 1998-05-01 1999-11-10 日本农药株式会社 氨基乙腈衍生物、含该衍生物的农业和园艺杀虫剂及其用途

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1234177A (zh) * 1998-05-01 1999-11-10 日本农药株式会社 氨基乙腈衍生物、含该衍生物的农业和园艺杀虫剂及其用途

Also Published As

Publication number Publication date
BR0214151A (pt) 2004-09-14
MXPA04004605A (es) 2005-03-07
US7279495B2 (en) 2007-10-09
NZ532864A (en) 2005-11-25
CA2466971A1 (en) 2003-05-22
AU2002351995B2 (en) 2006-08-10
KR20050044451A (ko) 2005-05-12
RU2004118247A (ru) 2006-01-10
EP1446386A1 (en) 2004-08-18
TW200300140A (en) 2003-05-16
AR037363A1 (es) 2004-11-03
CN1599725A (zh) 2005-03-23
US20050026972A1 (en) 2005-02-03
ZA200403459B (en) 2006-11-29
CO5390082A1 (es) 2004-04-30
WO2003042184A1 (en) 2003-05-22
JP2005518351A (ja) 2005-06-23

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