CN1262667C - 利用颗粒标记物检测分析物 - Google Patents

利用颗粒标记物检测分析物 Download PDF

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Publication number
CN1262667C
CN1262667C CNB971958688A CN97195868A CN1262667C CN 1262667 C CN1262667 C CN 1262667C CN B971958688 A CNB971958688 A CN B971958688A CN 97195868 A CN97195868 A CN 97195868A CN 1262667 C CN1262667 C CN 1262667C
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CN
China
Prior art keywords
particles
light
particle
scattering
analytes
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Expired - Fee Related
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CNB971958688A
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English (en)
Chinese (zh)
Other versions
CN1223692A (zh
Inventor
J·伊格拉比德
E·E·伊格拉比德
D·E·克纳
J·T·杰克森
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GENECOM Inc
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GENECOM Inc
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Publication of CN1223692A publication Critical patent/CN1223692A/zh
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Publication of CN1262667C publication Critical patent/CN1262667C/zh
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N2015/0038—Investigating nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1493—Particle size

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CNB971958688A 1996-04-25 1997-04-17 利用颗粒标记物检测分析物 Expired - Fee Related CN1262667C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1638396P 1996-04-25 1996-04-25
US60/016,383 1996-04-25

Publications (2)

Publication Number Publication Date
CN1223692A CN1223692A (zh) 1999-07-21
CN1262667C true CN1262667C (zh) 2006-07-05

Family

ID=21776844

Family Applications (1)

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CNB971958688A Expired - Fee Related CN1262667C (zh) 1996-04-25 1997-04-17 利用颗粒标记物检测分析物

Country Status (12)

Country Link
US (1) US6214560B1 (cg-RX-API-DMAC7.html)
EP (1) EP1021554B1 (cg-RX-API-DMAC7.html)
JP (3) JP2000510582A (cg-RX-API-DMAC7.html)
CN (1) CN1262667C (cg-RX-API-DMAC7.html)
AT (1) ATE357663T1 (cg-RX-API-DMAC7.html)
AU (1) AU736340B2 (cg-RX-API-DMAC7.html)
BR (1) BR9710836A (cg-RX-API-DMAC7.html)
CA (1) CA2253710A1 (cg-RX-API-DMAC7.html)
DE (1) DE69737513T2 (cg-RX-API-DMAC7.html)
IL (1) IL126544A (cg-RX-API-DMAC7.html)
RU (1) RU2251572C2 (cg-RX-API-DMAC7.html)
WO (1) WO1997040181A1 (cg-RX-API-DMAC7.html)

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IL126544A0 (en) 1999-08-17
WO1997040181A1 (en) 1997-10-30
BR9710836A (pt) 2000-10-24
JP2009236921A (ja) 2009-10-15
DE69737513T2 (de) 2007-12-13
IL126544A (en) 2004-08-31
CN1223692A (zh) 1999-07-21
JP2000510582A (ja) 2000-08-15
CA2253710A1 (en) 1997-10-30
ATE357663T1 (de) 2007-04-15
EP1021554B1 (en) 2007-03-21
RU2251572C2 (ru) 2005-05-10
DE69737513D1 (de) 2007-05-03
AU2805697A (en) 1997-11-12
JP2007263974A (ja) 2007-10-11
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