CN1250549C - 吲哚衍生物及其作为5-ht2b和5-ht2c受体配体的应用 - Google Patents

吲哚衍生物及其作为5-ht2b和5-ht2c受体配体的应用 Download PDF

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Publication number
CN1250549C
CN1250549C CNB018213510A CN01821351A CN1250549C CN 1250549 C CN1250549 C CN 1250549C CN B018213510 A CNB018213510 A CN B018213510A CN 01821351 A CN01821351 A CN 01821351A CN 1250549 C CN1250549 C CN 1250549C
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China
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compound
dihydro
methyl
diabetes
cyclopenta
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Expired - Fee Related
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CNB018213510A
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Chinese (zh)
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CN1483034A (zh
Inventor
乔纳森·马克·本特利
米歇尔·约翰·比克迪克
保罗·哈巴森
盖·安森·肯尼特
肖恩·莱顿勒
帕特里齐奥·马太
雅克·米斯拉伊
蒂莫西·詹姆斯·莫利
让-迈尔·普兰凯尔
汉斯·理查德
斯蒂文·勒韦尔
斯文·泰勒
史蒂文·保罗·维克斯
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F Hoffmann La Roche AG
Ligand UK Research Ltd
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F Hoffmann La Roche AG
Vernalis Research Ltd
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Priority claimed from GB0031724A external-priority patent/GB0031724D0/en
Priority claimed from GB0119820A external-priority patent/GB0119820D0/en
Application filed by F Hoffmann La Roche AG, Vernalis Research Ltd filed Critical F Hoffmann La Roche AG
Publication of CN1483034A publication Critical patent/CN1483034A/zh
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Publication of CN1250549C publication Critical patent/CN1250549C/zh
Anticipated expiration legal-status Critical
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
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    • A61P11/00Drugs for disorders of the respiratory system
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    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
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    • A61P25/00Drugs for disorders of the nervous system
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    • A61P25/08Antiepileptics; Anticonvulsants
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    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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    • A61P25/20Hypnotics; Sedatives
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    • A61P25/22Anxiolytics
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    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
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    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
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    • A61P7/12Antidiuretics, e.g. drugs for diabetes insipidus
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    • A61P9/00Drugs for disorders of the cardiovascular system
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  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Emergency Medicine (AREA)
  • Addiction (AREA)
  • Nutrition Science (AREA)
  • Pulmonology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CNB018213510A 2000-12-27 2001-12-14 吲哚衍生物及其作为5-ht2b和5-ht2c受体配体的应用 Expired - Fee Related CN1250549C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0031724.8 2000-12-27
GB0031724A GB0031724D0 (en) 2000-12-27 2000-12-27 Indole derivatives
GB0119820.9 2001-08-14
GB0119820A GB0119820D0 (en) 2001-08-14 2001-08-14 Indole derivatives

Publications (2)

Publication Number Publication Date
CN1483034A CN1483034A (zh) 2004-03-17
CN1250549C true CN1250549C (zh) 2006-04-12

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CNB018213510A Expired - Fee Related CN1250549C (zh) 2000-12-27 2001-12-14 吲哚衍生物及其作为5-ht2b和5-ht2c受体配体的应用

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US (1) US6610685B2 (enExample)
EP (1) EP1347979B1 (enExample)
JP (1) JP4094950B2 (enExample)
KR (1) KR100539143B1 (enExample)
CN (1) CN1250549C (enExample)
AR (1) AR035722A1 (enExample)
AT (1) ATE369368T1 (enExample)
AU (1) AU2002228007B2 (enExample)
BR (1) BR0116605A (enExample)
CA (1) CA2432085C (enExample)
DE (1) DE60129841T2 (enExample)
ES (1) ES2291374T3 (enExample)
MX (1) MXPA03005915A (enExample)
PE (1) PE20020911A1 (enExample)
UY (1) UY27097A1 (enExample)
WO (1) WO2002051844A1 (enExample)

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ATE369368T1 (de) 2007-08-15
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DE60129841T2 (de) 2008-04-17
KR100539143B1 (ko) 2005-12-26
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AU2002228007B2 (en) 2007-06-21
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