CN1235605A - 制备萘啶化合物的方法以及新的中间体 - Google Patents

制备萘啶化合物的方法以及新的中间体 Download PDF

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Publication number
CN1235605A
CN1235605A CN97199280A CN97199280A CN1235605A CN 1235605 A CN1235605 A CN 1235605A CN 97199280 A CN97199280 A CN 97199280A CN 97199280 A CN97199280 A CN 97199280A CN 1235605 A CN1235605 A CN 1235605A
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CN
China
Prior art keywords
formula
compound
hal
chlorine
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN97199280A
Other languages
English (en)
Chinese (zh)
Inventor
S·安东斯
R·格林
T·比尔菲尔德特
B·贝茨克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1996143826 external-priority patent/DE19643826A1/de
Priority claimed from DE19648214A external-priority patent/DE19648214A1/de
Application filed by Bayer AG filed Critical Bayer AG
Publication of CN1235605A publication Critical patent/CN1235605A/zh
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/26Radicals substituted by halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
CN97199280A 1996-10-30 1997-10-17 制备萘啶化合物的方法以及新的中间体 Pending CN1235605A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19643826.8 1996-10-30
DE1996143826 DE19643826A1 (de) 1996-10-30 1996-10-30 Verfahren zur Herstellung von Naphthyridinverbindungen und neue Zwischenprodukte
DE19648214A DE19648214A1 (de) 1996-11-21 1996-11-21 Verfahren zur Herstellung von Naphthyridinverbindungen und neue Zwischenprodukte
DE19648214.3 1996-11-21

Publications (1)

Publication Number Publication Date
CN1235605A true CN1235605A (zh) 1999-11-17

Family

ID=26030644

Family Applications (1)

Application Number Title Priority Date Filing Date
CN97199280A Pending CN1235605A (zh) 1996-10-30 1997-10-17 制备萘啶化合物的方法以及新的中间体

Country Status (10)

Country Link
EP (1) EP0935600A1 (de)
JP (1) JP2001502715A (de)
KR (1) KR20000052892A (de)
CN (1) CN1235605A (de)
AU (1) AU5050898A (de)
CA (1) CA2269984A1 (de)
CZ (1) CZ154999A3 (de)
IL (1) IL129597A0 (de)
PL (1) PL332941A1 (de)
WO (1) WO1998018795A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0001054A3 (en) 1997-08-06 2001-01-29 Daiichi Asubio Pharma Co Ltd 1-aryl-1,8-naphthyridin-4-one derivative as type iv phosphodiesterase inhibitor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS274601B2 (en) * 1983-07-27 1991-09-15 Dainippon Pharmaceutical Co Method of 1,8-naphthyridine derivative production
JPS60228479A (ja) * 1984-04-26 1985-11-13 Toyama Chem Co Ltd 1,4−ジヒドロ−4−オキソナフチリジン誘導体およびその塩
DE4425647A1 (de) * 1994-07-20 1996-01-25 Bayer Ag Heterocyclyl-1-phenyl substituierte Chinoloncarbonsäuren

Also Published As

Publication number Publication date
KR20000052892A (ko) 2000-08-25
PL332941A1 (en) 1999-10-25
AU5050898A (en) 1998-05-22
CA2269984A1 (en) 1998-05-07
JP2001502715A (ja) 2001-02-27
CZ154999A3 (cs) 1999-08-11
EP0935600A1 (de) 1999-08-18
WO1998018795A1 (de) 1998-05-07
IL129597A0 (en) 2000-02-29

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WD01 Invention patent application deemed withdrawn after publication