CN1222279C - 缓释型生物粘附性阴道凝胶剂型 - Google Patents

缓释型生物粘附性阴道凝胶剂型 Download PDF

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Publication number
CN1222279C
CN1222279C CNB008059098A CN00805909A CN1222279C CN 1222279 C CN1222279 C CN 1222279C CN B008059098 A CNB008059098 A CN B008059098A CN 00805909 A CN00805909 A CN 00805909A CN 1222279 C CN1222279 C CN 1222279C
Authority
CN
China
Prior art keywords
acrylic acid
composition
therapeutic agent
agarose
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB008059098A
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English (en)
Chinese (zh)
Other versions
CN1346252A (zh
Inventor
M·J·杜拉尼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Liu Dong
Original Assignee
Biovector Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biovector Technologies Inc filed Critical Biovector Technologies Inc
Publication of CN1346252A publication Critical patent/CN1346252A/zh
Application granted granted Critical
Publication of CN1222279C publication Critical patent/CN1222279C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNB008059098A 1999-02-12 2000-02-08 缓释型生物粘附性阴道凝胶剂型 Expired - Fee Related CN1222279C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/250,123 1999-02-12
US09/250,123 US6159491A (en) 1999-02-12 1999-02-12 Prolonged release bioadhesive vaginal gel dosage form

Publications (2)

Publication Number Publication Date
CN1346252A CN1346252A (zh) 2002-04-24
CN1222279C true CN1222279C (zh) 2005-10-12

Family

ID=22946381

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB008059098A Expired - Fee Related CN1222279C (zh) 1999-02-12 2000-02-08 缓释型生物粘附性阴道凝胶剂型

Country Status (12)

Country Link
US (1) US6159491A (enExample)
EP (1) EP1150630A4 (enExample)
JP (1) JP2002536387A (enExample)
KR (1) KR20010102088A (enExample)
CN (1) CN1222279C (enExample)
AU (1) AU762677B2 (enExample)
BR (1) BR0008137A (enExample)
CA (1) CA2362561A1 (enExample)
HK (1) HK1045934B (enExample)
MX (1) MXPA01008093A (enExample)
WO (1) WO2000047144A1 (enExample)
ZA (1) ZA200106640B (enExample)

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US7494669B2 (en) 2001-02-28 2009-02-24 Carrington Laboratories, Inc. Delivery of physiological agents with in-situ gels comprising anionic polysaccharides
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US20080182841A1 (en) * 2001-10-29 2008-07-31 Levine Howard L Vaginally administered anti-dysrhythmic agents for treating pelvic pain
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CA2533358C (en) 2003-07-21 2014-03-11 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
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US8062672B2 (en) 2003-08-12 2011-11-22 Shionogi Inc. Antibiotic product, use and formulation thereof
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US20050202038A1 (en) * 2004-03-10 2005-09-15 Green Roger E. Composition and method for minimizing residual fecal matter in the perianal area
US7276486B2 (en) * 2004-03-15 2007-10-02 Kimberly-Clark Worldwide, Inc. Compositions for vaginal treatment
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AU2005287430B2 (en) * 2004-09-22 2010-09-23 Cytiva Bioprocess R&D Ab Method of preparing a chromatography matrix
AU2012200105B2 (en) * 2004-10-20 2014-11-20 Care & Pharma Perspectives Sa Bioadhesive composition with programmed release
FR2876581B1 (fr) * 2004-10-20 2007-05-18 Interpharm Dev Composition bioadhesive a liberation programmee
US20060106117A1 (en) * 2004-11-12 2006-05-18 Kimberly-Clark Worldwide, Inc. Compound and method for prevention and/or treatment of vaginal infections
US7619008B2 (en) * 2004-11-12 2009-11-17 Kimberly-Clark Worldwide, Inc. Xylitol for treatment of vaginal infections
US20060292102A1 (en) * 2004-12-10 2006-12-28 Roman Stephen B Thixotropic personal lubricant
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US20060223765A1 (en) * 2005-03-30 2006-10-05 Kimberly-Clark Worldwide, Inc. Method for inhibiting and/or treating vaginal infection
US7786176B2 (en) * 2005-07-29 2010-08-31 Kimberly-Clark Worldwide, Inc. Vaginal treatment composition containing xylitol
AU2006320538B2 (en) * 2005-11-30 2013-07-04 Endo Pharmaceuticals Inc. Treatment of xerostomia with a sulfur-containing antioxidant
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8399012B2 (en) 2006-04-17 2013-03-19 Kimberly-Clark Worldwide, Inc. Degradable therapeutic delivery device
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US9314524B2 (en) * 2007-12-31 2016-04-19 Calla Therapeutics Llc Topical formulations of Flucytosine
US11058699B2 (en) * 2008-07-01 2021-07-13 Wisconsin Alumni Research Foundation Method and compositions for inhibition of double stranded DNA viruses
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MX2013012745A (es) * 2011-05-02 2014-12-05 Aptalis Pharmatech Inc Composiciones en forma de comprmido de disolución rápida para administración vaginal.
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Also Published As

Publication number Publication date
WO2000047144A1 (en) 2000-08-17
JP2002536387A (ja) 2002-10-29
EP1150630A4 (en) 2002-06-05
HK1045934A1 (en) 2002-12-20
US6159491A (en) 2000-12-12
HK1045934B (zh) 2006-07-14
AU762677B2 (en) 2003-07-03
KR20010102088A (ko) 2001-11-15
CN1346252A (zh) 2002-04-24
AU3358100A (en) 2000-08-29
BR0008137A (pt) 2003-06-10
CA2362561A1 (en) 2000-08-17
MXPA01008093A (es) 2003-07-21
ZA200106640B (en) 2002-10-14
EP1150630A1 (en) 2001-11-07

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ASS Succession or assignment of patent right

Owner name: KEJIN BIOLOGY MEDICINE MAKING HOLDING CONTROLLING

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Address after: Room 1001, building 10, building 181, Johnston Road, Wan Chai, Hongkong, China

Patentee after: Cockin Pharmaceutical Holdings Limited

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Patentee before: Biovector Technologies, Inc.

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TR01 Transfer of patent right

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Address after: 100022, Beijing, Chaoyang District, Yongan East Lane 3

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CF01 Termination of patent right due to non-payment of annual fee