CN1221525C - 1－(氨甲基)环己基乙酸的合成方法 - Google Patents

1－(氨甲基)环己基乙酸的合成方法 Download PDF

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Publication number
CN1221525C
CN1221525C CNB998129593A CN99812959A CN1221525C CN 1221525 C CN1221525 C CN 1221525C CN B998129593 A CNB998129593 A CN B998129593A CN 99812959 A CN99812959 A CN 99812959A CN 1221525 C CN1221525 C CN 1221525C
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CN
China
Prior art keywords
alkyl
formula
general formula
acetic acid
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB998129593A
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English (en)
Chinese (zh)
Other versions
CN1325378A (zh
Inventor
蒂博尔·吉祖尔
佐尔坦妮·伦杰尔
克里茨蒂那·索洛伊
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of CN1325378A publication Critical patent/CN1325378A/zh
Application granted granted Critical
Publication of CN1221525C publication Critical patent/CN1221525C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/50—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C205/51—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CNB998129593A 1998-12-29 1999-12-23 1－(氨甲基)环己基乙酸的合成方法 Expired - Fee Related CN1221525C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUP9803034 1998-12-29
HU9803034A HU225502B1 (en) 1998-12-29 1998-12-29 Process for producing 1-(amino-metyl)-cyclohexene-acetic-acid and intermediates

Publications (2)

Publication Number Publication Date
CN1325378A CN1325378A (zh) 2001-12-05
CN1221525C true CN1221525C (zh) 2005-10-05

Family

ID=89997614

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB998129593A Expired - Fee Related CN1221525C (zh) 1998-12-29 1999-12-23 1－(氨甲基)环己基乙酸的合成方法

Country Status (18)

Country Link
US (1) US6765114B1 (enExample)
JP (1) JP2002533431A (enExample)
CN (1) CN1221525C (enExample)
AT (1) ATE250569T1 (enExample)
AU (1) AU1996300A (enExample)
BG (1) BG65056B1 (enExample)
CA (1) CA2349826C (enExample)
CZ (1) CZ301922B6 (enExample)
DE (1) DE69911646T2 (enExample)
DK (1) DK1140793T3 (enExample)
EA (1) EA003555B1 (enExample)
EE (1) EE04587B1 (enExample)
ES (1) ES2207979T3 (enExample)
HU (1) HU225502B1 (enExample)
PL (1) PL196854B1 (enExample)
SK (1) SK287019B6 (enExample)
UA (1) UA73108C2 (enExample)
WO (1) WO2000039074A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2411787C (en) * 2000-06-16 2007-03-20 Teva Pharmaceuticals Industries Ltd. Stable gabapentin having ph within a controlled range
CN101484413B (zh) * 2006-06-30 2014-05-14 Zach系统股份公司 制备加巴喷丁的方法
US20110190393A1 (en) * 2008-06-03 2011-08-04 Generics (Uk) Limited Novel and efficient method for the synthesis of an amino acid
CN104974037B (zh) * 2014-04-13 2019-04-30 江苏康缘药业股份有限公司 一种含羧基多羰基姜黄素衍生物及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3253039A (en) * 1962-02-05 1966-05-24 Engelhard Ind Inc Catalytic hydrogenation of organic nitrocompounds
US3594419A (en) * 1968-04-15 1971-07-20 Gulf Research Development Co Process for converting nitroparaffins to amines
US3766271A (en) * 1971-03-04 1973-10-16 Texaco Inc Homogeneous catalysts useful in the reduction of nitroparaffins to amines
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US4894476A (en) * 1988-05-02 1990-01-16 Warner-Lambert Company Gabapentin monohydrate and a process for producing the same
DE3928183A1 (de) * 1989-08-25 1991-02-28 Goedecke Ag Lactamfreie cyclische aminosaeuren
DE3928182A1 (de) * 1989-08-25 1991-02-28 Goedecke Ag Verfahren zur herstellung von gabapentin
FI905584L (fi) 1989-11-16 1991-05-17 Lonza Ag Foerfarande foer framstaellning av 1-(aminometyl)cyklohexanaettikssyra.
ATE323067T1 (de) * 1997-10-27 2006-04-15 Warner Lambert Co Zyklische aminosäuren und deren derivate als arzneimittel

Also Published As

Publication number Publication date
BG105491A (en) 2001-12-29
AU1996300A (en) 2000-07-31
EE200100295A (et) 2002-12-16
CZ20012070A3 (cs) 2001-09-12
HUP9803034A2 (hu) 2001-02-28
BG65056B1 (bg) 2007-01-31
ATE250569T1 (de) 2003-10-15
CA2349826A1 (en) 2000-07-06
HU225502B1 (en) 2007-01-29
WO2000039074A1 (en) 2000-07-06
PL196854B1 (pl) 2008-02-29
US6765114B1 (en) 2004-07-20
DE69911646T2 (de) 2004-07-08
ES2207979T3 (es) 2004-06-01
CZ301922B6 (cs) 2010-07-28
SK287019B6 (sk) 2009-09-07
CA2349826C (en) 2009-05-12
EE04587B1 (et) 2006-02-15
PL348461A1 (en) 2002-05-20
SK9372001A3 (en) 2002-01-07
DK1140793T3 (da) 2004-02-02
EA003555B1 (ru) 2003-06-26
UA73108C2 (en) 2005-06-15
EA200100723A1 (ru) 2001-12-24
CN1325378A (zh) 2001-12-05
JP2002533431A (ja) 2002-10-08
DE69911646D1 (de) 2003-10-30
HU9803034D0 (en) 1999-02-01

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C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20051005

Termination date: 20101223