CN1199733A - 旋光的反式－3－取代的缩水甘油酸酯的制备方法 - Google Patents

旋光的反式－3－取代的缩水甘油酸酯的制备方法 Download PDF

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Publication number
CN1199733A
CN1199733A CN98108069A CN98108069A CN1199733A CN 1199733 A CN1199733 A CN 1199733A CN 98108069 A CN98108069 A CN 98108069A CN 98108069 A CN98108069 A CN 98108069A CN 1199733 A CN1199733 A CN 1199733A
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CN
China
Prior art keywords
isomer
ester
solution
ester compound
mpgm
Prior art date
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Pending
Application number
CN98108069A
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English (en)
Chinese (zh)
Inventor
古井正胜
古谷敏行
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
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Tanabe Seiyaku Co Ltd
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Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of CN1199733A publication Critical patent/CN1199733A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D301/00—Preparation of oxiranes
    • C07D301/32—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Epoxy Compounds (AREA)
CN98108069A 1997-02-27 1998-02-26 旋光的反式－3－取代的缩水甘油酸酯的制备方法 Pending CN1199733A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP4337897 1997-02-27
JP43378/97 1997-02-27
JP34166897 1997-12-11
JP341668/97 1997-12-11

Publications (1)

Publication Number Publication Date
CN1199733A true CN1199733A (zh) 1998-11-25

Family

ID=26383135

Family Applications (1)

Application Number Title Priority Date Filing Date
CN98108069A Pending CN1199733A (zh) 1997-02-27 1998-02-26 旋光的反式－3－取代的缩水甘油酸酯的制备方法

Country Status (11)

Country Link
US (2) US5998637A (enExample)
EP (1) EP0861834A1 (enExample)
KR (1) KR19980071725A (enExample)
CN (1) CN1199733A (enExample)
AU (1) AU5542198A (enExample)
BR (1) BR9800777A (enExample)
ID (1) ID19935A (enExample)
IL (1) IL123352A0 (enExample)
IN (1) IN183970B (enExample)
SG (1) SG64474A1 (enExample)
TW (1) TW438787B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103305583A (zh) * 2012-03-12 2013-09-18 江苏华荣生物科技有限公司 简便化提取消旋对甲氧苯基缩水甘油酸甲酯

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* Cited by examiner, † Cited by third party
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PL335347A1 (en) * 1997-02-26 2000-04-25 Lilly Co Eli Selective epoxidising process for use in production of pharmaceutic compounds
CA2353307A1 (fr) 2001-07-13 2003-01-13 Carmen Parent Appareil et procede pour le traitement des effluents gazeux
WO2004087932A2 (en) * 2003-04-02 2004-10-14 Shasun Chemicals And Drugs Limited Enzymatic resolution of (±) methyl trans-3-phenyl glycidate

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NL8801311A (nl) * 1988-05-20 1989-12-18 Stamicarbon Fenylglycidaatstereoisomeren, omzettingsprodukten daarvan met 2-nitrothiofenol en de bereiding van diltiazem.
US5008411A (en) * 1988-05-24 1991-04-16 Hoffmann-La Roche Inc. Glycidic acid ester and process of preparation
JPH0228594A (ja) * 1988-06-13 1990-01-30 Mitsubishi Nuclear Fuel Co Ltd 下部ノズルの取付装置
IT1226301B (it) * 1988-07-26 1990-12-27 Zambon Spa Processo per la preparazione di intermedi per la sintesi del diltiazem.
IL91453A0 (en) * 1988-09-02 1990-04-29 Tanabe Seiyaku Co Preparation of optically active 3-phenyl-glycidic acid esters
US6521445B1 (en) * 1988-10-26 2003-02-18 Sepracor, Inc. Process for preparing optically active glycidate esters
JP2954962B2 (ja) * 1989-02-21 1999-09-27 三共株式会社 ８位置換１，５―ベンゾチアゼピン誘導体
JPH0798813B2 (ja) 1989-04-28 1995-10-25 田辺製薬株式会社 １，５―ベンゾチアゼピン誘導体の製法
US5244803A (en) * 1989-09-13 1993-09-14 Tanabe Seiyaku Co., Ltd. Process for preparing optically active 3-phenylglycidic acid esters
JPH085869B2 (ja) * 1990-03-08 1996-01-24 田辺製薬株式会社 １，５−ベンゾチアゼピン誘導体の製法
FR2659657B1 (fr) * 1990-03-15 1994-09-23 Synthelabo Procede de preparation du (-) (2r,3s)-2,3-epoxy-3-(4-methoxyphenyl) propionate de methyle.
NL9000763A (nl) * 1990-03-31 1991-10-16 Stamicarbon Werkwijze voor het bereiden van 1,5-benzothiazepine-derivaten.
IT1249777B (it) * 1990-05-17 1995-03-18 Zambon Spa Processo per la preparazione di intermedi per la sintesi del diltiazem
IT1249318B (it) * 1991-05-23 1995-02-22 Zambon Spa Processo per la preparazione di benzotiazepine per ciclizzazione con acidi fosfonici
US5378698A (en) * 1991-10-21 1995-01-03 Shionogi & Co., Ltd. Benzothiazepine derivatives
IT1255545B (it) * 1992-10-23 1995-11-09 Procedimento per la preparazione di diltiazem
JPH05202013A (ja) * 1992-01-29 1993-08-10 Kohjin Co Ltd １，５−ベンゾチアゼピン誘導体の製法
JPH05286672A (ja) * 1992-04-15 1993-11-02 Mitsubishi Electric Corp かご室振れ止め装置
JP2714315B2 (ja) * 1992-04-23 1998-02-16 田辺製薬株式会社 光学活性エポキシプロピオン酸誘導体およびその製法
JP2622251B2 (ja) * 1992-09-03 1997-06-18 田辺製薬株式会社 光学活性３−（４−メトキシフェニル）グリシッド酸エステル類化合物の製法
ZA94284B (en) * 1993-01-27 1994-08-17 Shionogi & Co Process for preparing benzothiazepine derivatives
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JP3360474B2 (ja) * 1995-03-23 2002-12-24 田辺製薬株式会社 光学活性フェニルグリシッド酸エステル類の製法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103305583A (zh) * 2012-03-12 2013-09-18 江苏华荣生物科技有限公司 简便化提取消旋对甲氧苯基缩水甘油酸甲酯

Also Published As

Publication number Publication date
US5998637A (en) 1999-12-07
MX9801569A (es) 1998-12-31
IN183970B (enExample) 2000-05-27
ID19935A (id) 1998-08-27
IL123352A0 (en) 1998-09-24
KR19980071725A (ko) 1998-10-26
AU5542198A (en) 1998-09-03
TW438787B (en) 2001-06-07
SG64474A1 (en) 1999-04-27
EP0861834A1 (en) 1998-09-02
US6197953B1 (en) 2001-03-06
BR9800777A (pt) 2000-03-14

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