DK0702009T3 - Fremgangsmåde til fremstilling af farmaceutisk aktive benzothiazepinderivater - Google Patents

Fremgangsmåde til fremstilling af farmaceutisk aktive benzothiazepinderivater

Info

Publication number
DK0702009T3
DK0702009T3 DK94114643T DK94114643T DK0702009T3 DK 0702009 T3 DK0702009 T3 DK 0702009T3 DK 94114643 T DK94114643 T DK 94114643T DK 94114643 T DK94114643 T DK 94114643T DK 0702009 T3 DK0702009 T3 DK 0702009T3
Authority
DK
Denmark
Prior art keywords
pharmaceutically active
preparation
active compounds
product
reaction
Prior art date
Application number
DK94114643T
Other languages
English (en)
Inventor
Martti Hytoenen
Original Assignee
Orion Corp Fermion
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corp Fermion filed Critical Orion Corp Fermion
Application granted granted Critical
Publication of DK0702009T3 publication Critical patent/DK0702009T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK94114643T 1994-09-16 1994-09-16 Fremgangsmåde til fremstilling af farmaceutisk aktive benzothiazepinderivater DK0702009T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94114643A EP0702009B1 (en) 1994-09-16 1994-09-16 Method for the preparation of pharmaceutically active benzothiazepine derivatives

Publications (1)

Publication Number Publication Date
DK0702009T3 true DK0702009T3 (da) 1999-02-01

Family

ID=8216292

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94114643T DK0702009T3 (da) 1994-09-16 1994-09-16 Fremgangsmåde til fremstilling af farmaceutisk aktive benzothiazepinderivater

Country Status (20)

Country Link
US (1) US5663332A (da)
EP (1) EP0702009B1 (da)
JP (1) JPH08269026A (da)
AT (1) ATE167858T1 (da)
BA (1) BA95040A (da)
CA (1) CA2158223A1 (da)
CZ (1) CZ290970B6 (da)
DE (1) DE69411387T2 (da)
DK (1) DK0702009T3 (da)
EE (1) EE03565B1 (da)
ES (1) ES2118292T3 (da)
HR (1) HRP950478B1 (da)
HU (1) HU220610B1 (da)
IL (1) IL115275A (da)
LV (1) LV11324B (da)
PL (1) PL310495A1 (da)
RU (1) RU2141957C1 (da)
SK (1) SK281219B6 (da)
YU (1) YU60395A (da)
ZA (1) ZA957703B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996038429A1 (en) * 1995-06-01 1996-12-05 Acic (Canada) Inc. Method for the manufacture of benzothiazepine derivatives
IL123352A0 (en) 1997-02-27 1998-09-24 Tanabe Seiyaku Co Process for preparing an optically active trans-3-substituted glycidic acid ester
DE102004010830A1 (de) * 2004-02-27 2005-09-15 Bioagency Ag Neue 1,4-Benzooxazepane oder 1,4-Benzothiazepane und Derivate
CN103304514B (zh) * 2013-06-28 2014-09-17 天津梅花医药有限公司 一种稳定性好的盐酸地尔硫卓化合物及药物组合物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives
JPS5899471A (ja) * 1981-12-07 1983-06-13 Tanabe Seiyaku Co Ltd ベンゾチアゼピン誘導体の新規製造法
IT1175814B (it) * 1984-03-09 1987-07-15 Luso Farmaco Inst Resine solfoniche ad attivita' terapeutica,loro preparazione e composizioni farmaceutiche che le contengono
JPS63275572A (ja) * 1987-05-01 1988-11-14 Tanabe Seiyaku Co Ltd １，５−ベンゾチアゼピン誘導体
FR2624117B1 (fr) * 1987-12-08 1991-02-22 Synthelabo Derives de hydroxy-3 (methoxy-4 phenyl)-2 (methylamino-2 ethyl)-5 dihydro-2,3 5h-benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique
FR2630109B1 (fr) * 1988-04-19 1991-11-29 Synthelabo Derives de ((n-(amino-2 oxo-2 ethyl)methylamino)-2 ethyl)-5 hydroxy-3 (methoxy-4 phenyl)-2 dihydro-2,3 5h-benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique
US5002942A (en) * 1988-07-25 1991-03-26 Sankyo Company, Limited 1,5-benzothiazepine derivatives, their preparation and their use in the treatment of cardiovascular disorders
FR2653122B1 (fr) * 1989-10-17 1994-04-15 Synthelabo Derives de 5-[2-[[2-amino-2-oxoethyl]methylamino]ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5(5h)-benzothiazepine-4-one, leur preparation et leur application en therapeutique.
IT1240686B (it) * 1990-04-27 1993-12-17 Luso Farmaco Inst Derivati 1,5-benzotiazepinonici, loro preparazione e uso farmaceutico
IT1244878B (it) * 1990-12-11 1994-09-12 Lusochimica Spa Processo per la preparazione del (+)-cis-3-(acetossi)-5-!2-( dimetilammino)etil!-2,3-diidro-2-(4-metossifenil)-1,5-benzotiazepin- 4-(5h)-one cloridrato

Also Published As

Publication number Publication date
HUT76924A (hu) 1998-01-28
LV11324A (lv) 1996-06-20
YU60395A (sh) 1998-09-18
CA2158223A1 (en) 1996-03-17
HRP950478A2 (en) 1997-06-30
ATE167858T1 (de) 1998-07-15
EP0702009A1 (en) 1996-03-20
HRP950478B1 (en) 1999-10-31
SK281219B6 (sk) 2001-01-18
EP0702009B1 (en) 1998-07-01
HU9502710D0 (en) 1995-11-28
SK114195A3 (en) 1996-06-05
DE69411387T2 (de) 1999-02-25
IL115275A0 (en) 1995-12-31
LV11324B (en) 1996-10-20
DE69411387D1 (de) 1998-08-06
ES2118292T3 (es) 1998-09-16
HU220610B1 (hu) 2002-03-28
US5663332A (en) 1997-09-02
EE03565B1 (et) 2001-12-17
ZA957703B (en) 1996-04-24
IL115275A (en) 2000-06-01
JPH08269026A (ja) 1996-10-15
BA95040A (bs) 1998-12-28
EE9500050A (et) 1996-04-15
RU2141957C1 (ru) 1999-11-27
CZ237295A3 (en) 1996-04-17
CZ290970B6 (cs) 2002-11-13
PL310495A1 (en) 1996-03-18

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