CN1195872C - 通过连接经编码的衔接子进行测序 - Google Patents

通过连接经编码的衔接子进行测序 Download PDF

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Publication number
CN1195872C
CN1195872C CNB971971013A CN97197101A CN1195872C CN 1195872 C CN1195872 C CN 1195872C CN B971971013 A CNB971971013 A CN B971971013A CN 97197101 A CN97197101 A CN 97197101A CN 1195872 C CN1195872 C CN 1195872C
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China
Prior art keywords
oligonucleotide
polynucleotide
nucleotide
marker
chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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CNB971971013A
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English (en)
Chinese (zh)
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CN1230226A (zh
Inventor
G·阿尔布雷克特
S·布伦纳
D·H·劳埃德
R·B·杜布里奇
M·C·帕拉斯
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Solexa Inc
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Lynx Therapeutics Inc
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Priority claimed from US08/659,453 external-priority patent/US5846719A/en
Application filed by Lynx Therapeutics Inc filed Critical Lynx Therapeutics Inc
Publication of CN1230226A publication Critical patent/CN1230226A/zh
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C12Q1/6855—Ligating adaptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
CNB971971013A 1996-06-06 1997-06-02 通过连接经编码的衔接子进行测序 Expired - Lifetime CN1195872C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/659,453 1996-06-06
US08/659,453 US5846719A (en) 1994-10-13 1996-06-06 Oligonucleotide tags for sorting and identification
US68958796A 1996-08-12 1996-08-12
US08/689,587 1996-08-12

Publications (2)

Publication Number Publication Date
CN1230226A CN1230226A (zh) 1999-09-29
CN1195872C true CN1195872C (zh) 2005-04-06

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Family Applications (1)

Application Number Title Priority Date Filing Date
CNB971971013A Expired - Lifetime CN1195872C (zh) 1996-06-06 1997-06-02 通过连接经编码的衔接子进行测序

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EP (1) EP0923650B1 (cg-RX-API-DMAC7.html)
JP (1) JP4124377B2 (cg-RX-API-DMAC7.html)
CN (1) CN1195872C (cg-RX-API-DMAC7.html)
AT (1) ATE356221T1 (cg-RX-API-DMAC7.html)
AU (1) AU733782B2 (cg-RX-API-DMAC7.html)
CA (1) CA2256700A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ397998A3 (cg-RX-API-DMAC7.html)
DE (1) DE69737450T2 (cg-RX-API-DMAC7.html)
HU (1) HUP0003944A3 (cg-RX-API-DMAC7.html)
NO (1) NO985698L (cg-RX-API-DMAC7.html)
PL (1) PL331513A1 (cg-RX-API-DMAC7.html)
WO (1) WO1997046704A1 (cg-RX-API-DMAC7.html)

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HUP0003944A2 (en) 2001-03-28
AU3374097A (en) 1998-01-05
JP2000515006A (ja) 2000-11-14
DE69737450T2 (de) 2007-11-29
NO985698D0 (no) 1998-12-04
CZ397998A3 (cs) 1999-07-14
JP4124377B2 (ja) 2008-07-23
EP0923650A1 (en) 1999-06-23
ATE356221T1 (de) 2007-03-15
NO985698L (no) 1999-02-08
EP0923650B1 (en) 2007-03-07
DE69737450D1 (de) 2007-04-19
PL331513A1 (en) 1999-07-19
WO1997046704A1 (en) 1997-12-11
CN1230226A (zh) 1999-09-29
HUP0003944A3 (en) 2003-08-28
AU733782B2 (en) 2001-05-24
CA2256700A1 (en) 1997-12-11
HK1021206A1 (en) 2000-06-02

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Granted publication date: 20050406