ATE356221T1 - Sequenzierung durch ligation kodierter adapter - Google Patents
Sequenzierung durch ligation kodierter adapterInfo
- Publication number
- ATE356221T1 ATE356221T1 AT97929757T AT97929757T ATE356221T1 AT E356221 T1 ATE356221 T1 AT E356221T1 AT 97929757 T AT97929757 T AT 97929757T AT 97929757 T AT97929757 T AT 97929757T AT E356221 T1 ATE356221 T1 AT E356221T1
- Authority
- AT
- Austria
- Prior art keywords
- encoded
- ligation
- protruding strands
- ligated
- target polynucleotide
- Prior art date
Links
- 238000007841 sequencing by ligation Methods 0.000 title 1
- 230000000295 complement effect Effects 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- 238000012300 Sequence Analysis Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C12Q1/6855—Ligating adaptors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/659,453 US5846719A (en) | 1994-10-13 | 1996-06-06 | Oligonucleotide tags for sorting and identification |
| US68958796A | 1996-08-12 | 1996-08-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE356221T1 true ATE356221T1 (de) | 2007-03-15 |
Family
ID=27097828
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97929757T ATE356221T1 (de) | 1996-06-06 | 1997-06-02 | Sequenzierung durch ligation kodierter adapter |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0923650B1 (de) |
| JP (1) | JP4124377B2 (de) |
| CN (1) | CN1195872C (de) |
| AT (1) | ATE356221T1 (de) |
| AU (1) | AU733782B2 (de) |
| CA (1) | CA2256700A1 (de) |
| CZ (1) | CZ397998A3 (de) |
| DE (1) | DE69737450T2 (de) |
| HU (1) | HUP0003944A3 (de) |
| NO (1) | NO985698L (de) |
| PL (1) | PL331513A1 (de) |
| WO (1) | WO1997046704A1 (de) |
Families Citing this family (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE43097E1 (en) | 1994-10-13 | 2012-01-10 | Illumina, Inc. | Massively parallel signature sequencing by ligation of encoded adaptors |
| ATE466109T1 (de) * | 1995-06-07 | 2010-05-15 | Solexa Inc | Verfahren zur verbesserung der effizienz der polynukleotidsequenzierung |
| GB9620769D0 (en) * | 1996-10-04 | 1996-11-20 | Brax Genomics Ltd | Nucleic acid sequencing |
| US5888737A (en) * | 1997-04-15 | 1999-03-30 | Lynx Therapeutics, Inc. | Adaptor-based sequence analysis |
| CA2291180A1 (en) | 1997-05-23 | 1998-11-26 | Lynx Therapeutics, Inc. | System and apparatus for sequential processing of analytes |
| US6607878B2 (en) | 1997-10-06 | 2003-08-19 | Stratagene | Collections of uniquely tagged molecules |
| US6265163B1 (en) | 1998-01-09 | 2001-07-24 | Lynx Therapeutics, Inc. | Solid phase selection of differentially expressed genes |
| JP3944996B2 (ja) | 1998-03-05 | 2007-07-18 | 株式会社日立製作所 | Ｄｎａプローブアレー |
| WO1999067641A2 (en) | 1998-06-24 | 1999-12-29 | Illumina, Inc. | Decoding of array sensors with microspheres |
| US6480791B1 (en) * | 1998-10-28 | 2002-11-12 | Michael P. Strathmann | Parallel methods for genomic analysis |
| NO986133D0 (no) * | 1998-12-23 | 1998-12-23 | Preben Lexow | FremgangsmÕte for DNA-sekvensering |
| WO2000039333A1 (en) * | 1998-12-23 | 2000-07-06 | Jones Elizabeth Louise | Sequencing method using magnifying tags |
| JP2002540802A (ja) | 1999-04-06 | 2002-12-03 | イェール ユニバーシティ | 配列標識の固定されたアドレス分析 |
| US20060275782A1 (en) | 1999-04-20 | 2006-12-07 | Illumina, Inc. | Detection of nucleic acid reactions on bead arrays |
| WO2000075373A2 (en) | 1999-05-20 | 2000-12-14 | Illumina, Inc. | Combinatorial decoding of random nucleic acid arrays |
| US6544732B1 (en) | 1999-05-20 | 2003-04-08 | Illumina, Inc. | Encoding and decoding of array sensors utilizing nanocrystals |
| US8481268B2 (en) | 1999-05-21 | 2013-07-09 | Illumina, Inc. | Use of microfluidic systems in the detection of target analytes using microsphere arrays |
| US8080380B2 (en) | 1999-05-21 | 2011-12-20 | Illumina, Inc. | Use of microfluidic systems in the detection of target analytes using microsphere arrays |
| DE60026321D1 (de) * | 1999-08-13 | 2006-04-27 | Univ Yale New Haven | Binär kodierte sequenzmarker |
| CA2382157C (en) | 1999-08-18 | 2012-04-03 | Illumina, Inc. | Compositions and methods for preparing oligonucleotide solutions |
| DE60127939T2 (de) | 2000-02-07 | 2008-01-24 | Illumina, Inc., San Diego | Nukleinsäure-Nachweisverfahren mit universellem Priming |
| US7611869B2 (en) | 2000-02-07 | 2009-11-03 | Illumina, Inc. | Multiplexed methylation detection methods |
| EP1990428B1 (de) | 2000-02-07 | 2010-12-22 | Illumina, Inc. | Nukleinsäuredetektionsverfahren mit universellem Priming |
| US7582420B2 (en) | 2001-07-12 | 2009-09-01 | Illumina, Inc. | Multiplex nucleic acid reactions |
| US7361488B2 (en) | 2000-02-07 | 2008-04-22 | Illumina, Inc. | Nucleic acid detection methods using universal priming |
| EP1257668B1 (de) | 2000-02-16 | 2008-10-29 | Illumina, Inc. | Parallele genotypisierung mehrerer patientenproben |
| US7291460B2 (en) * | 2002-05-31 | 2007-11-06 | Verenium Corporation | Multiplexed systems for nucleic acid sequencing |
| CA2513985C (en) | 2003-01-21 | 2012-05-29 | Illumina Inc. | Chemical reaction monitor |
| JP2007525151A (ja) * | 2003-01-29 | 2007-09-06 | ４５４ コーポレーション | 一本鎖ｄｎａライブラリーの調製方法 |
| GB0308852D0 (en) * | 2003-04-16 | 2003-05-21 | Lingvitae As | Method |
| WO2005010184A1 (ja) * | 2003-07-25 | 2005-02-03 | Takara Bio Inc. | 変異の検出方法 |
| GB0324456D0 (en) | 2003-10-20 | 2003-11-19 | Isis Innovation | Parallel DNA sequencing methods |
| US7622281B2 (en) | 2004-05-20 | 2009-11-24 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for clonal amplification of nucleic acid |
| CA2596496A1 (en) | 2005-02-01 | 2006-08-10 | Agencourt Bioscience Corp. | Reagents, methods, and libraries for bead-based sequencing |
| GB0524069D0 (en) | 2005-11-25 | 2006-01-04 | Solexa Ltd | Preparation of templates for solid phase amplification |
| SG169356A1 (en) * | 2006-02-08 | 2011-03-30 | Illumina Cambridge Ltd | Method for sequencing a polynucleotide template |
| WO2007097443A1 (ja) * | 2006-02-20 | 2007-08-30 | National University Corporation Hokkaido University | Ｄｎａ塩基配列を決定する方法 |
| CN101495654A (zh) * | 2006-04-19 | 2009-07-29 | 阿普里拉股份有限公司 | 无凝胶珠基测序的试剂、方法和文库 |
| US8889348B2 (en) | 2006-06-07 | 2014-11-18 | The Trustees Of Columbia University In The City Of New York | DNA sequencing by nanopore using modified nucleotides |
| US9605307B2 (en) | 2010-02-08 | 2017-03-28 | Genia Technologies, Inc. | Systems and methods for forming a nanopore in a lipid bilayer |
| US9678055B2 (en) | 2010-02-08 | 2017-06-13 | Genia Technologies, Inc. | Methods for forming a nanopore in a lipid bilayer |
| US8324914B2 (en) | 2010-02-08 | 2012-12-04 | Genia Technologies, Inc. | Systems and methods for characterizing a molecule |
| US9121059B2 (en) | 2010-12-22 | 2015-09-01 | Genia Technologies, Inc. | Nanopore-based single molecule characterization |
| US9581563B2 (en) | 2011-01-24 | 2017-02-28 | Genia Technologies, Inc. | System for communicating information from an array of sensors |
| US9110478B2 (en) | 2011-01-27 | 2015-08-18 | Genia Technologies, Inc. | Temperature regulation of measurement arrays |
| WO2012162267A2 (en) * | 2011-05-20 | 2012-11-29 | Fluidigm Corporation | Nucleic acid encoding reactions |
| US10501791B2 (en) | 2011-10-14 | 2019-12-10 | President And Fellows Of Harvard College | Sequencing by structure assembly |
| WO2014163886A1 (en) | 2013-03-12 | 2014-10-09 | President And Fellows Of Harvard College | Method of generating a three-dimensional nucleic acid containing matrix |
| ES2991004T3 (es) | 2011-12-22 | 2024-12-02 | Harvard College | Métodos para la detección de analitos |
| ES2952728T3 (es) | 2011-12-22 | 2023-11-03 | Harvard College | Métodos para la detección de analitos |
| US8986629B2 (en) | 2012-02-27 | 2015-03-24 | Genia Technologies, Inc. | Sensor circuit for controlling, detecting, and measuring a molecular complex |
| CN102766689B (zh) * | 2012-04-17 | 2015-07-22 | 盛司潼 | 一种增加测序读长的测序方法 |
| CN104603286B (zh) * | 2012-04-24 | 2020-07-31 | Gen9股份有限公司 | 在体外克隆中分选核酸和多重制备物的方法 |
| EP2847353B1 (de) * | 2012-05-10 | 2022-01-19 | The General Hospital Corporation | Verfahren zur bestimmung einer nukleotidsequenz |
| US9914967B2 (en) | 2012-06-05 | 2018-03-13 | President And Fellows Of Harvard College | Spatial sequencing of nucleic acids using DNA origami probes |
| CA2876095A1 (en) | 2012-06-15 | 2013-12-19 | Genia Technologies, Inc. | Chip set-up and high-accuracy nucleic acid sequencing |
| US9605309B2 (en) | 2012-11-09 | 2017-03-28 | Genia Technologies, Inc. | Nucleic acid sequencing using tags |
| US9759711B2 (en) | 2013-02-05 | 2017-09-12 | Genia Technologies, Inc. | Nanopore arrays |
| US10648026B2 (en) | 2013-03-15 | 2020-05-12 | The Trustees Of Columbia University In The City Of New York | Raman cluster tagged molecules for biological imaging |
| MY177814A (en) | 2013-06-04 | 2020-09-23 | Harvard College | Rna-guided transcriptional regulation |
| ES2717756T3 (es) * | 2013-09-30 | 2019-06-25 | Qiagen Gmbh | Moléculas adaptadoras de ADN para la preparación de genotecas de ADN y método para su producción y uso |
| US9551697B2 (en) | 2013-10-17 | 2017-01-24 | Genia Technologies, Inc. | Non-faradaic, capacitively coupled measurement in a nanopore cell array |
| US9322062B2 (en) | 2013-10-23 | 2016-04-26 | Genia Technologies, Inc. | Process for biosensor well formation |
| CA2926138A1 (en) | 2013-10-23 | 2015-04-30 | Genia Technologies, Inc. | High speed molecular sensing with nanopores |
| HUE051262T2 (hu) * | 2014-01-28 | 2021-03-01 | Lanzatech New Zealand Ltd | Módszer rekombináns mirkoorganizmus elõállítására |
| AU2015210705B2 (en) * | 2014-01-31 | 2020-11-05 | Integrated Dna Technologies, Inc. | Improved methods for processing DNA substrates |
| WO2016007839A1 (en) | 2014-07-11 | 2016-01-14 | President And Fellows Of Harvard College | Methods for high-throughput labelling and detection of biological features in situ using microscopy |
| WO2016034433A1 (en) * | 2014-09-05 | 2016-03-10 | Qiagen Gmbh | Preparation of adapter-ligated amplicons |
| AU2014406026B2 (en) | 2014-09-12 | 2018-08-23 | Mgi Tech Co., Ltd. | Isolated oligonucleotide and use thereof in nucleic acid sequencing |
| WO2016058136A1 (zh) * | 2014-10-14 | 2016-04-21 | 深圳华大基因科技有限公司 | 一种接头元件和使用其构建测序文库的方法 |
| US20180044668A1 (en) * | 2014-10-14 | 2018-02-15 | Bgi Shenzhen Co., Limited | Mate pair library construction |
| US10221448B2 (en) | 2015-03-06 | 2019-03-05 | Pillar Biosciences Inc. | Selective amplification of overlapping amplicons |
| WO2017027779A1 (en) * | 2015-08-13 | 2017-02-16 | Centrillion Technology Holdings Corporation | Library construction using y-adapters and vanishing restriction sites |
| CN108474022A (zh) | 2015-11-03 | 2018-08-31 | 哈佛学院董事及会员团体 | 用于包含三维核酸的基质容积成像的设备和方法 |
| EP3390658B1 (de) | 2015-12-16 | 2022-08-03 | Standard BioTools Inc. | High-level-multiplexamplifikation |
| SG11201807444PA (en) * | 2016-03-10 | 2018-09-27 | Univ Leland Stanford Junior | Transposase-mediated imaging of the accessible genome |
| CA3210120C (en) | 2016-04-25 | 2024-04-09 | President And Fellows Of Harvard College | Hybridization chain reaction methods for in situ molecular detection |
| US11299780B2 (en) | 2016-07-15 | 2022-04-12 | The Regents Of The University Of California | Methods of producing nucleic acid libraries |
| EP4428536A3 (de) | 2016-08-31 | 2024-12-04 | President and Fellows of Harvard College | Verfahren zur kombination des nachweises von biomolekülen in einem einzigen test mit fluoreszenter in-situ-sequenzierung |
| CN109983125B (zh) | 2016-08-31 | 2024-06-04 | 哈佛学院董事及会员团体 | 生成用于通过荧光原位测序检测的核酸序列文库的方法 |
| US10550425B2 (en) | 2016-11-14 | 2020-02-04 | Agilent Technologies, Inc. | Composition and method for improving signal-to-noise in hybridization to oligonucleotide arrays |
| WO2018102064A1 (en) * | 2016-11-30 | 2018-06-07 | Microsoft Technology Licensing, Llc. | Dna random access storage system via ligation |
| KR20190140906A (ko) | 2017-04-14 | 2019-12-20 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 세포-유래 마이크로필라멘트 네트워크의 생성 방법 |
| CN107299151B (zh) * | 2017-08-28 | 2020-06-09 | 华中农业大学 | 用于鉴别稻米脂肪酸品质的dna分子标记及其应用 |
| EP3737774B1 (de) | 2018-01-12 | 2024-12-25 | Claret Bioscience, LLC | Verfahren zur analyse von nukleinsäuren |
| CN119020348A (zh) | 2018-02-05 | 2024-11-26 | 斯坦福大学托管董事会 | 用于单细胞和集合细胞的多重测量的系统和方法 |
| WO2019236726A1 (en) | 2018-06-06 | 2019-12-12 | The Regents Of The University Of California | Methods of producing nucleic acid libraries and compositions and kits for practicing same |
| SG11202101934SA (en) | 2018-07-30 | 2021-03-30 | Readcoor Llc | Methods and systems for sample processing or analysis |
| WO2020076976A1 (en) | 2018-10-10 | 2020-04-16 | Readcoor, Inc. | Three-dimensional spatial molecular indexing |
| US20220049303A1 (en) | 2020-08-17 | 2022-02-17 | Readcoor, Llc | Methods and systems for spatial mapping of genetic variants |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5102785A (en) * | 1987-09-28 | 1992-04-07 | E. I. Du Pont De Nemours And Company | Method of gene mapping |
| EP0392546A3 (de) * | 1989-04-14 | 1991-09-11 | Ro Institut Za Molekularnu Genetiku I Geneticko Inzenjerstvo | Verfahren zur Bestimmung von vollständigen oder partiellen Bestandteilen von sehr kurzen Sequenzen in Proben von Partikeln mikroskopischer Grösse mittels Hybridisierung mit Oligonukleotid-Sonden |
| US5650274A (en) * | 1993-06-25 | 1997-07-22 | Hitachi, Ltd. | DNA analyzing method |
| GB9401200D0 (en) * | 1994-01-21 | 1994-03-16 | Medical Res Council | Sequencing of nucleic acids |
| US5552278A (en) * | 1994-04-04 | 1996-09-03 | Spectragen, Inc. | DNA sequencing by stepwise ligation and cleavage |
| US5604097A (en) * | 1994-10-13 | 1997-02-18 | Spectragen, Inc. | Methods for sorting polynucleotides using oligonucleotide tags |
| WO1996041011A1 (en) * | 1995-06-07 | 1996-12-19 | Lynx Therapeutics, Inc. | Oligonucleotide tags for sorting and identification |
-
1997
- 1997-06-02 HU HU0003944A patent/HUP0003944A3/hu not_active Application Discontinuation
- 1997-06-02 PL PL97331513A patent/PL331513A1/xx unknown
- 1997-06-02 EP EP97929757A patent/EP0923650B1/de not_active Expired - Lifetime
- 1997-06-02 JP JP50075598A patent/JP4124377B2/ja not_active Expired - Lifetime
- 1997-06-02 AU AU33740/97A patent/AU733782B2/en not_active Ceased
- 1997-06-02 CA CA002256700A patent/CA2256700A1/en not_active Abandoned
- 1997-06-02 AT AT97929757T patent/ATE356221T1/de not_active IP Right Cessation
- 1997-06-02 CZ CZ983979A patent/CZ397998A3/cs unknown
- 1997-06-02 WO PCT/US1997/009472 patent/WO1997046704A1/en not_active Ceased
- 1997-06-02 DE DE69737450T patent/DE69737450T2/de not_active Expired - Lifetime
- 1997-06-02 CN CNB971971013A patent/CN1195872C/zh not_active Expired - Lifetime
-
1998
- 1998-12-04 NO NO985698A patent/NO985698L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0003944A2 (en) | 2001-03-28 |
| HUP0003944A3 (en) | 2003-08-28 |
| DE69737450T2 (de) | 2007-11-29 |
| AU3374097A (en) | 1998-01-05 |
| NO985698L (no) | 1999-02-08 |
| CN1195872C (zh) | 2005-04-06 |
| JP4124377B2 (ja) | 2008-07-23 |
| WO1997046704A1 (en) | 1997-12-11 |
| CA2256700A1 (en) | 1997-12-11 |
| EP0923650B1 (de) | 2007-03-07 |
| CZ397998A3 (cs) | 1999-07-14 |
| CN1230226A (zh) | 1999-09-29 |
| NO985698D0 (no) | 1998-12-04 |
| EP0923650A1 (de) | 1999-06-23 |
| HK1021206A1 (en) | 2000-06-02 |
| PL331513A1 (en) | 1999-07-19 |
| JP2000515006A (ja) | 2000-11-14 |
| AU733782B2 (en) | 2001-05-24 |
| DE69737450D1 (de) | 2007-04-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE356221T1 (de) | Sequenzierung durch ligation kodierter adapter | |
| ATE201238T1 (de) | Dns-sequenzierung durch stufenweise ligierung und spaltung | |
| DK0970240T3 (da) | Kunstig fejlparringshydridisering | |
| NO961165L (no) | Fremgangsmåte og kit for effektiv sekvensering av nukleinsyre | |
| MX9705961A (es) | Polimerasa de adn termoestable, modificada. | |
| ATE164883T1 (de) | Verfahren zur vorbereitung von doppel strangiger rna und seine anwendungen | |
| CA2218017A1 (en) | Dna sequencing by parallel oligonucleotide extensions | |
| CA2218476A1 (en) | Diagnostic method | |
| ATE191514T1 (de) | Sequenzierung von nukleinsäuren | |
| DE69924140D1 (de) | Bestimmung der länge von repetitiven nukleinsäuresequenzen durch eine diskontinuierliche verlängerung von startermolekülen | |
| ATE241018T1 (de) | Untersuchung von nukleotiden in loesung mit hilfe von pna-sonden | |
| DE69407187D1 (de) | Identifizierung von salmonella durch die polymerase-ketten-reaktion | |
| ATE230034T1 (de) | Verfahren zur aufreinigung von dns | |
| ATE298804T1 (de) | Verfahren zur nachweis von nukleinsäuren | |
| AU1204600A (en) | Systems and methods for sequencing by hybridization | |
| ATE195974T1 (de) | Nukleotidsequenzen die spezifisch mit einer nukleotidsequenz aus campylobacter jejuni hybridisieren | |
| HK1054572A1 (en) | Method of generation and management of unique sequences in dna production | |
| AU2002215010A1 (en) | Thermostable polymerase based on thermococcus pacificus | |
| Nelson et al. | Sequencing two DNA templates in five channels by digital compression. | |
| CN119932729A (zh) | 甲基化文库的构建方法及试剂盒 | |
| WO2001040510A3 (de) | Dynamische sequenzierung durch hybridisierung |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |