CN119409799A - 分离对癌症特异性突变具有抗原特异性的t细胞受体的方法 - Google Patents

分离对癌症特异性突变具有抗原特异性的t细胞受体的方法 Download PDF

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CN119409799A
CN119409799A CN202411616177.4A CN202411616177A CN119409799A CN 119409799 A CN119409799 A CN 119409799A CN 202411616177 A CN202411616177 A CN 202411616177A CN 119409799 A CN119409799 A CN 119409799A
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cells
amino acid
acid sequence
cancer
mutated amino
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埃里克·特兰
卢勇成
保罗·E·罗宾斯
史蒂文·A·罗森伯格
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US Department of Health and Human Services
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CN202411616177.4A 2014-10-02 2014-10-02 分离对癌症特异性突变具有抗原特异性的t细胞受体的方法 Pending CN119409799A (zh)

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CN202411616177.4A CN119409799A (zh) 2014-10-02 2014-10-02 分离对癌症特异性突变具有抗原特异性的t细胞受体的方法

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Application Number Priority Date Filing Date Title
PCT/US2014/058796 WO2016053338A1 (en) 2014-10-02 2014-10-02 Methods of isolating t cell receptors having antigenic specificity for a cancer-specific mutation
CN202411616177.4A CN119409799A (zh) 2014-10-02 2014-10-02 分离对癌症特异性突变具有抗原特异性的t细胞受体的方法
CN201480082932.3A CN107074932A (zh) 2014-10-02 2014-10-02 分离对癌症特异性突变具有抗原特异性的t细胞受体的方法

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CN201480082932.3A Pending CN107074932A (zh) 2014-10-02 2014-10-02 分离对癌症特异性突变具有抗原特异性的t细胞受体的方法

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US (2) US20170218042A1 (https=)
EP (2) EP4074333A1 (https=)
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AU (2) AU2014407539B2 (https=)
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US10973894B2 (en) 2014-10-02 2021-04-13 The United States Of America, As Represented By The Secretary, Department Of Health And Human Methods of isolating T cells having antigenic specificity for a cancer-specific mutation
EP3075389A1 (en) * 2015-03-31 2016-10-05 Technische Universität München T cell receptors and peptides derived by mutations for the treatment of cancer
US10544392B2 (en) 2015-05-01 2020-01-28 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of isolating T cells and T cell receptors having antigenic specificity for a cancer-specific mutation from peripheral blood
GB2592821B (en) 2015-07-31 2022-01-12 Univ Minnesota Modified cells and methods of therapy
WO2017048614A1 (en) 2015-09-15 2017-03-23 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of isolating tumor-reactive t cell receptors from tumor or peripheral blood
CN109843921B (zh) 2016-07-07 2023-05-26 艾欧凡斯生物治疗公司 程序性死亡1配体1(pd-l1)结合蛋白及其应用方法
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