CN1191851C - 包含胆碱结合蛋白an－末端截取物的氨基酸的多肽、由该多肽衍生的疫苗及其应用 - Google Patents

包含胆碱结合蛋白an－末端截取物的氨基酸的多肽、由该多肽衍生的疫苗及其应用 Download PDF

Info

Publication number
CN1191851C
CN1191851C CNB998108545A CN99810854A CN1191851C CN 1191851 C CN1191851 C CN 1191851C CN B998108545 A CNB998108545 A CN B998108545A CN 99810854 A CN99810854 A CN 99810854A CN 1191851 C CN1191851 C CN 1191851C
Authority
CN
China
Prior art keywords
lys
glu
polypeptide
ala
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB998108545A
Other languages
English (en)
Chinese (zh)
Other versions
CN1342088A (zh
Inventor
E·I·托曼恩
H·R·马舒尔
T·M·维泽曼
L·S·约翰逊
S·科尼格
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
St Jude Childrens Research Hospital
MedImmune LLC
Original Assignee
St Jude Childrens Research Hospital
MedImmune LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/056,019 external-priority patent/US6858706B2/en
Application filed by St Jude Childrens Research Hospital, MedImmune LLC filed Critical St Jude Childrens Research Hospital
Publication of CN1342088A publication Critical patent/CN1342088A/zh
Application granted granted Critical
Publication of CN1191851C publication Critical patent/CN1191851C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CNB998108545A 1998-04-07 1999-04-07 包含胆碱结合蛋白an－末端截取物的氨基酸的多肽、由该多肽衍生的疫苗及其应用 Expired - Fee Related CN1191851C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8087898P 1998-04-07 1998-04-07
US09/056,019 1998-04-07
US09/056,019 US6858706B2 (en) 1998-04-07 1998-04-07 Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
US60/080,878 1998-04-07

Publications (2)

Publication Number Publication Date
CN1342088A CN1342088A (zh) 2002-03-27
CN1191851C true CN1191851C (zh) 2005-03-09

Family

ID=26734874

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB998108545A Expired - Fee Related CN1191851C (zh) 1998-04-07 1999-04-07 包含胆碱结合蛋白an－末端截取物的氨基酸的多肽、由该多肽衍生的疫苗及其应用

Country Status (14)

Country Link
JP (1) JP4739521B2 (pt)
KR (1) KR100638503B1 (pt)
CN (1) CN1191851C (pt)
AU (2) AU764811B2 (pt)
BR (1) BR9909910A (pt)
CA (1) CA2326388C (pt)
HU (1) HUP0102306A3 (pt)
IL (1) IL138939A0 (pt)
MX (1) MXPA00009899A (pt)
NO (1) NO20005081L (pt)
NZ (1) NZ507983A (pt)
PL (1) PL193132B1 (pt)
TR (1) TR200003498T2 (pt)
WO (1) WO1999051188A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
EP3020411A1 (en) 2005-12-22 2016-05-18 GlaxoSmithKline Biologicals s.a. Vaccine
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
PT2167121E (pt) 2007-06-26 2015-12-02 Glaxosmithkline Biolog Sa Vacina compreendendo conjugados de polissacáridos capsulares de streptococcus pneumoniae
PT2271360E (pt) 2008-04-16 2015-12-07 Glaxosmithkline Biolog Sa Vacina
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
SG194733A1 (en) 2011-05-17 2013-12-30 Glaxosmithkline Biolog Sa Vaccine against streptococcus pneumoniae
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6592876B1 (en) * 1993-04-20 2003-07-15 Uab Research Foundation Pneumococcal genes, portions thereof, expression products therefrom, and uses of such genes, portions and products
DE69735715T2 (de) * 1996-05-01 2007-03-29 The Rockefeller University Cholin-bindendes Protein, welches als gegen Pneumokokken gerichtetes Vakzin verwendet wird
DE69737125T3 (de) * 1996-10-31 2015-02-26 Human Genome Sciences, Inc. Streptococcus pneumoniae-Antigene und Impfstoffe
US6291654B1 (en) * 1996-11-12 2001-09-18 Regents Of The University Of Minnesota Method for isolating a C3 binding protein of streptococcus pneumoniae
NZ530277A (en) * 1998-04-07 2005-08-26 Medimmune Inc Derivatives of pneumococcal choline binding proteins for vaccines
US6858706B2 (en) * 1998-04-07 2005-02-22 St. Jude Children's Research Hospital Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof

Also Published As

Publication number Publication date
BR9909910A (pt) 2002-01-15
KR20010052244A (ko) 2001-06-25
WO1999051188A2 (en) 1999-10-14
AU3479699A (en) 1999-10-25
CA2326388C (en) 2014-02-04
AU3479799A (en) 1999-10-25
KR100638503B1 (ko) 2006-10-26
JP2002516662A (ja) 2002-06-11
NZ507983A (en) 2004-03-26
AU764811B2 (en) 2003-08-28
CA2326388A1 (en) 1999-10-14
PL193132B1 (pl) 2007-01-31
CN1342088A (zh) 2002-03-27
PL347946A1 (en) 2002-04-22
NO20005081D0 (no) 2000-10-09
TR200003498T2 (tr) 2001-10-22
WO1999051188A3 (en) 2001-04-19
WO1999051188A9 (en) 2000-10-12
MXPA00009899A (es) 2002-05-08
JP4739521B2 (ja) 2011-08-03
HUP0102306A1 (hu) 2001-09-28
IL138939A0 (en) 2001-11-25
HUP0102306A3 (en) 2008-04-28
NO20005081L (no) 2000-12-06

Similar Documents

Publication Publication Date Title
CN1268745C (zh) B组链球菌抗原
CN1200731C (zh) 用作疫苗的肺炎球菌胆碱结合蛋白衍生物
CN1191362C (zh) 新颖的链球菌抗原
CN1227360C (zh) Mage家族肿瘤相关抗原衍生物及其编码核酸序列
CN1073118C (zh) C型肝炎病毒的检测方法
CN1056153C (zh) 有丝分裂发生和运动发生的肽抑制物
KR20170102905A (ko) 신규 다가 나노입자 기반 백신
CN1537164A (zh) 治疗和诊断Her-2/neu相关恶性肿瘤的组合物和方法
CN1284965A (zh) 脑膜炎奈瑟氏球菌的新表面蛋白
CN1277614A (zh) 乳房珠蛋白,一种乳房特异性乳腺癌分泌蛋白
CN1118474C (zh) 合成肽及包含其的疫苗
CN1556857A (zh) 呼吸道合胞病毒(rsv)g蛋白的新肽及其在疫苗中的应用
CN1191851C (zh) 包含胆碱结合蛋白an－末端截取物的氨基酸的多肽、由该多肽衍生的疫苗及其应用
CN1628249A (zh) 副结核分枝杆菌感染的诊断和疫苗
CN1165147A (zh) 鸟嘌呤核苷酸结合蛋白偶联受体蛋白质，其生产和应用
CN1211487C (zh) 链球菌毒素a突变体及其使用方法
CN1741818A (zh) 线虫多肽佐剂
CN1292796A (zh) Meth1和meth2多核苷酸及多肽
CN1849334A (zh) 胞内劳森氏菌亚单位疫苗
CN1204253C (zh) 奈瑟氏球菌乳铁蛋白结合蛋白
CN1150324C (zh) 一种新的人溶菌酶基因、其编码的多肽及制备方法
CN1310723A (zh) 来源于sart－1的hla－a2限制性肿瘤抗原肽
EP4248993A1 (en) New mers-cov vaccine
CN1233187A (zh) HIVp－17肽片段、含有该片段的组合物及其制造和使用方法
CN1193981A (zh) 人g蛋白偶联受体(hetgq23)

Legal Events

Date Code Title Description
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C06 Publication
PB01 Publication
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20050309

Termination date: 20170407

CF01 Termination of patent right due to non-payment of annual fee